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Ketosis In Other Animals

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Dear Mark: Ketosis

Dear Mark, What are ketones? How does ketosis play into the Primal Blueprint? Did our bodies evolve to run on ketones? If not, why do they exist? Ketones, to put it briefly, are compounds created by the body when it burns fat stores for energy. When you consume a diet very low in carbohydrates, the body responds to the significantly lowered levels of blood sugar by flipping the switch to another power source. The body converts fatty acids in the liver to ketones. Ketones, then, become the main energy source as long as blood sugar levels remain low. Recently, researchers have discovered more about the unique mechanisms behind this energy “switch.” It turns out a specific liver hormone, FGF21, is essential for the oxidation of the liver’s fatty acids. Furthermore, animals who were fed a ketogenic diet over time showed “increased expression of genes in fatty acid oxidation pathways and reduction in lipid synthesis pathways.” In other words, their bodies adapted metabolically and genetically to the diet. Ketosis was crucial to our evolution. Given the relatively minor role of carbohydrate-rich foods (even the consumption of many tubers is thought to have come later with the a Continue reading >>

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  1. Carb-FreeNation

    Looking for some details and understanding about the metabolic states of carnivorous animals. Are, say, lions in a ketogenic state their entire lives? Is that a meaningful question, or is something completely different going on? +1 internet points if you can point me in the direction of good info.

  2. erixsparhawk

    Article about ketosis in the animal kingdom. http://caloriesproper.com/ketosis-in-an-evolutionary-context/
    Bears don't go into ketosis. Hypercarnivores will go into ketosis only when they are starving but not on low carb diets.

  3. simsalabimbam

    It is not a very meaningful question.
    Humans are evolutionary adapted towards ketosis, we leverage the advantage of being able to survive mainly on ketones, formed during the liberation of stored energy (body fat).
    No other animals have adapted to support such a large brain / body mass size.

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We perform the experiment in the animal house facility of our university.

Effect Of The Ketogenic Diet On The Activity Level Of Wistar Rats

Children, adolescents, and adults with epilepsy often also show symptoms associated with attention-deficit/hyperactivity disorder (ADHD). The ketogenic diet, which is administered to children with epilepsy refractory to drug therapy, seems to improve behavior in individuals with symptoms of ADHD. The basis for this improvement is unknown, although it seems to be unrelated to seizure control. The present research was designed to investigate the effect of two ketogenic diets on the behavior of normal adult male rats. Two experiments were conducted. In experiment 1, 36 subjects were placed on one of three diets: a control diet, a 6.3:1 ketogenic diet, and a 4:1 ketogenic diet. In experiment 2, 20 subjects were placed either on a control diet or on a 4:1 ketogenic diet. The activity level of each subject was measured using an open field test. Time spent immobile, grooming, and in exploratory behavior was measured for 600 s. Subjects were tested once before initiation of the diets and once while on the diets. No significant group differences were found in activity level before initiation of the diets. After initiation of the diets, subjects in both ketogenic groups showed a significantl Continue reading >>

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  1. edmon171

    Does anyone know about the metabolic state of of other hunting carnivores such as wolves, lions, etc.? Do they stay in ketosis all the time? I know their pattern is to hunt, eat a ton of fat and protein, then rest and fast for several days before hunting again. I imagine they get away with the fasting and maintain their weight by gorging on so much protein that it converts to blood sugar and they can restore the fat they lost. Does this take them out of ketosis and they need to then re-adapt every week? Do they also consume the fermented stomach contents of the kill? Is it the lucky alpha who gets the liver first who is best able to maintain their weight?

  2. kayaman

    No. They do not state on ketosis all the time. it depends on what kind of animal. From the land strict carnivores as cats cats they eat large amounts of protein (50-60% of calories in the diet) and their liver efficiently, quickly and without problem (as opposed to human) is cleaved protein to glucose. They do not eat fatty. Often, big cats leave part of organs, bone marrow and fat for scavengers such as hyenas. Dogs are already really omnivores and effectively operate on 40% protein and 60% fat in calories.
    I do not know the proportion of other predators such as sperm whales and seals.
    It seems to me that the cow is on ketosis much more than cats. In her share of the energy of carbohydrates is very small as long feed on naturally of course.

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Veterinarian outlining the causes and symptoms of ketosis in dairy cattle, and demonstrating treatment using Bayer metabolic solutions. Filmed on farm in New Zealand.

Ketosis (acetonaemia)

General information Ketosis in cattle is associated with an inadequate supply of the nutrients necessary for the normal carbohydrate and fat metabolism that is seen mainly in times of high milk production in early lactation. The excessive ketone bodies in the bloodstream come from the breakdown of fat when the animal is forced to draw on its bodily reserves for energy. Although the metabolism of body fat provides energy for cows, the nervous system is dependent on glucose, and the ketones produced as a result of excessive fat metabolism can have toxic effects. The excess ketone bodies are eliminated in the urine, milk and breath of the animal. Overview Cause Ketosis may develop from poor diet or periods of stress such as cold, wet weather. It may also affect apparently well-fed cows producing very large volumes of milk. In pasture-fed cows the condition is usually seen when the grass is drying off and green feed is scarce. The disease is relatively common in lactating cows in Australia but often goes unnoticed in its mild forms. The mortality rate in affected cattle is low and spontaneous recoveries occur in many cases. The disease is usually seen in early lactation (within the fir Continue reading >>

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Popular Questions

  1. Carb-FreeNation

    Looking for some details and understanding about the metabolic states of carnivorous animals. Are, say, lions in a ketogenic state their entire lives? Is that a meaningful question, or is something completely different going on? +1 internet points if you can point me in the direction of good info.

  2. erixsparhawk

    Article about ketosis in the animal kingdom. http://caloriesproper.com/ketosis-in-an-evolutionary-context/
    Bears don't go into ketosis. Hypercarnivores will go into ketosis only when they are starving but not on low carb diets.

  3. simsalabimbam

    It is not a very meaningful question.
    Humans are evolutionary adapted towards ketosis, we leverage the advantage of being able to survive mainly on ketones, formed during the liberation of stored energy (body fat).
    No other animals have adapted to support such a large brain / body mass size.

  4. -> Continue reading
read more

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