What Is Ketosis?
"Ketosis" is a word you'll probably see when you're looking for information on diabetes or weight loss. Is it a good thing or a bad thing? That depends. Ketosis is a normal metabolic process, something your body does to keep working. When it doesn't have enough carbohydrates from food for your cells to burn for energy, it burns fat instead. As part of this process, it makes ketones. If you're healthy and eating a balanced diet, your body controls how much fat it burns, and you don't normally make or use ketones. But when you cut way back on your calories or carbs, your body will switch to ketosis for energy. It can also happen after exercising for a long time and during pregnancy. For people with uncontrolled diabetes, ketosis is a sign of not using enough insulin. Ketosis can become dangerous when ketones build up. High levels lead to dehydration and change the chemical balance of your blood. Ketosis is a popular weight loss strategy. Low-carb eating plans include the first part of the Atkins diet and the Paleo diet, which stress proteins for fueling your body. In addition to helping you burn fat, ketosis can make you feel less hungry. It also helps you maintain muscle. For healthy people who don't have diabetes and aren't pregnant, ketosis usually kicks in after 3 or 4 days of eating less than 50 grams of carbohydrates per day. That's about 3 slices of bread, a cup of low-fat fruit yogurt, or two small bananas. You can start ketosis by fasting, too. Doctors may put children who have epilepsy on a ketogenic diet, a special high-fat, very low-carb and protein plan, because it might help prevent seizures. Adults with epilepsy sometimes eat modified Atkins diets. Some research suggests that ketogenic diets might help lower your risk of heart disease. Other studies show sp Continue reading >>
What Would Happen If I Had A High-protein, Low-carb, Low-fat Diet For A Month?
Hi Douglas - Thanks for reaching out! I believe I answered a similar question of your's earlier today. The type of diet you're suggesting would definitely put you in a state of ketosis, which is very effective for fat-burning. There's a lot of back-and-forth in the health and fitness community about whether or not ketosis is a healthy long-term dietary solution, with issues like kidney disease being brought to light if you're in a constant state of ketosis. Personally, I'd suggest a high fat, moderate protein and low carb diet. Carbs are a NON-ESSENTIAL macronutrient, meaning that our bodies produce more than enough 'fast energy' on their own to support optimal functioning. On the flip side, fat and protein are ESSENTIAL macronutrients, and are foods that we MUST eat frequently in order to insure optimal functioning, as our bodies do NOT produce enough of these macros on their own. Fat is important to ingest for the sake of cognition, of joint lubrication and of inflammation reduction. Protein helps to build and repair lean muscle tissue. Hope this helps! If you have any further questions, feel free to email me at the address below. Continue reading >>
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How Are Reactive Oxygen Species Produced Physiologically In Cells?
In addition to User's answer... (cellular respiration in the mitochondria) Reactive oxygen species can be produced by oxidase enzymes such as NADPH oxidase, xanthine oxidase, monoamine oxidase, and the cytochrome p450 oxidase enzymes - many of which produce hydrogen peroxide as a byproduct. The hydrogen peroxide then can be converted into damaging hydroxyl free radicals by metal ions in the Fenton Reaction. See Oxidase The process of glycolysis also produces highly reactive intermediates like methylglyoxal. Methylglyoxal can also be produced via ketosis (see How is methylglyoxal produced in ketosis?) Finally, we have to define what "reactive oxygen species" is. Are aldehydes and alpha,beta unsaturated carbonyls examples of reactive oxygen species, for example? Are glucose and fructose also examples of ROS? They certainly could fit one definition of them - chemically reactive molecules containing oxygen. Continue reading >>
There is a lot of confusion about the term ketosis among medical professionals as well as laypeople. It is important to understand when and why nutritional ketosis occurs, and why it should not be confused with the metabolic disorder we call ketoacidosis. Ketosis is a metabolic state where the liver produces small organic molecules called ketone bodies. Most cells in the body can use ketone bodies as a source of energy. When there is a limited supply of external energy sources, such as during prolonged fasting or carbohydrate restriction, ketone bodies can provide energy for most organs. In this situation, ketosis can be regarded as a reasonable, adaptive physiologic response that is essential for life, enabling us to survive periods of famine. Nutritional ketosis should not be confused with ketoacidosis, a metabolic condition where the blood becomes acidic as a result of the accumulation of ketone bodies. Ketoacidosis can have serious consequences and may need urgent medical treatment. The most common forms are diabetic ketoacidosis and alcoholic ketoacidosis. What Is Ketosis? The human body can be regarded as a biologic machine. Machines need energy to operate. Some use gasoline, others use electricity, and some use other power resources. Glucose is the primary fuel for most cells and organs in the body. To obtain energy, cells must take up glucose from the blood. Once glucose enters the cells, a series of metabolic reactions break it down into carbon dioxide and water, releasing energy in the process. The body has an ability to store excess glucose in the form of glycogen. In this way, energy can be stored for later use. Glycogen consists of long chains of glucose molecules and is primarily found in the liver and skeletal muscle. Liver glycogen stores are used to mai Continue reading >>
Is It Safe For A Teenager To Follow A Ketogenic Diet?
As long as the teenager is getting high-quality protein, fats, and carbohydrates, yes, it is safe for a teenager to follow a ketogenic diet. High-quality is the key. For protein, choose meats that are as unprocessed as possible. Avoid things like lunchmeat, which is about as highly processed as you can get. Eggs, chicken, beef, fish, etc. For ketogenic, you don’t have to worry about “low-fat” because fat is crucial to a ketogenic diet plan. For fats, again, high quality, and as natural as possible. Avocado, olives and olive oil, nuts, nut butters and nut oils, coconut oil, palm oil, butter, duck fat, chicken fat, lard … just avoid hydrogenated oils and (of course) trans-fats. Some plans advise against corn and canola oils. For carbohydrates, high-quality means vegetable-sourced carbs, preferably those that are low in starch (or low glycemic impact), and minimal fruits, again, focusing on the lower-sugar fruits. So greens, spinach, lettuce, summer squashes, cruciferous veggies (cabbage, bok choy, etc), asparagus, and pod beans are good. Nightshades (eggplant, tomato, peppers, etc.) are fine if you can tolerate them. (Some people have sensitivities to them.) Potatoes, yams, peas, beans, and corn are limited because they are high in starches. Fruits like berries, citrus, and drupes are fairly safe in limited quantities (1 to 2 servings/day), but bananas and apples should be eaten much less frequently. Grains are strictly limited, if eaten at all, because they have a significant impact on blood sugar. A typical keto-friendly meal comprises a 3- to 6-ounce serving of meat, a couple of tablespoons of fat, and 2 to 3 servings of vegetables. So, for example, filet mignon topped with butter or bleu cheese, grilled asparagus drizzled with hollandaise, and creamed spinach Continue reading >>
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia. Related to ketosis: ketoacidosis ke·to·sis (kē-tō'sis), A condition characterized by the enhanced production of ketone bodies, as in diabetes mellitus or starvation. ketosis /ke·to·sis/ (ke-to´sis) accumulation of excessive amounts of ketone bodies in body tissues and fluids, occurring when fatty acids are incompletely metabolized.ketot´ic ketosis the abnormal accumulation of ketones in the body as a result of excessive breakdown of fats caused by a deficiency or inadequate use of carbohydrates. Fatty acids are metabolized instead, and the end products, ketones, begin to accumulate. This condition is seen in starvation, occasionally in pregnancy if the intake of protein and carbohydrates is inadequate, and most frequently in diabetes mellitus. It is characterized by ketonuria, loss of potassium in the urine, and a fruity odor of acetone on the breath. Untreated, ketosis may progress to ketoacidosis, coma, and death. See also diabetes mellitus, ketoacidosis, starvation. ketotic, adj. Acetonaemia The presence of an excess of acetone in the blood, which occurs in ketoacidosis due to alcohol abuse, uncontrolled diabetes (ketoacidosis), starvation and prolonged fasting. ketosis An abnormal ↑ in serum concentration of ketone bodies that does not produce acidosis. Cf Ketoacidosis. ke·to·sis (kē-tō'sis) Enhanced production of ketone bodies, as in diabetes mellitus or starvation. [ketone + -osis, condition] ketosis The presence of abnormally high levels of KETONES in the blood. These are produced when fats are used as fuel in the absence of carbohydrate or available protein as in DIABETES or starvation. Ketosis is dangerous because high levels make the blood abnormally acid and there is loss of water, s Continue reading >>
Tweet Ketosis is a state the body may find itself in either as a result of raised blood glucose levels or as a part of low carb dieting. Low levels of ketosis is perfectly normal. However, high levels of ketosis in the short term can be serious and the long term effects of regular moderate ketosis are only partially known at the moment. What is ketosis? Ketosis is a state the body goes into if it needs to break down body fat for energy. The state is marked by raised levels of ketones in the blood which can be used by the body as fuel. Ketones which are not used for fuel are excreted out of the body via the kidneys and the urine. Is ketosis the same as ketoacidosis? There is often confusion as to the difference between ketosis and ketoacidosis. Ketosis is the state whereby the body is producing ketones. In ketosis, the level of ketones in the blood can be anything between normal to very high. Diabetic ketoacidosis, also known as DKA, only describes the state in which the level of ketones is either high or very high. In ketoacidosis, the amount of ketones in the blood is sufficient to turn the blood acidic, which is a dangerous medical state. When does ketosis occur? Ketosis will take place when the body needs energy and there is not sufficient glucose available for the body. This can typically happen when the body is lacking insulin and blood glucose levels become high. Other causes can be the result of being on a low carb diet. A low level of carbohydrate will lead to low levels of insulin, and therefore the body will produce ketones which do not rely on insulin to get into and fuel the body’s cells. A further cause of ketosis, less relevant to people with diabetes, is a result of excessive alcohol consumption. Is ketosis dangerous? The NHS describes ketosis as a pote Continue reading >>
Will My Body Burn Fat If I'm Eating 20g Of Carbs A Day, Or Do I Need To Be In Ketosis?
Your body can and will burn fat regardless of whether you're in a state of nutritional ketosis, as long as you are consistently burning more calories than you are taking in. But if fat loss is your goal, a keto diet will likely get you where you want to go more quickly than any other diet/nutrition plan. Most people will enter the state of nutritional ketosis if they are consistently consuming 20g of net carbs per day. But you don't want to guess at what that that carb number is for you. And you don't have to. The carb limit for getting into a state of nutritional ketosis and staying there depends on your total daily calories, which is based on your age, weight, activity level, sex and weight loss goal, which you can quickly calculate here. From there it’s all about calculating the actual number of grams you need to take in for fat, protein, and carbs following the 75/20/5 keto ratio. And to come up with those number you simply multiply your total daily calorie goal by the percentage for each macro. You then divide each of those numbers by the calories per gram below: Fat = 9 calories per gram Protein = 4 calories per gram Carbs = 4 calories per gram Here's an example of how those macros would break down for the average male and female: Keep in mind that the carb number means net carbs. So when you're reading food labels be sure to subtract the grams of fiber from the grams of total carbs for your net carb number. For more information on following a keto diet, including free 4-week meal plans, visit Keto Diet Plan Explained, Best Ketogenic Diet Foods & Ketosis Diet Menu Continue reading >>
10 Signs And Symptoms That You're In Ketosis
The ketogenic diet is a popular, effective way to lose weight and improve health. When followed correctly, this low-carb, high-fat diet will raise blood ketone levels. These provide a new fuel source for your cells, and cause most of the unique health benefits of this diet (1, 2, 3). On a ketogenic diet, your body undergoes many biological adaptions, including a reduction in insulin and increased fat breakdown. When this happens, your liver starts producing large amounts of ketones to supply energy for your brain. However, it can often be hard to know whether you're "in ketosis" or not. Here are 10 common signs and symptoms of ketosis, both positive and negative. People often report bad breath once they reach full ketosis. It's actually a common side effect. Many people on ketogenic diets and similar diets, such as the Atkins diet, report that their breath takes on a fruity smell. This is caused by elevated ketone levels. The specific culprit is acetone, a ketone that exits the body in your urine and breath (4). While this breath may be less than ideal for your social life, it can be a positive sign for your diet. Many ketogenic dieters brush their teeth several times per day, or use sugar-free gum to solve the issue. If you're using gum or other alternatives like sugar-free drinks, check the label for carbs. These may raise your blood sugar levels and reduce ketone levels. The bad breath usually goes away after some time on the diet. It is not a permanent thing. The ketone acetone is partly expelled via your breath, which can cause bad or fruity-smelling breath on a ketogenic diet. Ketogenic diets, along with normal low-carb diets, are highly effective for losing weight (5, 6). As dozens of weight loss studies have shown, you will likely experience both short- and long Continue reading >>
A Comprehensive Beginner's Guide
What is a Keto Diet? A keto diet is well known for being a low carb diet, where the body produces ketones in the liver to be used as energy. It’s referred to as many different names – ketogenic diet, low carb diet, low carb high fat (LCHF), etc. When you eat something high in carbs, your body will produce glucose and insulin. Glucose is the easiest molecule for your body to convert and use as energy so that it will be chosen over any other energy source. Insulin is produced to process the glucose in your bloodstream by taking it around the body. Since the glucose is being used as a primary energy, your fats are not needed and are therefore stored. Typically on a normal, higher carbohydrate diet, the body will use glucose as the main form of energy. By lowering the intake of carbs, the body is induced into a state known as ketosis. Ketosis is a natural process the body initiates to help us survive when food intake is low. During this state, we produce ketones, which are produced from the breakdown of fats in the liver. The end goal of a properly maintained keto diet is to force your body into this metabolic state. We don’t do this through starvation of calories but starvation of carbohydrates. Our bodies are incredibly adaptive to what you put into it – when you overload it with fats and take away carbohydrates, it will begin to burn ketones as the primary energy source. Optimal ketone levels offer many health, weight loss, physical and mental performance benefits. Make keto simple and easy by checking out our 30 Day Meal Plan. Get meal plans, shopping lists, and much more with our Keto Academy Program. Looking for Something Specific? There are numerous benefits that come with being on keto: from weight loss and increased energy levels to therapeutic medical appl Continue reading >>
What's A Keto Diet?
What is a ketogenic diet and how does it work? The process was initially developed in 1924 by Dr. Russell Wilder as an effective, non-pharmacological treatment for intractable childhood epilepsy. The process works when the body is put into a metabolic state called Ketosis, where ketones become the main source of energy for the brain and body to function. The ketogenic diet plan is high in fat and low in carbohydrates while supplying adequate protein to the body. This specific combination changes the manner in which your body uses energy. Additionally, while reducing epileptic seizures, this process lowers glucose levels while improving the body’s resistance to insulin. So I know a lot of you are probably wondering "what is Ketosis?" am I right? By definition, it is when your body goes through a metabolic state in which the body transforms ketones created from fat into energy, instead of energy created from converting carbohydrates. What are they exactly did you ask? Biochemically speaking, ketones are organic, carbon-based compounds that contain a central carbon atom double-bonded to an oxygen atom and two carbon-containing substituents, denoted by “R.” Ketones are considered simple compounds because they do not contain chemical groups that are readily reactive. Fatty acids in the body are oxidized by the liver for energy production. There are 3 different ketone bodies produced in mitochondria of the liver: acetone, acetoacetic acid and beta-hydroxybutyric acid. Some of these fatty acids are oxidized by the liver for energy production while others can be partially oxidized to form the substrate acetoacetate, which is then converted to beta-hydroxybutyric acid; collective. These bodies produced in the liver are referred to as endogenous ketone bodies and are those Continue reading >>
What Is Ketosis?
First, a simple explanation of the process: the carbohydrates you eat are converted to glucose, which is the body’s primary source of energy. Whenever your intake of carbohydrates is limited to a certain range, for a long enough period of time, you reach a point where your body draws on its alternate energy system, fat stores, for fuel. This means the body burns fat and turns it into a source of fuel called ketones. (Ketones are produced whenever body fat is burned.) When you burn a larger amount of fat than is immediately needed for energy, the excess ketones are discarded in the urine. Being in ketosis means your body has burned a large amount of fat in response to the fact that it didn’t have sufficient glucose available for energy needs. Dietary ketosis is among the most misunderstood concepts in nutrition because it is often confused with ketoacidosis, which is a life-threatening condition most often associated with uncontrolled insulin-deficient Type 1 diabetes. In the Type 1 diabetic, the absence of insulin leads to a toxic build-up of blood glucose and an extreme break-down of fat and muscle tissue. This condition doesn’t occur in individuals who have even a small amount of insulin, whether from natural production or artificially administered. Dietary ketosis, however, is a natural adjustment to the body’s reduced intake of carbohydrates as the body shifts its primary source of energy from carbohydrates to stored fat. The presence of insulin keeps ketone production in check so that a mild, beneficial ketosis is achieved. Blood glucose levels are stabilized within a normal range and there is no break-down of healthy muscle tissue. The most sensitive tests of ketosis (“NMR” and “blood ketone level”) show that everyone is in some degree of ketosis e Continue reading >>
Ketosis: What Is Ketosis?
Ketosis is a normal metabolic process. When the body does not have enough glucose for energy, it burns stored fats instead; this results in a build-up of acids called ketones within the body. Some people encourage ketosis by following a diet called the ketogenic or low-carb diet. The aim of the diet is to try and burn unwanted fat by forcing the body to rely on fat for energy, rather than carbohydrates. Ketosis is also commonly observed in patients with diabetes, as the process can occur if the body does not have enough insulin or is not using insulin correctly. Problems associated with extreme levels of ketosis are more likely to develop in patients with type 1 diabetes compared with type 2 diabetes patients. Ketosis occurs when the body does not have sufficient access to its primary fuel source, glucose. Ketosis describes a condition where fat stores are broken down to produce energy, which also produces ketones, a type of acid. As ketone levels rise, the acidity of the blood also increases, leading to ketoacidosis, a serious condition that can prove fatal. People with type 1 diabetes are more likely to develop ketoacidosis, for which emergency medical treatment is required to avoid or treat diabetic coma. Some people follow a ketogenic (low-carb) diet to try to lose weight by forcing the body to burn fat stores. What is ketosis? In normal circumstances, the body's cells use glucose as their primary form of energy. Glucose is typically derived from dietary carbohydrates, including: sugar - such as fruits and milk or yogurt starchy foods - such as bread and pasta The body breaks these down into simple sugars. Glucose can either be used to fuel the body or be stored in the liver and muscles as glycogen. If there is not enough glucose available to meet energy demands, th Continue reading >>
Is The Keto Diet Effective?
Turns out Keto/ketosis can be very effective in a variety of applications. There is pretty awesome keto research happening right now, too. Seizures: Several thousand years ago, doctors weren't sure why fasting was such an effective treatment for children with seizures. Turns out, restricting carbohydrates and surviving on ketones is something the brain really likes. Obviously, fasting isn't an effective long-term solution, but nutritional ketosis (restricting net carbs to 20g-40g per day) is a great alternative, can be maintained indefinitely, and has helped children (and adults) control their seizures in cases where medicine couldn't. (90% achieved better management of their seizures, and about half of those were able to eliminate seizures entirely). Oxygen Toxicity: I was listening to a Tim Ferriss podcast with Dom D'Agostino (Dom D’Agostino on Fasting, Ketosis, and the End of Cancer ) and D'Agostino mentioned an experiment he conducted to test the limits of a body in ketosis when exposed to oxygen toxicity. Essentially, imagine a Navy SEAL team that has to remain underwater in a pond to evade detection. Their scuba gear cannot release bubbles, so they use a "rebreather" to recirculate the exhaled gas, but one of the risks in that situation is oxygen toxicity (see: Rebreather diving). The experiment involved inducing ketosis in rats, placed them in a pressurized environment to simulate the pressure of being underwater, and exposed them to 100% oxygen. Normally the rats would experience seizures after 15 minutes, however the keto-adapted rats were seizure-free for more than an hour! I suspect the mechanism that creates seizures in this situation is different from the mechanism that creates seizures in children, however the "treatment" of ketosis is identical and pret Continue reading >>
Ketosis Explained – For Weight Loss, Health Or Performance
Get Started Ketosis is a natural state for the body, when it is almost completely fueled by fat. This is normal during fasting, or when on a strict low-carb diet. Ketosis has many potential benefits, but there are also side effects. In type 1 diabetes and certain other rare situations excessive ketosis can even become dangerous. On this page you can learn all about how to harness the benefits of ketosis, while avoiding any problems. It all starts with understanding what ketosis is. Choose a section, or keep reading below for all of them. Ketosis ExplainedKetosis Explained BenefitsBenefits How to Get Into KetosisHow to Get Into Ketosis Ketosis ExplainedSymptoms & How to Know You’re In Ketosis Side Effects, Fears & Potential DangersSide Effects, Fears & Potential Dangers How to Reach Optimal KetosisHow to Reach Optimal Ketosis ketones Ketosis Explained The “keto” in the word ketosis comes from the fact that it makes the body produce small fuel molecules called “ketones”.1 This is an alternative fuel for the body, used when blood sugar (glucose) is in short supply. Ketones are produced if you eat very few carbs (that are broken down into blood sugar) and only moderate amounts of protein (excess protein can be converted to blood sugar). Ketones are produced in the liver, from fat. They are then consumed as fuel in the body, including by the brain. This is important as the brain is a hungry organ that consumes lots of energy every day,2 and it can’t run on fat directly. It can only run on glucose… or ketones. Maximizing fat burning On a ketogenic diet your entire body switches its fuel supply to run almost entirely on fat. Insulin levels become very low and fat burning increases dramatically. It becomes easy to access your fat stores to burn them off. This is o Continue reading >>
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