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Nervous Ketosis In Cattle

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Prof Stephen LeBlanc from Canada on Ketosis in dairy cows.

Plasma Metabolic Profiling Of Dairy Cows Affected With Clinical Ketosis Using Lc/ms Technology

Background: Ketosis in dairy cattle is an important metabolic disorder. Currently, the plasma metabolic profile of ketosis as determined using liquid chromatography–mass spectrometry (LC/MS) has not been reported. Objective: To investigate plasma metabolic profiles from cows with clinical ketosis in comparison to control cows. Animals and methods: Twenty Holstein dairy cows were divided into two groups based on clinical signs and plasma β-hydroxybutyric acid and glucose concentrations 7–21 days postpartum: clinical ketosis and control cows. Plasma metabolic profiles were analyzed using LC/MS. Data were processed using principal component analysis and orthogonal partial least-squares discriminant analysis. Results: Compared to control cows, the levels of valine, glycine, glycocholic, tetradecenoic acid, and palmitoleic acid increased significantly in clinical ketosis. On the other hand, the levels of arginine, aminobutyric acid, leucine/isoleucine, tryptophan, creatinine, lysine, norcotinine, and undecanoic acid decreased markedly. Conclusion: Our results showed that the metabolic changes in cows with clinical ketosis involve complex metabolic networks and signal transduction. Continue reading >>

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  1. JeffNY

    Well instead of dealing with milk fever, we had to deal with Nervous Ketosis with our Jersey. On Thursday she began to act weird, doing this weird chewing thing, was not aware of her surroundings, didn't kick much which is strange for her. So the first think you think is "Milk fever". Well called the vet, he came, and said that she has nervous ketosis, not milk fever. Did an IV of glucose, and she came back around fairly quickly, ate her grain there after. But what a strange thing, they go nuts. She would lick her shoulder, and the vet said he has seen ones that have licked through the hide, because they dont know what they are doing. He has heard of cases where they will chase you down, because they are simply out of their mind. Another vet told us that they have chased down and taken on skid steers. This one particular animal he treated, was biting the curb, and taking her teeth out. It went to her head and never cured, it went too far. Amazing how something that can be simple to remedy, can do what it does. Makes you wonder, what other animals have been killed off because it was though to be Mad Cow (such as Europe), yet it might have been nervous ketosis. They do want to go down, they do act strange, so who knows? She is better, and being treated for it. He said it typically happens in well conditioned animals, ones with a lot of back fat, and when they are new into milking they begin drawing from their back fat. This causes some sort of nutrient imbalence, which causes improper sugar use. It's weird, almost sounds sorta like a diabetes thing. What I noticed that seemed strange, was the fact she was down to 19-20lbs from 25-27lbs (per milking, being 50-52lbs day). So sure enough, Thursday AM she begins to act strange. Was told by another vet animals with nervous ketosis have chased skid steers down, and the vet that came told us they have chased humans down. Once again, it goes to show you, catch something early and you can usually nip it in the butt. Fun thing about dairy, it is a challenge. Boy has it been a challenge so far, beef animals are a piece of cake to raise.
    Jeff

  2. pygmywombat

    Wow. I have heard of ketosis, but not nervous ketosis. I wonder, aside from cows with it who are then killed for BSE, if its also mistaken for rabies?

  3. JeffNY

    Rabies symptoms and Nervous Ketosis symptoms are very very similar, and the vet said if they don't respond to treatment, then it could have been rabies. Which was just great, would of had to go get the series of shots .
    Jeff

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The Biting Cow, July 2012

I was called out to Farmer J on Tuesday evening who is running a dairy herd. On the phone the farmer told me he had a poorly cow. Arriving on farm there was a cow frantically licking the wall and the ground. She was absolutely fine that morning in the parlour and started her strange “licking” behaviour in the afternoon. For examination we run her into a race where she started wildly pressing forwards and biting the gate. Overall examination (as far as was possible given her behaviour), she had high fever, 104.5F, 40.3C, her rumen wasn’t working and her faeces were very soft. Except this and the neurological signs, no other clinical signs were observed. The cow wasn’t sensitive to touch but the gate biting became worse and she started to bite anything in her way, even trying to bite the air. Suspected prognosis was an infection that had gone through the blood/brain barrier, or some infection combined with nervous acetonemia. Nervous Acetonemia is an intoxication by circulating ketone bodies. This is caused by energy deficiency. Signs of simple but already clinical ketosis are cows off feed and lethargy, hence also called “slow fever”. In ketosis cases that have become wo Continue reading >>

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Popular Questions

  1. JeffNY

    Well instead of dealing with milk fever, we had to deal with Nervous Ketosis with our Jersey. On Thursday she began to act weird, doing this weird chewing thing, was not aware of her surroundings, didn't kick much which is strange for her. So the first think you think is "Milk fever". Well called the vet, he came, and said that she has nervous ketosis, not milk fever. Did an IV of glucose, and she came back around fairly quickly, ate her grain there after. But what a strange thing, they go nuts. She would lick her shoulder, and the vet said he has seen ones that have licked through the hide, because they dont know what they are doing. He has heard of cases where they will chase you down, because they are simply out of their mind. Another vet told us that they have chased down and taken on skid steers. This one particular animal he treated, was biting the curb, and taking her teeth out. It went to her head and never cured, it went too far. Amazing how something that can be simple to remedy, can do what it does. Makes you wonder, what other animals have been killed off because it was though to be Mad Cow (such as Europe), yet it might have been nervous ketosis. They do want to go down, they do act strange, so who knows? She is better, and being treated for it. He said it typically happens in well conditioned animals, ones with a lot of back fat, and when they are new into milking they begin drawing from their back fat. This causes some sort of nutrient imbalence, which causes improper sugar use. It's weird, almost sounds sorta like a diabetes thing. What I noticed that seemed strange, was the fact she was down to 19-20lbs from 25-27lbs (per milking, being 50-52lbs day). So sure enough, Thursday AM she begins to act strange. Was told by another vet animals with nervous ketosis have chased skid steers down, and the vet that came told us they have chased humans down. Once again, it goes to show you, catch something early and you can usually nip it in the butt. Fun thing about dairy, it is a challenge. Boy has it been a challenge so far, beef animals are a piece of cake to raise.
    Jeff

  2. pygmywombat

    Wow. I have heard of ketosis, but not nervous ketosis. I wonder, aside from cows with it who are then killed for BSE, if its also mistaken for rabies?

  3. JeffNY

    Rabies symptoms and Nervous Ketosis symptoms are very very similar, and the vet said if they don't respond to treatment, then it could have been rabies. Which was just great, would of had to go get the series of shots .
    Jeff

  4. -> Continue reading
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Nervous Ketosis In Buffalo-a Case Report.

www.IndianJournals.com Members Copy, Not for Commercial Sale Downloaded From IP - 14.139.59.242 on dated 4-Feb-2015 www.IndianJournals.com Members Copy, Not for Commercial Sale Downloaded From IP - 14.139.59.242 on dated 4-Feb-2015 www.IndianJournals.com Members Copy, Not for Commercial Sale Downloaded From IP - 14.139.59.242 on dated 4-Feb-2015 Continue reading >>

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Popular Questions

  1. JeffNY

    Well instead of dealing with milk fever, we had to deal with Nervous Ketosis with our Jersey. On Thursday she began to act weird, doing this weird chewing thing, was not aware of her surroundings, didn't kick much which is strange for her. So the first think you think is "Milk fever". Well called the vet, he came, and said that she has nervous ketosis, not milk fever. Did an IV of glucose, and she came back around fairly quickly, ate her grain there after. But what a strange thing, they go nuts. She would lick her shoulder, and the vet said he has seen ones that have licked through the hide, because they dont know what they are doing. He has heard of cases where they will chase you down, because they are simply out of their mind. Another vet told us that they have chased down and taken on skid steers. This one particular animal he treated, was biting the curb, and taking her teeth out. It went to her head and never cured, it went too far. Amazing how something that can be simple to remedy, can do what it does. Makes you wonder, what other animals have been killed off because it was though to be Mad Cow (such as Europe), yet it might have been nervous ketosis. They do want to go down, they do act strange, so who knows? She is better, and being treated for it. He said it typically happens in well conditioned animals, ones with a lot of back fat, and when they are new into milking they begin drawing from their back fat. This causes some sort of nutrient imbalence, which causes improper sugar use. It's weird, almost sounds sorta like a diabetes thing. What I noticed that seemed strange, was the fact she was down to 19-20lbs from 25-27lbs (per milking, being 50-52lbs day). So sure enough, Thursday AM she begins to act strange. Was told by another vet animals with nervous ketosis have chased skid steers down, and the vet that came told us they have chased humans down. Once again, it goes to show you, catch something early and you can usually nip it in the butt. Fun thing about dairy, it is a challenge. Boy has it been a challenge so far, beef animals are a piece of cake to raise.
    Jeff

  2. pygmywombat

    Wow. I have heard of ketosis, but not nervous ketosis. I wonder, aside from cows with it who are then killed for BSE, if its also mistaken for rabies?

  3. JeffNY

    Rabies symptoms and Nervous Ketosis symptoms are very very similar, and the vet said if they don't respond to treatment, then it could have been rabies. Which was just great, would of had to go get the series of shots .
    Jeff

  4. -> Continue reading
read more

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