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Ketosis When To Measure

Breath Acetone As A Measure Of Systemic Ketosis Assessed In A Rat Model Of The Ketogenic Diet

Breath Acetone As A Measure Of Systemic Ketosis Assessed In A Rat Model Of The Ketogenic Diet

Background: The mechanism of a high-fat, low-carbohydrate ketogenic diet (KD) in alleviating drug-resistant epilepsy is unknown but may be related to systemic ketosis induced under this treatment. The need for frequent measurement of systemic ketosis, which is essential for improving maintenance of the KD in patients and for studying mechanism of the KD action, has prompted us to validate the breath acetone test as a fast, reliable, and noninvasive tool for ketosis assessment. Methods: A rat model of the KD that allowed frequent blood sampling was used to investigate how well breath acetone reflects plasma β-hydroxybutyrate (β-HBA), the most commonly measured ketone body. Rat pups (20 days of age) were introduced to and maintained on a KD or control diet for 33 days. During this period, breath acetone, plasma β-HBA, blood glucose, and body weight were measured approximately every 4th day. A correlational analysis of breath acetone and plasma β-HBA was conducted. Results: Breath acetone was found to be a significant predictor of plasma β-HBA over a clinically relevant range of β-HBA concentrations (r2 = 0.75; P <0.001). We have proposed a general formula that allows the value of plasma β-HBA to be estimated based on breath acetone measurement. Conclusions: Breath acetone is an accurate measure of mild to moderate systemic ketosis. The noninvasive nature of this test will be useful for day-to-day implementation of the KD, searching for better forms of this diet, and understanding the role of ketosis in the mechanism of the KD action. A high-fat, low-carbohydrate ketogenic diet (KD) is an effective treatment for drug-resistant epilepsy in children (1)(2)(3) and, possibly, in adults (4). It is likely that the KD works by a unique mechanism because it is active when o Continue reading >>

A Detailed Guide On How To Test Your Ketone Levels

A Detailed Guide On How To Test Your Ketone Levels

I have to be honest with you. I’ve been making some critical mistakes. I was assuming that I was in ketosis for months but I’m now finding out that isn’t the case. Not even close. I’ve finally hunkered down and have been measuring my ketones the right way and the results have been pretty surprising. I was eating too much protein, and too little fat. I was eating too frequently. I was eating too few calories. I never would have known this without testing. Time for you to learn from the mistakes I made and test the right way. Ketosis can be a powerful nutrition approach to use switch your metabolism to prioritize for fat loss, mental output, physical performance, and much more. The main problem? Many people just assume that if they are “low carb” they are in ketosis, but think again. How do you know if you’re actually in ketosis? As I love to say, “test, don’t guess” when it comes to your health. (Still trying to get “track, don’t slack” to catch on…) I’ll outline in this article the three ways to test your ketone levels and which you should be doing when. HOW TO TEST YOUR KETONE LEVELS: THREE DIFFERENT WAYS There are three testing methods because there are three forms of ketones in your body: acetate, acetoacetate, and beta-hydroxybutryate. Each of these ketone bodies do slightly different things and are in different forms, so they can be tested individually with different methods. The three different area these ketones exist in your body are your breath, urine or blood. The good news is that all of these ketone level measurements can be done at home, by yourself. You don’t need to go to a lab or use any fancy high-tech gadgetry. Tracking consistently, at least when you’re getting used to a ketogenic diet, is important so you know how mu Continue reading >>

Ep104: How Do You Measure For Ketosis?

Ep104: How Do You Measure For Ketosis?

The differences in blood testing strips and acetone levels in your breath. Drew welcomes Dr. Joe Anderson to the podcast to have an in-depth conversation about testing, measuring and tracking ketones. Dr. Anderson leads the Clinical Science division at LEVL and is the owner of Anderson Bioscience, a biotechnology consulting firm in Seattle. His expertise in pulmonary physiology and breath research make him uniquely qualified to create the levels of acetone in breath. During the conversation, Drew and Dr. Anderson discuss the different options for measuring and tracking acetone and beta-hydroxybutyrate levels, when it’s best to test and the future of ketosis as therapy for medical ailments. If you like this podcast subscribe & review it on iTunes | Stitcher. Key Takeaways: [04:21] How Dr. Anderson ended up in the business of ketosis. [09:19] The 3 different types of ketones in the human body. [13:48] The LEVL product is registered with the Food and Drug Administration to measure acetone. [17:49] How the LEVL device works, what it measures and what it can tell you. [27:55] When is the best time to test breath acetone levels to get the best data? [38:26] The future of ketosis is more than weight loss. Sponsors: Organifi – Use the code ‘Fit2fat2fit’ for 20% your entire order Mentioned in This Episode: Transform with Drew’s Fit2Fat2Fit 6-month Program Drew on Social Media: @fit2fat2fit Email Drew: [email protected] Continue reading >>

3 Best Ways To Measure Ketones For Your Ketogenic Diet (review & Buyers Guide)

3 Best Ways To Measure Ketones For Your Ketogenic Diet (review & Buyers Guide)

How do you get accurate readings of ketones? Which methods actually work? These are common questions I going to help you with in this article. Anyone interested in using the latest nutritional research to improve their health has likely heard of a ketogenic diet. Ketogenic diets are a simple way to get your metabolism to prioritize the consumption of fatty acids, also known as ketones, when at rest or exercising. While there is a wide body of research that confirms the benefits of this type of nutritional plan, for the average user at home – one big question remains. How can you measure ketone levels to ensure your body is reaching a perfect state of ketosis? Without an accurate method of ketosis measurement, you will never achieve an optimized LCHF or ketogenic diet. However, it has not always been easy to measure your level of ketosis at home. At least this concern is now a thing of the past, because there are many ways to measure ketone levels easily and accurately in the comfort of your own home. Find out the very best method to test your level of nutritional ketosis that strikes the perfect balance of ease, price and quality. Before getting too deep into the different methods for measuring ketosis, it is important to first look at exactly why measuring them is so important and to clarify some of the more complex scientific terms. Ketone Testing Terminology If you have decided to try a ketogenic diet to achieve nutritional ketosis, then finding an accurate way to measure your ketone levels is important. You need to be able to maintain yourself in the optimal zone where fat is used as energy rather than glucose. Too little ketone and you will not see any positive effects. But higher levels give no real benefit and could indicate a serious problem with your diet. Li Continue reading >>

Lose Weight By Achieving Optimal Ketosis

Lose Weight By Achieving Optimal Ketosis

Do you want to lose weight? Here’s number 16 of my 18 best tips. All of the published tips can be found on the How to Lose Weight page. Before we get started, here’s a short recap of the tips so far: The first and most crucial piece of advice was to choose a low-carb diet. The next were eating when hungry, eating real food, eating only when hungry, measuring progress wisely, being persistent, avoiding fruit, beer and artificial sweeteners, review your medications, stressing less and sleeping more, eating less dairy and nut products, stocking up on vitamins and minerals, using intermittent fasting and finally, exercising smart. This is number sixteen: 16. Get into optimal ketosis Warning: Not recommended for type 1 diabetics, see below. We’ve now arrived at tip number 16. If you’re still having trouble losing weight, despite following the 15 pieces of advice listed above, it might be a good idea to bring out the heavy artillery: optimal ketosis. Many people stalling at weight plateaus while on a low carb diet have found optimal ketosis helpful. It’s what can melt the fat off once again. So how does this work? A quick run-through: The first tip was to eat low carb. This is because a low-carb diet lowers your levels of the fat-storing hormone insulin, allowing your fat deposits to shrink and release their stored energy. This tends to cause you to want to consume less calories than you expend – without hunger – and lose weight. Several of the tips mentioned above are about fine-tuning your diet to better this effect. Video course Do you know exactly how to eat a low-carb and high fat diet (LCHF)? This is required for ketosis. If not the easiest way is watching this high quality 11-minute video course on how to eat LCHF, and the most important things to think a Continue reading >>

How To Know If You’re In Ketosis: A Guide To Testing Ketone Levels

How To Know If You’re In Ketosis: A Guide To Testing Ketone Levels

Ketosis can be a powerful way to use your metabolism for fat loss, mental output, physical performance as well as many other health benefits. But how do you know if you’re actually in ketosis? As the old adage goes “test, don’t guess” when it comes to your health. In this guide, we’ll show exactly how to test your ketone levels to know if you’re in ketosis so you can make sure you’re getting all of the benefits that ketosis has to offer. There are three primary forms of ketones in your body, acetone, acetoacetate, and beta-hydroxybutryate. Each of these compounds do different things in the metabolism of ketosis and can be tested individually with differing techniques. Not all measurement is created equally, however, and some can be better than others for different purposes or times. The three different ketone bodies can be measured when they spill over into three different areas of your body: your breath, urine or blood. The good news is that all of these ketone level measurements can be done at home, by yourself. You don’t have to go to any lab or use any fancy high tech equipment. Tracking diligently, at least when you’re getting used to ketosis based diets, is important so you know how much you react to different variables like exercise, type and amount of food, and amounts of exogenous ketone supplements. Also, the optimal level of ketones for specific goals can vary per person. Knowing the amount where you thrive in the goal you want to achieve (and consistently checking if you’re hitting that amount) is the fastest way to reach your goals. Testing levels of ketones with urine strips (acetoacetate) One of the ketone bodies, acetoacetate, can be measured directly in the urine if they are in excessive levels. The way metabolic substrates get into Continue reading >>

Ketogenesis, Measuring Ketones, And Burning Fat Vs Being In Ketosis

Ketogenesis, Measuring Ketones, And Burning Fat Vs Being In Ketosis

I cannot tell you how many emails I get from people fretting over their ketone levels. It’s time to set the record straight on this issue. I wish there was someplace I could refer people for reliable information on this subject, but I haven’t come across a blog post or podcast interview that explains things satisfactorily. At least, not to my satisfaction. And that is and always has been my goal in writing my blog: I explain things the way I would want someone to explain them to me, if I were new to all this. And since no one—as far as I know, anyway—has tackled this subject the way I would, I finally had to just sit down and write this. If you feel it’s educational, please share it in the low carb and/or ketogenic circles you frequent, because I know this issue comes up all the time in ketogenic forums and Facebook groups. (And if you know of other good resources on this topic, feel free to provide a link in the comments, and I’ll update this post to include it.) There are few issues more controversial regarding ketogenic diets than whether you should measure your ketones. There are valid reasons to measure, but there are also a lot—a lot—of misconceptions about measuring ketones and how to interpret the data. So let’s get into when and why it’s a good idea to measure, who doesn’t need to measure, and most important, what the numbers mean. (I said who “doesn’t need to” measure rather than who shouldn’t measure because if you want to measure, then go ahead. There’s really no should or shouldn’t here. But if you choose to measure, you need to understand how to interpret and understand the numbers so you don’t jump to illogical and false conclusions.) I will also be covering the difference between being fat adapted versus in ketosis. I Continue reading >>

What Are The Optimal Ketone Levels For A Ketogenic Diet?

What Are The Optimal Ketone Levels For A Ketogenic Diet?

If you’ve just started a ketogenic diet, then you’ll know that it can be really tough to figure out if you’re doing keto right. Am I eating too many carbs? Too much protein? Should I still be feeling tired? When is the fat burning supposed to start? It’s confusing, and one of the most confusing aspects is what your optimal ketone levels are supposed to be. Unlike most other diets, the ketogenic diet is designed to put your body into a state of ketosis in order to get your body to start burning ketones instead of the glucose that it usually burns when you eat a high carb standard American diet (SAD). But to know whether you’re in ketosis and whether your body has enough ketones circulating for you to use as energy instead of glucose, you have to measure your actual ketone levels and then determine whether they’re high enough for you to be reaping the benefits of the ketogenic diet. If you’ve tried searching for this information already, then you’ll know that there’s some controversy depending on which expert you follow. So in this article, we’ll tell you exactly what the different experts are suggesting are the optimal ketone levels as well as give you recommendations for what ketone levels you should be aiming for depending on your goals with a ketogenic diet. A Few Quick Notes Before We Start… If you’re looking for signs other than testing your actual body ketone levels as to whether you’re in ketosis or not, then please check out this article instead that provides you with signs you’re in ketosis. If you’re a type 1 diabetic, then this article is not for you and the optimal ketone levels suggested below are not applicable to you. Please check out the tons of other ketone level articles on the web to ensure your ketone levels do not reach Continue reading >>

When And How Should You Measure Ketosis?

When And How Should You Measure Ketosis?

If you are following a low carbohydrate diet that is based on the ketogenic principles then measuring if you are in ketosis may be an important goal for you. There are times when measuring the specific ketone level may not be required. When is measuring ketosis really needed? My advice to people is if you are following a ketogenic diet for a therapeutic reason (such as epilepsy, cancer, MS, diabetes etc.) then measuring the ketogenic level will be important for you. This is because from the evidence that we have to date, we can see some correlation that in order for the ketogenic diet to be effective, the ketone bodies need to be consistently elevated. If you are someone that is following a ketogenic diet for weight loss, then measuring ketosis through objective ways (I will go over them below), really may not be necessary. There is still this notion that I see online form various Keto Coaches that having a high ketone level in the blood or breath will automatically mean you will lose more weight. I want to say categorically that this is NOT the case. “High blood ketone levels do not automatically mean you will experience a fat loss”. In the next few weeks I will detail in a weekly email exactly why this is the case but for now back to the topic of how to measure ketosis. How to measure ketosis? Subjective Measurements: There are several ways in which you can detect if you are in a ketogenic range. The first way is looking at more subjective measurements. What I mean by this is measurements that focuses more on how you are feeling. In the beginning, you can experience certain symptoms including: nausea, headaches, fatigue, bad breath and weak legs. These symptoms are a sign that your body is now switching from using glucose to using fat for energy. Another subjectiv Continue reading >>

The Best Ketone Meters To Monitor Ketosis – Christmas 2017

The Best Ketone Meters To Monitor Ketosis – Christmas 2017

The goal of a high-fat, low-carb diet is to get into a state called Ketosis where the body burns fat as fuel rather than using glucose as its source of energy. Types of Ketone Meters There are several types of ketone meters available that monitor ketosis in vastly different ways, some more accurate than others and some more convenient others. We’ll discuss 3 types of Ketone Meters available starting with the best on the market today in 2017. Ketonix Breath Ketone Analyzer The Ketonix breath analyser doesn’t use any blood glucose test or test strip, it works by analysing acetone on your breath that your body produces when you’re in a state of ketosis. The Ketonix is slightly less accurate as blood ketone and glucose meters are per test. But they are more convenient With the Ketonix, you can test yourself an unlimited amount of times, hourly if you like. Which is ideal if you want to see how various foods effect ketosis after you’ve eaten them or even the effects exercise has. The Ketonix is affordable when you take into account the price of test strips for blood monitors. (Many companies give away cheap versions of blood monitors but make their money on testing strips). The Ketonix has no test strips and requires no further outlay. Ketonix also comes with software that will keep a log and also calibrates the device to the optimal settings for your goals. If you’re trying to monitor ketones under conditions such as athletic performance, weight loss, diabetes, alzheimer’s or epilepsy. The Ketonix adjusts its settings to test whether you’re in the ideal range for that condition. The Ketonix Breath Ketone Analyzer is a one-off payment you can read more & check them out here. Blood Ketone Meter One of the best & most precise ways of monitoring ketosis is with a Continue reading >>

Why I Stopped Testing My Ketones On A Ketogenic Diet

Why I Stopped Testing My Ketones On A Ketogenic Diet

On measuring Ketones. Like many people, when I first started a Ketogenic diet in early 2014 I bought the Ketostix and just couldn’t wait to see the color change. And change it did! It was neat, and it provided motivation for me to continue. Eventually, I got a blood meter, a breath meter and spent lots of time (and money) testing ketones. Between a Ketonix Breath Ketone Analyzer, as well as dozens of blood ketone test strips, I’ve probably spent well over $500 testing ketones. The main thing I learned from my extensive ketone testing regimen is that the results vary widely and there’s little application to my goals. Eventually, I stopped testing and here are several reasons why: 1. Burning fatty acids from fat is the main benefit of a ketogenic diet On a ketogenic diet, some of the brain’s energetic demand is fueled by ketones, but the heart, muscles, etc. are fueled by fatty acids. Most of the energy we utilize both at rest and at sub-maximal exertion on a ketogenic diet is fatty acid, not ketones. Quoting Dr. Ron Rosedale on chasing ketones at the Keto Summit: “I don’t want people to have the mindset that it’s the ketones that are the benefit of the diet. They are a beneficial side effect, but the main benefit is that you are burning fatty acids from fat. The more fatty acids from fat you are burning, the less glucose you need to burn. And that’s really where you are getting the benefit…So ketones are great but the term ketogenic diet indicating that the diet is so good because you are generating all these ketones is a misinterpretation of the benefit. The main benefit is that you are burning fatty acids, and as a side effect of burning fatty acids you are producing ketones that your body can burn too!” 2. Urine Ketones aka “peetones” are ridic Continue reading >>

How To Detect Ketosis

How To Detect Ketosis

How can you tell if your low-carbing efforts have been effective enough to induce ketosis? Learn how to check your ketones! The state of ketosis The state of ketosis means that the body has switched from depending on carbohydrates for energy to burning fats for fuel. This means not only dietary fats (olive oil, guacamole, deep-fried pig ears), but also all the jiggly bits around your waist — clearly a desirable state for anyone looking to shed extra weight. When the body metabolizes fat, it generates molecules called ketones (also known as ketone bodies). As you restrict carbohydrate intake and amp up the dietary fat, more fat is metabolized and a greater quantity of ketones are created. Most of the cells in your body — including those in your brain — are able to use ketones for energy, although many people experience a few days’ adjustment period, often called the low carb flu. One of the varieties of ketones generated — acetone — cannot be used by the body and is excreted as waste, mostly in the urine and the breath. Conveniently, this makes it very simple to measure whether or not you are in ketosis. Upon entering ketosis, some people report a distinct change in the smell of their breath as a result of the extra released acetone. It could be “fruity” — it’s been likened to overripe apples — or even “metallic.” If you notice this happening during your first few days of changing your diet, it could be a good sign you’re in ketosis. The unusual smell isn’t anything dangerous, but it could be annoying. Drinking plenty of water should help, or get yourself some sugar-free gum. Most people report “keto-breath” diminishing after the first few weeks. Detecting ketones in urine The more accurate way — and the one we recommend — to check f Continue reading >>

Measuring Ketosis

Measuring Ketosis

Now this topic is important to a certain extent in my opinion simply because I live this life so when I compare my thoughts and assumptions to what others say… I could only agree to some of it. All-in-all, measuring your ketones is important but since you have me… I would like to make things as simple as possible. There are three way to measure your ketone levels. acetoacetate (AcAc), The primary ketone in the urine Beta-hydroxybutyrate (BHB), The primary ketone in the blood Acetone, The primary ketone in the breath So which way to go? Ideally, Beta hydroxybutyrate is the best way to measure ketosis as you are measuring it within your blood and this tends to be for the long term of nutritional ketosis of a ketone measurement level of about 1 to 3 millimolar per liter. The reason I say “ideally” is because through my experience… I feel as though this is not something that is mandatory if you know what you are doing. For years, ketone levels have been measured through the urine and to me it gets the job done because I feel that all you need is that first indication of ketone production to get things rolling especially with the smackfat approach to weight loss. I am also not a fan of how expensive testing the blood can get when you have to constantly measure you ketone levels during your personal process of learning your tolerances to the foods you consume in achieving your custom fit for ketosis. As more research is done… testing your ketone levels through the breath is an adequate approach because it is said that measurements are close to the blood version of testing which seems promising but I must say that I feel these approaches to testing ketone level to just about reach nutritional ketosis is some what counter productive. I say this because this would pr Continue reading >>

Measuring Ketones: How To Know If You’re In Ketosis

Measuring Ketones: How To Know If You’re In Ketosis

Measuring ketones is often the difference between a keto diet that works, and getting frustrated and not getting the results of everyone else. Well, over the years I have been asked this question very often – receiving thousands of emails in fact about this question as it is one of the more popular ones. I’m going to address it here once and for all for you, to help you make an informed decision: AM I IN KETOSIS? I’ve been lucky enough to dissect this question and have found some answers. After reading through many people’s diets with a fine comb I am unfortunately going to say most people are not in ketosis for very simple reasons. It is very easy to overlook some critical problems. If you’re one of these people reading this and have tried keto once before without getting any results, this may be your answer. Were you really in ketosis? Measuring ketones would inform you with certainty – especially starting out. Some of the most common problems would be, just not looking at food labelling close enough. Getting caught out by just plain old smoked salmon; not seeing the dextrose in the curing process. Dextrose and maltodextrin are sugars, and even some sweeteners, have hidden sugars in them. Now is this much of a problem? Well yes and no! If you want to be burning in the upper level of nutritional ketosis this will be a problem. However too many of these mishaps would more than likely mean that you’re not burning ketones and would be doing more of a low carb high fat diet (LCHF), rather than ketosis. Personally I think the LCHF diet is probably more achievable and sustainable long term. I only say this as I have had enough emails suggesting keto is not the easiest diet to maintain. But don’t get me wrong – in my opinion, the keto diet is still the best Continue reading >>

How To Measure Ketones And Optimize Ketogenic Diets

How To Measure Ketones And Optimize Ketogenic Diets

The problem with diets is that we think that one diet should be good for everyone. But research and N=1 experiments show that’s not the case. Learn about measuring ketones and ketosis to understand how your low carb or high fat diet is really affecting you. If there is one area of our bodies that is debated to extremes, with literally hundreds of differing strong opinions on it, it’s nutrition. For many, beliefs about nutrition and diet are tribal. We put ourselves in different camps and we war agains the other camps. Whether it be paleo, low fat, low carb, Atkins, high fat, low protein, vegan, raw vegan and so on. It’s exactly this sort of area where I see data as essential. Without data we have no hope of cutting through the maze of opinions to get to what really works. Part of the problem with nutrition and diets is that we tend to think that one diet should be good for everyone. But increasingly, research and N=1 experiments, are showing that that isn’t the case. And this is exactly why you should pay attention to today’s show. Today, we’re looking at what has relatively recently become the fastest growing nutrition or diet trend. The high fat diet. Also known in different guises as the ketogenic diet, or the low carb diet. And specifically how this can affect our different individual biochemistries, how we can measure “Ketosis” and other biomarkers to understand how our specific biology is reacting to it… and allowing us to troubleshoot and course correct when it isn’t getting the desired results we’re looking for from it. Today’s guest is Jimmy Moore. In 2004, Jimmy, at 32 years, weighed 410 pounds. Since then he has transformed his own biology, shedding all that additional weight with low carb and ketogenic diets. He has also interviewed n Continue reading >>

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