What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high blood sugar, low blood pH, and ketoacids in either the blood or urine. The primary treatment of DKA is with intravenous fluids and insulin. Depending on the severity, insulin may be given intravenously or by injection under the skin. Usually potassium is also needed to prevent the development of low blood potassium. Throughout treatment blood sugar and potassium levels should be regularly checked. Antibiotics may be required in those with an underlying infection. In those with severely low blood pH, sodium bicarbonate may be given; however, its use is of unclear benefit and typically not recommended. Rates of DKA vary around the world. About 4% of people with type 1 diabetes in United Kingdom develop DKA a year, while in Malaysia the condition affects about 25% a year. DKA was first described in 1886 and, until the introduction of insulin therapy in the 1920s, it was almost universally fatal. The risk of death with adequate and timely treatment is currently around 1–4%. Up to 1% of children with DKA develop a complication known as cerebral edema. The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. Those who measure their glucose levels themselves may notice hyperglycemia (high blood sugar levels). In severe DKA, breathing becomes labored and of a deep, gasping character (a state referred to as "Kussmaul respiration"). The abdomen may be tender to the point that an acute abdomen may be suspected, such as acute pancreatitis, appendicitis or gastrointestinal perforation. Coffee ground vomiting (vomiting of altered blood) occurs in a minority of people; this tends to originate from erosion of the esophagus. In severe DKA, there may be confusion, lethargy, stupor or even coma (a marked decrease in the level of consciousness). On physical examination there is usually clinical evidence of dehydration, such as a dry mouth and decreased skin turgor. If the dehydration is profound enough to cause a decrease in the circulating blood volume, tachycardia (a fast heart rate) and low blood pressure may be observed. Often, a "ketotic" odor is present, which is often described as "fruity", often compared to the smell of pear drops whose scent is a ketone. If Kussmaul respiration is present, this is reflected in an increased respiratory rate.....
Diabetic Ketoacidosis In Pregnancy
Diabetic ketoacidosis is a serious metabolic complication of diabetes with high mortality if undetected. Its occurrence in pregnancy compromises both the fetus and the mother profoundly. Although predictably more common in patients with type 1 diabetes, it has been recognised in those with type 2 diabetes as well as gestational diabetes, especially with the use of corticosteroids for fetal lung maturity and β2-agonists for tocolysis.1–3 Diabetic ketoacidosis usually occurs in the second and third trimesters because of increased insulin resistance, and is also seen in newly presenting type 1 diabetes patients. With increasing practice of antepartum diabetes screening and the availability of early and frequent prenatal care/surveillance, the incidence and outcomes of diabetic ketoacidosis in pregnancy have vastly improved. However, it still remains a major clinical problem in pregnancy since it tends to occur at lower blood glucose levels and more rapidly than in non-pregnant patients often causing delay in the diagnosis. The purpose of this article is to illustrate a typical patient who may present with diabetic ketoacidosis in pregnancy and review the literature on this relative
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Clenbuterol abuse as a diet drug gained popularity a few years ago. Its side effects caused it to become a banned substance. In this interview with Medscape and Drs. McKeever and Hoffman, they break down the dangers of using Clenbuterol to gain muscle and lose weight. The original article can be found at MedScape.com To Dope or Not to Dope: Abuse of Clenbuterol as a Diet Drug: An Expert Interview With Drs. Ken McKeever and Hoffman Use and abuse. Misuse and overuse. These are topics that we have explored before in our To Dope or Not to Dope columns. Previously, we discussed the role of the team physician and why elite athletes may choose to use performance-enhancing drugs. In this column, we talk about the use of performance-enhancing drugs by the everyday weekend warrior. Clenbuterol has received substantial attention by the lay media as a miracle diet drug with only perfunctory regard to the dangers of its unsupervised use. When used appropriately under the supervision of a physician or veterinarian, clenbuterol can alleviate respiratory distress in horses and may have potential therapeutic benefits in human heart failure. However, off-label unsupervised overuse of the drug can b
Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Lowering your caloric intake and doing intermittent fasting has a ton of health benefits on both your body and your mind. Herman Hesse said in his novel, Siddhartha: Everyone can perform magic, everyone can reach his goals, if he is able to think, if he is able to wait, if he is able to fast. Numerous studies have shown that caloric restriction increases the lifespan and youthfulness of almost all species, starting with fruit flies and ending with rhesus monkeys. In humans, there is no definite anti-aging proof but fastings been shown to improve biomarkers, reduce inflammation, promote stem cell growth, boost the immune system and make you burn a ton of fat. However, the key to successfully gaining these health benefits comes from avoiding malnutrition and starvation. Theres a hugedifference between fasting, starvationand caloric restriction, but it doesn't mean you can't be starving while intermittent fasting or consuming fewer calories. This video tells you how to avoid starvation mode while fasting and gain the longevity benefits More In-Depth video on autophagy: https://www.youtube.com/watch?v=_2kW_... Read the blog post for the referred studies: http://siimland.com/physiology-of-fas... Subscribe for videos on becoming superhuman: https://goo.gl/TSDCuv Keto//IF: HTTP://www.siimland.com/keto-if-fasting/ Stay Empowered Siim Join my Facebook group: https://www.facebook.com/groups/bodym... What is this awesome ring I'm wearing?: https://www.youtube.com/watch?v=399Xt... Use the code SIIMLAND to get -20% from Perfect Keto exogenous ketones: http://bit.ly/2gvn88m #fasting #intermittentfasting #weightloss #fatloss #burnfat #loseweight #losefat #keto Disclaimer I do not own any of the video clips used in this video. The legal rights belong to the legal copyright holders of said content. I have used them under the 'fair use' policy and have done so for entertainment and educational purposes only. Follow me on social media: Blog: http://siimland.com Facebook: https://www.facebook.com/thesiimland/ My Facebook Group: https://www.facebook.com/groups/bodym... Instagram: https://www.instagram.com/siimland/ Twitter: https://twitter.com/inthevanguard Pinterest: https://www.pinterest.com/siimland/ Patreon: https://www.patreon.com/siimland
Starvation-induced True Diabetic Euglycemic Ketoacidosis In Severe Depression
Go to: A 34-year-old man with a 19-year history of type 1 diabetes presented as an emergency with a 4-day history of nausea, vomiting, and flu-like symptoms. He was on a basal bolus insulin regime comprising 8 units of bolus insulin lispro injected at mealtimes and 12 units of basal isophane insulin at bedtime, but did not monitor capillary blood glucose levels. He did however empirically increase his insulin doses during times of illness and had increased his isophane insulin to 15 units during the 3 days prior to presentation. He had only one prior hospital admission, which occurred 6 years previously and was due to an episode of DKA precipitated by gastroenteritis. He was single, unemployed, did not drink alcohol, had no previous psychiatric history, no family history of diabetes or other medical conditions, and lived in a hostel. He had a record of poor clinic attendances and a history of long-term cannabis use. He denied any salicylate consumption, but admitted to some weight loss; however, he was unable to quantify this. His body mass index (BMI) was 19 kg/m2, and he looked unkempt. Physical examination revealed a temperature of 36.4°C (97.5°F), heart rate of 106 beats per
Ketones, ketosis, ketoacidosis, DKA…these are words that you’ve probably heard at one point or another, and you might be wondering what they mean and if you need to worry about them at all, especially if you have diabetes. This week, we’ll explore the mysterious world of ketones, including if and how they may affect you. Ketones — what are they? Ketones are a type of acid that the body can form if there’s not enough carbohydrate to be b ...
Let’s break it down so that you can understand exactly what ketosis is and how it differs from ketoacidosis. But the states they refer to are nothing alike. In this case, maybe mistakes are understandable. Many people who believe that ketosis is dangerous are mixing it up with another state called "ketoacidosis." The two words do sound very similar. And some people simply make mistakes. Profit motives tend to muddy up the works when it comes to ...
"Ketosis" is a word you'll probably see when you're looking for information on diabetes or weight loss. Is it a good thing or a bad thing? That depends. Ketosis is a normal metabolic process, something your body does to keep working. When it doesn't have enough carbohydrates from food for your cells to burn for energy, it burns fat instead. As part of this process, it makes ketones. If you're healthy and eating a balanced diet, your body controls ...
INTRODUCTION Ketoacidosis is the term used for metabolic acidoses associated with an accumulation of ketone bodies. The most common cause of ketoacidosis is diabetic ketoacidosis. Two other causes are fasting ketosis and alcoholic ketoacidosis. Fasting ketosis and alcoholic ketoacidosis will be reviewed here. Issues related to diabetic ketoacidosis are discussed in detail elsewhere. (See "Diabetic ketoacidosis and hyperosmolar hyperglycemic state ...
Acetoacetate, beta-hydroxybutyrate, and acetone are ketone bodies. In carbohydrate-deficient states, fatty-acid metabolism spurs acetoacetate accumulation. The reduction of acetoacetate in the mitochondria results in beta-hydroxybutyrate production. Beta-hydroxybutyrate and acetoacetate, the predominant ketone bodies, are rich in energy. Beta-hydroxybutyrate and acetoacetate transport energy from the liver to other tissues. Acetone forms from the ...