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Lactic Acidosis Guidelines

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Lactic Acidosis Treatment & Management

Approach Considerations Treatment is directed towards correcting the underlying cause of lactic acidosis and optimizing tissue oxygen delivery. The former is addressed by various therapies, including administration of appropriate antibiotics, surgical drainage and debridement of a septic focus, chemotherapy of malignant disorders, discontinuation of causative drugs, and dietary modification in certain types of congenital lactate acidosis. Cardiovascular collapse secondary to hypovolemia or sepsis should be treated with fluid replacement. Both crystalloids and colloids can restore intravascular volume, but hydroxyethyl starch solutions should be avoided owing to increased mortality. [21] Excessive normal saline administration can cause a nongap metabolic acidosis due to hyperchloremia, which has been associated with increased acute kidney injury. [32] Balanced salt solutions such as Ringer lactate and Plasma-Lyte will not cause a nongap metabolic acidosis and may reduce the need for renal replacement therapy; however, these can cause a metabolic alkalosis. [33] No randomized, controlled trial has yet established the safest and most effective crystalloid. If a colloid is indicated, a Continue reading >>

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Popular Questions

  1. LIFEISWAITING

    I heard some people do it every 2 weeks...
    Also is it bad to eat mostly chocolate and pies on this day?? lol :)

  2. anbeav

    No you don't need a carb reset and a CKD approach is not pies and chocolate. It's not recommended because most do not need it and they turn it into a cheat day not a refeed and it results in spinning your wheels

  3. LIFEISWAITING

    OK Thanks.

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