The Effect Of Lactic Acidosis On The Generation And Compensation Of Mixedrespiratory-metabolic Acidosis In Neonatal Calves.
1. Vet Rec. 2013 May 18;172(20):528. doi: 10.1136/vr.101192. Epub 2013 Mar 13. The effect of lactic acidosis on the generation and compensation of mixedrespiratory-metabolic acidosis in neonatal calves. (1)First Clinic for Reproductive Medicine, Department of Food Animals, Vetsuisse-Faculty, Clinic of Reproductive Medicine, University of Zurich, Winterthurerstr.260, CH 8057, Zurich, Switzerland. [email protected] Postnatal mixed respiratory-metabolic acidosis is common in calves, and dependingon its severity can impair vitality or even cause death. Carbon dioxide accounts for the respiratory component and L-lactate for the metabolic component of themixed acidosis, but it remains unclear which component determines the severityand duration of the acidosis. In a first attempt to clarify, this wasinvestigated retrospectively in 31 calves during the first two hours of life, andin 13 calves during the first three days of life. Venous blood was collected for blood gas analysis and measurement of acid-base variables and L-lactateconcentration. pH Was more strongly correlated with L-lactate concentration(r(2)=0.808) than with partial pressure of CO2 (pCO2, r(2)=0.418). Duration ofpa Continue reading >>