Pathophysiology Of Diabetic Ketoacidosis

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Diabetic Ketoacidosis

Diabetic ketoacidosis (DKA) is defined by the biochemical triad of ketonaemia, hyperglycaemia and acidaemia (1). DKA may result from: absolute deficiency of circulating insulin e.g. - previously undiagnosed type 1 diabetes mellitus patients who do not take insulin deliberately or inadvertently (especially the long acting component of a basal-bolus regimen) relative deficiency caused by increased levels of the counter regulatory hormones: catecholamines, glucagon, cortisol and growth hormone as a response to tress in conditions such as sepsis, trauma, or gastrointestinal illness with diarrhea and vomiting etc. despite taking the usual recommended dose of insulin (2) DKA is thought to be indicative, or even diagnostic, of type 1 diabetes, but increasingly there are cases of ketone-prone type 2 diabetes being recognised (3). patients with type 2 diabetes who have ketosis-prone diabetes represents 20 to 50 % of persons with DKA (these patients have impaired insulin secretion) It should be regarded a medical emergency; its rapid recognition and accurate treatment are essential to prevent morbidity and mortality. It should be noted that there are subtle differences in the management in c Continue reading >>

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Popular Questions

  1. health care and lifestyle

    The A1C is a blood test that shows how well your diabetes management plan is working. Here's how to reach a healthy A1C number and avoid diabetes complications.
    Taking the A1C Test
    If your diabetes is well controlled and your blood sugar levels have remained stable, the American Diabetes Association recommends that you have the A1C test two times each year. A1C test results provide insight into how your treatment plan is working or might be modified to better control the condition. Your doctor may want to run the test as often as every three months if your A1C is not within your target range.

  2. MrsCDogg

    Try some nuts for your protein too. If you are having tofu as your main source of protein then you are having some carbs. All vegetables have carbs. It's just a matter of choosing the right ones that won't raise your blood sugars. Nuts are a great source of protein, fiber and some of them are loaded with the good omega oils too. Good luck with your battle to lower your A1c.

  3. cottoncandybaby

    Veggies that have carbs would be the starchy kind like peas, corn, of course potatoes. I eat a lot of broccoli, green beans, zucchini, even half of a sweet potato, to add variety. I think the diabetic diet is a lot like the old Adkins diet, which I used to do to lose weight. High protien, low carb. For a treat, I have sugar free jello with whipped cream on top, almost no carbs at all and satisfies my sweet cravings. I have eggs for breakfast, several mornings a week, but don't want to overdo them, so I do have cereal once or twice a week, usually Special K with strawberries or plain cheerios, with low fat milk.

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