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Low Carb Diet Insulin Resistance

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What is CARBOHYDRATE METABOLISM? What does CARBOHYDRATE METABOLISM mean? CARBOHYDRATE METABOLISM meaning - CARBOHYDRATE METABOLISM definition - CARBOHYDRATE METABOLISM explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Carbohydrate metabolism denotes the various biochemical processes responsible for the formation, breakdown and interconversion of carbohydrates in living organisms. The most important carbohydrate is glucose, a simple sugar (monosaccharide) that is metabolized by nearly all known organisms. Glucose and other carbohydrates are part of a wide variety of metabolic pathways across species: plants synthesize carbohydrates from carbon dioxide and water by photosynthesis, storing the absorbed energy internally, often in the form of starch or lipids. Plant components are consumed by animals and fungi, and used as fuel for cellular respiration. Oxidation of one gram of carbohydrate yields approximately 4 kcal of energy, while the oxidation of one gram of lipids yields about 9 kcal. Energy obtained from metabolism (e.g., oxidation of glucose) is usually stored temporarily within cells in the form of ATP. Organisms capabl

Improvements In Glucose Metabolism And Insulin Sensitivity With A Low-carbohydrate Diet In Obese Patients With Type 2 Diabetes.

Improvements in glucose metabolism and insulin sensitivity with a low-carbohydrate diet in obese patients with type 2 diabetes. Endocrine, Diabetes and Research Centre, Wellington Hospital, Wellington, New Zealand. [email protected] The optimal diet for weight loss in type 2 diabetes remains controversial. This study examined a low-carbohydrate, high-fat diet with detailed physiological assessments of insulin sensitivity, glycemic control, and risk factors for cardiovascular disease. Fourteen obese patients (body mass index [BMI] 40.6 4.9 kg/m(2)) with type 2 diabetes were recruited for an "Atkins"-type low-carbohydrate diet. Measurements were made at 0, 12, and 24 weeks of weight, insulin sensitivity, HbA1c, lipids, and blood pressure. Twelve completers lost a mean of 9.7 1.8 kg over 24 weeks attributable to a major reduction in carbohydrates and resultant reduction in total energy intake. Glycemic control significantly improved (HbA1c -1.1 0.25%) with reductions in hypoglycemic medication. Fasting glucose, homeostasis model assessment (HOMA), and area under the curve (AUC) glucose (intravenous glucose tolerance test [IVGTT]) were significantly reduced by week 12 ( p < 0. Continue reading >>

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  1. lucid

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    Hey guys (and ladies!),
    I'm a 28 yo male.
    Weight: 235
    BodyFat%: 12%
    IGF-1: 231 ng/ml
    Insulin (Fasting): 7.6 uIU/ml
    Having bad cholesterol, I decided to switch to a very low-carb diet. I was <50g carb/day and was deep in ketosis for about 4 months. Big changes happened. Triglycerides went from 300-400 down to 80-95 (-70%). HDL went from 26->40 (+55%). LDL+VLDL went from 136 -> 130 (-4%). Lipid profiles (so far as I can tell), don't change that rapidly so I expect the results to improve over the next year.
    For the first time in my life, I have blood work that indicates I'm not at risk for diabetes or heart disease. In the "before" era, I was in OK shape (16% bf). I didnt drink sodas, eat dessert or candy etc. I ate normal 'balanced' meals that included rice, whole grain etc.. So I maybe I just had bad genetics, maybe thats why my bloodwork sucked. WELL, nurture > nature.
    Now there are some downsides to being in ketosis:
    1. Fatigue: You muscles lose all their glycogen stores and replace them with triacylglycerol - triacylglycerol isn't as oxygen efficient in its metabolism. This means that you can't excercise close to your aerobic threshhold for very long at all.
    2. Insulin Resistence: When you first start going into ketosis, your fasting blood glucose is AMAZING. My fasting glucose went into the high seventies. However, prolonged ketosis causes insulin resistence & increased fasting blood glucose. By 4 months in my blood glucose was mid/high nineties. This isn't normal insulin resistence -> it exists to route all existing glucose to the brain instead of the muscles and is reversed once you start consuming carbs (oddly enough).
    For these reasons, I have stopped trying to be in ketosis and instead am doing just a low carb diet. Still no grains, no sugar (except that found in fruit), and few starchy veggies. What's the difference you might ask? Well I have added things like beans and fruit back into my diet. I'll post results in a month or two and we will see how that impacts the above results.
    As I was reading up on ketosis and its effects. I found that the ketogenic diet was invented a long time ago (100 years) to treat epilepsy. The reason that it helps with epilepsy is that the brain starts consuming ketone bodies instead of glucose when in ketosis. This prevents seizures! So as a result lots of epileptic children were put on ketogenic diets. And... they found that when kids were put on ketogenic diets their height and weight velocity (increase / year) was very significantly slowed. This will start sounding very familiar to you dwarf mice fans -- Now guess what was happening...? Their IGF-1 levels dropped significantly from being in ketosis and it became evident that their growth was stunted. (Can provided references)
    Ketosis causes IGF-1 to drop because a ketogenic diet isn't just a low carb diet, its a HIGH FAT DIET! Don't think 'Atkins' where you are eating steak and veggies. You have to control you protien intake as well (though it should be up a little bit). In a ketogenic diet, 75+% of your calories are going to come from fat! It might be starting to dawn on you how ludicous it felt: I was eating cheesy eggs & bacon to improve my risk for heart disease!!!! The reason that I mention that the ketogenic diet is really a high fat diet is because fat is the only macro-nutrient that doesn't stimulate insulin. Carbs stimulate insulin and to a lesser exent protien does as well. The picture should be pretty clear at this point how ketosis should impact IGF-1: High fat, medium protien and low carbs should radically lower the IGF-1 levels. And (as I'm hoping this audience already knows), IGF-1 levels dramatically effect aging in almost every animal its been studied in!
    Now on to my question!!!
    So I (kind of) screwed up. I didn't get a 'before' IGF-1 test. If you are going to do the same protocol, do this one thing. Get a complete 'before' test before you start - I was too axious to start, and boy I wish I had gotten it done. So here is my predicament:
    I don't have a baseline for my before 'IGF-1', now as a secondary problem I went out of ketosis and switched to just being low-carb about a 3 days before my blood work.... I know, I know. Ughhhh. To make matters worse, the baseline for IGF-1 is very ambiguous and every single source that I have read has a different reference interval for IGF-1 for my age group. Some show its sex dependent some show its not. So are my IGF-1 and/or insulin levels low?
    Anyways, thanks for reading. Please post if you found this interesting, would like to know more or think you can help answer my questions!!!

  2. Chupo

    Click HERE to rent this advertising spot for NUTRITION to support LongeCity (this will replace the google ad above).

  3. Pour_la_Science

    235 lbs (106 kg) for 12% of fat Are you a body builder?

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Low Carb High Fat Diet or High Carb Diet - Which Causes Insulin Resistance: https://youtu.be/NbU8RIBRvjI Diabetes: https://www.youtube.com/playlist?list... -------------------------------------------------------------------------------------- Mentioned Book - Video - Website / Shout Outs -------------------------------------------------------------------------------------- DR GREGER'S BOOK - HOW NOT TO DIE US Amazon Book How Not to Die: http://amzn.to/2g67bmK UK Amazon Book How Not to Die: http://amzn.to/2grlYwy http://nutritionfacts.org/book/ Dr Greger's YouTube Channel https://www.youtube.com/user/Nutritio... Dr Gregers website http://nutritionfacts.org/ This is for educational purposes only and no copyright infringement is intended. ===================================================== Thanx for watching this Video!! Please do SUBSCRIBE & LIKE so you can help my new channel to GROW! & share this with friends All your support means the world to me! Till next time Keep on Keepin On & Just Go Do It Already ===================================================== STATS Name: Jon Anthony Age: 45 Height: 6:3" / 191cm Starting Weight: 151.8kg / 335lbs / (BMI) 41.9 Current Weight: 111.0k

Increased Insulin Resistance With A Low Carb Diet?

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Increased Insulin Resistance with a low carb diet? Bebo321 Family member Well-Known Member @azure @Brunneria @tim2000s , I would be interested to hear your thoughts on an observation of increased insulin resistance with a very low carb/keto diet. I was discussing this topic recently with somebody with T1D (we tried a food fast together over a number of days) They noticed that coming back out of the fast, their insulin requirements had increased fairly significantly in order to manage any carb they ate (the increased requirements only lasted a few days). Interestingly, their basal had remained exactly the same throughout the fast however and blood glucose levels had remained level. This would suggest that their 'insulin resistance' hadn't actually changed at all. What we considered had perhaps happened was that the body had become so effective at burning ketones and generating its own glucose requirements (gluconeogenesis), that once carbs were re-introduced, the body was fairly 'ambivalent' to it - after all, it had everything it needed to fuel itself perfectly w Continue reading >>

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  1. ICNAnnie2

    I've been reading your recent dining review and am really enjoying it. However, I must admit even the mention of some of the foods you consumed made my damaged-by-IC bladder cringe!
    Are you doing what I did? Are you denying that diet affects how you feel? Are you thinking that you are in so much discomfort/pain it doesn't seem to matter what you eat or drink? I did that when IC first struck me and lots of others do it, too. Diet denial is common. What you MUST realize is that right now your bladder is so very inflammed and irritated you can't distinguish between foods that are ok and those that hurt you. The only way to get your bladder to calm down is to CAREFULLY follow the diet and eat only foods in the "usually ok" column (follow the IC Diet you can find on the IC Network). Some people say they begin feeling better after a week or so on the diet. For many of us, it takes 8-12 weeks of following it before the bladder begins to calm. When that finally happens you can then begin adding in new foods and you WILL be able to tell if a food is bothering your bladder or not.
    You stated yesterday on another board you consumed tomato soup, grilled cheese and smoked porter. OUCH, OUCH, OUCH!!!!!!!!!!!!!!!!!!!!!!! Ok, the grilled cheese would be alright as long as you used mild American or mozzarella cheese and white bread with no soy flour or preservatives in it. The other items are real bladder burners!!! Also, since you have a cold, watch out for decongestants as they can really irritate the bladder. Many of us with IC are ok with using Mucinex and antihistamines are usually ok (in fact antihistamines are often used, in combination with other meds, to treat IC).
    PLEASE, PLEASE, PLEASE........begin taking care of yourself and start the diet today. IC is a serious disease. It can be one of the most painful diseases known to humankind. Did you know that severe IC pain has been evaluated as being as painful as end-stage cancer? Also, please involve your DH and make him a part of your health care team. He needs to accompany you to some of your appointments and learn as much as he can about your condition so he can better understand what you are going through, give you the support you need and better cope with living with IC. You two are a team. IC will impact every aspect of your life. You are in this journey together.
    With IC, the protective inner layer of the bladder is damaged allowing all the toxic substances passing through to come into direct contact with nerve cells and with the delicate bladder tissue. Now, if you had a wound like that on the surface of your skin and you poured lemon juice, vinegar or alcohol or paprika or chili powder (or any other acid or strong spice) on it every single day, what would that do to the wound? Obviously, it would irritate it and make it more difficult for that wound to heal. Well, the same applies to your bladder. It is wounded and, when you continue to consume bladder-irritating substances, those irritants pour over that injured tissue and make matters worse.
    IC is a monster of a disease. I know how very, VERY difficult it is to give up all that is required. You have to count on your doctors to help you, but you also have to do all you can to help yourself. There is life with IC and it can be a good one. It will be different from what you have known, but it still can be good. The IC Network support forum is there with wonderful experienced ICers who can offer tons of helpful tips to cope with all aspects of this disease.
    I'm sure your dear friends here will also offer invaluable support to you as you travel this difficult road. Good luck.........and PLEASE take care of yourself.

  2. Tink rules

    Awwwww.. Bendy....
    Why are we such sisters in all of this semi misery???
    I keep getting kidney stones and I'm afraid that it's more...
    I can tell you that the bathrooms by the Grand Floridian Cafe do have double ply TP... (I was quite impressed with that...)
    Hugs for feeling better!!!

  3. LilyLake

    Hi Brenda. I thought I'd pop in here and give some support, and commiserate. We've chatted briefly in the past. I'm a fellow figure skating fan. I love your dining reviews. Today I read your Halloween sushi review and really enjoyed it. I also read some of the Boca Ratan (sp?) trip report. That's quite an anniversary gift. I just had my 25th anniversary at my job, and I got to select from a list of gifts which were in the $200-300 range. (Yes, I looked some of them up on the internet to see how much they cost.) I have a very nice globe now. I'm sorry I'm such a lurker and rarely say anything. I guess my name should be LilyLurk.
    While I don't have a bladder problem, I am having a health problem that I'm trying to clear up with some medication and a very limited diet. I'm fighting yeast, which thrive on sugar, so I'm eating a very low-carb diet, in order to keep sugar out of my digestive system. I also have to avoid all yeasts and molds. So I can't have anything with vinegar in it, or any cheese. I'm also avoiding the lactose in dairy products, which also means no cheese - even the not-so-moldy ones. I've been doing this for 2-1/2 weeks. So essentially what I'm eating are meat and vegetables, but I can't have smoked or cured meats. So no bacon, ham, or smoked salmon. I also eat nuts, which I know you don't eat.
    I started with a garden-variety low-carb diet for a week before I started the meds. and really limited diet. In 3-1/2 weeks I've lost about 8 pounds. Okay - I can stand to lose a little weight, but now I'm within 5 pounds of what I consider to be my ideal weight. And I'm not trying to lose weight, or just allow myself to go hungry. I'm eating a lot. I'm watching my ketosis levels with ketostix, and I'm definitely in ketosis. This means I'm burning fat, and is the reason low-carb diets work. So I have a question for some of you on this thread who have done this diet for awhile: do you have a problem with losing too much weight? I haven't looked at the IC website to see what the approved foods are, but I'm wondering what's on there that you can use to keep your weight where you want it. I need to go another 1-1/2 weeks before I start trying to add things back in.
    I've been enjoying reading your latest dining review over the last 2-1/2 weeks, while I try to figure out which meat I'm going to eat next. It does get tiresome. I did make some spaghetti last week. It was essentially ground turkey, onions, garlic, some herbs and canned crushed tomatoes. I just didn't eat it with any noodles or cheese. Boy, did my body not appreciate that dinner! And I had to be up at the high school that evening for a boys hockey meeting. I haven't had any canned tomatoes since.
    Some of the meals I eat are really good, and afterwards I think "this isn't so bad." This lasts until the next time I start to get hungry and have to have some other plain meat and vegetable meal and I want to commit hara-kiri. I have to remind myself that it's for the greater good, and I'm going to stick with it.
    So Brenda, this is new to me, too. Feel free to PM me, if you'd like. I'm depressed for you. I know how much you love food and drinks. Of course, since I'm avoiding yeast, I can't have alcohol, either. I'm not a big drinker, but I do enjoy a nice glass of wine.
    Oh, something else. Apparently my bladder got thrown-off by the anti-yeast medication I'm taking. I guess my bladder is used to having yeast in there and didn't appreciate the change. So I developed a mild bladder infection. Now, antibiotics are probably how I got into this mess, so I wasn't about to try to get an antibiotic for this. What to do? Cranberries! But cranberry juice cocktail is loaded with sugar and I'm not using artificial sweeteners, either. So on Halloween night as you were getting ready to enjoy your sushi dinner, I had the Mr. stop at the grocery store so I could pick up a bag of cranberries from the produce section. That's right - I chomped on plain, raw cranberries. They really weren't as bad as I was expecting. And they did help. I had to eat them for the first couple of weeks, but this week I haven't needed them.

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In this Low Carb Chicken and Salad Recipe I make an easy Low Carb Chicken and Salad in Minutes that any one can make with very little cooking skills. This is great for low carb dieting and has all natural healthy ingredients. If you guys want to see more healthy recipes like this to help with your meal prep please comment below. I hope you guys enjoy the Video and it helps with your Health and Fitness Journey and to Achieve your Goals. Please remember to subscribe here for more videos weekly. https://www.youtube.com/user/justaddm... Also check out or Supplement Website for over 6000 brand name supplements at wholesale here:http://www.justaddmuscle.com/ and use code youtube for a 10% discount on your entire order. Facebook:https://www.facebook.com/JustAddMuscl... Twitter:https://twitter.com/justaddmuscle Instagram http://instagram.com/justaddmuscle

If Low Carb Eating Is So Effective, Why Are People Still Overweight?

If low carb eating is so effective, why are people still overweight? I find myself getting asked this question, or some variant of this question, with increasing frequency as I speak and write about the Alternative Hypothesis I find most compelling surrounding obesity and chronic disease. One implication of the Alternative Hypothesis, as you probably understand by now if youve been reading this blog, is that many carbohydrates, especially if consumed at the levels most Americans consume them, promote fat gain. In other words, overweight people are not the lazy, constantly grazing, weak-willed individuals many in the mainstream have led us to believe. They just eat the wrong foods (rather than simply too much food). Remember, I was one of those doctors in the mainstream once upon a time. While I always tried (and hopefully succeeded most of the time) to treat overweight patients with respect, I silently judged them. Why cant you just eat less and exercise more? Only when I realized, despite my diet which rigorously adhered to formal recommendations and my 3 to 4 hours of exercise per day, that even I was getting too fat for comfort, did I begin to question the Conventional Wisdom o Continue reading >>

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  1. Shakim28

    I started on Monday, I've been eating less than 1500 calories a day and I have been hitting all my macros. I haven't had a day where I went over 5 grams of net carbs. The flu hasn't hit and I don't think I have keto breath or keto pee yet! Someone please explain how I am supposed to know?

  2. DownhillYardSale

    Did you just start?
    Did you eat less than 100g of carbs in the past 24 hours?
    Yes?
    Are you dead?
    No?
    Congratulations, you are in ketosis.
    Something that is interesting here is that there are 2 definitions for what ketosis is on this subreddit.
    Clinically ketosis is having beta-hydroxybutyrate levels in your blood over 0.2 mmol/L.
    Few here test that so we don't technically know whether they are in ketosis or not.
    The ketosis most people refer to here is that their body is primarily burning FAT for fuel instead of GLUCOSE.
    In this sense... if you eat 20g of carbs, you'll be in ketosis.
    Without measuring your blood we cannot state emphatically/clinically what your state of ketosis is.

  3. bidnow

    You trust us and save your money from not buying ketostix and buy bacon or Kerrygold butter instead.

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