Lactic Acidosis In Dka

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Prevalence And Significance Of Lactic Acidosis In Diabetic Ketoacidosis

The prevalence and clinical significance of lactic acidosis in diabetic ketoacidosis (DKA) are understudied. The objective of this study was to determine the prevalence of lactic acidosis in DKA and its association with intensive care unit (ICU) length of stay (LOS) and mortality.Retrospective, observational study of patients with DKA presenting to the emergency department of an urban tertiary care hospital between January 2004 and June 2008.Sixty-eight patients with DKA who presented to the emergency department were included in the analysis. Of 68 patients, 46 (68%) had lactic acidosis (lactate, >2.5 mmol/L), and 27 (40%) of 68 had a high lactate (>4 mmol/L). The median lactate was 3.5 mmol/L (interquartile range, 3.32-4.12). There was no association between lactate and ICU LOS in a multivariable model controlling for Acute Physiology and Chronic Health Evaluation II, glucose, and creatinine. Lactate correlated negatively with blood pressure (r = -0.44; P < .001) and positively with glucose (r = 0.34; P = .004).Lactic acidosis is more common in DKA than traditionally appreciated and is not associated with increased ICU LOS or mortality. The positive correlation of lactate with gl Continue reading >>

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  1. driven1

    OK.... I'm a keto newbie, on Day 9 of the 12 day start up. As and aside, I feel great and am loving the food choices.
    ANYWAY... I have a girl friend who is an RN (and a very good one), who has cautioned me that ketones are 'hard on the kidneys'.
    Now, I love my GF to death, and I know that she means only the best, but I have very little confidence in the conventional medical community. After all, this is an industry that makes it's money from people being sick...
    My research has turned up that ketones are NOT damaging to the kidneys. On the contrary, the kidney uses ketones as a preferred fuel source when they can get them. The heart and brain as well as other major organs prefer them too...
    Seems as though the confusion is with the fact that a lot of medical professionals consider the excessive protein while on a keto diet damaging to the kidneys. I have also found research that dispels this... showing that only individuals who already have compromised kidney functions MIGHT have a problem with excess protein in the diet.
    I'm looking for comments from those who are experienced with the keto lifestyle. What do you know??

  2. titebuoy

    excessive dietary protein causes your kidneys to work harder to remove excess nitrogen. however, the keto is a high fat diet, not a high protein diet so i wouldnt be worried about it unless your macros are out of wack. some people have trouble with foamy urine on the diet, but most people dont experience kidney trouble on keto.

  3. stew9812

    I'm new to this too.
    I think what they teach the doctors/nurses is whats best for the general public. (people that don't work out, and don't necessarily get enough water ect..) So they may not always have the best answers for people like us.
    I would say to just drink plenty of water, and you will be fine.
    Just my opinion here, but like you say there is plenty of people who have done this diet with no bad side effects, and there is plenty of research supporting this to be a healthy diet as well.
    just my .02

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What is SERUM ALBUMIN? What does SERUM ALBUMIN mean? SERUM ALBUMIN meaning, definition & explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood. Human serum albumin is encoded by the ALB gene. Other mammalian forms, such as bovine serum albumin, are chemically similar. Serum albumin is produced by the liver, occurs dissolved in blood plasma and is the most abundant blood protein in mammals. Albumin is essential for maintaining the oncotic pressure needed for proper distribution of body fluids between blood vessels and body tissues; without albumin, the high pressure in the blood vessels would force more fluids out into the tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids. Too much or too little circulating serum albumin may be harmful. Albumin in the urine usually denotes the presence of kidney disease. Occasionally albumin appears in the urine of normal persons following long standing (postural

Increased Serum D-lactate Associated With Diabetic Ketoacidosis

Get rights and content We hypothesized that serum d-lactate may be increased in vivo in diabetes mellitus as a result of increased glucose flux through the glyoxalase pathway and/or via hepatic ketone metabolism. Levels of d-lactate and related metabolic intermediates were measured in 30 cats with spontaneous diabetes mellitus and in one ketoacidotic nondiabetic cat. Serum d-lactate was significantly (P = .0051) elevated in cats with ketoacidosis (337.2 70.2 mol/L) as compared with nonketoacidotic diabetic (140.3 58.8) and control (25.0 + 6.5) cats. Two nonketoacidotic cats also had high levels of d-lactate. There was a significant linear correlation (r = .684, P = .0001) between d-lactate and -hydroxybutyrate concentrations. Serum d-lactate did not correlate with serum glucose (r = .078, P = .6825), and in vitro erythrocyte d-lactate formation did not increase in the presence of hyperglycemia. These data suggest that hepatic ketone metabolism, rather than hyperglycemia, may be a major source of serum d-lactate in diabetics. Continue reading >>

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  1. yshahin

    I am wondering what are the effects you have seen of eating carbs after being fat adapted?
    I have been on Keto for 5 weeks and cravings have stopped. I went for a KFC breaded dinner and saw some side effects of the carbs.
    1) Dehydration
    2) Little Craving
    3) Bloated


  2. Jeffryan

    Hard to sleep
    Get dizzy two days after running out of gylcogen so back to the keto flu.
    Lots of guilt lol

  3. BodyInBeta

    I'm too afraid to find out.

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https://www.facebook.com/drinkhealthy... - Do you want to learn how to get rid of lactic acid as an athlete, and start recovering quicker with more energy? Learn how to reduce lactic acid symptoms and increase your performance. Getting rid of lactic acid may be easier than you have imagined. Many professional athletes know the importance of eliminating lactic acid so they can recover quicker and perform at an optimal level. Start flushing out that lactic acid today! Many people suffer from lactic acidosis symptoms and are rigorously searching for a lactic acid treatment. More and more athletes are searching for solutions on how to get rid of lactic acid. In this video you will learn what a professional football player from the Seattle Seahawks is using to eliminate lactic acid after his workouts, practices, and NFL games. Learn how to make lactic acid a symptom of the past. Begin your journey to faster recovery today. See what the pro's are using to reduce lactic acid, recover quicker, and have more energy. Uncertain of what lactic is? Here is the definition https://en.wikipedia.org/wiki/Lactic_... Contact me for more information on getting rid of lactic acid FB: http://www.faceboo

Lactic Acidosis: Background, Etiology, Epidemiology

Author: Kyle J Gunnerson, MD; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, MCCM more... In basic terms, lactic acid is the normal endpoint of the anaerobic breakdown of glucose in the tissues. The lactate exits the cells and is transported to the liver, where it is oxidized back to pyruvate and ultimately converted to glucose via the Cori cycle. In the setting of decreased tissue oxygenation, lactic acid is produced as the anaerobic cycle is utilized for energy production. With a persistent oxygen debt and overwhelming of the body's buffering abilities (whether from chronic dysfunction or excessive production), lactic acidosis ensues. [ 1 , 2 ] (See Etiology.) Lactic acid exists in 2 optical isomeric forms, L-lactate and D-lactate. L-lactate is the most commonly measured level, as it is the only form produced in human metabolism. Its excess represents increased anaerobic metabolism due to tissue hypoperfusion. (See Workup.) D-lactate is a byproduct of bacterial metabolism and may accumulate in patients with short-gut syndrome or in those with a history of gastric bypass or small-bowel resection. [ 3 ] By the turn of the 20th century, many physicians recognized that patien Continue reading >>

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  1. cfine

    I have noticed that there are a few more people besides me who have this horrible disease. IC actually derailed my LCing back years ago before.
    I'm curious as to what foods makes you have pain on LC? I thought this thread might help us. I also have vestibulitis and pelvic floor dysfunction...fun times
    My triggers are :
    processed meats
    too many nuts of any kind(peanut butter is the worst for me)
    artificial sweeteners(I can do little amounts)
    I still eat most of these foods, I just try to rotate them and eat them sparingly. I still have varying amounts of pain most every day. The foods that don't trigger pain are all of the foods that you can't eat on LC, like bread, potatoes, rice, oats. I am doing ok with it though, and LC helps me keep my diabetes in check.
    Also I don't take any meds for my IC. For about five years I stayed in a fog from all of the meds my doctor had me on. I decided that I didn't want to live that way and quit them all cold turkey. They weren't really helping me all that much anyway.

  2. princessmommy

    I haven't been offically DX'd with IC but I have fibromylgia and my symptoms are spot on from what i've read/heard. I've noticed if I don't drink a lot of water my bladder gets very irritated, as well as if I eat acidic foods like tomatoes and to much coffee. All things I Love lol. I plan on talking to my Dr about it next appt and see what he says. I've gone to the Dr two times thinking it was a uti and it not be.

  3. marriedtothearmy

    I've actually had far less flares since starting low carb. I did gain about 20 lbs after being diagnosed last year because, as you said, it seems at first that all the carb things are the friendliest to the bladder.
    Based on the fact that this seems to work better for me, I've come to the conclusion that processed foods and my bladder just don't agree. I also have to stay away from all artificial sweeteners, all fruits and anything with any type of acidic level to it.
    I can handle some onions as long as they're cooked and the same seems to go for tomatoes. My list of foods that I can't eat is MUCH longer than what I can but doing low carb has been relatively easy with the restrictions. The only thing that frustrates me is the large number of recipes with artificial sweeteners (and usually a LOT of them!). But my husband is also a chef so that helps.
    I can get away with drinking unsweet tea (nothing added) but that seems to be the only drink that doesn't bother me other than water. For a while, I had to even be careful about the types of bottled water I was drinking but that seems to have gotten better since I changed my diet.
    It took me nearly ten years to get diagnosed with IC. It was such a relief to finally know what it was and that I was not really getting UTIs one right after the other for all of those years. At first, they tried me with all the medications (Elmiron, Amitrypline (sp?) and a few others). They caused MAJOR side effects for me and I really didn't see any improvement so I stopped them all. I've been controlling it with diet ever since.
    I was recently prescribed a TENS unit and I love it for IC! I also use the instills at home if it gets really bad. But honestly I have to be in a LOT of pain to put myself through that one!

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