Normal Anion Gap Metabolic Acidosis Wiki

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Ever wondered what on earth the Anion Gap was all about? Yeah us neither. But when you've got yourself a metabolic acidosis, this is a good place to start. If you liked this, why not subscribe? And more importantly, let us know what you'd like to see us cover next.

Anion Gap

Pathophysiology sample values BMP/ELECTROLYTES: Na+ = 140 Cl− = 100 BUN = 20 / Glu = 150 K+ = 4 CO2 = 22 PCr = 1.0 \ ARTERIAL BLOOD GAS: HCO3− = 24 paCO2 = 40 paO2 = 95 pH = 7.40 ALVEOLAR GAS: pACO2 = 36 pAO2 = 105 A-a g = 10 OTHER: Ca = 9.5 Mg2+ = 2.0 PO4 = 1 CK = 55 BE = −0.36 AG = 16 SERUM OSMOLARITY/RENAL: PMO = 300 PCO = 295 POG = 5 BUN:Cr = 20 URINALYSIS: UNa+ = 80 UCl− = 100 UAG = 5 FENa = 0.95 UK+ = 25 USG = 1.01 UCr = 60 UO = 800 PROTEIN/GI/LIVER FUNCTION TESTS: LDH = 100 TP = 7.6 AST = 25 TBIL = 0.7 ALP = 71 Alb = 4.0 ALT = 40 BC = 0.5 AST/ALT = 0.6 BU = 0.2 AF alb = 3.0 SAAG = 1.0 SOG = 60 CSF: CSF alb = 30 CSF glu = 60 CSF/S alb = 7.5 CSF/S glu = 0.4 The anion gap[1][2] (AG or AGAP) is a value calculated from the results of multiple individual medical lab tests. It may be reported with the results of an Electrolyte Panel, which is often performed as part of a Comprehensive Metabolic Panel.[3] The anion gap is the difference between the measured cations (positively charged ions) and the measured anions (negatively charged ions) in serum, plasma, or urine. The magnitude of this difference (i.e., "gap") in the serum is often calculated in medicine when attempting t Continue reading >>

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Popular Questions

  1. chele

    During my last urine sample at hospital they noted ketones in my urine. They never mentioned it, but it's got me worried. I'm seeing midwife on Friday and will do another test, but why on earth are there ketones in my urine??!!
    I ate a sandwich before my sample so it's not due to low carbs. I'm not dieting. Ok I've put no weight on, but haven't lost any either (which I admit to finding weird as I've not exactly been eating healthily)
    What could it be due to? Should I worry?

  2. vicky84

    there was leukocytes in mine on thurs and i dont know what that means either!!

  3. chele

    leukocytes is when ur body is fighting off an infection. You might not even know you have one and could be anything such as your body recoverng from a small cut even.
    Anyone else any help on the ketones?

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

High Anion Gap Metabolic Acidosis

When acidosis is present on blood tests, the first step in determining the cause is determining the anion gap. If the anion gap is high (>12 mEq/L), there are several potential causes. High anion gap metabolic acidosis is a form of metabolic acidosis characterized by a high anion gap (a medical value based on the concentrations of ions in a patient's serum). An anion gap is usually considered to be high if it is over 12 mEq/L. High anion gap metabolic acidosis is caused generally by acid produced by the body,. More rarely, high anion gap metabolic acidosis may be caused by ingesting methanol or overdosing on aspirin.[1][2] The Delta Ratio is a formula that can be used to assess elevated anion gap metabolic acidosis and to evaluate whether mixed acid base disorder (metabolic acidosis) is present. The list of agents that cause high anion gap metabolic acidosis is similar to but broader than the list of agents that cause a serum osmolal gap. Causes[edit] Causes include: The newest mnemonic was proposed in The Lancet reflecting current causes of anion gap metabolic acidosis:[3] G — glycols (ethylene glycol & propylene glycol) O — oxoproline, a metabolite of paracetamol L — L-lact Continue reading >>

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Popular Questions

  1. sarahinparis

    I went away for my anniversary weekend with my husband and had several excellent gourmet meals, including bread and several desserts. I hadn't touched bread for over 9 weeks, and had only had a bite or two of dessert in all that time.
    I knew I'd put myself right back on plan after the weekend, and I have, but i wanted to know how long should I expect the carb-related water retention to remain after a few days off? How long to get back into ketosis?

  2. JerseyGyrl

    There is no one size fits all answer to that question. Everyone's body is different...but...typically, 2-3 days.

  3. Shen

    When I fell out of ketosis with a chicken quesadilla (63g carbs or something like that) my ketone levels were back up within 2 days. (I added some extra exercise too).

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A discussion of the anion gap, including its calculation and its use in categorizing metabolic acidoses, including multiple examples of acid-base interpretation.

Anion Gap

The anion gap is the difference between primary measured cations (sodium Na+ and potassium K+) and the primary measured anions (chloride Cl- and bicarbonate HCO3-) in serum. This test is most commonly performed in patients who present with altered mental status, unknown exposures, acute renal failure, and acute illnesses. [1] See the Anion Gap calculator. The reference range of the anion gap is 3-11 mEq/L The normal value for the serum anion gap is 8-16 mEq/L. However, there are always unmeasurable anions, so an anion gap of less than 11 mEq/L using any of the equations listed in Description is considered normal. For the urine anion gap, the most prominently unmeasured anion is ammonia. Healthy subjects typically have a gap of 0 to slightly normal (< 10 mEq/L). A urine anion gap of more than 20 mEq/L is seen in metabolic acidosis when the kidneys are unable to excrete ammonia (such as in renal tubular acidosis). If the urine anion gap is zero or negative but the serum AG is positive, the source is most likely gastrointestinal (diarrhea or vomiting). [2] Continue reading >>

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Popular Questions

  1. Jorryan2

    Hi, I'm new here. I've been doing intermittent fasting for awhile. I eat once a day between 6pm and 7pm. I try to keep my calories around 1100/day. I usually don't pay attention to what makes up that 1100 calories but I've decided I'd like to try keto now as well. Is it possible to follow the 2 plans at the same time?

  2. KBDelight

    short answer, yes.
    You'll want to do some research on how to structure you're one meal to ensure you get enough fat and protein and limit carbs. 1100 calories seems very low, but if that is what works for you. I cant speak to how that might effect ketosis though.
    Try using https://keto-calculator.ankerl.com/
    49 to see your needs. I'd shoot for the 75/20/5 ratio.

    Good Luck and let us know how it works out for you.

  3. yayhowfun

    100% yes! Loads of folks on this forum do daily IF with extended fasts as well. Keto and IF pair wel together because eating keto keeps you satiated longer than eating carb heavy meals.

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