Ketosis Acidosis

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Is Ketosis Dangerous?

You may have heard from your doctor that ketosis is a life-threatening condition. If so, your doctor is confusing diabetic ketoacidosis (DKA) with nutritional ketosis, or keto-adaptation. First, some semantics. Our body can produce, from fat and some amino acids, three ketone bodies (a “ketone” refers to the chemical structure where oxygen is double-bonded to carbon sandwiched between at least 2 other carbons). These ketone bodies we produce are: acetone, acetoacetone, and beta-hydroxybutyrate (B-OHB). [For anyone who is interested, they are the 3 most right structures on the figure, below.] Why do we make ketones? For starters, it’s a vital evolutionary advantage. Our brain can only function with glucose and ketones. Since we can’t store more than about 24 hours’ worth of glucose, we would all die of hypoglycemia if ever forced to fast for more than a day. Fortunately, our liver can take fat and select amino acids (the building blocks of proteins) and turn them into ketones, first and foremost to feed our brains. Hence, our body’s ability to produce ketones is required for basic survival. What is diabetic ketoacidosis? When diabetics (usually Type I diabetics, but some Continue reading >>

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Popular Questions

  1. borntobethin35

    Yesterday I notice the last few seconds of urinating, I would get this tingling sensation (not really burning) in my stomach. So I went to the Dr (not the one that did the surgery but my main doctor) and she stated I have a UTI. She prescribe some antibotics that taste really nasty (since I crush them up)
    Of course the Dr checks your urine. She told me I was in Ketosis stage and I'm starving myself. I just looked at her and reminder her that I did just have VSG and basically I do eat, just not a whole lot any more. I hate to have a UTI right now but I am happyh to ketosis stage meaning I'm burning fat/calories.
    Has any one else been told they are Ketosis? If so, is this bad and how long does it last? It seems like something you want to last forever if you are burning fat, right?

  2. Danielle K.

    All of us should be in ketosis while in the losing stage. When you hit maintenance you start increasing your carbs and it evens out for your body. You don't want to be in ketosis forever, from a medical stand point. It could be bad for your kidneys and cause renal failure in the long run.

  3. Jennchap

    I have been in Ketosis since surgery. I bought the walgreens brand ketosticks for 10 bucks and check a few times a week. It will be 12 weeks this Thursday and Im down 45 pounds and been in Ketosis the whole time. I was in ketosis the last 3 months of my last pregnancy and never had any issues so Im not worried but sure as hell enjoying the fat burning baby cakes!

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Diabetic Ketosis Without Acidosis

Ketosis and Ketonuria Ketosis and Ketonuria may occur whenever increased amounts of fat are metabolized, carbohydrate intake is restricted, or the diet rich in fats (either “hidden” or obvious). This state can occur in the following situations: a. Metabolic conditions: Diabetes mellitus Renal glycosuria Glycogen storage disease (von Gierke’s disease) b. Dietary conditions: Starvation, fasting High-fat diets Prolonged vomiting, diarrhea Anorexia Low-carbohydrate diet Eclampsia c. Increased metabolic states caused by: Hyperthyroidism Fever Pregnancy or lactation In non-diabetic persons, ketonuria occurs frequently during acute illness, severe stress, or sternous exercise. Approximately 15% hospitalized patients have ketones in their urine even though they do not have diabetes. Children are particularly prone to developing ketonuria and ketosis. Ketonuria signals a need for caution, rather than crisis intervention, in either a diabetic or non-diabetic patient. However, this condition should not be taken lightly. In the diabetic patients, ketone bodies in the urine suggest that the diabetes is not adequately controlled and that adjustments of either the medication or diet should Continue reading >>

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Popular Questions

  1. eager2bMD

    Can someone please explain to me why alcohols are more acidic than both aldehydes and ketones?
    From my rationalization, I would think it would be the other way around because the more acidic molecule will be the one whose conjugate base is most stable. The carbonyl group on aldehydes and ketones is electron-withdrawing, which would stabilize the negative charge better, so wouldn't this make their conjugate bases more stable and thus make aldehydes and ketones more acidic?
    If somebody could please tell me where my logic is wrong, I would realllly appreciate it! Thanks!!!

  2. Bruinsfinalfour

    eager2bMD said: ↑
    Can someone please explain to me why alcohols are more acidic than both aldehydes and ketones?
    From my rationalization, I would think it would be the other way around because the more acidic molecule will be the one whose conjugate base is most stable. The carbonyl group on aldehydes and ketones is electron-withdrawing, which would stabilize the negative charge better, so wouldn't this make their conjugate bases more stable and thus make aldehydes and ketones more acidic?
    If somebody could please tell me where my logic is wrong, I would realllly appreciate it! Thanks!!! Your logic is wrong in that if you de-protonate an aldehyde/ketone...you are left with an ionic carbon atom...which you should know is extremely unstable. When you de-protonate an alcohol, you are left with an ionic oxygen atom which is much more stable (bigger, more electronegative)

  3. eager2bMD

    Thanks Bruins! By focusing on little details, I completely neglected the most basic principles. Thanks for the help!

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

Ketosis & Acidosis

Ketosis occurs when the fat in your body does not break down completely, producing ketones. It's a condition that can occur when you go on a low-carb diet and glycogen stores in your liver are depleted. When you have too much acid in your system, you can develop acidosis. The acid build-up can take place in your kidneys or lungs for a variety of reasons. The build-up of ketones can cause an imbalance that leads to excessive acid production. Video of the Day Diabetics may be prone to ketosis or acidosis when insulin levels drop below healthy levels or when ketones build up in the body due to uncontrolled insulin levels. Ketones are the byproduct produced when the body relies primarily on fat stores for energy. While short-term ketosis can help you lose weight, ketones that continue to build up in your blood and urine are poisonous and lead to diabetic ketoacidosis, also referred to as diabetic acidosis. The condition is a more common complication of Type 1 diabetes. In addition to low insulin levels, trauma, severe infection, a heart attack or surgery can lead to diabetic ketoacidosis. Diabetic acidosis requires immediate medical attention. As insulin levels drop, your body produces Continue reading >>

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Popular Questions

  1. Import

    Hi there, I've read older posts about ketones and ketosis and about seeing these things in your urine. What do they look like?

  2. Import

    HAHAHAHAHAHAHAHhahahahaah... Okay, Ketones? HAHHAAAHAHAAA..hahaa... okay seriously. You have to go get the KetoSticks to measure your urine. As far I know they are not little creatures swimming in your urine. As cool as that does sound...

  3. Import

    Ketones are released when your body is in ketosis, which is basically hardcore fat burning mode. Certain toxins are stored in fat, among other things. Burning fat releases all this stuff into your blood stream, and it shows up in your urine. You cannot see ketones, you use urine testing strips to check your ketone content.

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