Medications That Cause Metabolic Acidosis

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What is BASAL METABOLIC RATE? What does BASAL METABOLIC RATE mean? BASAL METABOLIC RATE meaning - BASAL METABOLIC RATE definition - BASAL METABOLIC RATE explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Basal metabolic rate (BMR) is the minimal rate of energy expenditure per unit time by endothermic animals at rest. It is reported in energy units per unit time ranging from watt (joule/second) to ml O2/min or joule per hour per kg body mass J/(hkg)). Proper measurement requires a strict set of criteria be met. These criteria include being in a physically and psychologically undisturbed state, in a thermally neutral environment, while in the post-absorptive state (i.e., not actively digesting food). In bradymetabolic animals, such as fish and reptiles, the equivalent term standard metabolic rate (SMR) is used. It follows the same criteria as BMR, but requires the documentation of the temperature at which the metabolic rate was measured. This makes BMR a variant of standard metabolic rate measurement that excludes the temperature data, a practice that has led to problems in defining "standard" rates of metabolism for many mamma

Drug-induced Metabolic Acidosis

SummaryDrug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal anion gap (e.g. drug-induced renal tubular acidosis) or an elevated anion gap (e.g. drug-induced lactic acidosis or pyroglutamic acidosis). This review describes the drugs that can cause or contribute to metabolic acidosis during therapeutic use, the mechanisms by which this occurs, and how they may be identified in practice. aNeurointensive Care Unit, St George's University Hospitals NHS Foundation Trust bClinical Pharmacology, St George's University of London, London, UK Correspondence to Andrew W. Hitchings, Senior Lecturer in Clinical Pharmacology and Consultant in Neurointensive Care, St George's University Hospitals NHS Foundation Trust and St George's University of London, Cranmer Terrace, London SW17 0RE, UK. Tel: +44 20 8725 5380; e-mail: [email protected] Editor: R E Ferner, MSc, MD, FRCP, Director of the WestMidlands Centre for Adverse Drug Reaction Reporting and Consultant Physician at City Hospital, Birmingham, UK. Assistant Editor: Mr C Anton, MA, MEng. Editorial Board: Australia: Dr M Kennedy, Professor G M Shenfie Continue reading >>

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  1. Rhapsody

    Why does citric acid knock some people out of ketosis???
    Does it have anything to do with the KREB cycle?

  2. Sheesh

    Citric acid plays a key part in the Kreb Cycle (aka the "Citric Acid Cycle"), simply because it the 6-carbon molecule that pretty much starts the cycle is indeed Citric Acid (acetyl-coa combines with oxaloacetate to form the citric acid, and this is the first step of the cycle).
    But, no, it's not going to knock you out of ketosis.

  3. spike1205

    Sheesh--from what ive read (or atleast rememebr) citric acid does/can knock you out of ketosis. I dont know the research on it and tend to believe it is more likely other ingredients in foods containing citric acid (ie aspartame in diet sodas) but i have read repeatedly that citric acid does and can --Rhaps--i sont have a clue how

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Quickest Way to Flush Your BODY CLEAN of TOXINS. Help PREVENTS CANCER & REMOVE TOXIN from LIVER, COLON. On any given day, you may be exposed to any number of the 80,000-plus industrial chemicals in use today. Another 1,000 chemicals or so are introduced every year, according to Brenda Watson, a certified nutritional consultant and author of The Detox Strategy. These toxic substances lurk everywherein the air, water, household cleaners, perfumes, food and childrens toys. While the process of detox has its critics, natural health professionals extol its benefits for helping your body to expel toxins. Step 1 Reduce the amount of toxins you take in on a daily basis. Its self-defeating to do a detox if youre still taking in a significant amount of toxins, points out Peter Bennett, a naturopathic doctor and author of The Purification Plan. Switch to organic foods and beverages and drink filtered or distilled water. Avoid using products that contain toxins, such as household cleaners, inorganic cosmetics and perfumes, and avoid exposure to cigarette smoke or other airborne chemicals. Step 2 Eat about 30 to 40 grams of fiber daily. As Ann Louise Gittleman puts it in her book The Fast Track

Metabolic Acidosis Due To Drugs And Toxins Acidosis due to Drugs and Toxins Metabolic Acidosis due to Drugs and Toxins Several drugs and toxins have been implicated as direct or indirect causes of a high-anion gap metabolic acidosis (HAGMA). A consideration of these drugs needs to be included in an differential diagnosis of a HAGMA. The three most common ones to consider are methanol, ethylene glycol and salicylates. Other toxins which can cause acidosis are isopropyl alcohol and butoxyethanol. Toluene also causes an acidosis and the anion gap may be normal or elevated. * Initially no acid-base disorder due to long latent period while methanol is metabolised * Later, typically develop a high anion gap metabolic acidosis -due to formic acid * May also develop a respiratory acidosis secondary to CNS depression (with depression of respiratory centre and/or airway obstruction) * May occasionally present with normal anion gap acidosis if smaller ingestion * If patient is an alcoholic, there may other types of acidosis present as well (eg alcoholic ketoacidosis, starvation ketoacidosis, lactic acidosis, respiratory acidosis due aspiration, respiratory alkalosis due chronic liver disease.) Principles of Treatmen Continue reading >>

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  1. Victoria W(619)

    Raspberry ketone?

    Hi everyone,
    Just wondered if anyone has tried raspberry ketones. I have seen them advertised everywhere and wondered if they worked? Risky? Any side effects?

  2. Ayesha P(3)

    Hi I have been on raspberry ketone for 3 weeks and lost nothing. I think it's a load of crap. Spent £45 on it too got it shipped from america

  3. Victoria W(619)

    Oh so not the miracle they make out to be? I knew they sounded too good to be true. Let me know how you get on

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

Drug-induced Metabolic Acidosis

Pharmacologically-Induced Metabolic Acidosis. Liamis G et al. Drug Saf 2010 May 1; 33:371-391. This somewhat wordy article is a complete review of drug-induced metabolic acidosis, and well worth reading for those interested in expanding their knowledge beyond the mnemonic MUDPILES or reviewing the 4 types of renal tubular acidosis. There is so much detail here that the paper is impossible to summarize, but here are some of its clinical pearls: Most of the patients who develop metformin-associated lactic acidosis had been taking the drug despite have a contraindication to its use, such as renal insufficiency or severe underlying disease. Antiviral therapy, especially nucleotide reverse transcriptase inhibitors, have been associated with life-threatening metabolic acidosis. Drugs implicated most often include didanosine, stavudine, and zidovudine. Linezolid impairs mitochondrial function and can cause metabolic acidosis, usually after prolonged therapy. The occurrence of metabolic acidosis in patients on propofol may herald onset of propofol infusion syndrome , which has a mortality rate of greater than 80%. Occult laxative abuse is on the differential diagnosis for a patient with u Continue reading >>

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  1. Cragvis

    I started keto when I was 250, now a month later I am 258.
    I dont get it. I have been sticking to a very strict diet, literally, this is all I eat every day:
    2 burger patties made from ground beef 70% lean (fattiest i could find)
    2 eggs
    some cheese on top (each egg gets 2 slices of cheese, each slice is about 2 inch squares of cheddar cheese)
    1 avocado
    1 cup of broccoli
    Snacks: (1 of any of the following per day, not all snacks every day)
    4 strips of bacon.
    some pork rinds usually 1 serving (9 pieces) no carbs even in them.
    protein shake, 0 sugar 3 carb protien mix (1 cup) + about 3 tbsp heavy cream and a cup of almond milk comes out to be about 8 or 9 carbs
    At work i have 1 cup of coffee a day with some splenda in it, usually 3 packets and some coffeemate half and half. The rest of the day I drink water.
    So each day I am getting at least less than 20g carbs a day but no more than 50 for sure, defiantly less than 50. yet, this whole month ive been gaining weight, and I dont even work out so my muscles cant be growing on their own.
    wat is going on? :/

  2. fitfii

    Try dumping the protein powder and the splenda. If you don't work out, you don't need that much protein, and it might be that it gets converted to sugar, knocking you out of ketosis. Splenda also halts weight loss for most people (me included, it makes you overeat).
    Try to eat clean for a week - nothing your caveman ancestor granny wouldn't eat. Keep the bacon, beef, eggs, avocado, up the broccoli, keep the cream and almond milk. Include some fried chicken legs (place chicken into ovenproof tin, rub with olive oil, salt, pepper, some lemon juice, put it into the preheated oven at 180°C (~350F) for 20-30 minutes until sticking a fork in it does not produce red juice anymore).
    Do you drink any alcohol?

  3. bawlz_

    Keto - nothing your caveman ancestor granny wouldn't eat.
    I. love. it

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    Pharmacologically-Induced Metabolic Acidosis. Liamis G et al. Drug Saf 2010 May 1; 33:371-391. This somewhat wordy article is a complete review of drug-induced metabolic acidosis, and well worth reading for those interested in expanding their knowledge beyond the mnemonic MUDPILES or reviewing the 4 types of renal tubular acidosis. There is so much detail here that the paper is impossible to summarize, but here are some of its clinical pearls: M ...

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