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Metabolic Acidosis Hyperventilation

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Acid-base Balance

Patient professional reference Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find the Arterial Blood Gases article more useful, or one of our other health articles. Disorders of acid-base balance can lead to severe complications in many disease states.[1]Arterial blood pH is normally closely regulated to between 7.35 and 7.45. Maintaining the pH within these limits is achieved by bicarbonate, other buffers, the lungs and the kidneys. Primary changes in bicarbonate are metabolic and primary changes in carbon dioxide are respiratory. In the absence of any significant respiratory disease or hyperventilation, the primary cause is much more likely to be metabolic. However, central hypoventilation (eg, caused by CNS disturbance such as stroke, head injury or brain tumour) causes respiratory acidosis. In general, the kidneys compensate for respiratory causes and the lungs compensate for metabolic causes. Therefore, hyperventilation may be a cause of respiratory alkalosis or a compensatory mechanism for metabolic acidosis. Deep sighing respiration (Kussmaul Continue reading >>

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Popular Questions

  1. MariaMia816

    Can anyone tell me what an average weight loss per week or month is for 20 carbs a day? Im loosing soooooo slow.

  2. GSD_Mama

    I guess it will be different for everyone. My first two weeks I've lost about 10, of which water was probably 5-7lb. I'm going on my third month now and losing slow, sometimes I gain sometimes I lose, no rhyme or reason.

  3. stevieedge2015

    10lbs in a month. I'm trying to keep my calories to under 1500. I smoke like a chimney though so...aiming to get to 130 so I can quit and not worry about gaining 10lbs

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Metabolic Acidosis And Hyperventilation Induced By Acetazolamide In Patients With Central Nervous System Pathology

ACETAZOLAMIDE, a carbonic anhydrase inhibitor, is used in patients with meningeal inflammation, mild intracranial hypertension, and basal skull fractures to decrease the formation of cerebrospinal fluid (CSF). It causes mild metabolic acidosis by inhibiting the reabsorption of bicarbonate (HCO−3) ions from renal tubules. This effect has been used successfully in the treatment of patients with chronic respiratory acidosis with superimposed metabolic alkalosis 1 and central sleep apnea syndrome. 2 Life-threatening metabolic acidosis during acetazolamide therapy has been observed only in patients with renal impairment or 3 diabetes 4 and in elderly patients. 5 Severe metabolic acidosis, associated with acetazolamide, in the absence of other predisposing factors has not been reported in patients with central nervous system disease. We report three cases of severe metabolic acidosis and hyperventilation during acetazolamide therapy in normal doses in adult patients without renal impairment. A 35-yr-old man with a head injury underwent craniotomy for evacuation of a traumatic left temporal extradural hematoma. Postoperatively, the patient underwent mechanical ventilation to maintain a Continue reading >>

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Popular Questions

  1. samuelbreezey

    Hey guys,
    Who measures if they are in ketosis? If so, what do you use?
    I was looking at measuring to see if I am in Ketosis since I am just transitioning into the Keto way of life. Also I am looking at following a more TKD approach so would like to experiment and see how long I return to Keto when taking X amount of carbs as a pre workout.
    I was looking at glucose monitors but these seem expensive when compared to a Ketonix in the long run - https://www.ketonix.com/
    Thanks

  2. carbaholic

    Blood ketone monitoring is the only way to correctly check. The urine keto stix are a waste of time and money.

  3. metaStatic

    to elaborate; ketostix measure EXCESS ketones so are only relevant in the very early stages of nutritional ketosis or if you are diabetic.

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Technique of endotracheal intubation in neonate

Hypercapnea And Acidemia Despite Hyperventilation Following Endotracheal Intubation In A Case Of Unknown Severe Salicylate Poisoning

Hypercapnea and Acidemia despite Hyperventilation following Endotracheal Intubation in a Case of Unknown Severe Salicylate Poisoning 1Department of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada 2Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada Correspondence should be addressed to Shannon M. Fernando ; [email protected] Received 8 January 2017; Accepted 23 March 2017; Published 29 March 2017 Copyright 2017 Shannon M. Fernando et al. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Salicylates are common substances for deliberate self-harm. Acute salicylate toxicity is classically associated with an initial respiratory alkalosis, followed by an anion gap metabolic acidosis. The respiratory alkalosis is achieved through hyperventilation, driven by direct stimulation on the respiratory centers in the medulla and considered as a compensatory mechanism to avoid acidemia. However, in later stages of severe salicylate toxicity, patients become increasingly obtunded, w Continue reading >>

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Popular Questions

  1. olivo

    i went for my 35 wk check - am on weekly checks due to GD and polyhaydramnios - on thurs. there were ketones in my urine - what does that mean exactly?

  2. becksydee

    i had ketones in my urine when i went for my checkup (34wks) on monday - they wouldn't let me leave until it had been investigated so sounds like you got off lightly!
    it basically means that your body has stopped burning glucose as fuel and is burning fat & protein instead (ketosis) - in extreme cases it can mean you're suffering from ketoacidosis which is quite serious (& is the condition that the midwife/consultant would be worried about if they found ketones). it's diagnosed by testing blood gases & treated with IV fluids (due to dehydration) and insulin. if you had it, you would probably be feeling really rather ill (nausea, vomiting, stomach pain etc) and would also probably have smelly breath.

  3. notevenamousie

    EITHER that you've not been eating enough or you've not been drinking enough. Possibly both.

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