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Metformin Antidote

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Oral Hypoglycemic Agent Toxicitytreatment & Management

Oral Hypoglycemic Agent ToxicityTreatment & Management Author: David Tran, MD; Chief Editor: Timothy E Corden, MD more... The main goal in oral hypoglycemic agent exposure is supportive care, which includes airway, breathing, and circulation. Intravenous administration of glucose rapidly resolves the effects of hypoglycemia. Its onset is quicker than oral administration of sugar, and it is safer in patients with a depressed mental status who should not take anything by mouth for fear of aspiration. Glucagon is helpful and can be administered intravenously, intramuscularly, or subcutaneously. Glucagon is particularly useful in the intramuscular mode when intravenous access cannot be obtained immediately. Generally, all symptomatic patients who present with hypoglycemia need admission to the hospital in a monitored setting. Patients who remain asymptomatic and who do not develop hypoglycemia in the first 8-12 hours may be discharged safely home. However, the data from one study suggest that because accidental ingestion of sulfonylurea results in delayed and often prolonged hypoglycemia, admission for at least 16 hours is recommended, with frequent glucose monitoring. [ 17 ] At minim Continue reading >>

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  1. FJoker09

    Keto doesn't work for everyone.

    Keto only worked for the first couple of weeks and did not lose anymore fat for the next 6 weeks even after reducing my calorie and fat count. I am going back to a low fat, low carb diet.
    Has anybody else experienced this? Photo attached.
    Height: 5'8"
    Weight: 170
    bf% about 14%
    Waist: 33"
    Age: 38
    20 min. HIIT 5XWeek
    Weights: 5XWeek.

    Attached Images
    IMG_0014.JPG‎ (41.6 KB, 462 views)

  2. kdhoward83

    Originally Posted by FJoker09
    20 min. HIIT 5XWeek
    Weights: 5XWeek.

    Theres such a thing as too much exercise. What kind of calorie intake were you doing?

  3. FJoker09

    Originally Posted by kdhoward83
    Theres such a thing as too much exercise. What kind of calorie intake were you doing?

    2,000 calories in 5 meals and a PWO drink (25g Protein) not included in the calorie count.

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A Comparison Between The Effects Of Metformin And N -acetyl Cysteine (nac) On Some Metabolic And Endocrine Characteristics Of Women With Polycystic Ovary Syndrome

Full Terms & Conditions of access and use can be found at Download by: [Kashanian Maryam] Date: 25 December 2015, At: 00:26 ISSN: 0951-3590 (Print) 1473-0766 (Online) Journal homepage: A comparison between the effects of metformin and N-acetyl cysteine (NAC) on some metabolic and endocrine characteristics of women with Forough Javanmanesh, Maryam Kashanian, Maryam Rahimi & Narges To cite this article: Forough Javanmanesh, Maryam Kashanian, Maryam Rahimi & Narges Sheikhansari (2015): A comparison between the effects of metformin and N-acetyl cysteine (NAC) on some metabolic and endocrine characteristics of women with polycystic ovary syndrome, Gynecological Endocrinology, DOI: 10.3109/09513590.2015.1115974 To link to this article: Department of Obstetrics & Gynecology, Firoozgar Teaching Hospital, Iran University of Medical Sciences, Tehran, Iran, & Gynecology, Akbarabadi Teaching Hospital, Iran University of Medical Sciences, Tehran, Iran, and Medicine, University of Southampton, Southampton, UK Objective: To compare N-acetyl cysteine (NAC) and metformin on polycystic ovary syndrome Method: Study was performed as a randomized double-blind clinical trial on women with diagnosis of Continue reading >>

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  1. Kiley

    I'm a 45 year old woman and was recently diagnosed as being a borderline diabetic. My doctor prescribed some medication, but before filling it I decided to do some research on the internet which led me to the methods. After reading this ebook and applying the methods, my scepticism turned to 100% belief. I noticed that my energy levels increased significantly and I felt more rested in the morning, my symptoms started going away.
    I am very happy to tell you that I have been feeling better than I have felt in years and my doctor informed me that he will be taking me off my prescriptions if I keep this up.
    I recommend you use the Type 2 Diabetes Destroyer to naturally reverse your diabetes.

  2. Taddeo

    Why does Diabetic Ketoacidosis cause stroke?

    This Site Might Help You.
    RE:
    Why does Diabetic Ketoacidosis cause stroke?
    why is stroke a complication of DKA?

  3. Coral

    Shocking New Diabetes Research Revealed : http://Help.DiabetesGoGo.com

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Metformin-related Acidosis In A Woman While Performing Haj: A Conservative Approach Ansari Rs, Mady Af, Qutub Ho, Althomaly E, Alzayer Za, Moulana Aa - Saudi J Kidney Dis Transpl

Metformin is a biguanide that enhances the release of glucose from the liver and the insulin effect on peripheral tissues thus decreasing the blood glucose. The most serious sideeffect of metformin is lactic acidosis due to inhibition of hepatic gluconeogenesis and/or reduction of conversion of lactic acid, pyruvic acid or alanine to glucose. The yearly incidence of lactic acidosis in previous reports was less than five episodes in every 100,000 treated individuals. Still, there is no particular antidote for metformin-induced lactic acidosis and its treatment mainly involves the correction of acidemia. [1] Considerable efficacy has been observed in the use of hemodialysis to treat the metformin-induced lactic acidosis. Hemodialysis application is currently recommended in patients with severe metabolic acidosis (pH < 7.1) and renal failure. It has been shown that plasma metformin concentrations are only slightly increased when the estimated glomerular filtration rate is 30 mL/ min/1.73 m2. [2] We present a case of successful management of metformin-associated metabolic acidosis, treated simply with intravenous sodium bicarbonate and aggressive hydration and intensive monitoring. Ou Continue reading >>

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Popular Questions

  1. RunAndPunch

    How much sleep do you get on keto?

    Before starting keto, I slept around 8-9 hours a night. I've been doing a keto diet for about 2 months now, with the following results:
    --way more energy throughout the day
    --having to eat less
    --improved physical stamina
    --better mental clarity
    --only need about 5-6 hours of sleep per night
    The last one is what I'm researching right now.
    So for those on keto right now, how's your sleep schedule compared to non-keto?

  2. alexwynveen

    I tend to get 5-6 hours, except on the weekends where I drug myself with sleep aids to force myself to get ~8. I don't really choose to sleep so little, but as soon as I hit those times my body is all like "GET THE HELL UP" and I cant get back to bed (usually happens at 4:30am, so I eat and lift at 6). I would say that my sleeping hasn't really had much of a change on my sleep, but I definitely wouldn't need to sleep as much as before, due to the stability of energy I have. I never really go to bed "beat".

  3. sambshep

    Keto hasn't affected my sleep, it's the same as it is on a non-keto diet.

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