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Ketosis Pregnancy Symptoms

Case Of Nondiabetic Ketoacidosis In Third Term Twin Pregnancy | The Journal Of Clinical Endocrinology & Metabolism | Oxford Academic

Case Of Nondiabetic Ketoacidosis In Third Term Twin Pregnancy | The Journal Of Clinical Endocrinology & Metabolism | Oxford Academic

We provided appropriate management with fluid infusion after cesarean delivery. The patient and her two daughters survived, and no disabilities were foreseen. Alcohol, methanol, and lactic acid levels were normal. No signs of renal disease or diabetes were present. Pathological examination revealed no abnormalities of the placentae. Toxicological tests revealed a salicylate level of less than 5 mg/liter, an acetaminophen level of less than 1 mg/liter, and an acetone level of 300 mg/liter (reference, 520 mg/liter). We present a case of third term twin pregnancy with high anion gap metabolic acidosis due to (mild) starvation. Starvation, obesity, third term twin pregnancy, and perhaps a gastroenteritis were the ultimate provoking factors. In the light of the erroneous suspicion of sepsis and initial fluid therapy lacking glucose, one wonders whether, under a different fluid regime, cesarean section could have been avoided. Severe ketoacidosis in the pregnant woman is associated with impaired neurodevelopment. It therefore demands early recognition and immediate intervention. A 26-yr-old patient was admitted to our hospital complaining of rapid progressive dyspnea and abdominal discomfort. She was pregnant with dichorial, diamniotic twins for 35 wk and 4 d. Medical history showed that she was heterozygous for hemochromatosis. Two years before, she had given birth to a healthy girl of 3925 g by cesarean section, and 1 yr before, she had had a spontaneous abortion. Her preadmission outpatient surveillance revealed slightly elevated blood pressure varying from 132158 mm Hg systolic and 7995 mm Hg diastolic. Glucose and glycosylated hemoglobin were tested at 24 wk and were normal at 4.6 mmol/liter and 5.4% (36 mmol/mol), respectively. Urine analysis at the outpatient obstetri Continue reading >>

8 Coconut Ketogenic Diet Benefits

8 Coconut Ketogenic Diet Benefits

Coconut Ketogenic Diet | Keto Diet Coconut Oil | Coconut Ketogenic Diet Plan | Coconut Oil Diet Benefits I’m a coconut lover. I love its sweet taste and how it adds richness to food. I like young coconuts, they’re cool and refreshing and I take it as a dessert. Coconut water? Yeah, I’m a sucker too. I think it is the most satisfying drink during the hot season. The love affair doesn’t stop there. It has a sweet aroma too. Adding it to your baked goodies can create happiness in the oven and staying on a coconut ketogenic diet is easier than you think. Coconut Ketogenic Diet: Good Or Bad Saturated fats (SFAs) should be in abundance in your diet if you plan to go on keto. Saturated fats in coconuts are called palmitic, myristic, and lauric acids. They are considered taboo among traditional dieters and they have been linked to coronary heart diseases because they can raise bad cholesterol (LDL levels) and clog the arteries. The same is true for other tropical oils like palm and kernel oils. Research has shown that coconut oil has even more saturated fats than animal fats like butter. More recent studies, however, show that saturated fats in coconut oil actually raise good cholesterol (HDL levels) and even considered cardio protective. Role In Weight Loss The keto diet is creating traffic on the internet nowadays. People are curious on how this diet helps some celebrities lose so much weight. Do you know how we can lose fat and weight more rapidly? Answer: coconut ketogenic diet. Coconut is not just SFA. It’s also MCT. MCTs, as in Medium-chain triglycerides, are natural sources of essential healthy fats. The good news about MCTs is that they can be immediately absorbed and digested by the body. Making you feel energized right away and for a long time. They are ther Continue reading >>

Pregnancy Toxaemia And

Pregnancy Toxaemia And

Contents Industry Background Management Nutrition Animal Health Breeding Fibre Production Fibre Marketing Meat Production and Marketing Pasture and Weed Control Economic Analysis Tanning Skins ketosis in goats The diseases pregnancy toxaemia and ketosis can cause severe problems in goats. While the diseases are clinically different and occur during different stages of pregnancy and lactation, the basis of the disorder is essentially the same: a decrease in blood sugar levels and an increase in ketones. In ruminants, glucose is synthesised mainly from propionic acid (a volatile fatty acid produced in the rumen) and from amino acids. The amount of glucose that is absorbed directly depends on how much dietary carbohydrate escapes rumen fermentation and is digested in the small intestine. This form of glucose uptake varies with different feeds as well as their treatment. Ruminants can use products from rumen fermentation, such as volatile fatty acids, for most of their energy requirements. However, the nervous system, kidneys, mammary gland and foetus have a direct requirement for glucose. During periods of peak glucose requirement (late pregnancy and early lactation) problems may arise due to a glucose deficiency. The incidence of pregnancy toxaemia and ketosis varies with the two main types of goats. In dairy goats with a genetic potential for high milk production, ketosis may be a potential problem; in non-milch goats (Angora, Cashmere and meat) pregnancy toxaemia is more common. PREGNANCY TOXAEMIA Main causes The most important cause of pregnancy toxaemia is a decline in the plane of nutrition during the last six to eight weeks of pregnancy. This places the pregnant female in a difficult situation because the developing foetus imposes an unremitting drain on available m Continue reading >>

Is Keto Dangerous While Pregnant, Breastfeeding, Or For Children?

Is Keto Dangerous While Pregnant, Breastfeeding, Or For Children?

A question I’ve come across seemingly increasingly in the past few months, is a variation of, is it safe for kids to eat keto, including women during pregnancy and breastfeeding? This is where a simple disambiguation between a well and poorly formulated diet should end the discussion but let’s dig a little bit deeper into the concerns themselves, studies on children, the validity thereof, what a good diet is and context. One of the applications of a well formulated ketogenic diet has been in treatment of PCOS with much success, though more research is needed. You can search for yourself to find more info on this and the specifics with lots of other blogs and anecdotes covering it out there, but between weight loss and improved hormone regulation from better food choices it’s a way to manage symptoms and issues associated with the disorder. Many women who see improvements have noted they end up with a surprise pregnancy after starting low carb. Though usually planned or at least semi-planned, you can find near endless anecdotes of despite several years of trying, a sudden ketobaby happened after a few weeks or months of low carb. Just search through //www.reddit.com/r/xxketo and /r/ketobabies for personal accounts thereof. If you’ve done prior research into keto, you should already know that improvements in endocrine function are one of the benefits with plenty of evidence to support it. So if you’ve found yourself with a surprise baby thanks to keto the next question is, can you, should you, or is it dangerous to continue while pregnant? Ketosis and Pregnancy: Thanks to Japan and low carb as a treatment for diabetes we do have some research done regarding the application of a low carb diet in pregnant mothers on ketone levels and their role. Aside from this, c Continue reading >>

Pregnancy Toxaemia In Sheep

Pregnancy Toxaemia In Sheep

Sheep Diseases Pregnancy Toxaemia Also known as: Ketosis, Toxaemia Pregnancy toxaemia is a common metabolic disorder of ewes that is caused by the increased energy requirements in the late stage of pregnancy being greater than the energy provided by the diet consumed. It occurs in sheep usually carrying multiple foetuses. It is widespread and may affect any age or breed of pregnant ewe. Ewes in over-fat or very poor condition are most at risk. While many factors contribute to body condition, ewes which are in poor body condition at mating are invariably in low condition during late pregnancy and are predisposed to pregnancy toxaemia. Pregnancy toxaemia is characterised by hypoglycaemia[/tooltip] and hyperketonaemia resulting in the animal being unable to maintain an adequate energy balance (Cal-Pereyra et al., 2015). There are two factors involved in the development of hypoglycaemia. The glucose requirement of the uterus may increase to more than 40% of the total liver glucose output (Lindsay and Oddy, 1985). This situation may be exacerbated by the limited feed intake of the ewe due to the volume of the uterus in late pregnancy. (DMI decreases from 1.54 kg at day 130 to 1.25 kg at day 145 of pregnancy). The endocrinological status of the ewe changes in late pregnancy. The lower circulating levels of insulin, together with higher levels of growth hormone, progesterone and prolactin in late pregnancy, tend to encourage hypoglycaemia (Vernon et al., 1981). Hypoglycaemia is usually followed by hyperketonaemia (Scott and Woodman, 1993). This is due to increased fat mobilisation (fat released from stores to be converted into energy). The resulting ketone bodies can be used as a source of energy, but excess will result in hyperketonaemia, which in the toxaemic ewe is accompan Continue reading >>

Ketosis

Ketosis

Not to be confused with Ketoacidosis. Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis in which blood glucose provides energy. Ketosis is a result of metabolizing fat to provide energy. Ketosis is a nutritional process characterised by serum concentrations of ketone bodies over 0.5 mM, with low and stable levels of insulin and blood glucose.[1][2] It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides[3]). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate,[4] and the levels of ketone bodies are regulated mainly by insulin and glucagon.[5] Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder. Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet (ketogenic diet), and deliberately induced ketosis serves as a medical intervention for various conditions, such as intractable epilepsy, and the various types of diabetes.[6] In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed.[5][7] For this reason, ketosis is sometimes referred to as the body's "fat burning" mode.[8] Ketosis and ketoacidosis are similar, but ketoacidosis is an acute life-threatening state requiring prompt medical intervention while ketosis can be physiological. However, there are situations (such as treatment-resistant Continue reading >>

Ketosis During Pregnancy – Is It Safe?

Ketosis During Pregnancy – Is It Safe?

Ketosis is a state of metabolism in adults where the energy is supplied to the body by ketones present in the blood rather than glycolysis, where the energy comes from glucose. People often land up in a dilemma while judging whether ketosis is safe during pregnancy or not. The diet of a woman has to undergo certain changes in case she nears pregnancy. However, you should be aware of the effects of ketosis before you opt for such a diet. The body of a woman undergoes a lot of changes during pregnancy. Food choices are important when she tries to conceive. Here, you will have a detailed information about ketosis before and during pregnancy. Ketosis before Pregnancy Although people think that ketosis during pregnancy is harmful, in reality, it can help you get pregnant. If you want to draw your energy from ketone particles, you should plan a ketogenic diet. For an ordinary person, it is safe and even women trying to get pregnant can stick to such a meal. These meals are low-carb diets, and people can switch to these diets when they get pregnant. Well, it is important to know that ketosis is safe before you get pregnant. However, the norms are a bit different during pregnancy and you should stick to the rules. Read on to know whether it is safe during pregnancy or not. If you had heard that ketosis is harmful during pregnancy, you might be confusing it with diabetic ketoacidosis (DKA). This is completely different from ketosis that we are speaking of here. DKA has no relevance with nutritional ketosis and it is a far more harmful syndrome. It occurs in diabetic people where the level of insulin is not managed properly. It disrupts the balance of acid and base in the body. The level of blood sugar in the case of DKA is around three times the normal conditions. This situation Continue reading >>

A Beginner’s Guide To The Ketogenic Diet: An Effective Way Of Optimizing Your Health

A Beginner’s Guide To The Ketogenic Diet: An Effective Way Of Optimizing Your Health

Many Americans suffer from various chronic diseases such as diabetes and obesity, and the main culprit is usually the food they eat. The standard American diet contains excessive amounts of protein and carbohydrates, neither of which is good for your health because it eventually causes you to develop insulin and leptin resistance. As a result, you gain excess weight, develop inflammation and become prone to cellular damage. To avoid this problem, significant changes in your diet are necessary, and the best way is inducing your body into a state of nutritional ketosis, a condition where your body burns fat as its primary fuel instead of sugar. In order to reach nutritional ketosis, you must follow a ketogenic diet. But what exactly is a ketogenic diet? This guide will tell you everything you need to know about a ketogenic diet – how you can apply it to your lifestyle and what positives you can reap from it. The Various Benefits of the Ketogenic Diet A ketogenic diet is a dietary approach that focuses on minimal carbohydrates, moderate amounts of protein and high healthy fat consumption — the three keys to achieving nutritional ketosis. In fact, it’s what I recommend for most people who would like to optimize their health. There are many reasons why you should try a ketogenic diet. It can be very beneficial for people suffering from chronic conditions, or for people who would simply like to be healthier than their current state. You’ll be excited to know that a ketogenic diet can help with the following: • Weight loss If you’re trying to lose weight, then a ketogenic diet is one of the best ways to do it, because it helps access your body fat so that it can be shed. Obese people in particular can benefit from this method. In one study, obese test subjects were Continue reading >>

Ketosis: Symptoms, Signs & More

Ketosis: Symptoms, Signs & More

Every cell in your body needs energy to survive. Most of the time, you create energy from the sugar (glucose) in your bloodstream. Insulin helps regulate glucose levels in the blood and stimulate the absorption of glucose by the cells in your body. If you don’t have enough glucose or insufficient insulin to get the job done, your body will break down fat instead for energy. This supply of fat is an alternative energy source that keeps you from starvation. When you break down fat, you produce a compound called a ketone body. This process is called ketosis. Insulin is required by your cells in order to use the glucose in your blood, but ketones do not require insulin. The ketones that don’t get used for energy pass through your kidneys and out through your urine. Ketosis is most likely to occur in people who have diabetes, a condition in which the body produces little or no insulin. Ketosis and Ketoacidosis: What You Need To Know Ketosis simply means that your body is producing ketone bodies. You’re burning fat instead of glucose. Ketosis isn’t necessarily harmful to your health. If you don’t have diabetes and you maintain a healthy diet, it’s unlikely to be a problem. While ketosis itself isn’t particularly dangerous, it’s definitely something to keep an eye on, especially if you have diabetes. Ketosis can be a precursor to ketoacidosis, also known as diabetic ketoacidosis. Ketoacidosis is a condition in which you have both high glucose and high ketone levels. Having ketoacidosis results in your blood becoming too acidic. It’s more common for those with type 1 diabetes rather than type 2. Once symptoms of ketoacidosis begin, they can escalate very quickly. Symptoms include: breath that smells fruity or like nail polish or nail polish remover rapid breat Continue reading >>

Ketosis (pregnancy Toxemia)

Ketosis (pregnancy Toxemia)

Ketosis, or Pregnancy Toxemia, in goats generally occurs within the last few weeks of pregnancy. Common symptoms include loss of appetite, spastic motion, twitching ears, edema and inability to stand. Labored breathing, coma and death can result without a quick diagnosis and effective treatment. Provide a sufficient, balanced diet with no sudden or drastic changes, high quality hay and a correct amount of grain daily, tailored to breed and condition, and at regular hours. Ensure that the doe does not have an excessive worm load and allow access to fresh water and loose minerals at all times. Exercise is also essential to build strong bodies and good appetites. At the onset of any symptoms the Keto-Nia Drench or several pumps of Nutri Drench daily can reverse the condition. More information on Ketosis / Pregnancy Toxemia: Supplies for prevention and treatment can be found here and include: Continue reading >>

Ketosis In Goats: What Is It And How To Prevent It?

Ketosis In Goats: What Is It And How To Prevent It?

Inside: Ketosis in goats: how to prevent this condition, the symptoms and the treatment. It is preventable and you can help your goat avoid it. This is one post in our Raising Goats series.  Although I worked in an Alzheimer home in Boise when I was going to school, I can’t say that I had or gained a passion for the medical side of life. Truly, it was a wonderful experience working with and helping the residents but it wouldn’t become a long-term profession. So, when I first heard the word “ketosis”, I said, “huh??” But it is an important term to know when you are dealing with goats who have recently kidded and their health. As a goat owner, it is your primary responsibility to provide your goats with adequate nutrition so that you never have to work on the treatment side of these problematic conditions. Let’s start off by answering the question: It is a metabolic condition after kidding Ketosis is a metabolic problem caused by an animal living on its own body reserves because it has stopped eating food. The higher nutritional needs of a doe continue as they did in the last weeks of her pregnancy because now she is producing large quantities of milk. So a doe in the early stages of lactation may experience a net loss of energy. Usually, four to six weeks after kidding, the doe’s hormonal stimuli for lactation overcomes the effects of inadequate food intake. Ketosis in goats can be a very detrimental condition for your herd. What else do you need to know about this condition? • Prevention is key: • Never should the doe be excessively fat. • Any changes in diet should be introduced slowly. The addition of protein grain concentrate not only is important for the health of the doe and kid during pregnancy but for the health of the goat as she begins l Continue reading >>

Overview Of Ketosis In Cattle

Overview Of Ketosis In Cattle

(Acetonemia, Ketonemia) By Thomas H. Herdt, DVM, MS, DACVN, DACVIM, Professor, Department of Large Animal Clinical Sciences and Diagnostic Center for Population and Animal Health, Michigan State University Ketosis is a common disease of adult cattle. It typically occurs in dairy cows in early lactation and is most consistently characterized by partial anorexia and depression. Rarely, it occurs in cattle in late gestation, at which time it resembles pregnancy toxemia of ewes (see Pregnancy Toxemia in Ewes and Does). In addition to inappetence, signs of nervous dysfunction, including pica, abnormal licking, incoordination and abnormal gait, bellowing, and aggression, are occasionally seen. The condition is worldwide in distribution but is most common where dairy cows are bred and managed for high production. Etiology and Pathogenesis: The pathogenesis of bovine ketosis is incompletely understood, but it requires the combination of intense adipose mobilization and a high glucose demand. Both of these conditions are present in early lactation, at which time negative energy balance leads to adipose mobilization, and milk synthesis creates a high glucose demand. Adipose mobilization is accompanied by high blood serum concentrations of nonesterified fatty acids (NEFAs). During periods of intense gluconeogenesis, a large portion of serum NEFAs is directed to ketone body synthesis in the liver. Thus, the clinicopathologic characterization of ketosis includes high serum concentrations of NEFAs and ketone bodies and low concentrations of glucose. In contrast to many other species, cattle with hyperketonemia do not have concurrent acidemia. The serum ketone bodies are acetone, acetoacetate, and β-hydroxybutyrate (BHB). There is speculation that the pathogenesis of ketosis cases oc Continue reading >>

Pregnancy Disease (ketosis, Pregnancy Toxemia)

Pregnancy Disease (ketosis, Pregnancy Toxemia)

Pregnancy disease is the most common metabolic disease of sheep. It affects improperly fed ewes in late pregnancy. Often it is observed in overly fat ewes and ewes in poor condition. Almost always, affected ewes are carrying twins or triplets. It is generally accepted that the basic cause of pregnancy disease is a carbohydrate metabolism disturbance that is associated with, or results in, low sugar levels, ketosis, depressed liver glycogen, and fatty infiltration of the liver. The disease is usually fatal. From 60 to 80 percent of the growth of the fetus occurs during the last six weeks of pregnancy. If twins are present, the increase in total weight is considerable. The total metabolic rate increases by at least 50 percent during late pregnancy. Compared to dry ewes, ewes in late pregnancy require about 50 percent more feed if bearing a single lamb and about 75 percent more feed if carrying twins. This amount of feed may exceed their intake capacity unless grain is substituted for part of the ration. It is likely that inadequate nutrition most commonly renders ewes susceptible to the disease, but many stresses can trigger pregnancy disease. Undernourished ewes may begin showing symptoms after they have been hauled or driven, during shearing, during short periods of fasting, during storms, during extreme cold or heat, or when they are excited by predators. Ketotic ewes normally lag behind the others when the flock is moving. The nutrient intake of ewes must be increased during the last three to four weeks of pregnancy. Grains are especially effective in providing a higher energy level. Ewes should not be allowed to become fat in early pregnancy, but they should be maintained in good condition. Avoid severely stressing ewes during the last three to four weeks of pregnanc Continue reading >>

Pregnancy Toxemia (ketosis) In Ewes And Does – 1.630

Pregnancy Toxemia (ketosis) In Ewes And Does – 1.630

by S. LeValley1 (8/2010) Quick Facts… Pregnancy toxemia in sheep and goats is also known as pregnancy disease, lambing sickness and twin-lamb/kid disease. The principal cause of pregnancy toxemia is low blood sugar (glucose). Onset of the disease is often triggered by one of several types of stress including nutritional or inclement weather. The disease is most prevalent in ewes and does carrying two or more lambs or kids. The disease also affects ewes and does that are extremely fat or excessively thin. The best preventive measure is increased feeding of high energy concentrates and grains during the last month of pregnancy. Occurrence and Causes Pregnancy toxemia in sheep and goats has also been called ketosis, lambing/kidding sickness, pregnancy disease and twin-lamb/kid disease. It occurs in all parts of the world and is an often fatal disease occurring only during the last month of pregnancy. Death occurs in two to 10 days in about 80 percent of the cases. It most often affects ewes/does pregnant with twins or triplets and is characterized by low blood sugar (glucose). Economic losses because of the disease have been considerable and it is the most commonly occurring metabolic disease of sheep and goats. It is generally accepted that the basic cause of pregnancy toxemia is a disturbance of carbohydrate or sugar metabolism. In earlier phases of the disease, blood glucose concentrations are less than 30 and may be as low as 10 mg/100 ml (normal 40-60). Blood ketone bodies, on the other hand, are usually greater than 15 and occasionally may be as high as 80 mg/100 ml (normal 1-4). The free fatty acid content of the blood plasma also is increased, meaning that body fat is being broken down and used for energy. Since glucose is essential for proper functioning of the Continue reading >>

Ketosis

Ketosis

Tweet Ketosis is a state the body may find itself in either as a result of raised blood glucose levels or as a part of low carb dieting. Low levels of ketosis is perfectly normal. However, high levels of ketosis in the short term can be serious and the long term effects of regular moderate ketosis are only partially known at the moment. What is ketosis? Ketosis is a state the body goes into if it needs to break down body fat for energy. The state is marked by raised levels of ketones in the blood which can be used by the body as fuel. Ketones which are not used for fuel are excreted out of the body via the kidneys and the urine. Is ketosis the same as ketoacidosis? There is often confusion as to the difference between ketosis and ketoacidosis. Ketosis is the state whereby the body is producing ketones. In ketosis, the level of ketones in the blood can be anything between normal to very high. Diabetic ketoacidosis, also known as DKA, only describes the state in which the level of ketones is either high or very high. In ketoacidosis, the amount of ketones in the blood is sufficient to turn the blood acidic, which is a dangerous medical state. When does ketosis occur? Ketosis will take place when the body needs energy and there is not sufficient glucose available for the body. This can typically happen when the body is lacking insulin and blood glucose levels become high. Other causes can be the result of being on a low carb diet. A low level of carbohydrate will lead to low levels of insulin, and therefore the body will produce ketones which do not rely on insulin to get into and fuel the body’s cells. A further cause of ketosis, less relevant to people with diabetes, is a result of excessive alcohol consumption. Is ketosis dangerous? The NHS describes ketosis as a pote Continue reading >>

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