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Ketosis And Brain Function

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Ketosis Fundamentals

What is ketosis? Ketosis is the physiological state where the concentration of ketone bodies in the blood is higher than normal. This is generally agreed to be at beta-hydroxybutyrate (BHB) concentrations greater than 0.5 mM. How to achieve ketosis? Ketosis occurs either as a result of increased fat oxidation, whilst fasting or following a strict ketosis diet plan (ENDOGENOUS ketosis), or after consuming a ketone supplement (EXOGENOUS ketosis). When in a state of ketosis the body can use ketones to provide a fuel for cellular respiration instead of its usual substrates: carbohydrate, fat or protein. Why does ketosis exist? Normally, the body breaks down carbohydrates, fat, and (sometimes) proteins to provide energy. When carbohydrate is consumed in the diet, some is used immediately to maintain blood glucose levels, and the rest is stored. The hormone that signals to cells to store carbohydrate is insulin. The liver stores carbohydrate as glycogen, this is broken down and released between meals to keep blood glucose levels constant. Muscles also store glycogen, when broken down this provides fuel for exercise. Most cells in the body can switch readily between using carbohydrates an Continue reading >>

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Popular Questions

  1. _pickleliquor_

    A bit over a year ago I started noticing difficulties with speaking, occasionally. I'd often completely blank on a word and stop talking midsentence, and kept using one tense of a word when I meant to use another. I wasn't having any issues thinking or writing, just talking. I was being screened for some other neurological issues at the time and came back with a clean bill of health, so I just assumed this was the dreaded "brain fog" that was a consequence of living too many years as a diabetic or just my age catching up with me (I'm 27).
    I've been on keto about six months, and it recently occurred to me that my tense misuse had virtually disappeared. Went off of keto for a few days last week, and just like magic, it was back.
    Just thought it was an interesting anecdote, and I'm curious if anyone else has noticed similar effects. I never really got the noticeable sustained energy boost or mental clarity that a lot of people feel on keto, but it's clearly still doing something for me.

  2. IllConceivedIdeas

    The cells in your brain quite literally work using different systems when you're in ketosis to such an extent that it's being actively researched for possible use in combating alzheimers, bpd and autism disorders.
    It's incredible just how many things it changes and how little we truly know about what exactly is going on.

  3. IllConceivedIdeas

    btw, just how far off did you go? Was it a lot of carbs or just a few more than your limit? Was a lot of sugar involved? You don't have to answer, but I'd be curious to know if you think there was any more to it than simply not being in ketosis.

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