Metabolic Acidosis In Liver Failure

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Your liver is the largest internal organ in your body, its about the same size as a football, and is located on the right hand side under the ribcage Purpose: 99% of nutrients we consume pass through the liver... Security, Breakdown Assistance, and Fuel The liver is part of your bodys critical security system, its one of the main components in the breakdown of the raw materials coming in through your gob, and its part of the power producing system that keeps you moving like an all-star athletewell, at least it keeps you moving! The Secret Service Think about the liver as part of your body's personal secret service, continuously on the lookout for evil threats that it can destroy with one swift movement (whilst speaking inconspicuously into a really visible earpiece!) Your secret service removes all the toxins - that's including toxins from drugs and alcohol...It deals with some of the chemicals by disarming them and beating them up until theyve been turned into less harmful toxins... or it will immobilize them by covering them in a chemical film before shipping them out of the body and straight down the toilet. The Breakdown All the food that goes into your body must be broken down

The Short Term Prognosis In Alcoholic Liver Disease With Metabolic Acidosis

The Short Term Prognosis in Alcoholic Liver Disease with Metabolic Acidosis The Korean Journal of Hepatology 2004;10(2): 117-124. The Short Term Prognosis in Alcoholic Liver Disease with Metabolic Acidosis Ki Sun Bae , Kwon Yoo , You Kyung Cho , Ki Nam Shim , Sung Ae Jung , Il Hwan Moon Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea Alcoholic liver disease with metabolic acidosis may have possible causes such as alcoholic ketoacidosis, diabetic ketoacidosis, lactic acidosis. Salicylate, methanol, and ethylene glycol intoxication should also be considered. The aim of this study was to investigate the short-term prognostic factors in patients with alcoholic liver disease with metabolic acidosis. Clinical data related to twenty-nine patients with alcoholic liver disease and metabolic acidosis was analysed retrospectively. Patients were divided into two groups according to the outcome (survival or death). Past medical history, and physical, laboratory and radiologic data at admission were compared. The amount of daily alcohol intake differed significantly between the two groups (P=0.034), but duration and total amount of alcohol intake did no Continue reading >>

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  1. SVL

    So I understand this to be deep rapid respirations, as part of the signs of DKA. It's a result of the acidosis, and a need for air... so the body rapidly tries to expel CO2.
    So... how on earth do you treat the respirations? I do understand you would need to treat the acidosis, but the question on my study guide says to know how to treat Kussmaul's Respirations.
    A class mate told me with a brown paper bag? That doesn't seem complicated enough to me, and I can't find anything in my book about it.

  2. Guest

    You have to treat the acidosis first and if that doesn't correct it--Intubation. I don't know Sarah usually when they get to that point they are on their way out.

  3. BlueRidge

    Your classmate is confusing Kussmaul's with hyperventalation, which is caused by breathing too deeply and/or quickly. Hyperventalating leads to the UNINTEDED loss of of too MUCH CO2, leading to dizziness and tingling of extremities. That treatment IS the brown paper bag or breathing into cupped hands to rebreath in more CO2. This occurs with overexcitment or during labor with controlled breathing patterns (like Lamaze).
    As you said, Kussmaul's is an attempt to reverse metabolic acidosis by blowing off Bicarb as a compensatory effort. These are spontaneous and under autonamic control, so you can NOT "treat the respirations" any more than you can help a patient "control" full blown labor contractions or autonamic dysreflexia in a pt with spinal cord injury.
    So, as TNN said, the treatment is to control the underlying metabolic issue with meds, fluids, mechanical oxygenation if needed. Th pH has to brought up to a level compatable with human life.

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The Electron Transport Chain & complexes I-IV that pump protons out of the Mitochondria by the transfer of the electrons carried on NADH & FADH2 to maintain the concentration gradient of the protons "high in the intermembrane space & low in the matrix of the Mitochondria" this video is made by HarvardX on edX https://goo.gl/KDZmML http://bit.ly/2hqwmRB

Hypoketotic Hypoglycemia, Metabolic Acidosis, Toxic Liver Disease: Causes & Diagnoses | Symptoma.com

Causes of metabolic acidosis There are many causes. [patient.info] Diseases and drugs that impair mitochondrial function can cause lactic acidosis. [merckmanuals.com] metabolic , Metabolic acidosis NOS , Metabolic Acidoses , Acidosis, Metabolic , Acidoses, Metabolic , Metabolic Acidosis , acidosis metabolic , metabolic acidosis disorder [fpnotebook.com] Also, severe electrolye abnormalities (hyponatremia, hypophosphatemia, hypokalemia, hypomagnesemia, also metabolic acidosis). [errolozdalga.com] Progress in liver diseases . 3 : 28298. [en.wikipedia.org] Instead of being harmlessly metabolized and bound to glucuronates and sulfates, excessive acetaminophen compounds enter CYP protein-mediated metabolic reactions in the liver [lecturio.com] Long Chain Hydroxyacyl-CoA Dehydrogenase Deficiency Treatment : It is important to avoid fasting to prevent hypoketotic hypoglycemia. [emilytam.com] Clinical considerations: Poor feeding, vomiting, lethargy Hypoglycemia Metabolic acidosis Hepatomegaly Cardiac insufficiency History of sudden unexpected death in a sibling [archildrens.org] Symptoms associated with LCHAD deficiency are due to low levels of energy and the toxic build-up of fatty acid Continue reading >>

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  1. doug684

    Ketosis can cause damage to kidneys and liver

    So I'm about to fire up a keto regiment (again, I always fall off the wagon after about 2 months). Just searching around as it seems the other two times I started it I tend to have diarrhea a lot. Anyway, came across this. Any truth to this?

    When protein is deflected in this manner, it releases nitrogen into the blood stream, placing a burden on the kidneys as they try to excrete excessive urinary water due to sodium loss. When fat is likewise deflected, the breakup releases fatty acids, or ketones, into the bloodstream, further burdening the kidneys. If ketosis continues for long periods of time, serious damage to the liver and kidneys can occur, which is why most low-carbohydrate, or ketogenic diets recommend only short-term use, typically 14 days.

  2. Eileen

    I don't know where to start.
    Okay, I'll start with the assumption that keto is high protein. No, it's not, it's moderate protein compared with standard BB diets. The dangers of protein to the kidneys would apply far more to a 40/40/20 diet than to a keto one. If they applied. But they don't. People with damaged kidneys can not tolerate high levels of protein. So some "experts" have extrapolated this to mean that high levels of protein can damage healthy kidneys. Except there has not been one single case of this ever, in the history of recorded medicine.
    Most keto diets do not recommend 14 days or less, that's the classic way to do it wrong. Most low carb diets recommend making it a lifestyle.
    And again, where is the evidence that ketones do any damage to liver or kidneys or any other organ? Not a single case. The closest to damage from a low carb diet comes from the odd nutcase who tries to combine keto with no liquid, which does put stress on the kidney (just like any other diet which does not include liquid) but because keto is slightly diuretic, you'll see the effects a little quicker.

  3. doug684

    Originally Posted by Eileen
    The closest to damage from a low carb diet comes from the odd nutcase who tries to combine keto with no liquid, which does put stress on the kidney (just like any other diet which does not include liquid) but because keto is slightly diuretic, you'll see the effects a little quicker.

    There are people who try that? I don't see how. Keto makes me thirsty and will often drink constantly as long as my glass of water is full.

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Learn the anatomy of the human Small Intestine with this fun educational music video for children and parents. Brought to you by Kids Learning Tube. Don't forget to sing along. https://kidslearningtubeshop.com/prod... Watch Kids Learning Tube ad-free for $12 a YEAR! See the latest videos before anyone else in the world. Sign up today for ad-free video streaming for all Kids Learning Tube videos! https://www.patreon.com/kidslearningtube Support Kids Learning Tube by becoming a Patreon today at the link below! You can vote for the video of the week, get your name in the credits and support something you believe in! KLT Website: https://kidslearningtubeshop.com/ T-Shirts: https://kidslearningtubeshop.com/coll... Music Downloads: https://kidslearningtubeshop.com/coll... Facebook: https://www.facebook.com/kidslearning... Subscribe: http://www.youtube.com/c/kidslearning... Tweet Us: https://twitter.com/learningtube Instagram: https://instagram.com/kidslearningtube Add us on Google+: https://plus.google.com/+KidsLearning... iTunes: http://itunes.apple.com/album/id11928... Music: Copyright 2015, 2016, 2017, 2018 Kids Learning Tube Video: Copyright 2015, 2016, 2017, 2018 Kids Learning Tube

Fulminant Hepatic Failure In Small Animals

Fulminant Hepatic Failure in Small Animals Fulminant Hepatic Failure in Small Animals By Sharon A. Center, BS, DVM, DACVIM, Professor, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University Hepatobiliary Fluke Infection in Small Animals Fulminant hepatic failure is a syndrome defined by the abrupt loss of liver function, associated with hepatic encephalopathy (HE) and coagulopathy. Early, appropriate therapy is critical. In chronic or end-stage liver disease with an acute or chronic insult and in acute liver injury with no apparent underlying cause, treatment provides supportive care to allow time for hepatic regeneration and compensation. Specific treatment should be administered if an underlying cause is determined. Decontamination of oral, dermal, and enteric surfaces is mandatory if toxin exposure has occurred within 36 hr. If an adverse drug reaction is implicated, the drug in question must be discontinued and antidotes investigated. Life-threatening infection, cerebral edema, and coagulopathies are major complications. Attention to fluid, electrolyte, and acid-base balance, glycemic status, and nutritional support optimizes chance of survival. Re Continue reading >>

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  1. MyJourney

    > Ketosis and Sugar Alcohols

    I am trying to figure out why sugar alcohols or too many of them knock me out of ketosis?
    I know for a fact that I do not get a blood sugar spike since I have tested it a bunch of times but could my body still be producing a lot of insulin from these products even though my blood sugar doesnt go up?
    I know I am obviously confused and missing something somewhere but I hope someone can please enlighten me.
    From my understanding if my body thought the sugar alcohols were sugar I would get a blood sugar response as well as an insulin response.
    Can one happen without the other? Why is the result so dramatic with sugar alcohols?

  2. Squid

    I'm curious about this as well as I've noticed the same thing with myself. The sugar alcohols and splenda most definitely push me out of ketosis even though the net carbs are below 20.
    I assumed it was because these are carbs but not counted by atkins in the net carb account. It seems they do affect ketosis although maybe not enough to spike blood sugar. Just a thought. Curious what others have to say.

  3. toning_up

    I also get knocked out of ketosis by them. I assume that seeing they are treated by the body as alcohols, then ketosis ceases until they are burned just like it would with regular drinking alcohol. That's the only thing I can think of anyway.

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