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Renal Tubular Acidosis Medscape

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In this video we discuss what is homeostasis and why it is important for health. We also cover what is set point, and cover how homeostasis uses it to keep a stable internal environment. What is homeostasis? To be brief and to the point, homeostasis is the relatively constant state maintained by the body. Mainly this means that over time, the internal body will maintain a stable environment. So, for example, if the external temperature is cold or hot, the internal body temperature will remain relatively constant at 98.6f or 37c, the internal body temp may vary a little above or below this number, but that will still be normal. So, lets say we took someones body temperature over a certain time period. If we plot that on a chart it may look something like this. Here, body temperature rose slightly, and here it fell a little. But, the normal body temperature range is from 97.7 to 99.5. So, our subject was inside the normal range throughout the time span. Homeostasis doesnt just apply to body temperature, but many other conditions as well. The human body needs to maintain a certain range of nutrients in the blood stream, such as water, glucose, salt, and other elements as well. We get

Acid-base Homeostasis: Overview For Infusion Nurses

Acid-Base Homeostasis: Overview for Infusion Nurses September/October 2016, Volume 39 Number 5 , p 288 - 295 This article has an associated Continuing Education component. Expires October 31, 2018. Go to CE Details Acid-base homeostasis is essential to normal function of the human body. Even slight alterations can significantly alter physiologic processes at the tissue and cellular levels. To optimally care for patients, nurses must be able to recognize signs and symptoms that indicate deviations from normal. Nurses who provide infusions to patients-whether in acute care, home care, or infusion center settings-have a responsibility to be able to recognize the laboratory value changes that occur with the imbalance and appreciate the treatment options, including intravenous infusions. D.J., a 24-year-old male, presented to the hospital following a serious motor vehicle collision. He suffered a head injury and multiple internal injuries that required admission to the intensive care unit. D.J. developed acute kidney injury and received rapid-volume resuscitation with 0.9% sodium chloride. In the following days, he experienced multiple seizures requiring intubation for airway protectio Continue reading >>

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  1. Gerald

    I am a type 2 diabetic and I was hospitalized in April for little more then a week with DKA triggered by pneumonia. Since then I have been working hard at recovery including keeping my blood sugar under control with insulin therapy. Even so I seem to have some longer lasting issues and I haven't been able to find are what, if any, typical symptoms of the aftermath of DKA and what a typical recovery pattern is.
    For example, for myself I find the muscles in my legs are very tight, stiff and sore. In particular, if I sit down for awhile and then get up I am basically doing the old man shuffle for five minutes until everything loosens up. I started jogging in May and this has helped quite a bit but I'm wondering if this gets better on it's own or I need to push harder on the exercise?
    In addition to the soreness of legs I'm generally quite lethargic compared to before being hospitalized. I pretty much require a full eight hours sleep a night to be functional at work and I sleep a lot on the weekend to recover enough for the following week of work. I work as software consultant so my work is not physically tiring but is mentally challenging. My wife thinks this is mostly pneumonia not DKA because she remembers it took her about six months to lose the lethargic feeling after she got pneumonia.
    Anyways the above are just examples, what I'm really looking for is an informative link of "typical symptoms while recovering from DKA consist of XXX and typically take YYY to recover". I've googled but been unable to find any references, do people normally make a quick recovery with no lasting issues and I am just unlucky?

  2. notme

    I have not heard of lasting effects from DKA. What have your blood glucose readings been since you were released from the hospital? My concern would be slow onset of DKA if your readings are high.
    Are you taking any statin drugs for high cholesterol? I had serious muscle pain and lethargy as well as depression from taking Lipitor.

  3. Gerald

    Thanks for the response Nancy. I have been averaging about 8 on the glucose readings, it would actually be a bit lower if not for DP. Other then insulin I am not on any other medication though.

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Fanconi syndrome or Fanconi's syndrome (English /fnkoni/, /fn-/) is a syndrome of inadequate reabsorption in the proximal renal tubules of the kidney. The syndrome can be caused by various underlying congenital or acquired diseases, by toxicity (for example, from toxic heavy metals), or by adverse drug reactions Create your own amazing whiteboard videos like this with VideoScribe https://goo.gl/GoGfxW Most important highyield topics, concepts and points are classified and arranged for easy preparation in our YouTube channel. More than hundred videos have been uploaded and we will be adding multiple videos every week. The videos can be accessed free by going to the following link below http://www.youtube.com/user/fmgsindia... All you have to do is subscribe and get notified of the new videos. Every video notes gives you an overview of highyield information about the particular content/topic. Download our android app here https://play.google.com/store/apps/de... Download our ios/iPad app here https://itunes.apple.com/in/app/rewis... ENGAGE Subscribe to our channel: http://www.youtube.com/user/fmgsindia... Leave a comment, thumbs up the video (please!) * learn more :http://www.rewisem

Fanconi Syndrome

Mark H. J. Litzinger, BSc, BSc Pharm, RPh Philadelphia College of Osteopathic MedicineGeorgia Mersedyes D. Boatman, BSc, PharmD Candidate Fanconi syndrome is a disease that is associated with dysfunction of the proximal tubule of the kidney. It is characterized by the wasting of phosphate, amino acids, glucose, and bicarbonate in varying degrees.1 Clinical manifestations stem from direct or indirect disturbances of the tubule system.2 Fanconi in children and adult populations frequently presents with bone diseases as sequelae of the syndrome. Emil Abderhalden first investigated Fanconi syndrome in 1903. Finding cysteine crystals in an infant child, he termed it a familial cystine diathesis.3 Guido Fanconi, a Swiss pediatrician, later gave his contributions to the understanding of the disease when he noted similarities in cases he had encountered. Subjects in these cases presented with dwarfism, hypophosphatemia, and organic acid excretion into the urine.3 Advances in uncovering the mechanisms responsible for this disease continue to elude investigators. Pharmacists in an institutional setting can have a profound impact by familiarizing themselves with the treatment options availab Continue reading >>

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  1. #1 Guest_Valar Morghulis_*

    Hi everyone!
    I'm going to try the ketogenic diet and I'll be posting my intake and progress on this thread.
    I have ordered some ketostix so I can see if I'm in ketosis and it should be here tomorrow.
    I have liquid fasted yesterday (99 cal worth of broth, sugarfree energy drink, and low cal hot cocoa) and I'm starting today with a high fat - moderate protein - low carb diet.
    I'm trying not to go over 700 calories which will be quite scary because I'm used to 300/400 calories or less. Just hoping this will work out!

  2. he shot me down

    following

  3. Ih8carbs

    Me too! But I'm concerned about you so severely calorie restricting with keto...usually best to do one or the other...you might feel HORRIBLE if you restrict both calls/ carbs

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Orphanet: Arthrogryposis Renal Dysfunction Cholestasis Syndrome

The prevalence is unknown but less than 100 patients have been reported in the literature so far. The phenotype is variable, even within the same family and cases may go undiagnosed as not all the patients present with the three cardinal features. Renal tubular dysfunction ranges from isolated renal tubular acidosis to complete Fanconi syndrome (polyuria, aminoaciduria, glycosuria, phosphaturia and bicarbonate wasting). Hepatic anomalies include variable combinations of cholestasis, intrahepatic biliary duct hypoplasia and lipofuscin deposition. Additional features include severe failure to thrive, platelet dysfunction (which may be responsible for severe bleeding), facial dysmorphism (low set ears, lax skin, a high arched palate, beaked nose and small anterior fontanelle), diarrhea, recurrent febrile illness, cerebral malformations and sensorineural deafness. Mutations in the VPS33B gene (15q26.1), involved in intracellular protein trafficking and membrane fusion, have been found in 75% of ARC families, as well as mutations in the VIPAR gene (C14ORF133), encoding a protein that complexes with VPS33B. The differential diagnosis should include progressive familial intrahepatic chol Continue reading >>

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  1. sammerb

    I understand ketosis is achieved when staying between 0-50g of carbs, upwards to 100g for some people.
    But I was wondering where sugar fits in to this?
    The reason I'm asking is there's a full fat greek yogurt that I LOVE. But it's got 15g of carbs and 10g of sugar.
    Will eating that likely to kick me out of ketosis?

  2. Egoldstein

    thinking about being IN ketosis or not is somewhat misleading. What you want is to be fully keto-adapted, meaning your body will seamlessly move from carb burning, fat burning, maybe protein burning back and forth. The carb flu period is when you are not fully adapted and feel a bit out of sorts when transitioning. For someone fully adapted, having a high carb meal or day should not impair longer-term fat burning and fatloss.

  3. OnTheBayou

    Sugar and carbs in yogurt is misleading. Carbs in all foods are not determined directly, but presumed to be what is left over after subtracting proteins and fats. Most, but not all, of the milk's lactose is converted to acids (acidolphilus, any one?) which while still carbs are no longer sugars.
    Just stay away from sugar added yogurts and don't eat it too often. It is dairy.

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