Acetone As Biomarker For Ketosis Buildup Capability - A Study In Healthy Individuals Under Combined High Fat And Starvation Diets
Go to: Ketosis or ketoacidosis is a physiological state sharing an outcome of increased ketone levels in the blood due to relatively high lipid oxidation rates. Monitoring rapid and dramatic changes in ketones offers us valuable diagnoses for lipid oxidation and metabolism [1]. Several studies have clearly demonstrated that metabolic imbalance in type I diabetes has led to ketoacidosis (KAD) of blood, leading to elevated ketone levels with arterial pH < 7.3 and bicarbonate < 15 mEq/L, and causing arresting of major organ functions [2]. In addition to acidosis, studies have also shown that elevated ketone levels are a natural metabolic response to negative energy balance, wherein caloric intake is smaller than total energy expenditure, and the body burns stored fat to produce the needed energy [3], leading to a state of ketosis known as fasting ketosis (FK). FK has been used as an indicator of the effectiveness of weight loss [4-6]. Furthermore, ketosis also occurs in situations where caloric intake equals total energy expenditure, specifically in a diet that contains high percentage of fat (>60%) and/or low carbohydrate. This state of ketosis has been referred to as nutritional ketosis (NK) [7,8]. NK has been investigated as a treatment for epilepsy because ketones are thought to provide energy to the brain, which reduces epileptic seizures [9,10]. In addition, ketosis buildup capability resulting from a combination of NK and FK has been associated with weight loss efficiency and positive health outcomes [11-13]. While KAD, FK, and NK are well-defined clinical and physiological states that can produce high levels of ketones, there are other conditions, such as exercise that can actually decrease ketone levels in the blood by using ketone as an energy source in the muscl Continue reading >>
10 Signs That You Might Be In Ketosis
Republished with permission from Authority Nutrition. Original article here. CHECK OUT SOME OF MY OTHER FAVORITE LOW CARB KETO RESOURCES: 10 Signs that you Might be in Ketosis The ketogenic diet is a popular, effective way to lose weight and improve health. When followed correctly, this low-carb, high-fat diet will raise blood ketone levels. These provide a new fuel source for your cells, and cause most of the unique health benefits of this diet (1, 2, 3). On a ketogenic diet, your body undergoes many biological adaptions, including a reduction in insulin and increased fat breakdown. When this happens, your liver starts producing large amounts of ketones to supply energy for your brain. However, it can often be hard to know whether you’re “in ketosis” or not. Here are 10 common signs and symptoms of ketosis, both positive and negative. 1. Bad Breath People often report bad breath once they reach full ketosis. It’s actually a common side effect. Many people on ketogenic diets and similar diets, such as the Atkins diet, report that their breath takes on a fruity smell. This is caused by elevated ketone levels. The specific culprit is acetone, a ketone that exits the body in your urine and breath (4). While this breath may be less than ideal for your social life, it can be a positive sign for your diet. Many ketogenic dieters brush their teeth several times per day, or use sugar-free gum to solve the issue. If you’re using gum or other alternatives like sugar-free drinks, check the label for carbs. These may raise your blood sugar levels and reduce ketone levels. The bad breath usually goes away after some time on the diet. It is not a permanent thing. Bottom Line: The ketone acetone is partly expelled via your breath, which can cause bad or fruity-smelling breat Continue reading >>
A Keto Diet For Beginners
A keto or ketogenic diet is a very low-carb diet, which turns the body into a fat-burning machine. It has many proven benefits for weight loss, health and performance, as millions of people have experienced already. 1 Here you’ll learn how to eat a keto diet based on real foods. You’ll find visual guides, recipes, meal plans and a simple 2-week get started program, all you need to succeed on keto. Get even more, custom meal plans, ask the experts and low-carb TV, with a free trial. 1. Introduction: What is ketosis? The “keto” in a ketogenic diet comes from the fact that it makes the body produce small fuel molecules called “ketones”. 2 This is an alternative fuel for the body, used when blood sugar (glucose) is in short supply. Ketones are produced if you eat very few carbs (that are quickly broken down into blood sugar) and only moderate amounts of protein (excess protein can also be converted to blood sugar). Ketones are produced in the liver, from fat. They are then used as fuel throughout the body, including the brain. The brain is a hungry organ that consumes lots of energy every day, 3 and it can’t run on fat directly. It can only run on glucose… or ketones. On a ketogenic diet, your entire body switches its fuel supply to run almost entirely on fat. Insulin levels become very low, and fat burning increases dramatically. It becomes easy to access your fat stores to burn them off. This is obviously great if you’re trying to lose weight, but there are also other less obvious benefits, such as less hunger and a steady supply of energy. When the body produces ketones, it’s said to be in ketosis. The fastest way to get there is by fasting – not eating anything – but nobody can fast forever. A keto diet, on the other hand, can be eaten indefinite Continue reading >>
How To Measure Ketosis? Breath Analyzer? Urine Strips?
How to measure ketosis? Breath analyzer? Urine strips? What is Reddit's opinion on breath analyzers? My keto strips consistently have color. Reddit says this does not mean anything. I see on other websites that a person can be in ketosis without any color in the strips, but I don't see anywhere else that says you can show color without being in ketosis. What is the cause of this? New comments cannot be posted and votes cannot be cast f/54/5'4"| SW: 235 |CW: 131.8 |GW: 145| GOOOOOAAAAALLLLLL!3 points 1 year ago This is the absolute best way to determine if you are in ketosis. 27M/5'3/SW:190/CW: 135/GW:1251 point 1 year ago Blood is the most accurate way, but it gets expensive. M/30/5'8" | SW 278 | CW 199 | GW 1702 points 1 year ago A good saying to keep in mind is "chase results, not ketones". There really is no reason to measure ketones, just stay under 20g of net carbs and you are in ketosis. Trying to chase ketones can just bring on anxiety as ketone levels naturally fluctuate. 27M/5'3/SW:190/CW: 135/GW:1251 point 1 year ago What's the point? Why do you want to measure? There's pretty much no reason to, 26/M/5'9" | 150 lbs Maintenance4 points 1 year ago They're a waste of money. Eat under 20g of carbs and you're in ketosis. Eat less than 20g of carbohydrates per day and you'll be in ketosis. No need to measure anything more than that. I think urine testing can mislead people and discourage them and that's why this sub generally disapproves. The urine strips can fail to indicate ketones (maybe they are faulty, expired, etc.) and they can indicate ketones but from fat that you ate not fat that you used off your body. I wouldn't agree that it "doesn't mean anything" but what it means beyond something in your urine activated the test strip, is up to you to analyze. A lot Continue reading >>
A Quick Rundown Of The Ketogenic Diet
By Kevin Farrell March 26, 2018 7:04 pm Follow @ikevinfarrell By Kevin Farrell | March 26, 2018 7:04 pm Follow @ikevinfarrell Keto, keto, keto! It seems like no matter where you turn these days, the trendy diet is a topic of conversation. This friend is starting a keto diet. That cousin has the keto flu. Charlie from the marketing department is counting his macros. What the heck does any of this even mean? Before you can decide if the keto diet is right for you, youve got to learn the lingo. Heres what you need to know: For starters, keto is short for ketogenic diet. Its a fancy way of saying low carbohydrate, or low carb/high fat (LCHF) diet. On a keto diet, breads are bad, fats are fine, and strictly monitored amounts of protein are a part of each meal. A post shared by Mark Bever (@mark.bever) on The core science behind keto revolves around glucose sugar in one of its simplest forms. When presented with glucose, your body is hardwired to focus its digestive capabilities on converting that sugar into energy. Critically, this means that other forms of potential energy namely fat are left untouched within your body. By avoiding carbs (and therefor simple sugars) almost entirely, keto aficionados manipulate their bodies into finding energy a few rungs down on their genetic wish lists instead. Thus, the bodys fat reserves are digested and converted into energy instead of stored on your midsection, thighs or other problem areas. That genetic process of fat-burning manipulation is called ketosis , and it is essentially the goal of the whole experience. Ketosis is basically an entirely different operating system that your body gear-shifts into when food is sparse. During this alternate metabolic state, your bodys fat reserves are plundered and sent to the liver for digestio Continue reading >>
The Effect Of A Low-carbohydrate, Ketogenic Diet Versus A Low-glycemic Index Diet On Glycemic Control In Type 2 Diabetes Mellitus
The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus Westman et al; licensee BioMed Central Ltd.2008 Dietary carbohydrate is the major determinant of postprandial glucose levels, and several clinical studies have shown that low-carbohydrate diets improve glycemic control. In this study, we tested the hypothesis that a diet lower in carbohydrate would lead to greater improvement in glycemic control over a 24-week period in patients with obesity and type 2 diabetes mellitus. Eighty-four community volunteers with obesity and type 2 diabetes were randomized to either a low-carbohydrate, ketogenic diet (<20 g of carbohydrate daily; LCKD) or a low-glycemic, reduced-calorie diet (500 kcal/day deficit from weight maintenance diet; LGID). Both groups received group meetings, nutritional supplementation, and an exercise recommendation. The main outcome was glycemic control, measured by hemoglobin A1c. Forty-nine (58.3%) participants completed the study. Both interventions led to improvements in hemoglobin A1c, fasting glucose, fasting insulin, and weight loss. The LCKD group had greater improvements in hemoglobin A1c (-1.5% vs. -0.5%, p = 0.03), body weight (-11.1 kg vs. -6.9 kg, p = 0.008), and high density lipoprotein cholesterol (+5.6 mg/dL vs. 0 mg/dL, p < 0.001) compared to the LGID group. Diabetes medications were reduced or eliminated in 95.2% of LCKD vs. 62% of LGID participants (p < 0.01). Dietary modification led to improvements in glycemic control and medication reduction/elimination in motivated volunteers with type 2 diabetes. The diet lower in carbohydrate led to greater improvements in glycemic control, and more frequent medication reduction/elimination than the low glycemic index diet. L Continue reading >>
7 Signs You Are In Ketosis
The Ketogenic Diet (also known as “keto”) has been all over social media. You’ve probably seen ripped fitness models claiming that Keto gave them their physique, and the even more inspiration stories of normal people like you and me, who lost weight and reclaimed their lives through this diet called Keto. If you’re not sure what the Ketogenic Diet is, head on over to What is a Keto Diet? (Ketogenic Diet 101). Over there I’ve detailed what exactly Keto is and isn’t, given you meal plans, snacks, and answered all of your questions about the diet. But let’s say you’ve jumped into Keto with both feet, and now you want to know “Is this working?” I don’t blame you. It can be hard to tell what’s going on inside your body. Are you in Ketosis? Are you eating few enough carbs? Are you shedding fat? Well, there are 7 obvious ways to tell if you’re in ketosis, without testing your blood or urine. Here are the signs you’re in Ketosis: 1. Weight Loss Weight loss is the first and most obvious sign that you’re in ketosis. The weight loss happens for a variety of reasons, but it’s important to note that it’s very fast in the beginning. This is because when you switch to a low-carb diet, your muscles start losing water. Carbohydrates are what bind water to your muscles, so when you’re not eating carbohydrates, your muscles start dumping them, and the attached water. That’s one of the things that causes Keto Flu (which you can read about in Keto 101), but drinking plenty of water and keeping your salt intake up will keep you hydrated and feeling healthy. After the initial water leaving your body, then you’ll start to see steady fat loss. Related Reading: My 60 Day Keto Challenge Results (I lost 23 pounds!) 2. Little or No Appetite When you stop eati Continue reading >>
Keto And Passing A Urine Drug Test - Backyard Science Edition (cross Post From R/ketotrees) - Keto
Keto and passing a urine drug test - backyard science edition (cross post from r/ketotrees) Hey all wanted to Xpost this just to get more data from the larger keto sub. if you have experience taking a THC drug test while in keto I would love to hear about it! I wanted to make this post because I haven't been able to find any good evidence to support my theory. The theory is essentially that if a marijuana user is on keto, the amount of time that marijuana will be detectable in urine will be significantly less than that of a smoker who is not on keto. I myself am not a regular smoker however recently I ate edibles once a day for roughly 1.5 months, all while maintaining a near constant state of ketosis (maybe a cheat day or two). I stopped using these edibles for roughly 1 week so I believe I should still be testing positive for THC in my urine, however a drug store first check drug test was negative for THC. Which may support my hypothesis. The broscience which led to my hypothesis is as follows. Keto forces the body to mobilize fat at a higher rate than a SAD. Because THC is lipophilic it remains in your fat cells getting released regularly after cessation of marijuana use, causing positive results in UA. Because fat is more mobilized during keto this should reduce the amount of time before THC levels fall below the levels necessary to result in a negative drug test. Think of it like a dam holding back a body of water. Where the water is the THC soaked fat cells. Opening the flood gates causes more water to flow out faster, draining the reservoir. There are problems with what I have done so far. Its one person and one test so far which is obviously not at all conclusive. Also when the test was performed I was intentionally NOT in ketosis, having cheated the day before Continue reading >>
Common Ketosis Side Effects And Treatments
There are many awesome benefits with come with adopting a low-carb ketogenic diet, such as weight loss, decreased cravings, and even possibly reduce diseases risks. That being said, it’s also good to talk about possible ketosis side effects so you know fully what to expect as you start this new health journey. Not everyone experiences side effects when starting a ketogenic diet, and thankfully, those who do don’t usually experience them for very long. It varies with the individual, but just to make sure all your bases are covered, we’re going to breaking down each possible side effect and go over ways to manage and alleviate them if needed. KETOSIS SIDE EFFECT 1 – Frequent Urination As your body burns through the stored glucose in your liver and muscles within the first day or two of starting a ketogenic diet, you’ll be releasing a lot of water in the process. Plus, your kidneys will start excreting excess sodium as the levels of your circulating insulin drop. Basically, you might notice yourself needing to pee more often throughout the day. But no worries; this side effect of ketosis takes care of itself once your body adjusts and is no longer burning through the extra glycogen. KETOSIS SIDE EFFECT 2 – Dizziness and Drowsiness As the body is getting rid of this excess water, it will also be eliminating minerals like potassium, magnesium, and sodium too. This can make you feel dizzy, lightheaded, and fatigued. Thankfully, this is also very avoidable; all it takes is a little preparation beforehand. Focus on eating foods that are rich in potassium, such as: Leafy greens (aim for at least two cups each day!) Broccoli Dairy Meat, poultry, and fish Avocados Add salt to your foods or use salty broth when cooking too. You can also dissolve about a teaspoon of regu Continue reading >>
Urine Ketone Levels 16 Mmol/l - Keto
Hi all, I just started ketoing about 1 month ago. Just did a urine test with DIRUI multistix and it showed my levels at 16 mmol/L. Is that too high? should i be worried? Some info:Male, 27 yrs. 180cm (5'11)Starting weight 93 kg (205 lbs)Current weight: 87 kg (191 lbs)Been eating 1500- 1900 calories a day.I am not diabetic, or atleast not a diagnosed one. I think you'll discover that most folks here eschew the urinalysis sticks, their accuracy is questionable due to many factors. Are you diabetic? If not, stick to your macros and chill out. Looks like you've lost a few lbs, that's awesome. Keep it up. Thanks for the reply. I find using the strips kinda reinforcing for my willpower (or maybe I have some kind of a piss fetish, i dont know) but in the future i will use them with a grain of salt. They usually falsely re enforce people. (Like they eat cake and still test that they ketones and go on to eat cake often ) They also discourage people cuz the people get low reading even though they are doing almost zero carb U would get the same results if u pissed on a crayon. A pissed on object ok im going to stop using those tests. and if i feel the urge to pee on something i will consider those crayons dont sweat the urine ones. they dont work that well, and even so, your body will eventually stop pissing out ketones on sustained ketosis. a blood test works way better, but those are like 100 bucks a box. M 61, 6'1" 1/1/15 SW 230 CW 203 GW 205 (muscle gain) Have your blood glucose checked If the fasting BG is over 200 at the same time with high high ketones go do emergency room - you might have diabetic ketoacidosis. Other reasons for this high urine keto levels are following. most often it is being kicked out of ketosis (cheat day) after you overeat on carbs your body switches Continue reading >>
The Fat-fueled Brain: Unnatural Or Advantageous?
Disclaimer: First things first. Please note that I am in no way endorsing nutritional ketosis as a supplement to, or a replacement for medication. As you’ll see below, data exploring the potential neuroprotective effects of ketosis are still scarce, and we don’t yet know the side effects of a long-term ketogenic diet. This post talks about the SCIENCE behind ketosis, and is not meant in any way as medical advice. The ketogenic diet is a nutritionist’s nightmare. High in saturated fat and VERY low in carbohydrates, “keto” is adopted by a growing population to paradoxically promote weight loss and mental well-being. Drinking coffee with butter? Eating a block of cream cheese? Little to no fruit? To the uninitiated, keto defies all common sense, inviting skeptics to wave it off as an unnatural “bacon-and-steak” fad diet. Yet versions of the ketogenic diet have been used to successfully treat drug-resistant epilepsy in children since the 1920s – potentially even back in the biblical ages. Emerging evidence from animal models and clinical trials suggest keto may be therapeutically used in many other neurological disorders, including head ache, neurodegenerative diseases, sleep disorders, bipolar disorder, autism and brain cancer. With no apparent side effects. Sound too good to be true? I feel ya! Where are these neuroprotective effects coming from? What’s going on in the brain on a ketogenic diet? Ketosis in a nutshell In essence, a ketogenic diet mimics starvation, allowing the body to go into a metabolic state called ketosis (key-tow-sis). Normally, human bodies are sugar-driven machines: ingested carbohydrates are broken down into glucose, which is mainly transported and used as energy or stored as glycogen in liver and muscle tissue. When deprived of d Continue reading >>
The Ultimate Guide To Ketone Testing
Ketone as a word has its root from an old German word, aketon, which means Acetone. Ketone is what your liver produces during the breakdown of fatty acids when your body is low on glucose. In simple words, when our body doesnt have enough glucose, the liver breaks down fatty acid to produce ketones. There are ways of measuring and determining what level ketones are in our body and one of this is the ketone test strip. Mistakes are often made between checking for ketones if you have diabetes and wanting to be on ketosis. Before anything else, it is important to know that they are completely different. When the cells in your body dont have enough carbohydrates from food to burn energy, it burns fat instead; in the process of burning fat, it produces ketones. A diabetic patient checks for ketones to know how much ketones he/she has in his/her urine or blood. Unlike checking for ketones, being in ketosis is a metabolic state whereby the body produces ketones, some organs make use of these ketones as fuel so that glycogen is only used by organs that depend on it. For people with diabetes, having high levels of ketones is considered to be dangerous, therefore, which is why it is important that they test for them to avoid and prevent getting into diabetic ketoacidosis (which we will explain later in the article). In this article, we will go through the importance of testing for ketones if you have diabetes, how and when to test for them using ketone strips, how to read the results and what do they mean. In addition, we will gloss over the advantages and disadvantages of testing ketones using strips instead of using the blood-based testing or the breathalyzer. It is important to test for ketone to know its level in the body. Levels of ketones could be high, low, normal or even Continue reading >>
How To Know If You Are In Ketosis Without Strips.
To know whether or not you’ve entered ketosis you can measure your blood ketone levels. But how to know if you are in ketosis without strips? Well, we’re already mildly ketogenic after an overnight fast. Once our liver glycogen stores have been depleted we begin to produce ketone bodies at an exponential rate. Despite that, it doesn’t mean that we’ll be utilizing them efficiently. If we’re not adapted, then our brain and muscles won’t be able to put those ketones into use. Nutritional ketosis begins if our blood ketone levels are over 0.5mMol. To indicate that, you can use either urine strips like Ketostix. There are also breath takers. The most optimal range for ketosis is between 0.5 and 3 mMol. Ketoacidosis occurs over 10mMol, which is quite hard to reach. It usually happens with people who are diabetic or after excessive alcohol consumption. But there are a few problems with measuring ketones. Having elevated levels of ketones doesn’t mean you’re in ketosis. These urine strips are expensive and taking several measurements a day is very costly. That’s why there’s another way how to know you’re in ketosis without strips. Like said, elevated ketone levels doesn’t necessarily mean ketosis. It might even be the opposite. If we’re not putting ketones into use, then we’re probably urinating it out. That’s why urine strips are not ideal. What we want to know as well is our blood sugar levels. Glucose and ketones are contradicting fuel sources. If one is elevated, then the other has to be decreased. If we have high blood sugar levels, then we won’t be able to use fat for fuel. We definitely won’t be in ketosis. Quantifying is great because it gives us an accurate interpretation of our condition. However, we shouldn’t get stuck with the dat Continue reading >>
Keto During Pregnancy
I get a ton of emails a few months after these consults telling me that they are ecstatic and are now pregnant but are wondering on what to eat now. As if this diet of REAL food would be harmful to a fetus. There are many reasons why to not add in certain foods like gluten and dairy. Many times when cravings get the best of pregnant clients and they consume these foods, the auto-immune response can result in a miscarriage. But even if the clients are committed about staying away from gluten and dairy, they often worry that too low of carbs is bad for the fetus. You will never find evidence of this, but you will read it all over the web. The information that clients read have a few flaws: 1. A huge mistake is when people and doctors compare benign dietary ketosis to diabetic ketoacidosis. You can produce ketones in a starvation state. So instead of using a well-formulated low carb diet, they starved pregnant rats to get them into ketosis. The flaw in that evidence should be obvious. 2. The last form of this “evidence” is when they sliced up the brains of rat fetuses and saturated them in ketones. What happened was that the brain cells lived but it stopped producing new brain cells. This is thought to be evidence that ketosis causes retardation. Now let’s dive into the facts. The lean human body is 74% fat and 26% protein by calories. Fats are a structural part of every human cell and the preferred fuel source of the mitochondria, the energy-burning units of each cell. A fetus naturally uses ketones before and immediately after birth. Many studies done on pregnant pigs that are placed on ketogenic diets have fetuses with “increased fetal brain weight, cell size and protein content. In the early stages of pregnancy there is an upsurge in body fat accumulation, whic Continue reading >>
Blog: My Six Week Ketogenic Diet Experiment
Disclaimer: The views expressed are those of the author and are not necessarily those of Catalyst. This blog is not meant in any way as medical advice. Please consult a medical profession before commencing any new eating regime. What would you say if I told you there’s a diet where you can eat all the food you normally deny yourself, stop counting tedious calories, shift some weight, gain extra muscle and get an energy boost too? If you’re anything like me you’d be asking ‘where do I sign up?’! So when I heard about the ketogenic diet from a colleague I was immediately intrigued. This simply sounded too good to be true. Could I really eat fat and get lean? Enjoy peanut butter treats and squeeze into my skinny jeans? Never one to shy away from a challenge, I decided to see for myself, and so my six week experiment with the ketogenic diet began….. So what actually is a ketogenic, or ‘keto’, eating plan? In its most simple form, this is an extremely low-carb, high-fat diet. By lowering your carb intake your body is pushed into a metabolic state known as ketosis (key –tow –sis), where your body switches from burning carbs as its primary energy source to burning fat. To be more precise, it uses ketone bodies or ketones from the breakdown of fatty acids in the liver. Hence the name, ketosis. Now fatty fuel can come from a meal you’ve just eaten or from the stores of fat on your body (aka, the evil muffin top). While it may sound a little questionable, ketosis is actually an entirely natural metabolic process that the body initiates to help us survive when our food intake is low. Typically our body runs on glucose derived from the breakdown of carbs – this is because glucose is the easiest molecule for the body to convert and use as energy, so it will b Continue reading >>
- Shankara Wellness Blog | Does Ayurveda Hold The Key To The Diabetes Problem In Children And Adults? - Shankara Wellness Blog
- The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus
- The Cost of Diabetes: Diabetes Blog Week 2017 // Day 2
