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Metabolic Acidosis Alcohol Intoxication

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

How To Correct High Anion Gap Metabolic Acidosis In Acute Alcohol...| Dailyrounds

palliative rx when ph < 7.2 bicarbonate supplementation dose= 0.3 (24 - pt's bicarb) wt (kg) 1/3 dose given as bollus remaining as infusion over 8 to 24 hr specific rx treat underline cause Dr Kieran V J Mullins Internal Medicine 11 Sep Metabolic acidosis with ethanol poisoning may be secondary to ketoanions or lactic acidosis. These are organic anion acidoses and as such treatment should centre on correction of associated abnormalities rather than administration of bicarbonate which has potential serious risks in such circumstances (intracellular acidosis, overshoot alkalosis, impaired O2 unloading due to left shift of the O2 dissociation curve, hypernatraemia, hypercapnia). Recall that in the presence of an optimised intravascular volume and normal hepatic function organic anions serve as avid bicarbonate precursors. It would have been helpful to have the PCO2 to assess the patient's degree of compensation (if any) and hence their reserve in terms of further respiratory compensation should the metabolic component evolve further. In the above patient I would optimise Intravascular filling with an isotonic crystalloid such as NaCl 0.9% and administer IV thiamine (remember that for Continue reading >>

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Popular Questions

  1. danielcruit

    What if I did 100g/day, or 50g/day?
    I'm trying to do this with my partner, and just due to life situation, we don't really have the ability to track religiously what we eat, and staying under 20g is not really possible, for reasons I don't want to get into now. What I'm interested in is simply whether weight loss will still occur at 100g or 50g/day, just more slowly than under 20g, or if we won't lose any weight at all.
    I'm also confused about calories- I'm really a beginner to this, but I was lead to believe that calories didn't matter, only how much carbs you ate, but I see people on this sub all the time asking "how many calories are you eating a day?" to people who say that they are having trouble losing weight on keto.
    Thanks so much for any insight, my understanding of this is really limited.

  2. anbeav

    Ketosis != weight loss
    Ketosis works for many because it makes eating at a deficit feel easier but it's not required for weight loss.
    Also most at less than 100 grams/day are transiently in ketosis.
    If you eat fewer calories than you need at 100 or 50 gram carb intake, you will lose weight. People lose weight eating at much higher carb intake. Keto is not the only way to lose weight (caveat: insulin resistance complicates this situation)
    Calories aren't all that matters, but they matter. For some they can achieve a caloric deficit eating to satiety, many others cannot and need to count calories. If you're not eating in a deficit, you will not lose weight. Calories mater.

  3. IRiseFromTheAshes

    I've never understood why carbs are limited to 0-50g/day, with emphasis of eating under 30g, if being under 100g will still keep you at some level of ketosis. I find it frustrating at times having to limit my vegetable intake of all things simply because I require a lot of calories / day (sometimes close to 4000), which means that proportionally I would have say, 40g of carbs from vegetable instead of 20g from someone eating 2000 calories.

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More info: https://goo.gl/iVdl1V?34348

Alcohol Intoxication

Alcohol intoxication is a significant risk factor for TBI, and TBI should be appreciated as a heterogeneous, dynamic pathophysiological process that occurs at the moment of impact and continues over time with sequelae potentially seen many years after the initial event (Currie et al., 2016). Young-chul Jung*, Kee Namkoong, in Handbook of Clinical Neurology , 2014 Alcohol intoxication refers to a clinically harmful condition induced by recent ingestion of alcohol, when alcohol and its metabolites accumulate in the blood stream faster than they can be metabolized by the liver. Due to the long history and widespread use of alcohol as a recreational beverage, the clinical manifestations of alcohol intoxication are usually not taken seriously and considered to subside spontaneously with time; however, the adverse effects of alcohol at sufficiently high levels can cause coma and respiratory depression. In addition, individuals who seek medical treatment for acute alcohol intoxication likely have additional medical problems related to chronic alcohol consumption or alcohol dependence. The aims of this chapter are to delineate and discuss: (1) the acute and chronic effects of ethanol on o Continue reading >>

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  1. Lolworth

    131


    Truvia (Stevia) is 99% Carbs - so why all the love for it on here? (i.imgur.com)
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  2. toot__toot

    Steviol glycoside chemically is a carbohydrate, but it isn't broken down to glucose and it has no effect on insulin levels.

  3. Lolworth

    Thank you, this seems to be the answer. Interesting - magic carbs!

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Alcohol Toxicity - Cancer Therapy Advisor

Alcohol toxicity or poisoning is caused by drinking large quantities of alcohol in a short period of time. According to Centers for Disease Control (CDC) data released January 2015, an average of 6 people died of alcohol poisoning each day in the US from 2010-2012. Seventy-six percent of alcohol poisoning deaths are among adults ages 35-64 years old, the majority of whom are men and non-Hispanic whites. While alcohol dependence was identified as a factor in 30% of alcohol poisoning deaths, binge drinking (defined as more than 5 drinks on an occasion for men or 4 or more drinks on an occasion for women) can also lead to death from alcohol poisoning. A standard drink in the US is considered either 12 ounces (oz) of beer (5% alcohol), 8 oz of malt liquor (7% alcohol), 5 oz of wine (12% alcohol), or 1.5 oz of distilled spirits (40% alcohol; 80 proof). The current Dietary Guidelines for Americans recommend not to exceed 1 drink a day for women or 2 drinks a day for men. Any alcohol can be toxic if ingested in large enough quantities. While alcohol toxicity most commonly results from the abuse of ethanol ("drinking alcohol") found in alcoholic beverages, it can also result from the inge Continue reading >>

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  1. Betty2003

    Not a very lady-like subject, but need to ask anyway. I notice during induction (probably in week 2) that my urine started to have a horrible smell. I thought I read somewhere that that is a sign of ketosis--is it? I've looked for test sticks at Meijer, K-mart, and the grocery store but can't find them anywhere. I do notice that I drop pounds when the smell is there--what do you think? Is that my indicator of ketosis? Thanks!

  2. pokey one

    I've noticed the same thing. And that constant metallic taste in my mouth lets me know I'm in ketosis, too.
    The strips are usually back with the pharmacist, not out on the shelves. So you just have to ask for ketone testing strips. (I guess they're expensive enough and the box is small enough that they could easily be shoplifted.)
    If you do get the strips, don't worry about the shade of pink to purple--even the slightest pink signals ketosis. I was very happy to see mine change from being beige for a few days to pink .
    HTH

  3. tofi

    In Canada, the stix are with the supplies for diabetics. They used to be behind the pharmacy counter but are now out on the shelves in Shoppers' Drug Marts. They cost about $7.50 Canandian. I hear that Wal-Mart in the US has them. The most common brand name is Ketostix by Bayer.
    And the interesting odour is less expensive. If you are losing, why bother with the stix?

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