Ketosis Nitric Oxide

The Ketogenic Keys To Optimal Health

If you or a loved one has been struggling with low energy, excess weight or a chronic or degenerative disease — or if you simply want to optimize your health and longevity — Mitochondrial Metabolic Therapy (MMT) can help Hay House is now offering my MMT online course, in which you will learn scientifically validated strategies to boost your mitochondrial function, which is foundational for good health and disease prevention Benefits of MMT include weight loss, reduced inflammation and lower cancer risk, increased muscle mass, improved insulin sensitivity, mental clarity and improved longevity By Dr. Mercola If you or a loved one has been struggling with low energy, excess weight or a chronic or degenerative disease like type 2 diabetes, Alzheimer's or cancer — or if you simply want to optimize your health and longevity — I have great news for you. In an earlier article, I announced that my book, "Fat for Fuel," would be complemented by an online course on Mitochondrial Metabolic Therapy (MMT) — a collaboration with nutritionist Miriam Kalamian, who specializes in nutritional ketosis. That course is now available, and for a limited time, you'll receive a $100 discount and over $200 in bonuses, plus free access to a future audio webinar that is currently being put together. I'm proud to say, there's really nothing else like it out there. The course consists of seven comprehensive lessons to teach you the keys to fighting chronic disease and optimizing your health and longevity. If you or someone you love has cancer, it will also augment any oncological treatment you might be undergoing. MMT is a whole new way of looking at nutrition, merging decades of my own research with the latest science on mitochondrial health, all of which has been peer-reviewed by more th Continue reading >>

When And How To Use Perfect Keto Perform Pre-workout

Most pre-workout powders are not ketogenic. You get a load of not-so-hidden carbs in one gulp of your regular workout drink mix. So many garbage ingredients like sucralose that spike glucose and set you back in your ketone production. Artificial flavors, binding agents, emulsifiers that cause GI distress and inflammation. And most don’t have ketones, which you absolutely need as an energy source while on a ketogenic diet. That’s where this new tool from Perfect Keto comes in, and this guide aims to help you make the most of Perfect Keto Perform Pre-workout: the only keto sports drink! What is Perfect Keto Perform Pre-workout? Every scoop of Keto Perform is a powerful mix of amino acids, MCTs, ketones and caffeine scientifically proven to give you a clean energy boost and help muscle growth, designed to fuel and support any type of workout while on the ketogenic diet. You need your mind and body working in sync. The ingredients of Keto Perform Pre-workout give you everything you need for performance. BHB for Energy and Mental Acuity One serving of Keto Perform Pre-workout gives you 7.7g of BHB. Beta-hydroxybutyrate is the first ketone body that kicks the metabolic state of ketosis into action. You get it from good fats like eggs, milk, cream, butter and ghee, and from exogenous ketones. BHB gets carried around in your blood and enters your cells, turning into acetoacetate (another ketone body), which in turn becomes acetoacetyl-CoA, which cleaves to acetone (another ketone body) and acetyl-CoA. Acetyl-CoA brings the ketones to the Krebs cycle, so you get adenosine 5’-triphosphate, or ATP, a.k.a the money! The energy coins of your cells. Therefore, BHB = ATP = energy. Most importantly, energy in the brain, too. BHB has an in with our brains. There’s no blood-brain Continue reading >>

What Happens When You Eat Nothing But Bacon For 30 Days Straight? [interview]

Meet Dan Quibell, the man behind The Bacon Experiment, a 30-day bacon fast (or feast…?). For 30 days straight, Dan consumed nothing but bacon, and the results will shock you! The Bacon Experiment came into my radar through a Facebook group focused on the ketogenic lifestyle. This was all around the time I had just got back on the keto wagon; the timing really couldn’t have been more perfect. While I found the experiment to be a bit extreme, I was intrigued and inspired by the determination displayed and the results achieved. I felt a genuine sense of camaraderie among the folks in his group. It’s a community of like-minded low carb folks that encourage and motivate each other. If you’ve got a Facebook, you’ve got to go check it out! And for those interested in conducting your own bacon experiment, you can download this free PDF walk-through and guidelines to ensure you are on the right track. Recently, I reached out to Dan for an interview to pick his brain about The Bacon Experiment and ketogenic living. He graciously agreed! Thank you so much for taking the time to answer my questions, Dan. Walk me through The Bacon Experiment step-by-step. What were your goals and expectations going into this? Dan: The Bacon Experiment was me eating nothing but bacon for an entire month. Two pounds of bacon, or roughly 30 pieces, every day. The goal here was to get people’s attention using BACON, then try to teach them something about low carb and ketogenic diets and all the benefits that come with it. Cutting out carbs has been life-changing for me, and I wanted others to benefit as well. I expected that even though I was eating 2500 calories a day, an increase of 500 calories a day for me, that I would not gain much weight, I already knew that eating fat and protein doe Continue reading >>

The Great Medical Disconnect

There is probably no greater disconnect in medicine than the root cause of obesity. Even if you think you already know the answer to this “obvious” question, it’s still worth reading on. The reason this question matters, of course, is clear to everyone. Obesity (and more broadly the syndrome we define as metabolic syndrome) predisposes us to virtually every disease afflicting us in the modern age. Above is a simple graphic from the journal Nature showing the linkage between obesity and all of its sequela. When you are obese, your risk of disease goes up. This is not disputed. Here is where the controversy starts…what actually makes us obese? Obesity is a disorder of fat accumulation – fat cells accumulate too much fat, relative to how much fat the body breaks down. Conventional wisdom, however, says obesity is a disorder of eating too much and/or exercising too little. These are not the same thing. Let’s turn to a well-respected source of medical information, Lehninger’s Principles of Biochemistry (the so-called “bible” of biochemistry). Go to the index and query, what makes fat cells fat? (the technical way of asking this question is, what causes adipose cells to accumulate triglycerides) and you’ll get the following response: “High blood glucose elicits the release of insulin, which speeds the uptake of glucose by tissues and favors the storage of fuels as glycogen and triacyglycerols, while inhibiting fatty acid mobilization in adipose tissue.” Let me translate this: Eating glucose (carbohydrates) increases insulin levels in our body. Insulin drives glucose into liver and muscle cells as glycogen (in small, finite amounts) and into fat cells as triglycerides (in unlimited amounts). Insulin also inhibits the breakdown and utilization of fat. Pa Continue reading >>

What To Expect From Ketogenic Diet?

Ketogenic diet is fast taking its place in the hall of fame of “clinically proven to be effective” diets. There are numerous health benefits of following a ketogenic lifestyle. Here we guide you about what to expect from ketogenic diet. The state of ketosis The ketogenic diet reduces the intake of carbohydrates, regarding it as the main source of body inflammation and other ailments causing inflammation in our bodies. By taking a diet high in proteins, you set yourself on the path to healthy weight loss along with numerous other benefits for you general well-being. Lose weight As we start to cut down on the carbs, our kidney drains out the potassium and sodium salts from our body. This reduces the amount of water content following a loss in weight due to this process. It should be noted that only strict adherence to this diet can bring out any long-term weight loss goals. Reducing Hyper Tension and High Blood Pressure A decrease in the amount of sugar intake during ketosis, reduces fructose content in our liver. This subsequently helps control the amount of nitric oxide and uric acid in our bodies. The increase of these products due to a high-carb diet narrows the blood vessels resulting in hypertension. When we reduce fructose by following a ketogenic diet, we can easily normalize our blood pressure. Increase HDL-The Good Cholesterol Commonly known as good cholesterol, HDL is actually the lipoproteins that carry cholesterol to the liver so that it can be excreted and not cause any damage to the body. A ketogenic diet consists of high-fat, low-carb foods. This high fat increases the HDL and thus reduces the chances of heart disease. Reduce Diabetes Ketogenic diet can actually help fight against diabetes. When someone suffers from insulin resistance, their bodies are Continue reading >>

Dom D’agostino — The Power Of The Ketogenic Diet

– Dominic D’Agostino Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. Many of you sent enthusiastic follow-up questions after the last conversation we had, so Dom took the time to answer your most popular questions. In particular, he focused on ketosis, ketones, and the ketogenic diet — so you can consider this a ketosis master class (especially if you combine both episodes, though this one does stand alone). It takes a few minutes for Dom to warm up — so be patient! If you have an interest in these types of metabolic therapies, whether for performance enhancement, endurance, weight loss, or fighting cancer, diabetes, or any number of other maladies, you will find a gem within this episode. If you only have 5 minutes, listen to Dom’s thoughts on how much protein you should eat on a ketogenic diet. Enjoy! Want to hear my first interview with Dom D’Agostino? — Listen to our in-depth conversation here. In this episode, we discuss fasting, heavy deadlifts, and the end of cancer (stream below or right-click here to download): This podcast is brought to you by Gymnastic Bodies. This is the training system that I am most obsessed with at the moment. Coach Sommer appeared on a previous episode of the podcast, which turned into a sleeper hit. He is the former USA national team coach for men’s gymnastics and creator of this bodyweight-based training system. I’m not easily impressed, and I have been completely blown away by the sophistication and the elega Continue reading >>

Keto Tip: Eat More Salt On A Ketogenic Diet!

I said last week that most issues with the Ketogenic Diet can be fixed by doing one of three things; drink more water, eat more salt, or eat more fat. Last week we talked about water, now let’s talk about salt. Of all the things that were difficult for me to start to do once I started eating on a Ketogenic diet, it was probably upping my salt intake that really messed with me the most. All my life I have had high blood pressure and of course, the first thing the Docs tell you to do is cut your salt intake. You may have heard of the DASH diet that consists primarily of veggies, lean protein, low fat dairy, fruits and whole grains and no added sodium. Well guess what that diet also happens to be low in? That’s right, our old friend sugar. And according to a 2010 University of Louisiana study, reducing your dietary sugar has a much bigger impact on your BP than added salt. Why is that? Here are 3 reasons. Hydrophilic Effects of Sugar One reason is that sugar is hydrophilic, in other words it tends to absorb water. So if you have high levels of blood sugar it will tend to absorb water creating a larger volume of fluid in your veins and arteries. This increased volume raises blood pressure. Insulin Resistance Blocks Magnesium Insulin helps your body store magnesium but if you are insulin resistant (and if you are obese, you are by definition insulin resistant) your cells wont take up the insulin or the magnesium that come along with it. Magnesium stored in cells relaxes your muscles and without it, the blood vessels become more rigid which increases blood pressure. On a personal note, once I started taking these Magnesium supplements I saw a huge drop in my overall BP as well as an easier time sleeping through the night. Fructose Elevates Uric Acid The metabolization of Continue reading >>

What Is The Ketogenic Diet And Is It Really That Gut Friendly?

The ketogenic diet or keto diet. There are claims that the ketogenic diet can help you lose weight and reduce your likelihood of developing diseases like diabetes and heart disease. So, what is the keto diet? I thought you'd never ask! Basically it's a very low-carb, high-fat way of eating that involves drastically reducing carbohydrate intake, and replacing it with fat. Once we starve our body of carbohydrates, our energy fuel source, we put our bodies into a metabolic state known as ketosis. Instead of using carbohydrates for energy, our bodies burn fat. Sounds great, right? Whilst the ketogenic diet can help with weight loss and reducing blood sugar, I like to look at the ketogenic diet with a pinch of salt (which is one thing that actually is allowed in the keto diet.) Once we demonise a whole food group, food no longer becomes our friend. Carbohydrates are not the enemy and everything, including carbohydrates, should be eaten and enjoyed in moderation! Not to mention that by cutting out carbohydrates, we lose out on the benefits of many nutrients that we need to support our gut function and immune system. In particular, we may miss out on very important prebiotics that are found in root vegetables, seeds, fruit and more. No, that was not a spelling error, I said prebiotics, not probiotics! We know that our microbiome is the community of bacteria that reside within our body and is responsible for more than just our digestive health. Within your gut, the healthy community of micro flora involves a greater number of probiotics or friendly bacteria, and a smaller amount of pathogenic bacteria. However our friendly, good guys need to be fed to maintain the survival of their colony. This is where prebiotics come in and in simple terms, they act as a food for probiotics. Continue reading >>

Top 5 Ingredients To Boost A Ketogenic Diet

The ketogenic diet is one of the most popular dietary trends for a successful weight loss. It can also be helpful in boosting your overall health, allowing you to avoid carbohydrate crashes while maintaining high energy levels. If you’ve been considering beginning a ketogenic diet, supplementation can play a key role in helping you achieve ketosis while avoiding the dreaded “keto flu.” Let’s take a look at the top 5 ingredients that can help you maximize the benefits of a ketogenic diet. MCT Powder The ketogenic diet is all about increasing your fat intake while eliminating most carbohydrates. Your protein consumption will be moderate. One of the best ways to push your body into a ketogenic state is with medium chain triglyceride powder. Medium chain triglycerides are fatty acids that promote ketosis. Aside from being helpful for the ketogenic diet, MCT powder may also boost weight loss and decrease your risk for cardiovascular disease. (1-2) HMB Next up is beta-hydroxy beta-methylbutyrate, more commonly known as HMB. This metabolite of the essential amino acid, Leucine, may not push your body into a state of ketosis; however, it is necessary to protect lean muscle tissue. When you make the dietary changes to dramatically lower carbohydrate stores, you need to ensure that your body is able to do so without jeopardizing muscle tissue. Too much dietary protein can be used to make glucose and this is what you want to avoid. The solution is HMB. HMB can help to trigger protein synthesis while protecting and promoting lean muscle tissue without the need for high levels of dietary protein. (3-4) Ready to make your own ketogenic booster? Now you can with the Amino Z Supplement Builder! Mix HMB and MCT Powder along with several other ketogenic ingredients for keto succe Continue reading >>

Arginine And Nitric Oxide Synthesis In The Pathogenesis Of Ketosis-prone Diabetes

Patients with KPD represent a unique subset of type 2 diabetes in which obese/overweight patients present with diabetic ketoacidosis despite absence of humoral or cellular ? cell autoimmunity, implying unique and profound ? cell dysfunction of unknown. In this project we propose to test the general hypothesis that the severe but partially reversible and intermittent ? cell dysfunction in KPD is mediated through diminished availability of arginine for NO synthesis, which in turn impairs insulin secretion. Specific hypotheses to be tested are: 1. Compared to healthy subjects and """"""""usual"""""""", non-ketosis-prone T2D patients, KPD patients have decreased intracellular arginine availability due to a) increased arginine catabolism caused by elevated plasma arginase activity, and b) decreased arginine synthesis due to diminished citrulline synthesis and efflux from the intestine. 2. Due to diminished arginine availability, KPD patients have impaired glucose-stimulated insulin secretion, as well as impaired endothelial function;however the insulin response to arginine + glucose is normal. 3. Enhancement of intracellular arginine availability will result in improved glucose-stimulated insulin secretion in KPD patients. However, due to increased arginine catabolism by arginase, this can be achieved more effectively by dietary citrulline supplementation than by dietary arginine supplementation. Using stable isotope tracer methods these hypotheses will be tested in groups of KPD patients, type 2 diabetics and healthy controls by achieving the following aims: Aim 1 a. Measure under basal conditions and following a hyperglycemic clamp, a) arginine flux, de novo synthesis from citrulline, release from protein breakdown, rate of conversion to ornithine and to NO;b) ornithine an Continue reading >>

Benefits Of Keto Diet And Therapeutic Ketosis For Body Oxygen Levels

Module 11-6. Nutrients and diet for better body oxygenation The ketogenic diet (definition) is a high-fat, low-carb, moderate-protein diet that is used with the purpose to use fats as the main energy source due to the metablic state called "ketosis". This diet relates to LCHF (low-carohydrate high-fat) diets. Keto-adaptation (definition) is a transitional period that allows the body to metabolically adapt to using fats as the main fuel for the brain, heart and other tissues of the body. It usually lasts about 2-4 weeks. Keto-adaptation can be reduced to less than 1-2 days for people with 60+ s MCP and is probably present naturally for those who have 90+ s CP 24/7. Ketosis (definition) is a metabolic state where body cells use energy supply that comes mainly from ketone bodies in the blood rather than blood glucose. Ketosis and reliance on fats as the main energy source had been the most common physiological metabolic features during evolution of human beings. Dramatic increase in consumption of grains became possible due to evolvement of agriculture to its modern aggressive forms. Who will benefit from ketosis: overweight, type 1 and 2 diabetes, cancer, leukemia, heart disease, any neurological disorder (including epilepsy, Parkinson, Alzheimer, MS or multiple sclerosis, senile dementia, schizophrenia, and depression), any digestive disorder (including IBD or Crohn's disease and ulcerative colitis, gastritis, IBS, liver cirrhosis, and hepatitis), any respiratory problem (asthma, bronchitis, COPD, emphysema, etc.) and any other inflammatory condition - or about 90% of overall population. If we measure the total amount of glucose in human blood, it would be about 5-10 g or only 1-2 teaspoons. When eating an ordinary meal, a person often consumes 10-30 times more carbs tha Continue reading >>

Increased Nitric Oxide Caused By The Ketogenic Diet Reduces The Onset Time Of Kainic Acid-induced Seizures In Icr Mice.

Abstract Although the antiepileptic effects of the ketogenic diet (KD) are well documented, the mechanisms underlying this action remain obscure. Nitric oxide (NO) has long been thought to play a role in regulating seizures. However, the effects of the KD on endogenous NO production have not been characterized. Therefore, the present study was designed to examine the effect of the KD on endogenous NO production, as well as the precise role of NO in kainic acid (KA)-induced seizures, in male ICR mice. We first found that preadministration of the KD for 4 weeks increased endogenous NO generation in the hippocampus. We also demonstrated that the increase in NO induced by the KD resulted from increased neuronal NO synthase (nNOS) activity and exerted an antiepileptic effect on KA-induced seizures, based on the results of experiments using NOS-knockout mice and two NOS inhibitors, N-omega-nitro-L-arginine methyl ester (L-NAME) and 7-nitroindazole (7-NI). These data suggest that the antiepileptic effects of the KD might be mediated, at least in part, by increased NO levels in the hippocampus. Continue reading >>

Ketogenic Diet Lowers Blood Pressure: Fat For Fuel!!

Low Carb – High Fat Diets It wasn’t that long ago that low-carb diets were being targeted by medical professionals as unhealthy and detrimental to people’s health. The high fat intake in these diets was thought to be at the root of increased cholesterol and subsequent heart disease. However, in the last 15 years or so, due to a significant number of studies, the medical field has started to change its tune. Now it seems that low carb diets are seen to be amongst the most effective in dealing with a number of health conditions, including high blood pressure, high cholesterol, weight loss and circulatory and other metabolic diseases. The Ketogenic Diet – what exactly is it? According to Dr Joseph Mercola, a highly respected Osteo-pathic physician and Alternative Health Advocate, the Ketogenic Diet is “An eating plan that’s low in sugar and net carbs (carbs without fiber), moderate in protein and high in healthy fats. A ketogenic diet helps you reach nutritional ketosis where your body burns fat for its primary fuel instead of cell-damaging carbs.” The body is designed to use fats more efficiently than carbohydrates with the result that by eating more healthy fats, less protein and carbs you will kick start the body’s metabolism to burn more fat and ketones. Ketones are substances which naturally occur in the body and are created in the liver. These are then the substances which are purposed to be turned into and used as energy. Additionally, this ketogenic process will also stimulate the mitochondria (the fuel producing elements of each cell) to produce optimal amounts of energy. This is certainly very beneficial to the body as a whole, and especially to the high energy-driven organs like the brain, heart and muscles. for more info click here How does this Continue reading >>

Why Be In Ketosis? Headaches, Bp, Nitrous Oxide

Click on Bacon Boy to get a printable PDF and then take your most creative selfie with him. Then share your art on Facebook, Instagram or Twitter and include: Continue reading >>

The Top Twelve (dirty Dozen) Potential Dangers Of A Low Carb Diet:

Low Carb (or Ketogenic) Diets are incredibly popular right now here in the U.S. and I see men on that diet all the time on Peak Testosterone Forum. Altthough, Low Carb Diets have been around for decades with various names and in various forms, they have recently flourished as never before due to the fact that a significant number of doctors and researchers have become apostles of the movement. Weight loss is rapid, due to loss of water attached to glycogen stores, and lipids usually improve in some positive ways, such as rising HDL and falling triglycerides. If you're a meat and dairy lover, this diet seems like a dream-come-true. But behind the scenes, ugly side effects and research have been surfacing and literally tens of millions have jumped aboard. I see over and over men that show up on The Forum with standard symptoms that they assume are testosterone or estradiol related. In fact, I find that they are likely experiencing one or more of the common side effects of Low Carb Diets. Some men even get incredibly ill, and I did an interview with one of them here: A Low Carb Diet Made Me Sick. To be clear, I am NOT saying that all of these side effects occur in all men on a Low Carb Diet. I am just saying that they occur often enough that men should be aware and monitoring themselves. Plus, many men on a Low Carb Diet are feeling terrible and do not know why. For all these reasons, I urge you to read for yourselves 1. Heart Palpitations and Arrhythmias. Perhaps the most dangerous aspect of a low carb diet are the ketones. What?!? That's not what you heard, right? Low carb bloggers love to go on and on about the benefits of ketones - and there are some - but there is also a dark side. (Low carb diets are labelled ketogenic, becausse ketone levels in the blood are elevate Continue reading >>