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Ketosis When Dying

Adenohypophyseal Changes In Patients Dying Of Acute Renal Tubular Necrosis ‡

Adenohypophyseal Changes In Patients Dying Of Acute Renal Tubular Necrosis ‡

Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.5M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. Articles from The Yale Journal of Biology and Medicine are provided here courtesy of Yale Journal of Biology and Medicine Continue reading >>

Ketogenic Diet And Alcohol Effects On Ketosis Is It Keto Friendly?

Ketogenic Diet And Alcohol Effects On Ketosis Is It Keto Friendly?

Ok, first thing is first, before we get into the Ketogenic diet and alcohol’s effect on ketosis; that is most western cultures drink far too much. Now I know most people (those on a keto diet included) don’t want to hear that, and I’m not trying to be a party-pooper, but I’m here to tell you the truth as I know it, not to tell you what you want to hear. Anyway, there’s a little room for debate depending on how you read the evidence on whether there’s room in a Ketogenic Diet for alcohol and whether alcohol will throw you out of ketosis, it may or may not, but there are certainly side effects to be aware of, some very dangerous. Ketogenic Diet and Alcohol Effects on Ketosis I’ve read quite a few articles and forums about keto and alcohol and almost all of them dance around it looking for some loophole in the figures to squeeze in some amount of alcohol. Many try to satisfy the vast majority who think giving away alcohol on a keto diet will be a deal breaker. They all try hard I have to say. Let’s be real, if you’re dying to fit alcohol into your ketogenic diet and it’s a must have for you, I doubt the small amount that could possibly fit in will satisfy you. Here are a few things to consider if you’re to drink alcohol while trying to maintain a keto diet: You will undoubtedly get drunk much quicker on a ketogenic diet than if you weren’t. Hangovers will be worse, as you know a keto diet flushes your body of water retention and the chances that you’ll be staying hydrated while drinking is slim, alcohol is notorious for dehydrating you. Even if alcohol itself doesn’t kick you out of ketosis, when tipsy self-control goes out the window, you’re likely to eat whatever is in front of you. If you are determined to include alcohol in your ketogenic Continue reading >>

7 Signs You Might Be In Ketosis When Doing The Ketogenic Diet

7 Signs You Might Be In Ketosis When Doing The Ketogenic Diet

One of the main goals of starting the ketogenic diet is to get your body into a metabolic state known as ketosis. Note: If you don’t know what the ketogenic is all about then check out the Ketogenic Diet: Beginner’s Guide to Keto and Weight Loss. This is when your body starts to produce a lot of ketones to supply energy for your body. Why is this good? Because it means your body has converted from a sugar-burner to a fat-burner. If your body is burning fat for energy then something amazing starts to happen. The fat on your body starts to disappear. But how do you know when you’re in ketosis? Besides using test strips or an instrument there are some signs that your body will give. 7 Signs You Might Be in Ketosis These don’t 100% guarantee that your body is in ketosis but if it is in ketosis then these signs will appear. 1. Weight Loss One of the obvious signs of ketosis is weight loss but this can also be pretty deceptive because many people don’t experience the kind of weight loss that they expect. This can happen for a variety of reasons but when you get close to entering ketosis or do enter ketosis you’ll find that you lose a healthy amount of weight quickly. For example, when you switch to low carbs you usually experience significant weight loss in the first week. In fact, my wife lost 12 lbs in the first 28 days of Keto and I lost 13. This isn’t your body burning fat but finally being able to release the water that was being held by the fat cells. If your fat cells don’t release this water then they can’t flow through the bloodstream to be used as fuel so losing water weight is a good thing. After the initial rapid drop in water weight, you should continue to lose body fat consistently if you are able to stick with the low-carb aspects of the diet Continue reading >>

Keto To Stay Alive With Cancer

Keto To Stay Alive With Cancer

Yes, the title of this blog entry is provocative, it is provocative for a reason. I am tired of hearing about cancer patients dying because they were told there was nothing they could do, or they agreed to the standard treatment even if that treatment didn’t have good statistics associated with it. It is important to understand how cancer cells proliferate in order to understand why something so simple as staying on a ketogenic diet can keep cancer at bay. All cells require fuel to produce ATP for energy and proliferation. Under a normal western modern-day diet, that fuel is glucose. Under conditions of extremely low carbohydrate and moderate protein intake, that fuel is fat. All cells but cancer cells can utilize ketone bodies (specific fats) as their fuel source. Cancer cells require 19 times the amount of glucose as a normal cell for their ATP production. They can only use this one pathway to fuel production. When serum glucose levels drop below 80, cancer cells start having difficulty staying alive, let alone dividing. In instances of low fat and high carb dieting, when someone misses a meal, they often feel weak and dizzy. But when eating a high fat diet with very low carbs, that bad feeling is not there, even when missing a meal. It’s not there because their brain is happy with ample fuel for activity. That fuel is fat. Almost all of my cancer patients come to me thinking they haven’t been eating too many carbs, but almost all of them have signs of insulin resistance, including higher than normal fasting glucose levels and difficulty bringing their serum glucose levels below 80 on the “induction” phase of the keto diet. Until very recently, American institutions had not been looking at ketogenic dieting as a way to treat cancer or to boost treatments. Th Continue reading >>

Journey Into Ketosis Part Ii

Journey Into Ketosis Part Ii

TL;DR This is a journal of my first month of ketosis. A quick recap of Part I: Ketosis is when your body metabolizes fat instead of sugar as its primary fuel source. To enter ketosis you must eat fewer than 50 grams of carbs per day for a minimum of two weeks, and ideally 60-80% of your diet is fat. You can measure blood ketones with over-the counter-tests. Ketones are the preferred fuel for organs like your brain, heart, and muscles. Ketosis is safe and all humans show improved blood lipid profiles, profound anti-inflammation, and weight loss with lean muscle mass preservation in ketosis, better than any other diet. May 2014: The Descent Of Insulin I had just returned from a two week long trip to Israel and Jordan. On the flight back I finished reading The Art And Science Of Low Carbohydrate Living, which answered all my questions about ketosis. (The Art and Science...Performance is a wonderful, short follow up, and Keto Clarity is on the to-read list.) I had been "paleo" for about five years, which for me meant avoiding grains and most sugars. I was not striving for high fat, and I still occasionally craved sugar. One way to know you've achieved ketosis is measuring blood levels of beta-hydroxybutyrate, or BOHB. It's the fuel your liver produces when it metabolizes fat. Your organs, especially your brain, consume it copiously. You can measure BOHB by pricking your finger with a Precision Xtra lance, bleeding on to a ketone test strip, inserting the strip into the Precision Xtra, and waiting. It will spit out your blood ketone density in milligrams of ketones per millimoler of blood. The (semi-arbitrarily) decided on level for a human to be in "nutritional ketosis" is a minimum of 0.5 mg/mmL. I was eating "low carb" for five years, so I figured this was easy, and I was Continue reading >>

Ketosis Vs. Ketoacidosis: What You Should Know

Ketosis Vs. Ketoacidosis: What You Should Know

Despite the similarity in name, ketosis and ketoacidosis are two different things. Ketoacidosis refers to diabetic ketoacidosis (DKA) and is a complication of type 1 diabetes mellitus. It’s a life-threatening condition resulting from dangerously high levels of ketones and blood sugar. This combination makes your blood too acidic, which can change the normal functioning of internal organs like your liver and kidneys. It’s critical that you get prompt treatment. DKA can occur very quickly. It may develop in less than 24 hours. It mostly occurs in people with type 1 diabetes whose bodies do not produce any insulin. Several things can lead to DKA, including illness, improper diet, or not taking an adequate dose of insulin. DKA can also occur in individuals with type 2 diabetes who have little or no insulin production. Ketosis is the presence of ketones. It’s not harmful. You can be in ketosis if you’re on a low-carbohydrate diet or fasting, or if you’ve consumed too much alcohol. If you have ketosis, you have a higher than usual level of ketones in your blood or urine, but not high enough to cause acidosis. Ketones are a chemical your body produces when it burns stored fat. Some people choose a low-carb diet to help with weight loss. While there is some controversy over their safety, low-carb diets are generally fine. Talk to your doctor before beginning any extreme diet plan. DKA is the leading cause of death in people under 24 years old who have diabetes. The overall death rate for ketoacidosis is 2 to 5 percent. People under the age of 30 make up 36 percent of DKA cases. Twenty-seven percent of people with DKA are between the ages of 30 and 50, 23 percent are between the ages of 51 and 70, and 14 percent are over the age of 70. Ketosis may cause bad breath. Ket Continue reading >>

The Beginners Guide To Ketosis: Investigating Low-carb, High-fat Eating

The Beginners Guide To Ketosis: Investigating Low-carb, High-fat Eating

The only hard and fast rule of health is that health is personal and what works well for one person may not work for someone else. Aside from that rule, there are “frameworks” that seem to benefit large groups of people. One more level down from that are alternative strategies that benefit smaller groups. Ketosis is likely one of those alternative strategies that works well for certain, smaller groups of people. So, right off the bat I want you to understand that Ketosis might not be for everyone. I’m going to lay out the case for potential benefits of Ketosis. If it sounds interesting and beneficial to you, then consider trying it. (see our free cheat sheet to help you). What is Ketosis Ketosis occurs when liver glycogen gets depleted and the body burns fatty acids for fuel. The primary driver of this state is a very low carbohydrate intake. Often, it also requires a low protein, higher fat intake. You can also achieve a state of ketosis by not eating altogether. The creation of ketones is a byproduct of this metabolic state. Ketones are a source of fuel, just as glucose is a source of fuel. Ketones tend to have some added benefits, though. What role does Ketosis play in human health? Ketosis allows our bodies to function in the absence of carbohydrates, both physically and mentally. Instead of burning carbohydrates, or converting protein to glucose, the body burns ketones. This is pretty much a survival mechanism. It allows your body to function in a state of caloric deprivation. This is why ketosis often gets bad press (as it’s linked to “starvation”). Being a survival mechanism doesn’t make it invalid as a strategy, though. There can still be potential benefits to be had. Let’s cover a few of them… Ketosis and Accelerated Fat Loss Being in ketosis Continue reading >>

The Ultimate Guide To A Ketogenic Diet

The Ultimate Guide To A Ketogenic Diet

Time to talk Keto. A Ketogenic Diet is a diet with very low or no carbohydrates. Any guide we make will cover everything we can think of to make this the single best resource around, and due to that, you may want to skip some sections. Like always, we will start with the history of this famous diet, get into some science, and blow you away with all the practical advice you will ever need. For those who want to skip ahead, we included a quick table of contents for this very long (6,000 words or so) article. The Legendary Beginning of the Atkins Diet I very well could have made several articles on the Atkins Diet alone. Yes, this is a fad diet. Unlike most fad diets (Cabbage soup, I am looking at you), the ketogenic diet is based on science. Albeit, the sciece of just one study. The story goes like his, the future Dr. Atkins stumbled upon a study in the Jama network, a leading scientific research collective. After reading the study, which was designed to test fat loss on a medical diet, Dr. Atkins invented the Atkins Diet around 1958. My beef with Atkins is the connection of Atkins to real ketogenic science. The connection is a well-known study by Dr. Wishnofsky. The study proved a diet high in fat, and with moderate protein will cause weight loss. The Atkins Diet claim was that this study demonstrated that you could lose weight without a caloric deficit if you eat the right magic meats and fats. Wait, Lose Weight Without a Caloric Deficit? Atkins claimed that the study proved you could lose weight without a caloric deficit. Is it true? Partly. Including water weight you drop from ketosis, you can lose weight without a caloric deficit. My problem with this is Dr. Wishnofsky never said this. The study was not about some magic weight loss combination. (Yes, I link to the st Continue reading >>

Why Your Diet Should Include More Fat

Why Your Diet Should Include More Fat

Think back to the '80s and '90s when buying anything that didn't don a low-fat label was simply taboo. Back then, butter and egg yolks topped the "do not eat" list, while refined carbs and packaged foods weren't given a second thought. But times have definitely changed. These days, experts tout fat as a must-have macro and full-fat products, like whole milk, avocado, ghee and coconut oil, join the ranks of superfoods. Yet, some people still question what kinds of fat they should eat and exactly how it affects the body. That's why we called on Mark Hyman, MD, author of the "Eat Fat, Get Thin Cookbook," to help us wipe clean the greasy mess of info and lay down the facts on fat. Reality: Even though this myth is the basis for low-fat diets and food products, it's far from the truth. Eating fat won't make you fat. Completely eliminating or limiting fat from your diet can actually make you gain weight, often because it leaves you feeling so deprived. Conversely, some studies have found that fatty foods can aid in weight loss. "The problem with most diets is that they lack the key ingredient that makes food taste good and cuts your hunger," says Dr. Hyman. And you guessed it, that's fat. "Healthy fats are the best source of energy for your body, and they keep your metabolism and fat-burning mechanisms running as they're meant to," Dr. Hyman explains. Research supports this, showing that a low-fat diet could slow down metabolism. So now you have permission to enjoy a spoonful of nut butter with an apple before your next workout or a satiating piece of steak for dinner every once in a while. Reality: Not so fast. While saturated fat has long been known as public health enemy number one, recent research proves it's not so scary. Of course, you shouldn't always opt for a meal fu Continue reading >>

Death From Dehydration Is Usually Serene

Death From Dehydration Is Usually Serene

Though the legal wrangling in the Terri Schiavo case has been loud and contentious, the brain-damaged woman's physical response to having her feeding tube removed is likely to be very serene. "The process of starving to death seems very barbaric but in actuality is very peaceful," said Dr. Fred Mirarchi, assistant clinical professor of emergency medicine at Drexel University College of Medicine in Philadelphia. "The patient's experience is really pretty benign," said Dr. Joanne Lynn, a hospice physician associated with Americans for Better Care of the Dying, a group working for improved end-of-life care. "Overwhelmingly, what will happen is nothing." Lynn, who has worked with numerous families facing end-of-life situations, said most patients who are removed from life support will die within a matter of a few days or weeks. "Some people can last four or five days -- some people can last 20 days," she said. Schiavo's feeding tube was removed March 18 following a contentious battle between her husband, who said his wife would not want to live in a vegetative state, and her parents, who wanted her kept on life support. Schiavo's feeding tube was removed twice before, in 2001 and 2003. The second time, the tube was replaced after six days when Florida Gov. Jeb Bush signed a hastily passed law allowing him to intervene in the case. "Terri's Law" was later ruled unconstitutional. The Body Begins Shutting Down The physical process of dying after life support is removed follows a pattern familiar to hospice workers. And the fact that Schiavo is in a vegetative state will likely make her death faster and less painful, Lynn said. "It depends on whether she has the ability to swallow anything -- and if that anything is offered," she said. "If she's unable to swallow anything, the Continue reading >>

New Mother Nearly Dies From A Low Carb Diet: 32-year-old Developed Life-threatening Condition After Ditching Bread, Rice And Pasta While Breastfeeding

New Mother Nearly Dies From A Low Carb Diet: 32-year-old Developed Life-threatening Condition After Ditching Bread, Rice And Pasta While Breastfeeding

A new mother developed a life-threatening condition due to eating a low carbohydrate diet while breastfeeding, doctors claim. The 32-year-old Swedish woman was rushed to hospital with nausea and vomiting, heart palpitations, trembling and spasms in her limbs. When questioned, she said she had been following a a strict low carbohydrate high fat diet (LCHF) in order to lose her baby weight, doctors describing her case in the Journal of Medical Case Reports said. The regime saw the woman, who is unidentified, eating less than 20g of carbohydrate day, the equivalent of a medium-sized potato, or a thick slice of toast, while breastfeeding her 10-month-old son. In the UK, adults are advised to get half of their daily energy intake from carbohydrates, according to a report by the Scientific Advisory Committee on Nutrition, who advise the Government. This is the equivalent of 200 - 240g of carbohydrates in a person eating 2,000 calories a day. The woman said she had lost 4kg on the diet but had begun to feel very ill. In hospital, medics carried out tests and discovered she was suffering from ketoacidosis, a rare but potentially life-threatening condition normally seen in people with type 1 diabetes. ‘The primary diagnosis was thought to be ketoacidosis due to starvation induced by the LCHF diet,’ doctors writing in the journal. When a person has raised blood glucose levels, or are eating a low carbohydrate diet, their body may go into a state of ketosis. Ketosis is a state the body goes into if it needs to break down body fat for energy. The state is marked by raised levels of ketones in the blood which can be used by the body as fuel. Ketones which are not used for fuel are excreted out of the body via the kidneys and the urine. In ketosis, the level of ketones in the blo Continue reading >>

Last Hours Of Living

Last Hours Of Living

Dying patient Last hours of live Transitioning Once transitioning process started, discuss the goals of care with family (may be patient if he is able to) Several patho-physiological changes occur as patient is transitioning Patient develops multiple signs & symptoms as they are getting closer to death The S/S are devastating to patients and staff & friends & family. Control each symptom effectively, May require contineous care, family / friends needs access to patients 24/7 Aggressive resuscitative measure are fruitless The degree of family distress seems to be inversely related to the extent to which advance planning & preparation occurred. Spending time in preparation of families is very worthwhile Physicians, nurses & hospice staff need to have a clear understanding of: signs & symptoms pathophysiology pharmacological / non-pharmacological approach changes encountered surrounding the dying process : Decreasing Appetite/Food Intake, Wasting, Decreasing Blood Perfusion, Renal Failure, Decreasing Level of Consciousness , Terminal Delirium, Loss of Ability to Swallow,Pain, declining in all aspects of life Weakness/Fatigue : functional decline Decreasing Fluid Intake, Dehydration Neurological Dysfunction: An Overview Loss of Sphincter Control Changes in Respiration Loss of Ability to Close Eyes Manage other s/s Most common S/S are: functional decline, dependent on all ADLs, anxiety, dyspnea, delirium, death rattle, nausea, worsening of discomfort / pain. Place of death: * 59-81% wants to die at home. * 20% of dying patients are having rough time due to transition between hospital / home/ nursing home/ assisted living facilities. *Recognize transitioning and help them die peacefully at home *45% of deaths occur under hospice care in USA * Place of death of hospice patient Continue reading >>

Cancer’s Ketogenic Kryptonite With Patricia Daly – #339

Cancer’s Ketogenic Kryptonite With Patricia Daly – #339

Why you should listen – Patricia Daly is a fully-qualified nutritional therapist based in Dublin, Ireland. Following her cancer diagnosis, she left her corporate career and started studying nutrition, specializing in the area of Integrative Cancer Care. As a Swiss native, she regularly attends training courses in Switzerland/Germany, including at the renowned Tumor Biology Center in Freiburg, Germany. She’s working on a new book on the benefits of the low carb and ketogenic diet, which she’s co-writing with Irish foodwriter Domini Kemp. On today’s episode of Bulletproof Radio, Patricia and Dave talk about the ketogenic diet, tips for battling cancer, lights to avoid, hormonal irregularities, grounding, her story of overcoming cancer and more. Enjoy the show! Watch Listen Follow Along with the Transcript! Dave: Looking for a career in tech, maybe business data design or marketing? Trying to get that promotion or raise to excel in your career? You need 21st century training and skills. General Assembly is the largest and most respected school worldwide for people seeking to grow their talents and master the marketplace. Whether it’s learning remotely online or in person at one of their beautiful campuses, you can join the 350,000 people who had already gone the training needed to propel careers in tech and business. More than 2500 companies worldwide hire GAs graduates with 99% of graduates who participate in GA’s career services lending a new role in their field within 6 months of starting their job search. Take control of your talent and career now. Find out more at ga.co/bullet that’s ga.co/bullet. Enter the promo code bullet to save on your first class workshop or event. That’s ga.co/bullet code word bullet. Speaker 1: Bulletproof Radio a station of hi Continue reading >>

Is The Ketogenic Diet Right For You? Nutritionists Weigh In

Is The Ketogenic Diet Right For You? Nutritionists Weigh In

You may be hearing a lot about the ketogenic diet as a way to slim down while noshing on butter and heavy cream. This way of eating is suddenly hot among venture capitalists in Silicon Valley, who believe it will help them live longer and healthier, CNBC reports. Some praise the high-fat/ultra low-carb plan for helping them to lose weight and have energy all day long. Other advocates say it finally helped them to get control of their body. How does it work and could it help you? We asked Bonnie Taub-Dix, a registered dietitian nutritionist and author of “Read It Before You Eat It”; and Keri Glassman, nutritionist, registered dietitian and TODAY Tastemaker. To start with, both said they would never advise the ketogenic diet for weight loss. “Cutting out carbs is usually an invitation to overeat them at another point,” Taub-Dix said. “For a diet where you’re looking to lose weight, look good and feel good… I would not recommend a diet like this.” “For safe and effective weight loss, the carb reduction is too extreme,” Glassman added. RELATED: Read inspiring stories of ordinary people slimming down in TODAY's My Weight-Loss Journey Here’s what you need to know: What is the ketogenic diet? It’s a diet fine-tuned in the 1920s to help treat epilepsy. It does help to control seizures in some children, but it’s not recommended for adults “mostly because the restricted food choices make it hard to follow,” the Epilepsy Foundation says. The diet has just recently begun to be touted as a weight loss plan, Glassman noted. She described it as eating “mostly fat with a teeny bit of protein and carbs.” How does it work? Your body normally relies on carbohydrates for energy. It breaks them down into glucose, which is your main source of fuel. If that Continue reading >>

Sudden Cardiac Death In Association With The Ketogenic Diet.

Sudden Cardiac Death In Association With The Ketogenic Diet.

Abstract The ketogenic diet is a high-fat, low-carbohydrate, adequate-protein diet that is used to decrease the frequency of seizures in patients who have refractory epilepsy. Despite its positive effects in some patients, there are potential adverse effects. Two complications related to the ketogenic diet are selenium deficiency, which has been associated with impaired myocardial function, and QT prolongation as documented on electrocardiography. Reported here are two cases of death in a child on the ketogenic diet for seizure control. In case 1, the child who died of complications related to torsade de pointes, with documented QT prolongation; post mortem examination revealed selenium-deficiency cardiomyopathy. In case 2, a child experienced QT prolongation while on the ketogenic diet and later died suddenly at home. Both children exhibited selenium deficiency. These two cases suggest that patients on the ketogenic diet require monitoring of the QT interval by electrocardiography, myocardial function by echocardiography, and selenium levels before and during the ketogenic diet. Continue reading >>

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