How Do You Know You Are In Ketosis?
I've not noticed any of these alleged ketosis symptoms and I've gone weeks without consuming carbs. This includes extended periods of fasting. I think I notice a few changes in mood during periods when I'm in extensive ketosis, but nothing that would suffice to serve as an indicator. I think it needs to be recognised that ketosis is not a binary in/out affair and also that just eating a high fat diet doesn't necessarily mean you'll be in deep ketosis. This table is fantastic. It shows that the levels of ketones in the blood vary as follows: 0.1 for a normal diet, up to 0.3 on a 12-24 hour fast, up to 1 during late pregnancy, 0.7-1 in a 5-10 day old baby, up to 2 post-exercise, 2-3 on a 48-72 hour fast, up to 3 on a high fat diet, 4-6 in late pregnancy after 48hours fasting and up to 25 in an untreated diabetic. I think this shows that eating high fat is not the be all and end all, and exercise and fasting are major factors and also that ketosis is not a radically unusual state, but rather something that neonates and pregnant women routinely enter (without bizarre symptoms). Notably the liver can hold up to 100-120g of carbohydrate, so you may not quickly enter ketosis after ceasing to eat carbs, your stored glycogen (and any excess protein) will see to your body's needs for some time. If, as is common among paleos, you're eating quite a lot of meat, then you'll be generating a lot of glucose endogenously- more than enough to limit ketosis (which seriously begins once you exceed more than 25% of calories from protein). Also I do wonder how low carb "very low carb, (no fruits)" is, since you can be extremely high carb without eating any fruit. If you really want to be sure you're in ketosis, then do some intense exercise and eat not too much protein and lots of coconut (w Continue reading >>
Metabolism And Ketosis
Dr. Eades, If the body tends to resort to gluconeogenesis for glucose during a short-term carbohydrate deficit, are those who inconsistently reduce carb intake only messing things up by not effecting full blown ketosis? If the body will still prefer glucose as main energy source unless forced otherwise for at least a few days, is it absolutely necessary to completely transform metabolism for minimal muscle loss? Also, if alcohol is broken down into ketones and acetaldehyde, technically couldn’t you continue to drink during your diet or would the resulting gluconeogenesis inhibition from alcohol lead to blood glucose problems on top of the ketotic metabolism? Would your liver ever just be overwhelmed by all that action? I’m still in high school so hypothetical, of course haha… Sorry, lots of questions but I’m always so curious. Thank you so much for taking the time to inform the public. You’re my hero! P.S. Random question…what’s the difference between beta and gamma hydroxybutyric acids? It’s crazy how simple orientation can be the difference between a ketone and date rape drug…biochem is so cool! P.P.S. You should definitely post the details of that inner mitochondrial membrane transport. I’m curious how much energy expenditure we’re talkin there.. Keep doin your thing! Your Fan, Trey No, I don’t think people are messing up if they don’t get into full-blown ketosis. For short term low-carb dieting, the body turns to glycogen. Gluconeogenesis kicks in fairly quickly, though, and uses dietary protein – assuming there is plenty – before turning to muscle tissue for glucose substrate. And you have the Cori cycle kicking in and all sorts of things to spare muscle, so I wouldn’t worry about it. And you can continue to drink while low-carbing. Continue reading >>
Ketosis Breath: Causes & Solutions For Bad Breath
Ultra-low carb diets have grown in popularity over recent years. These so-called “keto diets” aim to facilitate rapid weight loss, through the consumption of minimal carbohydrates. Keto diets have become understandably popular on account of their rapid results, together with the practical benefits of consuming healthy volumes of the right foods, making hunger less of a problem than on more typical calorie-controlled diets. However keto diets are not without their issues, and one of the most common complaints comes in the form of “ketosis breath”. Quite simply many individuals making use of very low carb diets suffer from pungent and unpleasant breath. The question is what can be done to counteract such a problem? The Cause of Ketosis Breath In order to learn how to get rid of keto breath, we first need to understand why breath can smell under such a regime. As it turns out there are two potential reasons(1), both of which can operate independently, or in conjunction. Ketone Release The most typical source of energy used by the body is glucose. This is typically derived from carbohydrates, where the digestive system breaks down complex sugars into simple glucose molecules. On very low carb diets, however, the body is unable to utilize such a fuel. Instead, the liver utilizes the fat present in the body as an energy source, producing “ketones” in the process(2). This is known as “ketosis” – and is the process from where keto diets get their unusual name. These ketone bodies come in three common forms; acetoacetate, beta-hydroxybutyrate and acetone(3). In large quantities they are removed from the body in the urine or through exhalation. Ketones can have quite a characteristic smell; they often make the dieter’s breath smell quite sweet and fruity, quit Continue reading >>
Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids. The two common ketones produced in humans are acetoacetic acid and β-hydroxybutyrate. Ketoacidosis is a pathological metabolic state marked by extreme and uncontrolled ketosis. In ketoacidosis, the body fails to adequately regulate ketone production causing such a severe accumulation of keto acids that the pH of the blood is substantially decreased. In extreme cases ketoacidosis can be fatal. Ketoacidosis is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Prolonged alcoholism may lead to alcoholic ketoacidosis. Ketoacidosis can be smelled on a person's breath. This is due to acetone, a direct by-product of the spontaneous decomposition of acetoacetic acid. It is often described as smelling like fruit or nail polish remover. Ketosis may also give off an odor, but the odor is usually more subtle due to lower concentrations of acetone. Treatment consists most simply of correcting blood sugar and insulin levels, which will halt ketone production. If the severity of the case warrants more aggressive measures, intravenous sodium bicarbonate infusion can be given to raise blood pH back to an acceptable range. However, serious caution must be exercised with IV sodium bicarbonate to avoid the risk of equally life-threatening hypernatremia. Cause Three common causes of ketoacidosis are alcohol, starvation, and diabetes, resulting in alcoholic ketoacidosis, starvation ketoacidosis, and diabetic ketoacidosis respectively. In diabetic ketoacidosis, a high concentration of ketone bodies is usually accomp Continue reading >>
How To Detect Ketosis
How can you tell if your low-carbing efforts have been effective enough to induce ketosis? Learn how to check your ketones! The state of ketosis The state of ketosis means that the body has switched from depending on carbohydrates for energy to burning fats for fuel. This means not only dietary fats (olive oil, guacamole, deep-fried pig ears), but also all the jiggly bits around your waist — clearly a desirable state for anyone looking to shed extra weight. When the body metabolizes fat, it generates molecules called ketones (also known as ketone bodies). As you restrict carbohydrate intake and amp up the dietary fat, more fat is metabolized and a greater quantity of ketones are created. Most of the cells in your body — including those in your brain — are able to use ketones for energy, although many people experience a few days’ adjustment period, often called the low carb flu. One of the varieties of ketones generated — acetone — cannot be used by the body and is excreted as waste, mostly in the urine and the breath. Conveniently, this makes it very simple to measure whether or not you are in ketosis. Upon entering ketosis, some people report a distinct change in the smell of their breath as a result of the extra released acetone. It could be “fruity” — it’s been likened to overripe apples — or even “metallic.” If you notice this happening during your first few days of changing your diet, it could be a good sign you’re in ketosis. The unusual smell isn’t anything dangerous, but it could be annoying. Drinking plenty of water should help, or get yourself some sugar-free gum. Most people report “keto-breath” diminishing after the first few weeks. Detecting ketones in urine The more accurate way — and the one we recommend — to check f Continue reading >>
Can A Low-carb Diet Make One's Urine Smell Bad?
Urine usually has little odor to it, so you may be puzzled if yours smells stronger than usual. A restrictive low-carb diet can put you into a state of ketosis, a side effect of which is a fruity-smelling urine. Moderate low-carb diets are unlikely to give your urine an unusual odor, however, so consider other causes and, if still not sure why your urine smells, consult your medical provider. Video of the Day It's unlikely that you'll reach the state of ketosis with moderately low-carb diets. You'll need to follow a restrictive plan, such as the Atkins 20™ diet, which only allows 20 grams of carbs per day, with virtually all high-carb foods off your plate. You focus on moderate amounts of protein and large amounts of fat. No added sugar, fruit, grains or starchy vegetables are allowed in a ketogenic diet. Meals consists of meats, cold-pressed oils and leafy, watery vegetables. Nuts, eggs and cheese serve as snacks. After several days or weeks of following this extremely low-carb plan, your body starts to produce ketones. You don't have enough carbs for energy, so, to fuel activity, your body becomes efficient at burning fat and the liver produces ketones to fuel the brain. This production is normal, but not regularly experienced by people that consume the 225 to 300 grams of carbohydrates recommended on a standard American 2,000-calorie diet. Benefits of the ketogenic diet include stabilization of blood sugar and insulin levels and the weight loss that results from your body reaching into your fat stores for energy. The diet may also help alleviate symptoms of a number of diseases, including neurological conditions and some cancers. Your Urine on Ketosis One of the first signs that you've reached a state of ketosis is frequent urination. As the diet stabilizes your in Continue reading >>
Ketosis symptoms are a result of the way the body gets rid of the excess ketone bodies which build up in the blood stream when a person eats a low carb, ketogenic diet. In short, the body has three ways of dealing with excess ketone bodies: First, the muscles liver and brain can burn them for energy in the cells. Second, the body can breathe ketones out through the lungs. And third, the body can flush ketones out through the kidneys and urine. Legionella Testing Lab - High Quality Lab Results CDC ELITE & NYSDOH ELAP Certified - Fast Results North America Lab Locations legionellatesting.com The ketosis symptoms associated with the benign dietary ketosis caused by eating a low carb, ketogenic diet are not dangerous. They may differ for each individual, with the most common symptoms being: Ketosis breath, which has a fruity odor, and the person in deep ketosis may feel a sort of slight burning in the nose and a slight smell of ammonia. Dry mouth, which is alleviated by drinking more regular tap or bottled water. (Reverse osmosis water will make this worse.) In the first week of beginning a ketogenic diet, most people experience frequent urination followed by fatigue, as insulin levels come down, and the kidneys release extraneous water stores. Minerals such as sodium, magnesium and potassium are also lost with excreted urine, and it is the mineral loss that causes the fatigue. This can be offset by eating more salt, drinking more fluids, and increasing the intake of magnesium and potassium containing foods. (Dairy foods and avocados are high in potassium, and you can drink broth for more sodium.) A slight headache at first which goes away in a few days. This is usually a sign of not getting enough salt. Ketone bodies become detectable in the urine. Ketone bodies are molecu Continue reading >>
Not to be confused with Ketoacidosis. Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis in which blood glucose provides energy. Ketosis is a result of metabolizing fat to provide energy. Ketosis is a nutritional process characterised by serum concentrations of ketone bodies over 0.5 mM, with low and stable levels of insulin and blood glucose. It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder. Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet (ketogenic diet), and deliberately induced ketosis serves as a medical intervention for various conditions, such as intractable epilepsy, and the various types of diabetes. In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is sometimes referred to as the body's "fat burning" mode. Ketosis and ketoacidosis are similar, but ketoacidosis is an acute life-threatening state requiring prompt medical intervention while ketosis can be physiological. However, there are situations (such as treatment-resistant Continue reading >>
What Is Ketosis?
What is ketosis? Being in ketosis is truly a magical thing. Ketosis happens when your body starts producing ketone bodies instead of utilizing carbohydrates as energy. Both can be used as energy sources, but I find that converting to a fat-burner over a carbohydrate-burner to be most favorable. Signs of being in ketosis There are a few signs that could suggest you’re in ketosis: a metallic taste in mouth strong smelling urine random bursts of happiness (it’s weird, but it’s true!) decreased appetite How to get into ketosis The best way to get into ketosis is to immediately drop all major carb sources in your diet and focus on high-quality fats. Some find that going extremely low carb for a couple days will jumpstart ketone production and ultimately reaching a state of ketosis. Initially when you first remove a majority of carbohydrates from your diet, most people experience signs of lethargy and flu-like symptoms. This is what people consider the “low carb flu.” The low carb flu could last anywhere from a couple days to a couple weeks. It’s important to stay extremely hydrated on a ketogenic diet, so much make sure you’re getting enough water and electrolytes. If you’re one of the lucky ones, you won’t experience any low carb flu symptoms at all. Carbohydrate tolerance varies from person to person to maintain a ketogenic state. Some report that they can eat up to 80 grams and still be in ketosis. A safe spot for most people seems to be between 20-30 grams. Benefits of being in ketosis You will find it hard to believe that an array of benefits can be obtained from following a ketogenic diet, but the proof is in the research! Some of these include: Effortless weight loss Awesome blood sugar regulation Reduced blood pressure Reduced inflammation Appetite Continue reading >>
Breath Acetone Is A Reliable Indicator Of Ketosis In Adults Consuming Ketogenic Meals1,2,3
Abstract Background: Ketogenic diets are used therapeutically to treat intractable seizures. Clinically, it appears that the maintenance of ketosis is crucial to the efficacy of the diet in ameliorating seizures. To understand how ketosis and seizure protection are related, a reliable, noninvasive measure of ketosis that can be performed frequently with minimal discomfort is needed. Objective: The objective was to determine which index, breath acetone or urinary acetoacetate, is more strongly related to the plasma ketones acetoacetate and β-hydroxybutyrate. Design: After fasting overnight for 12 h, 12 healthy adults consumed 4 ketogenic meals over 12 h. Blood, breath, and urine samples were collected hourly. Blood was analyzed for plasma acetoacetate and β-hydroxybutyrate, breath for acetone, and urine for acetoacetate. Results: By the end of the 12-h dietary treatment, plasma acetoacetate, plasma β-hydroxybutyrate, and breath acetone had increased 3.5-fold, whereas urinary acetoacetate increased 13-fold when measured enzymatically and 25-fold when measured with urinary ketone dipsticks. Plasma acetoacetate was best predicted by breath acetone (R2 = 0.70, P < 0.0001). Plasma β-hydroxybutyrate was equally predicted by breath acetone and urinary acetoacetate (R2 = 0.54, P = 0.0040). Conclusions: Breath acetone is as good a predictor of ketosis as is urinary acetoacetate. Breath acetone analysis is noninvasive and can be performed frequently with minimal discomfort to patients. As an indicator of ketosis in epilepsy patients consuming a ketogenic diet, breath acetone may be useful for understanding the mechanism of the diet, elucidating the importance of ketosis in seizure protection, and ultimately, enhancing the efficacy of the diet by improving patient monitoring. I Continue reading >>
10 Signs And Symptoms That You're In Ketosis
The ketogenic diet is a popular, effective way to lose weight and improve health. When followed correctly, this low-carb, high-fat diet will raise blood ketone levels. These provide a new fuel source for your cells, and cause most of the unique health benefits of this diet (1, 2, 3). On a ketogenic diet, your body undergoes many biological adaptions, including a reduction in insulin and increased fat breakdown. When this happens, your liver starts producing large amounts of ketones to supply energy for your brain. However, it can often be hard to know whether you're "in ketosis" or not. Here are 10 common signs and symptoms of ketosis, both positive and negative. People often report bad breath once they reach full ketosis. It's actually a common side effect. Many people on ketogenic diets and similar diets, such as the Atkins diet, report that their breath takes on a fruity smell. This is caused by elevated ketone levels. The specific culprit is acetone, a ketone that exits the body in your urine and breath (4). While this breath may be less than ideal for your social life, it can be a positive sign for your diet. Many ketogenic dieters brush their teeth several times per day, or use sugar-free gum to solve the issue. If you're using gum or other alternatives like sugar-free drinks, check the label for carbs. These may raise your blood sugar levels and reduce ketone levels. The bad breath usually goes away after some time on the diet. It is not a permanent thing. The ketone acetone is partly expelled via your breath, which can cause bad or fruity-smelling breath on a ketogenic diet. Ketogenic diets, along with normal low-carb diets, are highly effective for losing weight (5, 6). As dozens of weight loss studies have shown, you will likely experience both short- and long Continue reading >>
Ketosis: What Is Ketosis?
Ketosis is a normal metabolic process. When the body does not have enough glucose for energy, it burns stored fats instead; this results in a build-up of acids called ketones within the body. Some people encourage ketosis by following a diet called the ketogenic or low-carb diet. The aim of the diet is to try and burn unwanted fat by forcing the body to rely on fat for energy, rather than carbohydrates. Ketosis is also commonly observed in patients with diabetes, as the process can occur if the body does not have enough insulin or is not using insulin correctly. Problems associated with extreme levels of ketosis are more likely to develop in patients with type 1 diabetes compared with type 2 diabetes patients. Ketosis occurs when the body does not have sufficient access to its primary fuel source, glucose. Ketosis describes a condition where fat stores are broken down to produce energy, which also produces ketones, a type of acid. As ketone levels rise, the acidity of the blood also increases, leading to ketoacidosis, a serious condition that can prove fatal. People with type 1 diabetes are more likely to develop ketoacidosis, for which emergency medical treatment is required to avoid or treat diabetic coma. Some people follow a ketogenic (low-carb) diet to try to lose weight by forcing the body to burn fat stores. What is ketosis? In normal circumstances, the body's cells use glucose as their primary form of energy. Glucose is typically derived from dietary carbohydrates, including: sugar - such as fruits and milk or yogurt starchy foods - such as bread and pasta The body breaks these down into simple sugars. Glucose can either be used to fuel the body or be stored in the liver and muscles as glycogen. If there is not enough glucose available to meet energy demands, th Continue reading >>
Ketosis, The Weight-loss Key To The Atkins Diet, Does Work, But At A Price
Robert Atkins’ contentious death cast doubt on his already-controversial namesake diet. But he was onto something, apparently, because aspects of his high-fat regimen live on. Ketosis, a low-carb eating plan, promises to make people really thin, really quickly. Going keto is now a fad diet of its very own — look how good LeBron James looks! — despite concerns about its safety. In the world of crash diets, instant gratification is king, and ketosis appears to deliver rapid weight loss at full speed. That is, if you’re willing to take the risks. Phase one of the Atkins Diet had banked on ketosis, the body’s so-called “fat-burning” mode, which seemed to live up to the hype. Under normal conditions, the body fuels itself by burning up carbohydrates, fats, and protein, in that order. That’s because the simple sugars contained in pasta, rice, and sugar are easier molecules to break down. But if your body has no linguine to digest and is desperate for game fuel, it has no choice but to burn up the fat you’ve got on hand (or on love handles). And isn’t that the weight-loss dream? But ketosis is so-named because going low-carb causes the liver to break down fats into molecules called ketones, which can also be used a fuel source. The problem is, having too many ketones floating around can be dangerous. Diabetics unable to control their insulin levels can enter a state called ketoacidosis, when the buildup of ketones causes the blood to become dangerously acidic, which in turn messes with your organs. (At this point, ketones spill over into the urine, giving it a characteristic fruity smell. The term diabetes mellitus roughly means “pissing honey.”) Supporters of the Atkins Diet contend that the amount of ketones present in the blood during ketosis isn’t Continue reading >>
Low-carb Diets Can Cause Bad Breath
Low-carb diets may be good for your waistline, but you might not be able to say the same for your breath. Low-carb lifestyle junkies are more likely to suffer from a seldom discussed side effect of such diets -- halitosis, aka bad breath. And since more than 25 million people say they have tried the Atkins diet (not to mention other low-carb eating plans), according to the National Marketing Institute, bad breath may be an epidemic! Bad breath in the low/no-carb sect is often caused by certain chemicals that are released in the breath as the body burns fat. They are called ketones, and entering into a fat-burning state of ketosis is the hallmark of the Atkins diet. So the good news is that if your breath stinks, you're probably doing a good job of sticking to that low-carb diet. "Carbohydrates aren't readily available, so you start to use other fats and proteins as your source of energy, and as a result you are going to get a breath problem," explains Kenneth Burrell, DDS, the senior director of the council on scientific affairs of the American Dental Association. Pass the Bread? This is not an oral hygiene problem, Burrell says, so "all the brushing, flossing, and scraping of the tongue that you can do is not possibly enough to overcome this." The bottom line is that you must "reconsider the diet and modify it so this doesn't happen," he says. Sure, "there may be some ways to mask it by using mouthwashes, but you can't overcome the fundamental problem other than by changing the diet -- or at least introducing some carbohydrates." "It's a difficult problem to solve because if one uses any sucking candy or lozenge, one has to be careful that it has no sugar in it" as sugar is a big no-no on many low-carb eating plans, says S. Lawrence Simon, DDS, a New York City periodon Continue reading >>
Am I In Ketosis? The Symptoms And Signs Of Ketosis.
One of the questions people who are new to the LCHF (keto/ketogenic/low carb) diet frequently ask me is: how do I know if I’m in ketosis? What are the main signs of ketosis? Everyone’s different and while some may experience all of the symptoms of ketosis, some might only feel a couple of them. Some feel none at all. There are basic signs and symptoms that indicate that you’re in ketosis. But please note that I’m differentiating between the signs of keto flu (covered in the post I’m linking to) that many experience in the first days of a ketogenic diet, and the feeling of being in ketosis when the flu has subsided: Dry mouth (eat more salt and drink more water to alleviate this). See my keto breath article here. Weight loss. Yay! Metallic taste in your mouth or a strange taste in the back of your throat. Some describe it as fruity or a little sweet. A kind of “buzzing” feeling that’s hard to describe. Almost euphoric at times. Different kind of urine smell, stronger too! “Ketosis breath” – It can range from being a little sweet to being almost like you’ve had a drink of alcohol. Less appetite. You can go for hours without eating and don’t feel very hungry. Increased energy. If you don’t experience it try to eat more fat. Also, drink more water and watch your electrolytes. A ketone strip you pee on shows a positive result. There are also blood ketone meters, or the popular ketone breath test, that give a more specific result. (Pro-tip: If you get the pee strips, cut them in half ) But do note that even with a positive pee strip it’s not 100% certain that you’re in ketosis. A very dark positive result may only indicate that you’re dehydrated. For me personally, the main signs of ketosis are hard to miss. I just feel different! It’s hard Continue reading >>