Metformin Contraindications Heart Failure\

Share on facebook

Metformin May Reduce All-cause Mortality In Patients With Congestive Heart Failure

A systematic review of 17 observational studies found that metformin was associated with a reduction in all-cause mortality in patients with type 2 diabetes and chronic kidney disease, congestive heart failure or chronic liver disease with hepatic impairment. Metformin was also associated with fewer heart failure readmissions in patients with chronic kidney disease or congestive heart failure. Lead researcher Matthew J. Crowley, MD, MHS, of Duke University and the Durham Veterans Affairs Medical Center in North Carolina, and colleagues published their results online Jan. 2 in the Annals of Internal Medicine. The U.S. Department of Veterans Affairs funded the study. When the FDA approved metformin in 1994, the drug became the initial treatment option for many people with type 2 diabetes in the U.S., according to the researchers. However, the FDA required a label warning against using metformin in patients with chronic kidney disease and recommended caution for patients with congestive heart failure and chronic liver disease. The researchers noted that the FDA in 2006 removed congestive heart failure as a contraindication to metformin use, although the agency still cautions against t Continue reading >>

Share on facebook

Popular Questions

  1. Jeanwf

    Hi. Anyone out there suffer from feeling really, really hot doing Keto Diet. My face is as red as beetroot in the mornings and throughout the day I get several hot flushes. Any ideas?:explode:

  2. rachelrb85

    Could it be menopause?

  3. Jeanwf

    I have finished now with the menopause as I started when I was 46! Grrrrr. Could it be because I am burning fat?

  4. -> Continue reading
read more close

Related Articles

Popular Articles

More in ketosis