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Role Of Kidneys In Metabolic Acidosis

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Renal Function During Metabolic Acidosis

Department of Animal Physiology and Cytobiology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, Szczecin, Poland Metabolic acidosis influences renal structural and functional changes that occur to restore acid-base homeostasis. In this review selected aspects of these changes are discussed, focusing especially on alternations in tubular reabsorption and excretion, changes in water homeostasis and induction of hypertrophy. Also highlighted is the usage of proteomic techniques and gene expression analysis as useful tools which facilitate the obtaining of a wider view on changes in the kidneys during metabolic acidosis. MSc. in Biology, Department of AnimalPhysiology and Cytobiology, Faculty of Biotechnology and Animal Husbandry,West Pomeranian University of Technology, Doktora Judyma 6, 71-466 Szczecin,Poland. Barthwal MS: Analysis of arterial blood gases a comprehensive approach. J Assoc Physicians India 2004, 52, 573-577. Koeppen BM: Renal regulation of acid-base balance. Advan Physiol Educ 1998, 275, 132-141. Rutkowiak B: Zaburzenia trawienne i metaboliczne w stadach krow mlecznych. PWRiL, Warsaw 1987. Cheval L, Morla L, Elalouf JM, Douce Continue reading >>

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  1. Akron2010

    What is the name of this kidney problem? It was only a very small amount doctors found that is NOT even visible to the eye.
    What does it mean if you:
    . pee blood
    . have a history of high blood pressure
    . you're told by your doctor that you can't eat red meat for the rest of your life or kidneys will get worse.

  2. okgo

    Blood in the urine is known as hematuria. There are a lot of different causes. Kidney stones are a common cause and the tendency to form the more common type of stone is worsened by high protein consumption -- people on the Atkins diet or on ketogenic diets for epilepsy/other conditions often get kidney stones. High-protein diets cause your kidneys to work harder, so avoiding red meat will stress them less if you have chronic kidney disease (CKD) or any other renal problem.
    Consumption of red meat may also be a concern if you have a history of high blood pressure, and high blood pressure can be related to kidney problems. Controlling your high blood pressure will lead to better outcomes if you've got renal problems.
    Without more details I can't say what your diagnosis is; wouldn't they tell you?

  3. cb at sea

    Some folks who have this have no problems at all...it's hereditary....Hubby and son both have this, but no problems have ever been found. Hubby's sister also had it.
    You should get checked thouroughly to make sure there's no problem!

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Current Status Of Bicarbonate In Ckd

Division of Nephrology and Hypertension, Case Western Reserve University, University Hospital Case Medical Center, Cleveland, Ohio Dr. Thomas H. Hostetter, Division of Nephrology and Hypertension, Case Western Reserve University, University Hospital Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106. Email: Thomas.Hostetter{at}uhhospitals.org Metabolic acidosis was one of the earliest complications to be recognized and explained pathologically in patients with CKD. Despite the accumulated evidence of deleterious effects of acidosis, treatment of acidosis has been tested very little, especially with respect to standard clinical outcomes. On the basis of fundamental research and small alkali supplementation trials, correcting metabolic acidosis has a strikingly broad array of potential benefits. This review summarizes the published evidence on the association between serum bicarbonate and clinical outcomes. We discuss the role of alkali supplementation in CKD as it relates to retarding kidney disease progression, improving metabolic and musculoskeletal complications. Patients with CKD experience a multitude of abnormalities and disabilities, among which metabolic acidosis Continue reading >>

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  1. 2Dolls

    Hi there I am new to MagicMum this is my first post.
    We have an adorable little girl aged 3.5yrs, she's had lots of tests over the past 1.5yrs most recently for endocrine which were clear, mitochondria don't have full results but latest skin biopsy was clear, the Drs discovered while in the unit that she has a problem with her blood sugars as she had some hypos in there. We are waiting on results for Glycogen Storage Disease, consultant told us if this one is clear then more than likely we will have to put her blood sugar problems down to Ketotic Hypoglycemia although her symptoms don't fit it. Just wondering if anyone out there has come across KH and how you dealt with it and how your lo is doing. TIA

  2. rosepetal

    Hi 2dolls, my ds1 had ketotic hypoglycaemia from age 18mths to 9yrs, and I have never heard of another child with the same thing til now!!
    My pm function doesnt work for some unfathomable reason so I cant pm you but if you pm me your email address we can chat that way (if you want!) without medical details etc being broadcast to the world

  3. 2Dolls

    Hi rosepetal thanks for the reply have sent you a pm.
    Our little girl is non symptomatic so we need to keep a close eye on her, shes on a high carb/high sugar diet with fasting times. She had ketones in her urine the other morning I just checked it on spec, I know if I ring the unit they will want me to reduce her fasting times, they have told us we could always look at adding corn starch to her meals, did you ever use the corn starch?
    I can't believe you haven't come across anyone else with KH, I thought I would find it easy to find people with experience of it as some support would be great.
    Chat again, 2Dolls.

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Role Of The Kidneys In Maintaining Normal Blood Ph

Role of the kidneys in maintaining normal blood pH Summarized from Hamm L, Nakhoul N, Hering-Smith K. Acid-base homeostasis. Clin J Amer Soc Nephrology 2015; 10: 2232-42 The maintenance of blood pH within normal limits (7.35-7.45), called acid-base homeostasis, is a complex synergy involving three organs (lungs, kidneys and brain) as well as chemical buffers in blood and blood cells (erythrocytes). This vital physiologic process is the subject of a recent expert review article, authored by three academic/research nephrologists that focuses principally, although not exclusively, on the role of the kidney. The article begins with a broad overview of acid-base homeostasis, its pathophysiological importance and some familiar basic concepts such as bicarbonate buffering system and the related Henderson- Hasselbalch equation. The concept of metabolic/respiratory components of acid-base balance allows brief discussion of the integrated role of brain, lungs and kidneys. This introduction paves the way for the central focus of the article, which is the authors research interest: the role of the kidneys in acid-base homeostasis. In broad terms this role has two aspects that both relate to m Continue reading >>

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  1. kristafb

    Just wanted to share with you all. I am not endorsing the site, know nothing about them other than someone on the facebook group posted the link & the price for the box of 50, even with $15 shipping (for canada anyway) is decent.
    http://www.storenvy.com/stores/194693-ketosis-tools

  2. Booksandbeaches

    Thanks!

  3. EddieHaskell97

    I hate them as a company, but Wally-World sells them for $6.84.
    http://www.walmart.com/ip/ReliOn-Ketone-Test-Strips-50-count/33574014

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