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Physiologic Insulin Resistance Keto

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What is INSULIN RESISTANCE? What does INSULIN RESISTANCE mean? INSULIN RESISTANCE meaning - INSULIN RESISTANCE definition - INSULIN RESISTANCE explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Insulin resistance (IR) is a pathological condition in which cells fail to respond normally to the hormone insulin. The body produces insulin when glucose starts to be released into the bloodstream from the digestion of carbohydrates in the diet. Normally this insulin response triggers glucose being taken into body cells, to be used for energy, and inhibits the body from using fat for energy. The concentration of glucose in the blood decreases as a result, staying within the normal range even when a large amount of carbohydrates is consumed. When the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. This often remains undetected and can contribute to a diagnosis of type 2 diabetes or latent autoimmune diabetes of adults. Although this type of chronic insulin resistance is harmful, during acute illness it is actually a well-evolved protective mechanism. Recent investigations have revealed that insulin resistance helps to conserve the brain's glucose supply by preventing muscles from taking up excessive glucose. Insulin resistance should even be strengthened under harsh metabolic conditions such as pregnancy, during which the expanding fetal brain demands more glucose. People who develop type 2 diabetes usually pass through earlier stages of insulin resistance and prediabetes, although those often go undiagnosed. Insulin resistance is a syndrome (a set of signs and symptoms) resulting from reduced insulin action; it is also part of a larger constellation of symptoms called the metabolic syndrome. Insulin resistance may also develop in patients who have recently experienced abdominal or bariatric procedures. This acute form of insulin resistance that may result post-operatively tends to increase over the short-term with sensitivity to insulin typically returning to patients after about five days.

Physiological Insulin Resistance

I’ve been meaning to do a deep dive into physiological insulin resistance for quite a while now, but the universe keeps conspiring to take my time. Because I haven’t had time to read, learn more and write about it, I thought I’d share the links I have accumulated thus far. Mostly because I’ve now been asked a variant of the following multiple times, or have seen the following posted on various forums for discussing nutrition, health, and low carbohydrate diets: “Why has my blood glucose gone up on a low carb diet?” Typically this is accompanied by a good deal of anxiety and fretting over glucometers. I should know, I watched my blood glucose increase by a few points as I’ve sustained my low carb diet. My understanding is that this is a known adaptation completely unrelated to the insulin resistance concomitant with diabetes. While I’m not the person you should ask about anything health related, I’ve wanted an answer to this question myself. The explanation I’ve read is that after going low carb, your muscle tissue becomes insulin resistant in order to preserve serum glucose availability for the brain. If your muscle tissue did not do this, reduced availability o Continue reading >>

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Popular Questions

  1. BobbyS

    Can insulin resistance truly be reversed?

    I'm a bit unclear on what "insulin resistance reversal" or "diabetes reversal" really means.
    I was diagnosed as prediabetic about 3 weeks ago. I got a blood meter and my first test was postprandial and showed 191.
    I have been water fasting and eating LCHF since then...except for 3 days which is where I get the following info:
    It appears that "real food carbs" (e.g. carrots, onions, etc.) have virtually no effect on me. A meal with ~ 80 grams of real food carbs moved my blood glucose from 83 to 89.
    It also appears that eating LCHF keeps my blood glucose well < 100 but a single sugar/starch/refined flour meal will spike my blood sugar anywhere from 150 to 160 (I've eaten 2 such meals is where I get this data) and it takes a couple of days for my blood sugar to drop back below 100 (at least at my "dawn phenomenon" readings).
    Is "insulin resistance reversal" truly possible or can insulin resistance only be managed as long as sugar/starch/refined is avoided like the plague?
    I know I can't go back to eating like I used to eat...but it would be nice to hope that one day I will be able to "splurge occasionally" and keep normal blood sugar numbers...

  2. qsefthuko

    You might. Some people can some people can't.

  3. qsefthuko

    Apparently LCHF causes a degree of insulin resistance or something. If you have been eating LCHF for a bit and then eat a carby meal it can and probably will raise you higher than you might expect.

  4. -> Continue reading
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2/2011 Full episode: https://robbwolf.com/2011/02/22/the-p... http://high-fat-nutrition.blogspot.co...

Physiological Insulin Resistance

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Hi, I have been doing a little reading on this subject but I`m still not sure if I have a handle on it or not and would like a little advice please. My understanding is as follows: A lot of t2`s have Pathological insulin resistance so that when we produce glucose our pancreas has to produce insulin but we don`t use it very well which means more insulin which causes weight gain and so on... A low carb diet produces less glucose which calls for less insulin which has to be a good thing presumably. However, carb restriction can also cause Physiological insulin resistance which, if I understand correctly, saves the smaller amount of glucose which is produced for the brain by making the muscles insulin resistant which leads to higher bg readings. Is my understanding anywhere close to correct and will these higher bg levels lead to a higher HBA1C ? Thank you for reading and please reply with your opinions. Chris. Hi, I have been doing a little reading on this subject but I`m still not sure if I have a handle on it or not and would like a little advice please. My unders Continue reading >>

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Popular Questions

  1. BobbyS

    Can insulin resistance truly be reversed?

    I'm a bit unclear on what "insulin resistance reversal" or "diabetes reversal" really means.
    I was diagnosed as prediabetic about 3 weeks ago. I got a blood meter and my first test was postprandial and showed 191.
    I have been water fasting and eating LCHF since then...except for 3 days which is where I get the following info:
    It appears that "real food carbs" (e.g. carrots, onions, etc.) have virtually no effect on me. A meal with ~ 80 grams of real food carbs moved my blood glucose from 83 to 89.
    It also appears that eating LCHF keeps my blood glucose well < 100 but a single sugar/starch/refined flour meal will spike my blood sugar anywhere from 150 to 160 (I've eaten 2 such meals is where I get this data) and it takes a couple of days for my blood sugar to drop back below 100 (at least at my "dawn phenomenon" readings).
    Is "insulin resistance reversal" truly possible or can insulin resistance only be managed as long as sugar/starch/refined is avoided like the plague?
    I know I can't go back to eating like I used to eat...but it would be nice to hope that one day I will be able to "splurge occasionally" and keep normal blood sugar numbers...

  2. qsefthuko

    You might. Some people can some people can't.

  3. qsefthuko

    Apparently LCHF causes a degree of insulin resistance or something. If you have been eating LCHF for a bit and then eat a carby meal it can and probably will raise you higher than you might expect.

  4. -> Continue reading
read more
Share on facebook

Low Carb High Fat Diet or High Carb Diet - Which Causes Insulin Resistance: https://youtu.be/NbU8RIBRvjI Diabetes: https://www.youtube.com/playlist?list... -------------------------------------------------------------------------------------- Mentioned Book - Video - Website / Shout Outs -------------------------------------------------------------------------------------- DR GREGER'S BOOK - HOW NOT TO DIE US Amazon Book How Not to Die: http://amzn.to/2g67bmK UK Amazon Book How Not to Die: http://amzn.to/2grlYwy http://nutritionfacts.org/book/ Dr Greger's YouTube Channel https://www.youtube.com/user/Nutritio... Dr Gregers website http://nutritionfacts.org/ This is for educational purposes only and no copyright infringement is intended. ===================================================== Thanx for watching this Video!! Please do SUBSCRIBE & LIKE so you can help my new channel to GROW! & share this with friends All your support means the world to me! Till next time Keep on Keepin On & Just Go Do It Already ===================================================== STATS Name: Jon Anthony Age: 45 Height: 6:3" / 191cm Starting Weight: 151.8kg / 335lbs / (BMI) 41.9 Current Weight: 111.0kg / 244lbs / (BMI) 30.6 To date Loss Weight: 40.8kg / 89.76lbs / 6 stones Goal Weight: is to lose another 20kg - 44lbs And then to see what it looks like when I get there :) 90kg / 198lbs (BMI) 24.7 KG to LBS: http://kgtolbs.net https://www.google.co.uk/search?q=kg%... =============================================== BUSINESS Inquiries: [email protected] =============================================== Michael Greger MD NGO Website: http://nutritionfacts.org Book How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease US Amazon Book How Not to Die: http://amzn.to/2g67bmK UK Amazon Book How Not to Die: http://amzn.to/2grlYwy Your purchase or the Book How Not to Die via the link above will have money go to the NGO http://nutritionfacts.org and very small affiliate commission will be sent to me. =================================================== Visualize What Losing 10kg / 22lbs Looks Like https://youtu.be/JjrsD4erTXg I have lost well over 85+ lbs to date January 23rd 2017 - 109.8kg / 241.5lbs - Went Gym January 22nd 2017 - 109.8kg / 241.5lbs - Went Gym January 21st 2017 - 110.2kg / 242.4lbs - Went Gym January 20th 2017 - 110.5kg / 243.1lbs - Went Gym January 19th 2017 - 110.8kg / 243.7lbs - Went Gym January 18th 2017 - 110.8kg / 243.7lbs - Went Gym January 17th 2017 - 110.7kg / 243.5lbs - No Gym January 16th 2017 - 110.7kg / 243.5lbs - Went Gym January 15th 2017 - 111.8kg / 244.8lbs - Went Gym January 14th 2017 - 111.3kg / 244.8lbs - No Gym January 13th 2017 - 111.9kg / 246.1lbs - Went Gym January 12th 2017 - 111.8kg / 245.9lbs - Went Gym January 11th 2017 - 112.4kg / 247.2lbs - Went Gym January 10th 2017 - 112.2kg / 246.8lbs - Went Gym

A High-fat, Ketogenic Diet Causes Hepatic Insulin Resistance In Mice, Despite Increasing Energy Expenditure And Preventing Weight Gain

Go to: Low-carbohydrate, high-fat ketogenic diets (KD) have been suggested to be more effective in promoting weight loss than conventional caloric restriction, whereas their effect on hepatic glucose and lipid metabolism and the mechanisms by which they may promote weight loss remain controversial. The aim of this study was to explore the role of KD on liver and muscle insulin sensitivity, hepatic lipid metabolism, energy expenditure, and food intake. Using hyperinsulinemic-euglycemic clamps, we studied insulin action in mice fed a KD or regular chow (RC). Body composition was assessed by 1H magnetic resonance spectroscopy. Despite being 15% lighter (P < 0.001) than RC-fed mice because of a 17% increase in energy expenditure (P < 0.001), KD-fed mice manifested severe hepatic insulin resistance, as reflected by decreased suppression (0% vs. 100% in RC-fed mice, P < 0.01) of endogenous glucose production during the clamp. Hepatic insulin resistance could be attributed to a 350% increase in hepatic diacylglycerol content (P < 0.001), resulting in increased activation of PKCε (P < 0.05) and decreased insulin receptor substrate-2 tyrosine phosphorylation (P < 0.01). Food intake was 56% Continue reading >>

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Popular Questions

  1. BobbyS

    Can insulin resistance truly be reversed?

    I'm a bit unclear on what "insulin resistance reversal" or "diabetes reversal" really means.
    I was diagnosed as prediabetic about 3 weeks ago. I got a blood meter and my first test was postprandial and showed 191.
    I have been water fasting and eating LCHF since then...except for 3 days which is where I get the following info:
    It appears that "real food carbs" (e.g. carrots, onions, etc.) have virtually no effect on me. A meal with ~ 80 grams of real food carbs moved my blood glucose from 83 to 89.
    It also appears that eating LCHF keeps my blood glucose well < 100 but a single sugar/starch/refined flour meal will spike my blood sugar anywhere from 150 to 160 (I've eaten 2 such meals is where I get this data) and it takes a couple of days for my blood sugar to drop back below 100 (at least at my "dawn phenomenon" readings).
    Is "insulin resistance reversal" truly possible or can insulin resistance only be managed as long as sugar/starch/refined is avoided like the plague?
    I know I can't go back to eating like I used to eat...but it would be nice to hope that one day I will be able to "splurge occasionally" and keep normal blood sugar numbers...

  2. qsefthuko

    You might. Some people can some people can't.

  3. qsefthuko

    Apparently LCHF causes a degree of insulin resistance or something. If you have been eating LCHF for a bit and then eat a carby meal it can and probably will raise you higher than you might expect.

  4. -> Continue reading
read more

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