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Metformin Myocardial Infarction

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Acc: Metformin No Help In Mi Recovery

For best viewing, click the bottom right corner for full screen. Click here for more ACC 2014 video coverage. by Crystal Phend Crystal Phend, Senior Staff Writer, MedPage Today This article is a collaboration between MedPage Today and: WASHINGTON -- Metformin started soon after reperfusion in the acute setting didn't help cardiac function recover in non-diabetic heart attack patients, a trial showed. Left ventricular ejection fraction was no different with a 4-month course of the drug started immediately after percutaneous intervention for acute ST-segment myocardial infarction (STEMI) than with placebo (53% versus 55% of predicted, P=0.096). N-terminal pro-brain natriuretic peptide (NT-proBNP) as a marker of cardiac stress came out at an identical 167 ng/L in both groups at that point, Chris Lexis, MD, of University Medical Center Groningen, the Netherlands, and colleagues found. "The current results do not support use of metformin in this setting ," Lexis concluded here at the American College of Cardiology meeting and simultaneously online in the Journal of the American Medical Association. That wasn't surprising, Howard Weintraub, MD , of NYU Langone Medical Center in New York Continue reading >>

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  1. mindhunter88

    Just received a blood glucose meter! What are the proper protocols for testing fasted blood sugar and what range is considered to be healthy? Additonally, what is the best method for using this meter to test my reaction to artificial sweeteners, which may be the culprits of my current 7 week stall?

  2. richard

    In general a fasting value of 3.9 - 5.5 mmol/l (70-100 mg/dl) is a normal result.
    Officially the ADA recommends for someone with diabetes: 4.5–7.2 mmol/L (80–130 mg/dl )
    2 hours after a meal a normal result is less than 7.8 mmol/L (140 mg/dl).
    For a diabetic managed with drugs by the ADA the expected values are less than 10.0 mmol/L (180 mg/dl).
    I vehemently disagree with the ADA on both the fasting and the pp numbers. We have a right to normal glucose and on a keto diet we can have just that.
    So glucose jumps around like a cat on a hot tin roof and is affected by a lot of things. But there are specific times to test that are less subject to external influence.
    You can test first thing in the morning. That will not be affected by food, and that value day to day will tell you how your overall glucose control is going. If you do that and then try an intervention and your numbers start going a little lower, then the intervention is improving your glucose control. However it's worth noting that that morning fasted test is still subject to influence - for example @tdseest found that whenever he had a nightmare that his glucose was significantly elevated ... so you really need to smooth other the day to day changes and look at the long term trend.
    Another common place to test is 2 hours AFTER eating. That post-prandial (after digesting) measurement should return to normal ranges 90-100 mg/dl in normal people within 2 hours of eating a meal, in a type 2 diabetic it could stay high for 4-5 hours.
    I wrote an article on my blog on how to chart a glucose curve to test foods
    easylocarb.com
    571
    Charting a glucose curve - Easy Lo-Carb
    How to use a diabetic glucose meter to test how your body will respond to specific foods by plotting a Glucose Curve in response to a food challenge.

  3. mindhunter88

    Exactly and succinctly what I was searching for. Thank you!

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What is the myocardial infarction !!

Effect Of Metformin On Metabolites And Relation With Myocardial Infarct Size And Left Ventricular Ejection Fraction After Myocardial Infarction

Effect of Metformin on Metabolites and Relation With Myocardial Infarct Size and Left Ventricular Ejection Fraction After Myocardial Infarction Effect of Metformin on Metabolites and Relation With Myocardial Infarct Size and Left Ventricular Ejection Fraction After Myocardial Infarction Eppinga, Ruben N; Kofink, Daniel; Dullaart, Robin P F; Dalmeijer, Geertje W; Lipsic, Erik; van Veldhuisen, Dirk J; van der Horst, Iwan C C; Asselbergs, Folkert W; van der Harst, Pim (2017) Circulation-Cardiovascular genetics, volume 10, issue 1 BACKGROUND: Left ventricular ejection fraction (LVEF) and infarct size (ISZ) are key predictors of long-term survival after myocardial infarction (MI). However, little is known about the biochemical pathways driving LV dysfunction after MI. To identify novel biomarkers predicting post-MI LVEF and ISZ, we performed metabolic profiling in the GIPS-III randomized ... read more clinical trial (Glycometabolic Intervention as Adjunct to Primary Percutaneous Intervention in ST Elevation Myocardial Infarction). We also investigated the metabolic footprint of metformin, a drug associated with improved post-MI LV function in experimental studies. METHODS AND RESULTS: Continue reading >>

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  1. Pokeyo0

    Dave recommends a tablespoon of raw honey before bed to improve sleep quality..
    Does this break ketosis and should I do it everyday?
    is it level tablespoon or a tablespoon covered with honey like I consume which is like 2 tablespoons of leveled honey.

  2. jakejoh10

    I've heard Dave say that it doesn't break ketosis, but I don't remember the specific mechanisms behind it.

  3. Rod

    1-2 TSP not TBSP. It will not kick you out ketosis at those doses.
    Everything I learned about "biohacking" has been baby steps to "circadian biology", that's where the real biohacking comes in. You can buy a bunch of cool shit to "hack" but if you don't have context, you're not winning. Paleo is just a brand now and too many have opinions, it's on you to read and reread the material to not only find truth but to connect the dots. Much love to everyone who has helped me on my journey for restoring my health, please keep in touch. Feel free to message me with health questions [email protected]

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For med supp quotes, call us at 1-888-832-3132 or click here: http://saferetirements.com/medsuppquote. Please like this video and subscribe to our channel! This video will cover the basics of Medicare: Part A and Part B (called Original Medicare, and Part C and Part D. Medicare Part A is Hospitalization. Think of the "A" as "admission" to a hospital. It has a $1,288 deductible per 60-day benefit period, so for the first 60 days, this will be your only cost. If you have a long hospital stay over 60 days, you will incur a co-pay of over $300 per day, and after 90 days, even more. It's important to note that if you go are admitted then released, and more than 60 days go by, and you are admitted again within the same calendar year, you will incur this $1,288 deductible again. This is one reason why some people buy a Medicare supplement: it will pay this deductible and these co-pays for an additional 365 days. Part A also covers hospice, skilled nursing (up to 20 days in full but a supplement covers up to 100), and home health care. Medicare Part B is Medical coverage. This covers 80% of Medicare-approved charges for doctor visits, lab tests, bloodwork, x-rays, CT scans, MRIs, PET scans

Drugs For Diabetes: Part 1 Metformin

This website is intended for UK healthcare professionals only Log in | Register September 2010Br J Cardiol 2010;17:2314 Leave a comment Authors: James G Boyle, Gerard A McKay, Miles Fisher Royal Alexandra Hospital, Paisley, PA2 9PN. University Medical Unit, Glasgow Royal Infirmary, Glasgow, G4 0SF. Metformin is one of the oldest oral treatments to reduce hyperglycaemia in people with diabetes. Gastrointestinal side effects are common, and metformin should be used with caution in patients with renal impairment because of the slight risk of lactic acidosis. In the United Kingdom Prospective Diabetes Study (UKPDS) patients treated with metformin had a significant reduction in myocardial infarction and mortality that was not demonstrated in patients treated with sulphonylureas or insulin. The fact that metformin significantly reduces cardiovascular events plus reduces weight has meant that metformin is the drug of first choice in guidelines for the treatment of type 2 diabetes. There are no longer concerns about using metformin in patients with chronic heart failure, other than in patients with associated renal failure, or during episodes of acute left ventricular failure when metform Continue reading >>

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  1. carojane

    Hi! I started a low carb diet 20 days ago, and I was smack in the middle of my period (weird time to start a diet, I know...). Today, my period came back. Usually I have a pretty long cycle - 35, I think... and I've NEVER had two in one month.
    Has anyone else experienced this? What could be the cause - all those hormones they inject into meat? the lowered insulin or increased iron? estrogen released by burning fat? Okay... I've been googling this, too.
    Are there any other surprises I should look forward to?

  2. dcapulet

    Hi there,
    I don't have an answer for you, but I'm actually going through the same thing - I have and IUD, and have not had a period in about 3.5 years. But two days ago (after about 3 weeks low carb) I got my period.
    Maybe there is something to it...

  3. PhoenixRisingAgain

    Quote:

    Originally Posted by dcapulet
    Hi there,
    I don't have an answer for you, but I'm actually going through the same thing - I have and IUD, and have not had a period in about 3.5 years. But two days ago (after about 3 weeks low carb) I got my period.
    Maybe there is something to it... How incredibly odd! I have not had period in many years, I take the Depo Provera shot. One way I can ALWAYS tell that I am actually losing weight: I start to have spotting! The first few times it happened, I thought it was just an odd coincidence. But it happens EVERY SINGLE TIME I get going on the weight loss.
    I've been doing low carb since right before Christmas, and have lost about 17.5 lbs; and sure enough, I am spotting like mad.
    Off to do some Googling of my own now...I am very intrigued by this.
    Phoenix

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