
Paleo Diet Problems
It’s time to tell you what I know and you may not want to hear. Unlike many or most other diet advocates, we don’t hide from problems around here. We self-experiment, use evolutionarily-backed reason and principles, form reasonable hypotheses, experiment more, figure it out, and fix it. We’re animals, and there will be a way, for everyone. Don’t be surprised, but not everyone reports all systems normal — or even great — on the Paleo-like diet long term; which, generally, is the elimination of grains, sugar, processed food, vegetable oils (eat meat, fish, fowl, natural fats in abundance, veggies, some fruit, some nuts). Some include dairy to tolerance and some — including myself — don’t worry about starch so much, now that I’m at a normal weight and body composition. But most — including myself — still stay low to moderate carb. I probably average less than 100g per day, but that would be an average. Having the blog I do, I get lots of comments and lots of emails. Here’s a quick summary of the problems I’ve seen reported, and I’m generally going to go from most common to least, based on my general impression. Diarrhea. This is a big one, and one I’ve suffered from, time to time and rather inexplicably. Hypothyroidism. I was hypothyroid and on synthetic T4 for years before, even as I was gaining weight. When I rapidly began to lose and realized I didn’t need the GERD or allergy meds anymore, I willy-nilly dumped the T meds as well. Then I tested 16 on TSH (you want about 1 or less). I stuck with the plan and TSH actually improved, but only to 11. Then I went on natural T, i.e., Armor (which includes T3, because sometimes the problem is an inability to convert from the inactive T4 to active T3). Now my numbers are pretty normal. But for ot Continue reading >>

‘strange Pain’ In Side Related To Low-carb?
A reader e-mailed me yesterday about something that reminded me of something my wife Christine has been going through this year. You might remember me talking about Christine having a mysterious pain in her side that was causing her a lot of pain and test after test after test kept coming back negative. Finally, she saw a surgeon about it last month and he determined it was her gall bladder. It was removed a few weeks ago and Christine is now feeling a million times better. So when I read about this very active 26-year-old, 115-pound woman having “a strange pain appear on my lower right abdominal side,” I immediately perked up. However, unlike Christine who is NOT livin’ la vida low-carb, this woman has been on a low-carb diet for health reasons since April 2006 and was seeing fantastic improvements in her health and skin. But then that “strange pain” hit her with a nearly constant feeling that felt like she was “stabbed inside, swollen, crampy.” It has come and gone several times, but has gotten progressively worse and worse with no signs of improvement. She has gotten tested with x-rays, an ultrasound of various regions of her abdomen, blood tests and everything has come back normal. In fact, since she started livin’ la vida low-carb, her lipid profile has been excellent and she has not had any problems with indigestion or acid reflux. One area of her health that has change is her period cycle which she said has been “messed up” since all of this started. “I bleed between periods for a day or two, and also the first period after I began with my low-carb diet was missing (or was at least very delayed),” she wrote. There are a lot of things this could be and I wrote back to her stating I am by no means an expert on these kinds of conditions, espe Continue reading >>

Effects Of A Low Carbohydrate Diet: Overview
No matter what Atkins or other diet books tell you, the balance of evidence clearly shows that saturated animal fat is bad for you and is associated with increased risk of cancer [Journal of the National Cancer Institute 95 (2003): p.1079], diabetes, and heart disease. [WHO Technical Report Series 916, 2003] Even independent of the effects on obesity, meat consumption itself has been related to increased risk of coronary heart disease [Preventive Medicine 13 (1984): p.490] and for over 40 years medical reviews have also shown the detrimental impact of dietary cholesterol consumption. [Geriatrics (1961): p.407] The Chair of the American Medical Association's Council on Food and Nutrition explained in testimony before Congress why the AMA felt they had to formally publish an official condemnation of the Atkins Diet: "It became apparent that the (Atkins) diet as recommended poses a serious threat to health." "People need to wake up to the reality," Former U.S. Surgeon General C. Everett Koop writes, that the Atkins Diet is "unhealthy and can be dangerous." [Shape Up America! news release, 29 December 2003] The largest organization of food and nutrition professionals in the world calls the Atkins Diet "a nightmare of a diet." [Journal of the American Dietetic Association 102 (2002): p.260] The official spokesperson elaborated: "The Atkins Diet and its ilk – any eating regimen that encourages gorging on bacon, cream and butter while shunning apples, all in the name of weight loss – are a dietitian's nightmare." The ADA has been warning Americans about the potential hazards of the Atkins Diet for almost 30 years now. [Journal of the American Dietetic Association 66 (1975): p.277] The National Academy of Sciences, the most prestigious scientific body in the United States, Continue reading >>
- The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus
- The interpretation and effect of a low-carbohydrate diet in the management of type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials
- Pre-diabetes goes into remission on higher protein, lower carbohydrate diet (Zone diet balance)

Review The Challenge Of Intra-abdominal Sepsis
Abstract An overview of intra-abdominal sepsis is necessary at this time with new experimental studies, scoring systems and audits on management outcomes. The understanding of the pathophysiology of the peritoneum in the manifestation of surgical sepsis and the knowledge of the source of pathogenic organisms which reach the peritoneal cavity are crucial in the prevention of intra-abdominal infection. Inter-individual variation in the pattern of mediator release and of end-organ responsiveness may play a significant role in determining the initial physiological response to major sepsis and this in turn may be a key determinant of outcome. The ability to identify the presence of peritoneal inflammation probably has the greatest influence on the final surgical decision. The prevention of the progression of sepsis is by early goal-directed therapy and source control. Recent advances in interventional techniques for peritonitis have significantly reduced the morbidity and mortality of physiologically severe complicated abdominal infection. In the critically ill patients there is some evidence that the prevention of gut mucosal acidosis improves outcome. The aim of this review is to ascertain why intra-abdominal sepsis remains a major clinical challenge and how a better understanding of the pathophysiology may enable its prevention and better management. Electronic searches of the medline (PubMed) database, Cochrane library, and science citation index were performed to identify original published studies on intra-abdominal sepsis and the current management. Relevant articles were searched from relevant chapters in specialized texts and all included. Continue reading >>

Blood And Protein In Urine Appendicitis
Blood And Protein In Urine Appendicitis - Protein supplements affect liver blood tests, Protein is an essential nutrient needed to build muscle, repair and maintain connective tissue, and synthesize enzymes. most americans are not protein. Causes diagnosis hematuria (blood urine), Blood in the urine (referred to as hematuria) can have many causes ranging from simple to serious which your doctor can pinpoint with certain tests.. Know kidney numbers: simple tests - national, Did you know one in three american adults is at risk for kidney disease? anyone can get kidney disease at any time. if kidney disease is found and treated early, you. Alt | canine liver disease foundation, A thorough approach is needed for a correct diagnosis of any liver problem. an organ like the liver that is so intimately involved with other important organs will. Liver disease symptoms - symptoms liver problems, Liver disease symptoms. often people feel that they might be suffering from some kind of liver disease but it can be a hideous act for anybody to identify. Liver function tests & blood tests - university north, Written by jens joergen jaeger and hanne hedegaard, denmark. about blood tests . what does it mean - and what is normal in blood tests ? the names may be different in. How kidneys work - national kidney foundation, Removing waste from the body is only one of the main functions of your kidneys. take a look at the things kidneys do that makes them so important.. Liver panel - lab tests online, A blood sample drawn from a vein in your arm; for infants, blood may be drawn by puncturing the heel with a lancet.. Natural home remedies kidney stones pain: treatment, Kidney stones are hard masses in the kidneys and bladder and are made up of tiny minerals that crystallize in the kidneys. re Continue reading >>

Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus.[1] Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness.[1] A person's breath may develop a specific smell.[1] Onset of symptoms is usually rapid.[1] In some cases people may not realize they previously had diabetes.[1] DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances.[1] Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids.[1] DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies.[3] DKA is typically diagnosed when testing finds high blood sugar, low blood pH, and ketoacids in either the blood or urine.[1] The primary treatment of DKA is with intravenous fluids and insulin.[1] Depending on the severity, insulin may be given intravenously or by injection under the skin.[3] Usually potassium is also needed to prevent the development of low blood potassium.[1] Throughout treatment blood sugar and potassium levels should be regularly checked.[1] Antibiotics may be required in those with an underlying infection.[6] In those with severely low blood pH, sodium bicarbonate may be given; however, its use is of unclear benefit and typically not recommended.[1][6] Rates of DKA vary around the world.[5] In the United Kingdom, about 4% of people with type 1 diabetes develop DKA each year, while in Malaysia the condition affects about 25% a year.[1][5] DKA was first described in 1886 and, until the introduction of insulin therapy in the 1920s, it was almost univ Continue reading >>

Analysis Of Health Problems Associated With High-protein, High-fat, Carbohydrate-restricted Diets Reported Via An Online Registry
A Report by the Physicians Committee for Responsible Medicine While a few recent studies have noted that high-protein, carbohydrate-restricted diets facilitate modest short-term weight loss,1-3 no studies to date have investigated the long-term health consequences of consuming such diets for weight-loss purposes. Studies of general populations consuming diets high in fat, particularly saturated fat (low-carbohydrate diets have not been studied specifically) have shown increased risk of cancer,4-6 diabetes,7 and heart disease.7 Mixed diets high in animal protein have been shown to increase the risk of kidney problems,8,9 osteoporosis,10,11 and some types of cancer.12,13 These studies raise concerns as to whether low-carbohydrate diets, which are typically high in saturated fat and animal protein, might pose the same risks. In addition, because fiber is found only in plant foods, and high-protein, high-fat, carbohydrate-restricted diets tend to be low in plant foods, these diets are also typically low in fiber. In studies of general populations, low fiber intake is associated with increased risk of colon cancer and other malignancies,4 heart disease,7 diabetes,14,15 and constipation.16 Again, these studies raise the question as to whether similar problems occur in low-carbohydrate dieters. Some high-protein, very-low-carbohydrate, weight-loss diets are designed to induce ketosis. When carbohydrate intake or utilization is insufficient to provide glucose to the cells that rely on it as an energy source, ketone bodies are formed from fatty acids. An increase in circulating ketones can disturb the body’s acid-base balance, causing metabolic acidosis. Evidence suggests that even mild acidosis can have potentially deleterious consequences over the long run, including low blo Continue reading >>

Fatty Liver And Its Treatment.
Fatty liver (steatosis) is pretty much the precondition of fibrosis, cirrhosis and hepatocellular cancer.Steatosis and hepatic IR are closely associated but it is still poorly understood whether it is steatosis which causes IR, or vice versa. It is clear however that steatosis and IR usually precede inflammation, fibrosis, and cirrhosis of the liver. Steatosis is produced experimentally in animals by a) toxins and alcohol – in which case the effect will be made worse by high-PUFA diets, reversed by diets providing highly saturated fats, usually beef tallow or coconut oil, and kept stable by moderately saturated fats such as olive oil and lard, b) high-fat diets (high PUFA) with round-the-clock feeding (but not with feeding in a time-restricted window), c) diets deficient in choline, or in the raw materials needed to make choline; methionine, folate and B12 (however, deficiencies of B12 and folate have other serious effects which might mask their importance in this regard), d) diets deficient in antioxidants that prevent lipid peroxidation, usually selenium and tocopherol. Up-regulation of PPAR-alpha is protective against steatohepatitis and inhibits HCV replication. PPARα was also reported to be down-regulated by HCV in the liver of infected patients [88, 89]. Since PPARα blocks the replication and production of infectious viral particles, its downregulation likely confers a replicative advantage to the virus in spite of the resulting metabolic disorders for the host cells [90, 91]. PPAR-alpha is upregulated by intracellular peroxidation of DHA, by carbohydrate restriction, and by fasting, as well as by the flavanone naringenin, an antioxidant found in grapefruit, oranges and tomatoes. From this we might be able to construct a diet that prevents or reverses fatty li Continue reading >>

Gallbladder Disease And The Standard American Diet – My Personal Account
Do you suffer from gallbladder pain or gallstones? Many doctors suggest eating a so-called “low-fat” diet, taking drugs, and if trouble persists, having the gallbladder removed (cholecystectomy). The biggest problem with this advise is that doctors will tell patients that something is actually wrong with the organ itself – that it’s malfunctioning, and needs to be removed. That’s only part of the story. Most of the time, they completely fail to mention the cause of gallbladder disease in the first place. Patients are told the terrible news – that gallstones usually cannot be avoided. The other organ doctors are fond of harvesting, which we are told we can do without, is the appendix. Again, no one mentions to patients why their appendix is failing. Although you might be told that for some unknown reason, the appendix becomes clogged with toxins over time – and there is nothing you can do about it. But actually, this is not the case. The purpose of the gallbladder and appendix Like the appendix, which has finally been acknowledged recently by modern medicine to actually “having a function” in supporting the endocrine and immune systems, the gallbladder has long been thought to be an organ we can live without. The appendix is actually critical in the storage of beneficial bacteria which support digestion and immune system health. If you’ve had your appendix removed, you will need to eat fermented and cultured foods regularly to maintain this proper balance of good flora to support every aspect of your health. Research shows that removal of this important organ can actually lead to health issues including diarrhea from constant bile dripping into the small intestine which can lead to colon and bowel cancer. Losing an organ like the gallbladder causes th Continue reading >>
- American Diabetes Association® Releases 2018 Standards of Medical Care in Diabetes, with Notable New Recommendations for People with Cardiovascular Disease and Diabetes
- Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial
- Surgery for weight loss: A standard treatment for type 2 diabetes?

Plexus Slim Dangers – “do You Know How Dangerous The Pink Drink Is?”
Generally, many people are accustomed to following dietary programs, doing plenty of exercises, and body workouts to lose weight. However, for obese people, the two methods alone are not enough to suffice significant weight loss. Such people not only need to intensify their weight loss plans, but also need other additional weight loss techniques such as the use of weight loss supplements. As a result, people combine several product to lose weight. For instance, such people will combine diet pills, body workouts, and following strict dietary programs to lose weight and keep in shape. What people fail to understand is the fact that the diet pills they are used to are not manufactured under the same conditions nor are they made using the same ingredients. Some of them are more harmful and cause adverse health risks when used. Why market research before buying Plexus Slim is necessary Intuitively, people look for quality and ability to work effectively in slimming pills. Therefore, when searching for the best slimming pills to buy, it is always wise to carry out a comprehensive market research on different slimming pills available before settling for one. Advisably, ask friends who have experience using some of the slimming pills, but if you cannot find one, search for online customer reviews and blogs, as they can help you learn some of the important facts about the different products before making a choice. You must always keep in mind that choices have consequences, and if you make a wrong choice, the consequences can even be worse than you can imagine. Plexus slim is a pure natural weight lose supplement that is solely made from natural ingredients. Meaning, if there must be any plexus slim dangers, then they must be minimal, as the product does not come with any harmfu Continue reading >>

Strange And Schafermeyer's Pediatric Emergency Medicine, 4e >
Abdominal pain accounts for approximately 10% visits and elicits a broad differential, with more serious etiologies often presenting similar to processes that are benign and self-limited.1 The most frequently encountered surgical and medical causes of abdominal pain are addressed herein, including causes of abdominal pain that are unique to the female and male reproductive tracts. Abdominal pain can be visceral or somatic. Visceral pain is poorly localized and difficult to describe, even in older children; somatic pain is intense and readily localized. Referred pain syndromes manifested as abdominal pain may be characteristic of a variety of clinical problems. An effective relationship with the caregiver and careful observation can provide abundant information about a child's diagnosis. With older patients, the presence of a caregiver may hinder communication, particularly when needing an accurate sexual history. Overall, formulate questions appropriate for the child's level of development, regardless of the patient's age. Use open-ended inquiries over “yes or no” questions. Create a preliminary differential diagnosis, including abdominal conditions, systemic illnesses, and referred pain syndromes. Afferent nerves from distant organs can share central pathways that allow pain from one organ to be interpreted as if the stimulus is affecting another organ. A classic example is a right lower-lobe pneumonia that refers pain to the abdomen mimicking appendicitis. Conversely, some conditions that are intra-abdominal in origin may produce pain syndromes that are manifested in other locations; for example, shoulder pain due to hepatic irritation (right), or splenic rupture (left), and groin pain from renal stones. Table 69-1 lists extra-abdominal and systemic conditions tha Continue reading >>

4 Steps To Heal Diverticulitis Naturally
Is it possible to heal diverticulitis naturally? Let’s say a routine colonoscopy has confirmed that the abdominal complications you have been experiencing is a consequence of diverticulitis. You have been prescribed antibiotics as the recommended conventional treatment for the disease but is this approach in your best interest? Antibiotic treatment has its own risks and can cause pain within the first few days of treatment in which patients are then usually prescribed narcotics. So what should you do? Ignoring signs of the failing health of your digestive tract can lead to worsening symptoms, weakened immunity, and the possibility of interventions like unnecessary surgery in the future. Fortunately, there are natural and inexpensive ways you can treat the infection residing in your digestive tract and prevent flare ups from occurring. In this article, you will discover 4 steps to heal diverticulitis naturally. What Causes Diverticulitis? Small, tubular shaped bulging sacs along the gastrointestinal tract increase in prevalence with age affecting 70% of individuals before they reach 80 years old (13). These pouches are called diverticula and usually concentrate along the colon. Inflammation of one diverticulum or several diverticula can be triggered by a hard mass of feces causing bacteria overgrowth and a resulting infection known as diverticulitis. (1) Various influences contribute to impacted diverticula and infection. One of the greatest factors believed to affect incidence rates is diet. Today our bodies are burdened with managing poor dietary habits in a culture consumed by processed goods, sugar, and trans-fats. Our busy lifestyle has us neglecting the healthy lifestyle choices we should be making. As a consequence we deny ourselves sufficient time to exercise, Continue reading >>

Is Ketosis Dangerous?
Duck Dodgers October 14, 2014 Peter, An article by Per Wikholm was published in this month’s LCHF Magasinet, where Per demonstrates that the Inuit could not have been in ketosis given that the scientific literature is abundantly clear, over and over again, that the Inuit consumed too much protein, and more importantly, Per debunks Stefansson’s claims for high fat with writing from his own books—Stef admitted in the pemmican recipes that Arctic caribou was too lean to make pemmican that supported ketosis. The most popular LCHF bloggers in Sweden, Andreas Eenfeldt/Diet Doctor and Annika Dahlquist have reluctantly agreed with Per’s findings—admitting that the Inuit were likely not ketogenic from their diet. I’ve put together a comprehensive review of the scientific literature regarding the Inuit, encompassing over two dozen studies, spanning 150 years, with references from explorers, including Stefansson. In the comments section of that post, Per gives a brief overview of how he was able to prove Stefansson’s observations on high fat intake were flawed. The post is a review of all the available literature that I could find (over two dozen studies). But, the literature certainly does not in any way support ketosis from the Inuit diet due to such high protein consumption. As Per (and Stefansson) points out, the caribou is too lean and as the many quotes show, the Inuit were saving their blubber and fat for the long dark Winter to power their oil lamps and heat their igloos. Again and again, we see that in the literature, as even Stefansson admits this. As far as glycogen is concerned, their glycogen intake is probably not worth scrutinizing given the well-documented high protein consumption in every published study. It really is besides the point. But, interest Continue reading >>

Appendicitis Diet: Can Foods Lead To This Disorder?
Since appendicitis occurs in a part of the digestive system, it’s not unusual for people to blame their diet for this ailment Although many doctors tell their patients that they can eat “anything,” remember that there are certain foods that you should limit or avoid during the first month after having an appendectomy When it comes to this condition, one question that most people would usually ask is "What foods can actually cause appendicitis?" Since this disorder occurs in a part of the digestive system, it's not unusual for people to blame their diet for this ailment. But while it's true that what you consume has a direct impact on your digestive (and overall) health, it does not necessarily mean that the foods you eat can actually cause this disorder. Spicy Foods and Plant Seeds Are Often (Wrongly) Blamed for Appendicitis People who love spicy foods often feel disheartened when they're told that these can cause appendicitis. But the truth is that eating spicy foods cannot cause appendicitis and will not make it burst. While it's possible for a piece of spicy food to cause a blockage in the appendix, it is not the spiciness of the food that can lead to this condition. However, consuming spicy foods like hot peppers, chili and salsa can affect your digestion, cause discomfort and mimic the early signs of appendicitis. It can lead to indigestion, which causes severe pain in the area between the breastbone and bellybutton (the area of the body where appendicitis first manifests), as well as nausea. Sometimes, the pain is so severe that it's often mistaken for appendicitis or a burst appendix — even though it's not.1 Fruit and plant seeds and other residuals are also sometimes blamed for appendicitis, and for this reason, people become hesitant to consume them. Ex Continue reading >>

What Does Ketosis Mean?
Ketosis does not mean that you are losing weight. It really just means that your liver is turning a lot of protein and other noncarbohydrates to sugar. Today, many people on the Internet are urging people to eat a ketogenic diet: a diet that is so high in fat and so low in carbohydrates that it causes people to go into a state of ketosis. Ketosis means that “ketone bodies,” which are the chemical byproducts of an alternative method of burning fat, build up in the bloodstream. Ketogenic diets are often described as “Paleo” because many laymen imagine that human beings must have eaten ketogenic diets during the Paleolithic era (early stone age). Yet there is no reason to believe that stone age people ate a ketogenic diet. Most people in the stone age would have eaten the starchy plant material, especially roots and tubers, that they could safely and easily obtain from their environment. As a result, stone age people would have gotten more than enough carbohydrate to keep them from going into ketosis. In fact, when anthropologists look at the skeletal remains of stone age people, they find starch grains embedded in the tartar on their teeth. Even the Inuit’s (Eskimos’) traditional winter diet, which consisted entirely of fatty meats and fish, did not produce ketosis. Studies done in the early 20th century found that the Inuit did not get ketosis unless they were fasting. The Inuit were eating raw meat that was either freshly killed or frozen immediately after being killed. Unlike the meat you would buy at a supermarket, this fresh or rapidly frozen meat still contained a starch called glycogen. The Inuit also used a method of meat preservation that converted some protein to sugar. As a result, the Inuit’s traditional diet contained a surprisingly large amount Continue reading >>