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Nutritional Ketosis Blood Glucose Levels

5 Ways To Measure Your Ketones

5 Ways To Measure Your Ketones

5 Ways to Measure Your Ketones A ketogenic diet is a very low carbohydrate, moderate protein and high fat based nutrition plan. A ketogenic diet trains the individual’s metabolism to run off of fatty acids or ketone bodies. This is called fat adapted, when the body has adapted to run off of fatty acids/ketones at rest. Research has demonstrated that this nutrition plan improves insulin sensitivity and reduces inflammation throughout the body. This leads to greater fat metabolism and muscle development as well as a reduced risk of chronic disease. (1, 2). I get asked all the time how to measure the state of ketosis. There are several major ways and we will discuss those in this article. Measuring Your Ketones There are three types of ketone bodies: Acetone, Acetoacetate and Beta-Hydroxybutryate (BHB). Each of these three can be tested as acetone is a ketone released through the breath, acetoacetate is a ketone released through urine and BHB is (although not technically a ketone it acts like a ketone) in the blood stream and used by the cells for energy. 1. Blood Ketone Meter This measures BHB and is considered to be the most accurate way to measure ketone bodies. These have the ability to determine the ketone level in your blood precisely but they are also pricey and invasive. Personally, I freak out every time I have to prick my finger!! The Precision Xtra blood glucose and ketone meter is a good buy at $28-$30. The expensive part is the ketone test strips here which can cost $4 each. If you are looking at testing yourself every day it is going to cost you $120 a month and the $30 meter. Here is a starter kit you can get on Amazon Most people will enter into a light nutritional ketosis (between 0.5-1.0 mmol/L on the meter) within two or three days. It typically takes Continue reading >>

Actions That Increase And Decrease Ketones

Actions That Increase And Decrease Ketones

In this article, i compiled a list of things that increased and decreased my blood ketone level (beta-hydroxybutyrate). What we’re after is a strong ketone level (between 0.5-3.0mmol/l) paired with low blood glucose (3.0-3.5mmol/l). When these numbers have been obtained, it’s likely a sign that blood sugar is regulated, insulin isn’t pumping through the blood as crazily as in most people, and the walls of our fat cells are wide open, ready for lipolysis to work its magic. If you’re finding that your journey to nutritional ketosis hasn’t been as “easy” as what you’ve read in my blog, this is a great article to getting some insight on what could be happening. You’re likely missing something; a small something, that’s limiting your body’s ability to switch into ketosis. If this is you, take a read through this list to see if there are glaring issues with your current approach. I have made; and continue to make, slip ups that affect my ketone levels. The great thing about it all is that the further I’ve gone, the more forgiving my body is. It is quite astounding how adapted my body has become. It WANTS to be in nutritional ketosis and will bounce back quite effortlessly. Find out more on Top Ketogenic Diet Ebook with Online Diet Generator Tool. To download the ebook please Click Here. MCT Oil Medium-chain-triglycerides the rocket fuel for nutritional ketosis. Starting my day with 1-2 tablespoons of this stuff blended with my coffee boosts my ketone level to soaring heights. Quick Tip: Because MCT oil is used directly as fuel; especially for the brain, it’s best to start off slow with 1 teaspoon and work your way up. Too fast, and you may experience digestive upset. Balancing Intake I’ve learned that my body responds best when I consume 1-2 meals Continue reading >>

What Is A Glucose Ketone Index And Why You Should Care

What Is A Glucose Ketone Index And Why You Should Care

Having high levels of ketones doesn’t mean you’re automatically getting all of the benefits. Luckily, research shows us that there’s an easy way to know if you’re in prime therapeutic mode so you can be confident you’re getting the best results. Ketosis can already be complicated if you don’t test and figure out what kicks you out. Once you start getting serious about ketosis and tracking ketone levels, you can usually step things up a notch with a simple calculation. You can become more specific with what works for you as an individual. How you do that is by calculating your glucose ketone index. The Glucose Ketone Index, or the GKI, is a ratio that researcher Dr. Thomas Seyfried has been using in his studies relating to both fasting and the ketogenic diet. There’s nothing fancy to this index, it is just a ratio of blood glucose levels to blood ketone levels. Having high level of ketones are great and all, but if you also have a super high level of blood glucose, you’re really just spinning your wheels and not getting any benefits of ketosis. And the real key here is to make sure that the ratio between glucose and ketone levels is as low as possible. If you’ve been following along, you’ll note I was pretty big on this glucose ketone index on my recent my four day fast and it actually dictated the time spent in the fast. But why did I care about this ratio, and why should you care? Why Should You Care? Dr. Seyfried does a lot of his research in the realm of cancer treatment and has noticed increasingly impressive therapeutic outcomes with the lower the glucose ketone index ratio gets. Dr. Seyfried claims that a GKI of lower than 1.0 is prime therapy for patients with cancer, and he has plenty of data to back this up. The graph above shows how tumor g Continue reading >>

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

The Glucose Ketone Index Calculator: A Simple Tool To Monitor Therapeutic Efficacy For Metabolic Management Of Brain Cancer

Go to: Abstract Background Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic fermentation of glucose (Warburg effect), which is the common metabolic malady of most cancers including brain tumors. The KD targets tumor energy metabolism by lowering blood glucose and elevating blood ketones (β-hydroxybutyrate). Brain tumor cells, unlike normal brain cells, cannot use ketone bodies effectively for energy when glucose becomes limiting. Although plasma levels of glucose and ketone bodies have been used separately to predict the therapeutic success of metabolic therapy, daily glucose levels can fluctuate widely in brain cancer patients. This can create difficulty in linking changes in blood glucose and ketones to efficacy of metabolic therapy. A program was developed (Glucose Ketone Index Calculator, GKIC) that tracks the ratio of blood glucose to ketones as a single value. We have termed this ratio the Glucose Ketone Index (GKI). The GKIC was used to compute the GKI for data published on blood glucose and ketone levels in humans and mice with brain tumors. The results showed a clear relationship between the GKI and therapeutic efficacy using ketogenic diets and calorie restriction. The GKIC is a simple tool that can help monitor the efficacy of metabolic therapy in preclinical animal models and in clinical trials for malignant brain cancer and possibly other cancers that express aerobic fermentation. Electronic supplementary material The online version of this article (doi:10.1186/s12986-015-0009-2) contains supplementary material, which is available to authorized users. Keywords: Glucose, Beta-hydroxybutyrate, Calorie Continue reading >>

High Blood Sugar In Ketogenic Dieters! Plus A Special Surprise (hint: Genotypes And Metabolism)!

High Blood Sugar In Ketogenic Dieters! Plus A Special Surprise (hint: Genotypes And Metabolism)!

A while ago Michael and I were discussing future article topics. There are truly a plethora of avenues to go down in this area of research and there is no lack of things to research and comment on. But even though I have a couple of pretty cool MCT articles sitting around on my desk, I want an interesting topic. I want something new. Something challenging. Besides, everyone is drinking the MCT koolaid these days. It’s become passe. (Also, it upsets my stomach and I have a personal vendetta against it. So there.) What’s new? There has to be something new! Michael pointed me to one of his old articles on physiological insulin resistance as an idea. I brushed it off at first. Dismissed it as a quirk. But then I thought about it. WHY does blood glucose rise in response to a low carb diet? It truly is an interesting question. What does it say about low carb diets if they induce an almost diabetic effect on circulating glucose? Thus my research began. This short abstract confirmed that it is normal for people on low carb diets to experience a rise in blood glucose levels. Because it’s a non-open journal (shame!), there’s a one-sentence explanation given: A decrease in first-phase insulin secretion may partially contribute to the short-term LC/HFD-induced increase in postprandial plasma glucose levels. First phase insulin secretion? There’s a first phase? So… There’s more than one phase to insulin secretion? I had no idea. Call me ignorant but I had no idea until this point that there was more than one phase to insulin secretion. This article delves deeper into the signaling involved in (what I learned is called) biphasic insulin secretion. The first phase of insulin secretion lasts approximately 10 minutes, and the second phase of insulin secretion picks up afte Continue reading >>

Ketosis & Measuring Ketones

Ketosis & Measuring Ketones

Generally, ketone concentrations are lower in the morning and higher in the evening. Whatever time you pick to measure ketone levels, make sure to keep it consistent. Also, do not measure your ketone levels right after exercise. Ketone levels tend to be lower while your glucose levels higher so you won't get representative numbers. Keep in mind there are daily fluctuations caused by changes in hormone levels. Don't get discouraged! Another aspect that affects the level of ketones is the amount of fat in your diet. Some of you may show higher concentration of ketones after a high-fat meal. Coconut oil contains MCTs that will help you boost ketones. To easily increase your fat intake on a ketogenic diet, try fat bombs - snacks with at least 80% fat content. Ketone levels tend to be higher after extensive aerobic exercise as your body depletes glycogen stores. Exercise may help you get into ketosis faster. ketogenic "fruity" breath is not pleasant for most people. To avoid this, drink a lot of water, mint tea and make sure you eat foods rich in electrolytes. Avoid too many chewing gums and mints, as it may put you out of ketosis; there may be hidden carbs affecting your blood sugar. Increase your electrolyte intake, especially potassium. You are likely going to lose some sodium and potassium when switching to the keto diet. Finally, if you find it hard to lose weight on a ketogenic diet, there may be plenty other reasons than the level of ketone bodies: Not Losing Weight on Low-Carb Ketogenic Diet? Don’t Give Up and Read Further. Continue reading >>

Estimating Blood Ketone Levels From Blood Glucose Readings

Estimating Blood Ketone Levels From Blood Glucose Readings

Ok so the doctor suspects my aunt has a lymphoma, which is a type of cancer. I would like her to get into a state of nutritional ketosis so she can get rid of it through autophagy and by starving the cancerous cells of sugar. I had planned to make her measure her blood ketone levels so I can monitor her progress and modify her diet when necessary, especially because I won't be seeing her everyday and I need a way to make sure she's doing the diet right. Unfortunately I'm on a low budget, and I can't afford too many ketone test strips (she will be using Precision Xtra). The BG strips, on the other hand, are a lot cheaper. So I had this idea of only measuring her blood glucose levels. If the blood glucose level gets below normal range, that means ketone bodies are doing the job of supplying the rest of her energy, right? Then the fasting ketone level must be somehow inversely proportional to the fasting sugar level. For example if the glucose meter reads 50mg I can be sure she's in ketosis(if she doesn't show symptoms of hypoglycemia that is). At the same time, I would like to get the actual numbers for ketones. Our plan is to get her to around at least 2.0 mmol consistently. So this was a lengthy post, here's my question: Is there a formula to estimate ketone levels from just knowing the blood glucose level? What were your own BK and BG levels both at one given time while on keto? edit/ Thank you for those who answered so far :) Yes, I am aware that ketosis is not the solution for all diseases and all types of cancer. But I have seen observational studies suggesting that fasting for 140 hours before and after a chemotherapy diminishes its side effects such a nausea and fatigue, and can also raise the chance of survival. Keto is kind of a "fake starvation" so I thought it Continue reading >>

Blood Sugar Levels In Ketosis: Part Ii

Blood Sugar Levels In Ketosis: Part Ii

Welcome to Keto Sister. Last week’s post explained what happens to blood glucose levels as a result of eating a ketogenic diet. In sum, blood glucose (also known as blood sugar) decreases and is replaced in large part by a new fuel source, ketone bodies. Humans are always being fueled by two energy substrates: glucose and fatty acids. A person who eats a high carbohydrate diet burns more glucose as fuel, and a person who eats a high fat diet burns more fat as fuel. However, there is never a time at which a person stops burning one or the other. The implication for someone eating a low carb diet is that the body never replaces all glucose utilization with ketone bodies. Instead, the body reduces its glucose needs to the bare minimum and then it makes any needed glucose not taken in through the diet through gluconeogenesis. This is the normal, healthy process of fueling the body in the absence of dietary glucose. Elevated Blood Glucose There are many benefits of ketogenic nutrition when a ketogenic diet is implemented correctly. One of the benefits of eating low carb is blood glucose control, and this can be a big benefit to those who struggle with type 2 diabetes and obesity. As I mentioned last week, ideal blood glucose levels are between 81 and 109 milligrams per deciliter (see this post for details). However, it is a common occurrence for those following a very low carb diet to have elevated blood glucose levels. I mentioned the first two causes last week, but there is a third that is rarely discussed by those in the low carb arena. Admittedly, these concepts are not well understood by most people. Nevertheless, here is what we know about elevated blood sugar levels in ketosis: Physiological Insulin Resistance (PhIR). Eating a low carb diet in and of itself can indu Continue reading >>

Lose Weight By Achieving Optimal Ketosis

Lose Weight By Achieving Optimal Ketosis

Do you want to lose weight? Here’s number 16 of my 18 best tips. All of the published tips can be found on the How to Lose Weight page. Before we get started, here’s a short recap of the tips so far: The first and most crucial piece of advice was to choose a low-carb diet. The next were eating when hungry, eating real food, eating only when hungry, measuring progress wisely, being persistent, avoiding fruit, beer and artificial sweeteners, review your medications, stressing less and sleeping more, eating less dairy and nut products, stocking up on vitamins and minerals, using intermittent fasting and finally, exercising smart. This is number sixteen: 16. Get into optimal ketosis Warning: Not recommended for type 1 diabetics, see below. We’ve now arrived at tip number 16. If you’re still having trouble losing weight, despite following the 15 pieces of advice listed above, it might be a good idea to bring out the heavy artillery: optimal ketosis. Many people stalling at weight plateaus while on a low carb diet have found optimal ketosis helpful. It’s what can melt the fat off once again. So how does this work? A quick run-through: The first tip was to eat low carb. This is because a low-carb diet lowers your levels of the fat-storing hormone insulin, allowing your fat deposits to shrink and release their stored energy. This tends to cause you to want to consume less calories than you expend – without hunger – and lose weight. Several of the tips mentioned above are about fine-tuning your diet to better this effect. Video course Do you know exactly how to eat a low-carb and high fat diet (LCHF)? This is required for ketosis. If not the easiest way is watching this high quality 11-minute video course on how to eat LCHF, and the most important things to think a Continue reading >>

Video: What Eating “high-fat” Or “keto” Does To Your Blood Sugar

Video: What Eating “high-fat” Or “keto” Does To Your Blood Sugar

What happens to your blood sugar when you eat fat? The steps you need to stabilize your blood sugar and increase your fat-burning hormones (by following a Fat Fueled, keto eating style). Up until I found keto (high-fat, low-carb living) I was in the “eat every 2-3 hours in order to control blood sugar” camp. What I didn’t know, was that the constant eating; generally of carbohydrates, was exactly what was causing my blood sugar irregularities – constant “hangry” feelings, hypoglycemia, insulin resistance, and more. After a couple of weeks of eating Fat Fueled, keto, I no longer struggled with hypoglycemia. It was as if my sugar lows just… disappeared. And I’m not the only one that’s experienced massive changes to blood sugar shortly after shifting to a Fat Fueled, keto life. I invited Dietitian Cassie on the show today to help explain exactly what happens to our blood sugar when we eat fat – the ins and outs of insulin resistance, actions that affect blood sugar, how to use carb-ups to heal insulin resistance and much more. Today’s keto video encourages us to use dietary fat as our ally, to rely on it to support balanced blood sugar, thriving hormones and a healthy body. For video transcription, scroll down. Highlights… What foods affect blood sugar How dietary fat affects your blood sugar If combining carbohydrates and fat is a good thing How fat cells are created How to get into fat-burning mode Signs and symptoms of insulin resistance and insulin sensitivity How cortisol (and a poor sleep) affects your blood sugar How carb cycling and carb refeeding can help bust through insulin resistance How to heal yourself from insulin resistance Resources… Watch the video: When to know it’s time to carb-up (and how to do it) Step-by-step guide on goin Continue reading >>

Gluconeogenesis

Gluconeogenesis

Gluconeogenesis (GNG) is a metabolic process of making glucose, a necessary body fuel, from non-carbohydrate sources such as protein (amino acids), lactate from the muscles and the glycerol component of fatty acids. Blood glucose levels must be maintained within a narrow range for good health. If blood sugar is too high, it results in tissue and organ damage. If it is too low, cellular respiration and energy production can suffer, especially if the body is "carbohydrate-adapted," meaning the body uses glucose as it's primary fuel. Therefore, the ability of the liver and kidneys to “make new sugar” and regulate blood sugar levels is critical. The main advantage of this process is that it helps the body maintain steady blood sugar levels when foods containing carbohydrates or stored sugars (glycogen reserves) are unavailable. Without gluconeogenesis, you wouldn't live very long, especially without food, as your body must have a constant and steady level of blood glucose to keep the brain and red blood cells going. Mold Test Kits Easy to Use, Fast Results Available Interpretive Lab Report moldtesting.com Glucose and Ignorance If you decide to stop eating, or you decide to follow a low carb ketogenic diet, carbohydrate intake drops. To make up for the missing carbohydrate in your diet, the liver creates the blood glucose it needs by breaking down the glycogen stored in your muscles and liver from your last meal. This process is called glycogenolysis. After about 30 hours with no food, a great deal of this stored glycogen is broken down, and the body must then begin making glucose by breaking down stored fatty acids or amino acids from the protein in your muscles. Some dietitians and trainers insist that this process is the reason that carbohydrates are "essential foods" Continue reading >>

Ketogenic Diet Improves Insulin Sensitivity And Numerous Aging Markers

Ketogenic Diet Improves Insulin Sensitivity And Numerous Aging Markers

A physician conducted a decade-long experiment on the health effects of a ketogenic diet, using himself as the laboratory rat; he experienced improvement in insulin sensitivity, body fat, lipids, blood sugar, and other markers A ketogenic diet requires carbohydrate and protein restriction, with 50 to 80 percent of calories coming from fats; this forces your body to shift toward using ketones as its primary fuel source, instead of glucose Although your brain is more dependent on glucose than your heart, your liver can produce a ketone-like compound that your brain can efficiently use for energy Scientists extended the lifespan of mice by 20 percent by suppressing the activity of just one gene that helps control metabolism and energy balance; this is further evidence that longevity is tied to insulin signaling The best way to jumpstart your fat-burning/ketone-producing engine is by drastically reducing your consumption of sugar and grains, fasting intermittently, and maintaining a consistent exercise routine By Dr. Mercola We are just beginning to understand the biological intricacies of aging. A growing body of research is challenging the belief that aging is beyond your control, prompting scientists to begin thinking about ways we can slow our aging clocks to a slow crawl. Although this is a relatively new branch of science, there are some factors that appear to be key in controlling how quickly you age. One major factor seems to be insulin signaling and the metabolic "engines" you have running day to day, which are largely controlled by the foods you eat. In the first featured video, Dr. Peter Attia discusses how a ketogenic diet can optimize your metabolism. But before I discuss the specifics of this, I want to tell you about a remarkable mouse study, presented in the Continue reading >>

Doing Keto? Consider Buying A Blood Glucose Meter

Doing Keto? Consider Buying A Blood Glucose Meter

The amount of glucose in your blood at any given time can give you valuable insights into how your body is reacting to the food you eat. If you’re doing a keto-based diet, the data you get from a glucose meter will help you optimize your eating for maximum weight loss! The premise of a keto-based diet is simple: Keep the carbs as low as possible so that your body is forced to get glucose (energy) from fat, rather than carbs. Any sort of glycemic reaction could cause a weight-loss stall for several days. Not sure what a Keto diet is, or want to learn more about it? I talk about what a keto diet is, and the pros and cons of this approach, in this blog article. What is a glycemic reaction? In short, a glycemic reaction is what happens when you eat carbs. It’s a fancy name for an even fancier process. Effectively, when you eat carbs, your body produces a hormone called “insulin” which is responsible for delivering the glucose (the energy from your the carbs you just ate) to the muscle cells in your body. In a keto-based diet, you want to avoid the production of insulin at all costs. Not because insulin itself is bad — but because it means you’ve short-circuited the keto process by eating too many carbs, and allowing your body to get energy from carbs, rather than fat. If this happens, it can take days to “reset” your body back into ketosis. In short, if you are doing a keto-based diet and your blood-glucose levels spike, you screwed up. How to measure your blood glucose level Get yourself a blood-glucose meter!! You can buy a blood-glucose meter from any pharmacy in the $20 to $40 range. The test-strips come in packs of 100 for around $25. (around $0.25 each if you’re bad at math). Here’s a link on Amazon to a glucose meter kit that’s perfectly adequat Continue reading >>

How To Measure Ketones And Optimize Ketogenic Diets

How To Measure Ketones And Optimize Ketogenic Diets

The problem with diets is that we think that one diet should be good for everyone. But research and N=1 experiments show that’s not the case. Learn about measuring ketones and ketosis to understand how your low carb or high fat diet is really affecting you. If there is one area of our bodies that is debated to extremes, with literally hundreds of differing strong opinions on it, it’s nutrition. For many, beliefs about nutrition and diet are tribal. We put ourselves in different camps and we war agains the other camps. Whether it be paleo, low fat, low carb, Atkins, high fat, low protein, vegan, raw vegan and so on. It’s exactly this sort of area where I see data as essential. Without data we have no hope of cutting through the maze of opinions to get to what really works. Part of the problem with nutrition and diets is that we tend to think that one diet should be good for everyone. But increasingly, research and N=1 experiments, are showing that that isn’t the case. And this is exactly why you should pay attention to today’s show. Today, we’re looking at what has relatively recently become the fastest growing nutrition or diet trend. The high fat diet. Also known in different guises as the ketogenic diet, or the low carb diet. And specifically how this can affect our different individual biochemistries, how we can measure “Ketosis” and other biomarkers to understand how our specific biology is reacting to it… and allowing us to troubleshoot and course correct when it isn’t getting the desired results we’re looking for from it. Today’s guest is Jimmy Moore. In 2004, Jimmy, at 32 years, weighed 410 pounds. Since then he has transformed his own biology, shedding all that additional weight with low carb and ketogenic diets. He has also interviewed n Continue reading >>

Jimmy Moore’s N=1 Experiments: Nutritional Ketosis Day 1-30

Jimmy Moore’s N=1 Experiments: Nutritional Ketosis Day 1-30

Before I went on the 2012 Low-Carb Cruise last month, I started reading a book that my low-carb research friends Dr. Jeff Volek and Dr. Steve Phinney had written as a follow-up to their fantastic 2011 release The Art And Science of Low Carbohydrate Living (listen to my interview with Dr. Phinney about this book in Episode 479 of “The Livin’ La Vida Low-Carb Show”). The sequel is called The Art And Science Of Low Carbohydrate Performance and was written specifically to share the latest science behind ketogenic diets for athletes who are keenly interested in optimizing their exercise performance with fat and ketones serving as their body’s primary fuel source once they reach what Dr. Phinney refers to as “keto-adaptation.” But the information these low-carb stalwarts provide in this handy dandy little book goes much deeper than that as you will read about in this blog post. Most low-carbers have traditionally been using urine ketone sticks under the brand name Ketostix to measure their level of ketones being produced by color (from pink to dark purple) as a result of their low-carb diet. But as I previously shared in this YouTube video, this can be a frustratingly inaccurate way of measuring whether you are producing enough ketones in your blood to see the kind of results you are hoping for on your low-carb lifestyle change. But thanks to the cutting-edge information provided by Volek and Phinney in The Art And Science Of Low Carbohydrate Performance, we now have a new and better way to measure the actual ketones that are in your blood which determines whether you have become keto-adapted and burning fat and ketones for fuel. They refer to getting into this state as “nutritional ketosis” to obviously distinguish it from ketoacidosis which is only an issue Continue reading >>

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