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Ketosis And Insulin

Ketogenic Diet And Insulin Resistance

Ketogenic Diet And Insulin Resistance

Ketogenic diets around the world have been known to be extremely effective in helping improve health and lose weight fast. The diet takes into account and addresses the underlying causes of your weight gain, which could include things such as hormonal imbalances. With the ketogenic diet, you are restricting your net carb intake to under 50 grams a day. With the number of restricted carbs, your body needs to reset its way of getting the fuel that it needs. See how a diet high in healthy fats can help improve insulin resistance by changing the bodies preferred fuel source from glucose to ketones. What is Insulin and Insulin Resistance Insulin is a fat storing hormone formed by the pancreas that enables your body to manage glucose and sugars from carbs within the food. It prevents blood sugar levels from hyperglycemia or reaching too high or hyperglycemia which is too low. Insulin resistance has many symptoms including sugar cravings, weight gain, high blood pressure, high cholesterol.(1) Insulin resistance is also linked to type 2 diabetes. Therefore, cutting out or reducing sugar in your meal planning will help prevent becoming diabetic. The worrying thing about insulin resistance is symptoms take a long time to appear. When symptoms surface such as weight gain, multiple other problems may creep up. Why You Gain Weight Insulin in your body helps to regulate your blood sugar levels. Blood sugar also referred to as glucose is the primary fuel in the body for energy and brain function. When blood sugar rises, the insulin your pancreas releases move the glucose into your bloodstream. If there is glucose in your system your body will burn it first for fuel. If your body is already filled with higher glucose levels, more cannot be broken down for fuel. So because of this, your Continue reading >>

Ketosis

Ketosis

Tweet Ketosis is a state the body may find itself in either as a result of raised blood glucose levels or as a part of low carb dieting. Low levels of ketosis is perfectly normal. However, high levels of ketosis in the short term can be serious and the long term effects of regular moderate ketosis are only partially known at the moment. What is ketosis? Ketosis is a state the body goes into if it needs to break down body fat for energy. The state is marked by raised levels of ketones in the blood which can be used by the body as fuel. Ketones which are not used for fuel are excreted out of the body via the kidneys and the urine. Is ketosis the same as ketoacidosis? There is often confusion as to the difference between ketosis and ketoacidosis. Ketosis is the state whereby the body is producing ketones. In ketosis, the level of ketones in the blood can be anything between normal to very high. Diabetic ketoacidosis, also known as DKA, only describes the state in which the level of ketones is either high or very high. In ketoacidosis, the amount of ketones in the blood is sufficient to turn the blood acidic, which is a dangerous medical state. When does ketosis occur? Ketosis will take place when the body needs energy and there is not sufficient glucose available for the body. This can typically happen when the body is lacking insulin and blood glucose levels become high. Other causes can be the result of being on a low carb diet. A low level of carbohydrate will lead to low levels of insulin, and therefore the body will produce ketones which do not rely on insulin to get into and fuel the body’s cells. A further cause of ketosis, less relevant to people with diabetes, is a result of excessive alcohol consumption. Is ketosis dangerous? The NHS describes ketosis as a pote Continue reading >>

How The Ketogenic Diet Works For Type 2 Diabetes

How The Ketogenic Diet Works For Type 2 Diabetes

Special diets for type 2 diabetes often focus on weight loss, so it might seem crazy that a high-fat diet is an option. But the ketogenic (keto) diet, high in fat and low in carbs, can potentially change the way your body stores and uses energy, easing diabetes symptoms. With the keto diet, your body converts fat, instead of sugar, into energy. The diet was created in 1924 as a treatment for epilepsy, but the effects of this eating pattern are also being studied for type 2 diabetes. The ketogenic diet may improve blood glucose (sugar) levels while also reducing the need for insulin. However, the diet does come with risks, so make sure to discuss it with your doctor before making drastic dietary changes. Many people with type 2 diabetes are overweight, so a high-fat diet can seem unhelpful. The goal of the ketogenic diet is to have the body use fat for energy instead of carbohydrates or glucose. A person on the keto diet gets most of their energy from fat, with very little of the diet coming from carbohydrates. The ketogenic diet doesn’t mean you should load up on saturated fats, though. Heart-healthy fats are the key to sustaining overall health. Some healthy foods that are commonly eaten in the ketogenic diet include: eggs fish such as salmon cottage cheese avocado olives and olive oil nuts and nut butters seeds The ketogenic diet has the potential to decrease blood glucose levels. Managing carbohydrate intake is often recommended for people with type 2 diabetes because carbohydrates turn to sugar and, in large quantities, can cause blood sugar spikes. If you already have high blood glucose, then eating too many carbs can be dangerous. By switching the focus to fat, some people experience reduced blood sugar. The Atkins diet is one of the most famous low-carb, high-p Continue reading >>

Ketosis And Insulin Dependent Diabetic

Ketosis And Insulin Dependent Diabetic

Are you actually measuring/weighing your food and tracking your macronutrients? It's a nuisance, but you can't tweak it until you know what you're already doing. I'm glad you realize you need to eat fat, but how much are you eating? Have you experienced appetite suppression? How many calories are you actually eating? As others have said below, the stix don't work for everyone. You should be dropping water weight tho'. Are you drinking enough? Does insulin affect ketosis? It depends on what you mean by "affect", I think. Let's say you've been restricting your carbs to induction levels of 20g per day and you're in nutritional ketosis (regardless of what the urine test strips say - you can get a low reading simply by being well-hydrated). You are now primarily using fat for your energy. You should not be experiencing high levels of blood sugar, so your insulin requirements should be very low. EDIT - Looks like Russell more or less covered most of what you need to know. Test, test, test! Adding insulin to a metabolism that suddenly doesn't need as much can lead to serious hypoglycemia. So, does it affect ketosis? Not particularly. It DOES affect blood sugar, though, and if you're in ketosis, then by definition you have lower blood sugar levels already. One test most doctors don't run on type 2 diabetics (but should) is insulin level tests. Many people think that they are not producing enough insulin, when the reality is that they are producing tons, it just doesn't have much effect anymore. Edited by: WOUBBIE at: 7/2/2014 (09:30) 7/2/14 9:24 A by WOUBBIE I was on Metformin ( 2000 mg ) for 7 years, and still averaged over 200 mg/dl. When i started Atkins at 20 mg per day, on day 2 I woke to a 90 mg/dl reading, ate eggs, and had my first low blood sugar. Insulin, and pills l Continue reading >>

A High-fat, Ketogenic Diet Causes Hepatic Insulin Resistance In Mice, Despite Increasing Energy Expenditure And Preventing Weight Gain

A High-fat, Ketogenic Diet Causes Hepatic Insulin Resistance In Mice, Despite Increasing Energy Expenditure And Preventing Weight Gain

Go to: Low-carbohydrate, high-fat ketogenic diets (KD) have been suggested to be more effective in promoting weight loss than conventional caloric restriction, whereas their effect on hepatic glucose and lipid metabolism and the mechanisms by which they may promote weight loss remain controversial. The aim of this study was to explore the role of KD on liver and muscle insulin sensitivity, hepatic lipid metabolism, energy expenditure, and food intake. Using hyperinsulinemic-euglycemic clamps, we studied insulin action in mice fed a KD or regular chow (RC). Body composition was assessed by 1H magnetic resonance spectroscopy. Despite being 15% lighter (P < 0.001) than RC-fed mice because of a 17% increase in energy expenditure (P < 0.001), KD-fed mice manifested severe hepatic insulin resistance, as reflected by decreased suppression (0% vs. 100% in RC-fed mice, P < 0.01) of endogenous glucose production during the clamp. Hepatic insulin resistance could be attributed to a 350% increase in hepatic diacylglycerol content (P < 0.001), resulting in increased activation of PKCε (P < 0.05) and decreased insulin receptor substrate-2 tyrosine phosphorylation (P < 0.01). Food intake was 56% (P < 0.001) lower in KD-fed mice, despite similar caloric intake, and could partly be attributed to a more than threefold increase (P < 0.05) in plasma N-acylphosphatidylethanolamine concentrations. In conclusion, despite preventing weight gain in mice, KD induces hepatic insulin resistance secondary to increased hepatic diacylglycerol content. Given the key role of nonalcoholic fatty liver disease in the development of type 2 diabetes and the widespread use of KD for the treatment of obesity, these results may have potentially important clinical implications. Keywords: nonalcoholic fatty liv Continue reading >>

Insulin Sensitivity And Glucose Tolerance Are Altered By Maintenance On A Ketogenic Diet

Insulin Sensitivity And Glucose Tolerance Are Altered By Maintenance On A Ketogenic Diet

The ketogenic diet (KD) is a low-carbohydrate, high-fat diet that is used for a variety of health-related effects. This type of diet is effective at suppressing seizure activity in children with refractory epilepsy (1) and has perhaps more commonly been implemented as a dietary strategy by which weight maintenance or weight loss is the desired outcome. It has been demonstrated that restriction of dietary carbohydrates results in positive effects on cardiovascular parameters. Consuming this type of diet favorably affects body adiposity and improves features of metabolic syndrome in humans (2,3,4,5,6). Although studies evaluating the efficacy and metabolic effects of KDs have increased in recent years, the effects of macronutrient-controlled diets remain controversial in the literature. Insulin has potent short-term and long-term effects on energy intake and glucose homeostasis. In the short term, insulin release is cephalic; the brain initiates insulin secretion by directing messages through the vagus nerves to the pancreas as opposed to direct pancreatic stimulation of insulin-secreting cells. Cephalic insulin is most readily observed at the onset of a meal and consists of a short burst of insulin that is preabsorptive with regard to the ingested food. After consumption of a meal, insulin secretion increases and is sustained, because one of insulin’s roles is to prepare the body for the increase in glucose that accompanies food intake and to control the increased levels and use of glucose (7). In the long term, insulin’s role as an adiposity signal is well known, with increased plasma insulin levels resulting from increased body weight. Together, the short- and long-term effects of insulin allow for proper glucose homeostasis and assist in the regulation of body wei Continue reading >>

Insulin And Keto: What You Need To Know

Insulin And Keto: What You Need To Know

If you want to make keto really work for you, it helps to understand a little bit about how the diet does its magic and one of the big players here is the hormone insulin. Insulin does a whole lot of different things, but its best-known as the hormone that you make to metabolize carbs. Insulin gets a really bad rap in low-carb circles, to the point where it can get really oversimplified. Theres more to weight gain than insulin! For general health, insulin isnt necessarily bad , and its actually necessary for some health-related goals (for example, if you want to gain muscle, insulin is definitely your friend). But keto isnt just about general health. Keto is about a specific metabolic shift. If your goal is ketosis specifically, insulin is bad news heres what you need to know. The whole point of the ketogenic diet is that youre forcing your body to use ketone bodies for energy, instead of fat and carbohydrate. Thats what makes the diet work. Insulin suppresses ketone production . So if you want to get into ketosis and stay there, you want to minimize insulin as much as possible. Unless youre taking outside insulin, the easiest way to do this is by changing what you eat. Insulin is produced in response to different foods, so by changing your diet, you can minimize insulin production. Thats the point of a ketogenic diet. The ketogenic diet minimizes insulin production by restricting both carbs and protein the diet keeps carbs as low as possible and supplies just enough protein to meet your needs, but not more. To reduce insulin production, lower carbs Carbs raise insulin levels because you need insulin to metabolize carbs (use them for energy). The more carbs you eat, the more insulin you need. It works like this: when you eat something carb-heavy, the glucose (carbohydr Continue reading >>

The Ketogenic Diet And Insulin Resistance

The Ketogenic Diet And Insulin Resistance

We recently touched on how you can use the ketogenic diet to control symptoms of diabetes such as elevated glucose and triglycerides. In this article, we examine research showing the impact that the ketogenic diet has on levels of the hormone insulin, a key regulator of blood sugar in the body. What is Insulin’s Role in the Body? Before we look at the research, we need to know our main players. Insulin is a protein-based hormone produced by beta-cells located in the pancreas. The pancreas, which is located under the stomach, also produces enzymes that aid with digestion. Insulin’s primary purpose is to regulate the metabolism of fats and carbohydrates. The digestive system breaks down carbohydrates, such as sugars and starches, into a molecule called glucose. This compound can be used by cells to produce energy through a process called cellular respiration. Insulin allows cells in the body absorb glucose, ultimately lowering levels of glucose in the blood stream. After a meal is consumed, blood glucose levels increase and the pancreas responds by releasing insulin into the blood. Insulin assists fat, liver, and muscle cells absorb glucose from the blood, resulting in lower levels of blood glucose. Insulin stimulates liver and muscle tissues to store excess glucose as a molecule called glycogen and also reduces glucose production by the liver. When blood sugar is low, the hormone glucagon (produced by alpha-cells in the pancreas) stimulate cells to break down glycogen into glucose that is subsequently released into the blood stream. In healthy people who do not have type II diabetes, these functions allow levels of blood glucose and insulin to stay in a normal range. What Is Insulin Resistance and Why Is It a Problem? Unfortunately, for many Americans and other peopl Continue reading >>

The Ketogenic Diet And Peter Attia’s War On Insulin

The Ketogenic Diet And Peter Attia’s War On Insulin

Being a marathon runner with type 1 diabetes is tricky business. Normally, I eat a very low-carb diet which helps me maintain fairly stable blood sugar. But before a long run, I need to have enough fuel for energy, but not so much that my blood sugar gets out of control. Because this balance is so hard to achieve, I’ve found carbo-loading to be the most difficult part of my long-distance running experience. I’m always looking for a better way to do it. It turns out, there may be one. Thanks to Peter Attia’s new blog, The War on Insulin, I’m learning all about the ketogenic diet. Peter Attia was born and raised in Toronto, Canada. He studied mechanical engineering and applied mathematics as an undergrad at Queen’s University. Shortly before starting his Ph.D. in aerospace engineering, a profound personal experience led him to medical school. At Stanford Medical School, Peter believed he would become a pediatric oncologist, but by the time he started his clinical rotations he realized surgery was his passion. Peter did his residency in general surgery at the Johns Hopkins Hospital in Baltimore, Maryland and while there spent two years at the National Institutes of Health (NIH) in the National Cancer Institute as a surgical oncology fellow. About six years ago, Peter became frustrated with certain aspects of medicine and health care, in general. In particular, he grew tired of the notion that doctors did little to keep patients healthy, and were basically the last line of defense against death once patients became ill. With the concept of “preventative medicine” on his mind, and missing quantitative and analytical problem solving, Peter left medicine to join the consulting firm McKinsey & Company. Today Peter is working full-time on his passions around nutrit Continue reading >>

Dear Mark: Does Eating A Low Carb Diet Cause Insulin Resistance?

Dear Mark: Does Eating A Low Carb Diet Cause Insulin Resistance?

157 Comments Despite all the success you might have had with the Primal way of life, doubts can still nag at you. Maybe it’s something you read, or something someone said to you, or a disapproving glance or offhand comment from a person you otherwise respect, but it’s pretty common when you’re doing something, like giving up grains, avoiding processed food, or eating animal fat, that challenges deeply-and-widely held beliefs about health and wellness. It doesn’t really even matter that you’re losing weight or seem to be thriving; you may still have questions. That’s healthy and smart, and it’s totally natural. A question I’ve been getting of late is the effect of reducing carb intake on insulin sensitivity. It’s often bandied about that going low carb is good for folks with insulin resistance, but it’s also said that low carb can worsen insulin resistance. Are both true and, if so, how do they all jibe together? That’s what the reader was wondering with this week’s question: Hi Mark, I’ve been Primal for a few months now and love it. Lowering my carbs and upping my animal fat helped me lose weight and gain tons of energy (not too shabby for a middle-aged guy!). However, I’m a little worried. I’ve heard that low carb diets can increase insulin resistance. Even though I’ve done well and feel great, should I be worried about insulin resistance? Do I need to increase my carb intake? I always thought low carb Primal was supposed to improve insulin function. Vince Going Primal usually does improve insulin sensitivity, both directly and in a roundabout way. It improves directly because you lose weight, you reduce your intake of inflammatory foods, you lower systemic inflammation (by getting some sun, smart exercise, omega-3s, and reducing or dea Continue reading >>

Does Long Term Ketosis Cause Insulin Resistance?

Does Long Term Ketosis Cause Insulin Resistance?

“It’s a snake.” “It’s a wall.” “It’s a rope.” “It’s a fan.” “It’s a tree.” “It’s insulin resistance.” I’ve always been fascinated by those describing a “new finding” in medicine. I am reminded of the story of 5 men who, never having seen an elephant before, were blindfolded and asked to describe what he discovered. However, each man was introduced to a different part of the elephant. Each of them had a dramatically different description of the elephant and each made a conclusion that was very different from the others. What is fascinating, is that we usually make our “blindfolded comparisons” to those things we have seen or about which we have some descriptive understanding. Observing and describing human physiology is much like examining an elephant while blindfolded for the first time. This week’s “blind-folded finding” is what has been interpreted by some as “insulin resistance” made worse by a ketogenic diet. Really? This perked my curiosity, because I’ve personally been following a low-carbohydrate/ketogenic diet for 10 years and have thousands of patients doing the same. To this day, I’ve never seen insulin resistance “get worse.” In fact, it gets better. Clinically, it seems to take about 18-24 months to improve, but, it usually gets better. THE QUESTION – I’ve had three people from around the world contact me this week and ask why, after being on a ketogenic diet and “in ketosis,” they suddenly get a notably large blood glucose spike when they cheat. By notably large, I mean that their blood sugars rise to over 200 mg/dl within 2 hours of a carbohydrate containing meal. Now, they admit to rapid glucose recovery within an hour or two, and their hemoglobin A1c levels are subjectively normal (l Continue reading >>

Ketosis And The Ketogenic Diet: Debunking 7 Misleading Statements

Ketosis And The Ketogenic Diet: Debunking 7 Misleading Statements

Ketosis and the Ketogenic Diet: Debunking 7 Misleading Statements The ketogenic diet is the most popular dietary trend in our world today. Especially for those living with diabetes, its likely that youve been tempted to follow a ketogenic diet to lose weight, drop your A1c, and flatline your blood glucose. Even though it may seem tempting to enter the metabolic state of ketosis, its important to understand the caveats of ketosis, so that you fully understand your risks for developing long-term complications. So what exactly is a ketogenic diet? And why is ketosis a popular recommendation for those living with diabetes? A ketogenic diet a very low-carbohydrate diet by design, containing a maximum of 30 grams of dietary carbohydrate per day. When eating a ketogenic diet, you are told to avoid carbohydrate-rich foods like fruits, starchy vegetables, legumes, and whole grains, and instead eat larger quantities of meat, dairy, leafy greens, non-starchy vegetables, nuts, seeds, and vegetable oils. At the base of the ketogenic food pyramid are eggs, dairy, meat, oil, and fish, which make up the bulk of calories eaten. Non-starchy vegetables contain too much carbohydrate energy and are avoided, while non-starchy vegetables or green vegetables are included, along with nuts, seeds, and very limited amounts of fruit (mainly berries). In order to achieve the state of ketosis, you are only allowed to eat a small amount of carbohydrate energy from fruits and starchy vegetables. The ketogenic diet explicitly prohibits the consumption of grain products (even whole grains), pasta, refined sugar, milk, corn, legumes (including lentils, beans, and peas), as well as rice. When you eat a ketogenic diet, your muscle and liver switch from oxidizing glucose as their primary fuel to fatty acid Continue reading >>

Ketogenic Diet Improves Insulin Sensitivity And Numerous Aging Markers

Ketogenic Diet Improves Insulin Sensitivity And Numerous Aging Markers

A physician conducted a decade-long experiment on the health effects of a ketogenic diet, using himself as the laboratory rat; he experienced improvement in insulin sensitivity, body fat, lipids, blood sugar, and other markers A ketogenic diet requires carbohydrate and protein restriction, with 50 to 80 percent of calories coming from fats; this forces your body to shift toward using ketones as its primary fuel source, instead of glucose Although your brain is more dependent on glucose than your heart, your liver can produce a ketone-like compound that your brain can efficiently use for energy Scientists extended the lifespan of mice by 20 percent by suppressing the activity of just one gene that helps control metabolism and energy balance; this is further evidence that longevity is tied to insulin signaling The best way to jumpstart your fat-burning/ketone-producing engine is by drastically reducing your consumption of sugar and grains, fasting intermittently, and maintaining a consistent exercise routine By Dr. Mercola We are just beginning to understand the biological intricacies of aging. A growing body of research is challenging the belief that aging is beyond your control, prompting scientists to begin thinking about ways we can slow our aging clocks to a slow crawl. Although this is a relatively new branch of science, there are some factors that appear to be key in controlling how quickly you age. One major factor seems to be insulin signaling and the metabolic "engines" you have running day to day, which are largely controlled by the foods you eat. In the first featured video, Dr. Peter Attia discusses how a ketogenic diet can optimize your metabolism. But before I discuss the specifics of this, I want to tell you about a remarkable mouse study, presented in the Continue reading >>

Ketogenic Diet And Insulin Resistance

Ketogenic Diet And Insulin Resistance

What is Insulin? Insulin is a fat storing blood sugar regulating master hormone that is involved in multiple body functions beyond its metabolic role. A few examples include triglyceride and fat synthesis, electrolyte balance of sodium and potassium, feeding behaviors and cognitive and emotional brain function. What is Insulin Resistance? Insulin resistance (IR), might also known as syndrome X or metabolic syndrome, is a cluster of symptoms (weight gain, cravings and increased appetite, skin tags, gum disease, low energy) and health risk factors (abnormal, not necessarily high, blood sugar, high triglycerides and cholesterol, polycystic ovarian syndrome, high blood pressure) all resulting from abnormal insulin function. What is important to know is that just like diabetes, with IR there may be no symptoms at all. Insulin resistance is an early-stage in Type 2 diabetes but not everyone with IR will develop diabetes. Fifty percent of those with essential hypertension are insulin resistant. (1). How Many People Are Affected by Insulin Resistance? IR is more common than you think, in the United States, an estimated 60 to 70 million individuals are affected by insulin resistance, that’s 1 out of 4 people. More than 40% of individuals older than 50 years may be at risk for insulin resistance; however, it can affect anyone at any age (2) especially overweight children and adolescents regardless of race. You can connect with this link to see a table of the prevalence of insulin resistance by country. Causes of Insulin Resistance There are several causes of insulin resistance: Genetics and family history of diabetes, pre-diabetes Ethnic origin (African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, or Pacific Islander American) Age Hormone malfuncti Continue reading >>

Are You Insulin Resistant?

Are You Insulin Resistant?

Finding out you are insulin resistant doesn't mean much unless you understand what that implies, and how it effects your health. Insulin resistance is an condition in which the body is not responding properly to the hormone insulin. If faulty insulin signaling is not treated, it can develop into worsening conditions of metabolic syndrome, pre diabetes, and finally type 2 diabetes. What Causes the Insulin Resistant Condition? The insulin resistant condition is rooted in the metabolic effects of a high carb diet in combination with a lack of exercise. Weight gain is a symptom of insulin resistance, rather than a cause. Carbohydrates are foods which contain either some form of sugar or starch, or both. For instance, orange juice is full of fructose, a type of sugar, and white potatoes contain large amounts of starch. Both types of carbohydrate are broken down in the body into glucose, a simple sugar, which your cells can use for energy to do all the things that cells do. Since too much glucose in your body can be toxic, your pancreas releases a powerful hormone called insulin. Insulin works to control the amount of glucose in your bloodstream. It acts to quickly move glucose from your bloodstream and push it into your cells where it can be burned or stored. But there's a catch. To get the glucose into the cells, the cell's glucose "storage tanks" have to be empty. This is logical when you think about it. Imagine what would happen if you tried to fill up your car's gas tank if it were already full. And just like running a car burns up gasoline, when a person exercises, the glucose which is already in the glucose tanks get used. Now there is room for insulin to push the glucose made from the last meal into the muscle cell for fuel. If a person exercises frequently, lots of c Continue reading >>

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