Ketones In Urine During Pregnancy
Ketones in the urine during pregnancy is a health concern which some women experience during those crucial nine months. Although, it is not a high-risk pregnancy complication, studies reveal that it can be a cause of worry. Ketones are substances derived from fat breakdown. They are used by the body as a source of energy under emergency circumstances, like starvation or glucose deficiency, in order to survive. In other words, ketones in the urine are formed when the body's fat reserves are used to generate energy. Ketones in the blood further leads to ketosis. Weakness, nausea, lethargy, and excess sweating are signs of ketosis. Occurrence Our body gets its energy from the food we eat, which gets converted into glucose or blood sugar. It is insulin which provides an easy access to this blood sugar. During pregnancy, the placental hormones make the body resistant to insulin, which subsequently restricts the glucose in the blood from entering the cells. Hence, though the blood will be enriched with blood sugar, the cells will be deprived of the required energy. As a result, the cells start accessing other energy sources, like the fat stores, resulting in ketones as the byproduct of this entire process. Causes There can be various factors that may contribute to large ketones in the urine during pregnancy; dehydration and bad diet, to name a few. Others are enlisted below: ➤ Not getting enough calories from the food you are eating ➤ Long time intervals between meals ➤ Skipping meals or snacks ➤ Gestational diabetes ➤ Diets which include low intake of carbohydrates ➤ Dehydration - not drinking enough water ➤ Metabolic disorders ➤ Nausea, poor eating habits or throwing up ➤ Insulin resistance from hormones as a result of which the body is unable to access bl Continue reading >>
Ketones In Urine
I know this is an old post, but people may still be checking for answers. I work in a laboratory where we do urinalysis constantly all day every day. In a pregnant woman, you can see ketones in the urine in two, but separate, circumstances. First is ketones in combination with any urine glucose (sugar) level. This may be a sign of gestational diabetes and you should start asking your doctor questions about it. Second is ketones by themselves. I'm 12 weeks pregnant and had ketones in my urine and was instructed by my doctor to go to the ER and get IV fluids. This was directly related to my eating habits, which at that point were near null because of the morning sickness. Because I was eating so little, and barely able to keep water down, my body was using my fat stores to supply nutrients to the baby. This breakdown of fat in such large amounts causes ketones as a waste product, which is then excreted through your urine. Ketones occur in the absence of carbs, when your body starts to use fat for calories. You will see ketones when you are eating very low calorie, very low carb, or have impaired insulin function. Ketones are concentrated in a state of dehydration. Excess glucose in urine indicates eating too many carbs (if you're diabetic) and/or impaired insulin function. Both are hallmarked by sweet smelling urine. Make sure you eat small meals during the day and add a night time snack, with a protein, to prevent ketosis while sleeping. If you think you have diabetes see a physician. I am 38 weeks pregnant and my urin showed high ketones this week. My blood sugar was in "acceptable" level; however, my doctor said that the presence of ketones in my urine means I need to drink alot more water because my body is converting carbs to sugar faster than I can exp Continue reading >>
What Is It? Diabetic ketoacidosis is a potentially fatal complication of diabetes that occurs when you have much less insulin than your body needs. This problem causes the blood to become acidic and the body to become dangerously dehydrated. Diabetic ketoacidosis can occur when diabetes is not treated adequately, or it can occur during times of serious sickness. To understand this illness, you need to understand the way your body powers itself with sugar and other fuels. Foods we eat are broken down by the body, and much of what we eat becomes glucose (a type of sugar), which enters the bloodstream. Insulin helps glucose to pass from the bloodstream into body cells, where it is used for energy. Insulin normally is made by the pancreas, but people with type 1 diabetes (insulin-dependent diabetes) don't produce enough insulin and must inject it daily. Your body needs a constant source of energy. When you have plenty of insulin, your body cells can get all the energy they need from glucose. If you don't have enough insulin in your blood, your liver is programmed to manufacture emergency fuels. These fuels, made from fat, are called ketones (or keto acids). In a pinch, ketones can give you energy. However, if your body stays dependent on ketones for energy for too long, you soon will become ill. Ketones are acidic chemicals that are toxic at high concentrations. In diabetic ketoacidosis, ketones build up in the blood, seriously altering the normal chemistry of the blood and interfering with the function of multiple organs. They make the blood acidic, which causes vomiting and abdominal pain. If the acid level of the blood becomes extreme, ketoacidosis can cause falling blood pressure, coma and death. Ketoacidosis is always accompanied by dehydration, which is caused by high Continue reading >>
Dehydration In Children - Treatment
A A A Dehydration in Children (cont.) Be concerned if your child has an excessive loss of fluid by vomiting or diarrhea, or if the child refuses to eat or drink. Signs of dehydration include: Sunken eyes Decreased frequency of urination or dry diapers Sunken soft spot on the front of the head in babies (called the fontanel) No tears when the child cries Dry or sticky mucous membranes (the lining of the mouth or tongue) Lethargy (less than normal activity) Irritability (more crying, fussiness with inconsolability) Infants and small children can become dehydrated quickly. Contact your doctor if your child has any of the following: Crying without tears No urine output for over a period of four to six hours Sunken eyes Blood in the stool Vomiting for more than 24 hours, or vomiting that is consistently green in color Fever higher than 103 F (39.4 C) Less activity than usual Urination much more than usual If your child is lethargic (difficult to awaken) If you cannot reach your doctor If your child's mouth looks dry The doctor will perform a thorough history and physical exam in an effort to determine the severity and cause of the dehydration. Specific laboratory tests may be ordered. A complete blood count may identify an infection. Blood cultures may identify the specific kind of infection. Blood chemistries may identify electrolyte abnormalities caused by vomiting and diarrhea Urinalysis may identify bladder infection, may give evidence of the severity of dehydration, and may identify sugar and ketones in urine (evidence of uncontrolled diabetes). In some cases, the doctor may order other tests, such as a chest X-ray, a test to check for rotavirus, stool cultures, or lumbar puncture (a spinal tap). Continue Reading A A A Dehydration in Children (cont.) Dehydration in chil Continue reading >>
How Much Do You Know About Ketones?
Most people with diabetes – and anyone who has read about low-carbohydrate diets – has probably heard of ketones, but how many people really know what they are? Messages about ketones can be confusing: Some sources say they are toxic and dangerous, while others suggest that ketones are a positive sign of weight loss through fat burning. When you have diabetes, it’s important to know the facts about ketones, as well as when to check for them, how to check for them, and what to do if you detect them. Take this quiz to see how much you know about ketones. (You’ll find answers later in this article.) Q 1. What are ketones? A. Acids created in the liver. B. Fats released when blood glucose is high. C. Antifungal drugs. D. Hormones that are created only under special circumstances. 2. Which of the following statements about ketones is not true? A. Consuming very little carbohydrate can lead to the formation of ketones. B. Trace levels of ketones are generally harmless. C. There must be a very low level of insulin for dangerous amounts of ketones to form. D. Ketones cause weight loss. 3. All persons with diabetes should check for ketones when their blood glucose level is over 240 mg/dl. TRUE FALSE 4. Ketones can only be measured in the urine. TRUE FALSE 5. What is the role of ketones in the development of diabetic ketoacidosis (DKA), the acute diabetes complication characterized by high levels of ketones, high blood glucose, and dehydration? (More than one answer may be correct.) A. Ketones make the blood more acid. B. High levels of ketones cause dehydration. C. Ketones play a role in electrolyte loss. D. Ketones raise blood glucose. 6. People with Type 2 diabetes cannot develop diabetic ketoacidosis. TRUE FALSE 7. What steps are necessary to reduce ketones in the bod Continue reading >>
Value Of Point-of-care Ketones In Assessing Dehydration And Acidosis In Children With Gastroenteritis.
Abstract OBJECTIVES: Children with gastroenteritis often develop dehydration with metabolic acidosis. Serum ketones are frequently elevated in this population. The goal was to determine the relationship between initial serum ketone concentration and both the degree of dehydration and the magnitude of acidosis. METHODS: This was a secondary analysis of a prospective trial of crystalloid administration for rapid rehydration. Children 6 months to 6 years of age with gastroenteritis and dehydration were enrolled. A point-of-care serum ketone (beta-hydroxybutyrate) concentration was obtained at the time of study enrollment. The relationship between initial serum ketone concentration and a prospectively assigned and previously validated clinical dehydration score, and serum bicarbonate concentration, was analyzed. RESULTS: A total of 188 patients were enrolled. The median serum ketone concentration was elevated at 3.1 mmol/L (interquartile range [IQR] = 1.2 to 4.6 mmol/L), and the median dehydration score was consistent with moderate dehydration. A significant positive relationship was found between serum ketone concentration and the clinical dehydration score (Spearman's rho = 0.22, p = 0.003). Patients with moderate dehydration had a higher median serum ketone concentration than those with mild dehydration (3.6 mmol/L vs. 1.4 mmol/L, p = 0.007). Additionally, the serum ketone concentration was inversely correlated with serum bicarbonate concentration (ρ = -0.26, p < 0.001). CONCLUSIONS: Children with gastroenteritis and dehydration have elevated serum ketone concentrations that correlate with both degree of dehydration and magnitude of metabolic acidosis. Point-of-care serum ketone measurement may be a useful tool to inform management decisions at the point of triage or in Continue reading >>
Clinical Significance Of Positive Urine Ketone Result
Ketone bodies are usually absent in urine. The presence of ketones in the urine probably indicates that the body is using fats rather than carbohydrates for energy. High levels of ketones may be present in the urine of individuals with uncontrolled diabetes because the body's ability to metabolize carbohydrates is defective. Detecting the presence of ketones in the urine is a valuable aid to managing and monitoring individuals with diabetes mellitus. Ketonuria is an indication that the insulin dose needs to be increased. Electrolyte imbalance and dehydration occur when ketones accumulate in the blood. If these conditions are not corrected by adjusting the dose of insulin, the patient may develop ketoacidosis and ultimately diabetic coma. Low levels of ketones may be detected during conditions of physiological stress such as fasting, rapid weight loss, frequent strenuous exercise or prolonged vomiting. The presence of ketones in these situations is due to either inadequate intake of carbohydrates or increased loss of carbohydrates. Continue reading >>
The Facts Diabetic ketoacidosis (DKA) is a condition that may occur in people who have diabetes, most often in those who have type 1 (insulin-dependent) diabetes. It involves the buildup of toxic substances called ketones that make the blood too acidic. High ketone levels can be readily managed, but if they aren't detected and treated in time, a person can eventually slip into a fatal coma. DKA can occur in people who are newly diagnosed with type 1 diabetes and have had ketones building up in their blood prior to the start of treatment. It can also occur in people already diagnosed with type 1 diabetes that have missed an insulin dose, have an infection, or have suffered a traumatic event or injury. Although much less common, DKA can occasionally occur in people with type 2 diabetes under extreme physiologic stress. Causes With type 1 diabetes, the pancreas is unable to make the hormone insulin, which the body's cells need in order to take in glucose from the blood. In the case of type 2 diabetes, the pancreas is unable to make sufficient amounts of insulin in order to take in glucose from the blood. Glucose, a simple sugar we get from the foods we eat, is necessary for making the energy our cells need to function. People with diabetes can't get glucose into their cells, so their bodies look for alternative energy sources. Meanwhile, glucose builds up in the bloodstream, and by the time DKA occurs, blood glucose levels are often greater than 22 mmol/L (400 mg/dL) while insulin levels are very low. Since glucose isn't available for cells to use, fat from fat cells is broken down for energy instead, releasing ketones. Ketones accumulate in the blood, causing it to become more acidic. As a result, many of the enzymes that control the body's metabolic processes aren't able Continue reading >>
Urine Ketones - Meanings And False Positives
Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find the Urine Ketones article more useful, or one of our other health articles. Description Ketones are produced normally by the liver as part of fatty acid metabolism. In normal states these ketones will be completely metabolised so that very few, if any at all, will appear in the urine. If for any reason the body cannot get enough glucose for energy it will switch to using body fats, resulting in an increase in ketone production making them detectable in the blood and urine. How to test for ketones The urine test for ketones is performed using test strips available on prescription. Strips dedicated to ketone testing in the UK include: GlucoRx KetoRx Sticks 2GK® Ketostix® Mission® Ketone Testing should be performed according to manufacturers' instructions. The sample should be fresh and uncontaminated. Usually the result will be expressed as negative or positive (graded 1 to 4). Ketonuria is different from ketonaemia (ie presence of ketones in the blood) and often ketonuria does not indicate clinically significant ketonaemia. Depending on the testing strips used, urine testing for ketones either has an excellent sensitivity with a low specificity, or a poor sensitivity with a good specificity. However, this should be viewed in the context of uncertainty of the biochemical level of significant ketosis. Interpretation of results Normally only small amounts of ketones are excreted daily in the urine (3-15 mg). High or increased values may be found in: Poorly controlled diabetes. Starvation: Prolonged vomiting. Rapid weight loss. Frequent strenuous exercise. Poisoning (eg, with isop Continue reading >>
What Are Ketones And Their Tests?
A ketone test can warn you of a serious diabetes complication called diabetic ketoacidosis, or DKA. An elevated level of this substance in your blood can mean you have very high blood sugar. Too many ketones can trigger DKA, which is a medical emergency. Regular tests you take at home can spot when your ketone levels run too high. Then you can take insulin to lower your blood sugar level or get other treatments to prevent complications. What Exactly Are Ketones? Everyone has them, whether you have diabetes or not. Ketones are chemicals made in your liver. You produce them when you don't have enough of the hormone insulin in your body to turn sugar (or “glucose”) into energy. You need another source, so your body uses fat instead. Your liver turns this fat into ketones, a type of acid, and sends them into your bloodstream. Your muscles and other tissues can then use them for fuel. For a person without diabetes, this process doesn’t become an issue. But when you have diabetes, things can run out of control and you build up too many ketones in your blood. If the level goes too high, it can become life-threatening. Who Needs a Ketone Test? You might need one if you have type 1 diabetes. In this type, your immune system attacks and destroys cells in your pancreas that make insulin. Without it, your blood sugar rises. People with type 2 diabetes can also get high ketones, but it isn't as common as it is with type 1. Tests can show you when your level gets high so you can treat it before you get sick. When Should You Test? Your doctor will probably tell you to test your ketones when: Your blood sugar is higher than 250 milligrams/deciliter (mg/dl) for two days in a row You're sick or you've been injured You want to exercise and your blood sugar level is over 250 mg/dl Continue reading >>
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Department Of Emergency Medicine | Dehydration
In young children, mild to moderate dehydration can happen very easily, particularly if the child has been in hot weather without drinking a sufficient amount of fluids, or if she has been experiencing diarrhea and/or vomiting. Timely and appropriate care is crucial in the assessment and management of dehydration in children because inadequate treatment can lead to serious, but preventable, complications. Although prevention is ideal, in some cases—like with excessive vomiting and diarrhea brought on by a bad “stomach flu”—dehydration is challenging to prevent. Making an accurate assessment that the child is dehydrated, or at serious risk of becoming dehydrated, is the single most important factor in making and carrying out the proper treatment decisions. Assessing dehydration If you suspect a child may be dehydrated, performing a thorough history and physical examination should be enough to confirm the diagnosis, help determine its cause and establish its severity. Factors like sunken eyes, crying without tears, lethargy, decreased frequency and/or volume of urination and fussiness are some of the signs of dehydration in children. Depending on the situation, a provider may perform the following tests to determine whether there is an underlying cause to the child's dehydration: blood count to determine the presence of a serious infection blood cultures to identify the type of bacterial infection blood chemistry to identify any electrolyte abnormality urinalysis to identify bladder infection, give evidence of severity of dehydration and/or identify sugar and ketones in urine (indicating inadequately treated diabetes) Managing dehydration in children Children who are dehydrated should begin treatment with oral re-hydration solutions (ORS), which help replace not j Continue reading >>
Top 30 Doctor Insights On: Ketones In Urine Dehydration
1 It may: It is imperative to repeat the urine test once you have fully recovered from pancreatitis. It is also important to find out what precipitated pancreatitis and avoid those stimuli. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and ...Read more Continue reading >>
Ketosis: Why Women Need To Drink Their Way Through Labour
If you labour for a long time, you could be in danger of dehydration and developing complications such as ketosis. Here’s how to keep yourself safe and healthy during birth. There's so much going on during labour that the last thing that either you, or your birth partner, may think of is getting you to drink enough. Not that sort of drink obviously. There's no ordering a cheeky mojito with your epidural but you do need to keep your intake of water up when you're giving birth if you want to stay healthy, hydrated and keep any chance of developing a nasty case of ketosis at bay. What is ketosis? Ketosis is a complication of dehydration, and a lack of carbohydrates (or glucose) for energy in the body. It is the result of the abnormal accumulation of ketone bodies in the blood stream, body tissues and urine. When does ketosis occur? Ketosis happens when the muscles have little, or no, glucose for energy to be able to function efficiently. Once the glucose supply in the blood stream is depleted, the body starts to break down its fat stores for energy instead. This produces ketones, often causing a fever, body weakness and the muscles to function inefficiently, including the uterus. In cases where the ketosis is prolonged, the condition can develop into ketoacidosis. Ketoacidosis makes the person feel unwell and can damage their body organs. This is something that can occur for people who have uncontrolled diabetes. Ketosis and labour Ketosis is a common outcome for women who experience a prolonged labour (or pre-labour), becoming dehydrated and often causing their contractions to weaken, slow or stop. This can start to happen if glycogen (or glucose) is not being replenished through eating and drinking during labour. During labour, a woman has high-energy needs and her sto Continue reading >>
Dangers Of Dehydration & Ketones In Pregnancy
I just spent the last weekend in the hospital getting a lesson from my doctor on the dangers of dehydration and ketones. It's common enough in pregnancy that I felt I would share with all of you. I was not even aware I was dehydrated, as I didn't feel any of the symptoms I will describe below. What is dehydration? Simply put, it's where your body eliminates more water than is being replaced. In your first trimester this is usually brought on my vomiting caused by "morning" sickness. Other culprits can be airplane travel and humidity. It is vitally important that you are drinking plenty of water throughout the entire day. A good rule of thumb is one glass for you; one glass for baby once per hour. Later in pregnancy, 2nd and 3rd trimester, dehydration can cause preterm labor. Actually, dehydration is the third most common reason that women experience preterm labor. When your doctor has you pee in a cup, they are checking for many things, one of them being dehydration and the other being ketones. Dehydration Symptoms: Signs and symptoms of dehydration include: Thirst. This is the first sign, and probably the most ignored. Listen to your body – if you’re thirsty, your body is trying to tell you something. You should try to maintain a schedule of drinking at least one glass of water an hour (more if needed). Dizziness. Dehydration may lead to feelings of dizziness, lightheadedness or vertigo, especially when standing up, bending over, or kneeling. This dizziness symptom is due to low blood pressure caused by dehydration. Headaches. Dehydration is a major cause of headaches, particularly migraines, in pregnant moms and non-pregnant folks alike. Don’t dismiss your headaches as hormonal (although, those can be a contributor). Make sure you’re drinking at least 10 pints Continue reading >>
10 Things Your Pee Can Tell You About Your Body: Taking A Deep Dive Into Urinalysis, Dehydration, Ketosis, Ph & More!
See, for the past several days, I’ve been randomly grabbing drinking glasses from the shelf in the kitchen… …and peeing into them. And yes, I realize that now you will likely never want to join me at my home for a dinner party. So why the heck am I urinating into our family’s kitchenware? It’s all about better living through science and figuring out ways to live longer and feel better (at least that’s what I tell my wife to appease her). It’s also about my sheer curiosity and desire to delve into an N=1 experiment in self-quantification with urinalysis. It’s also because I’ve been too lazy to order one of those special urinalysis specimen cups with the cute plastic lid. And let’s face it: with my relatively frequent use of a three day gut testing panel, my wife is already somewhat accustomed to giant Fed-Ex bags full of poop tubes sitting in the fridge, so urine can’t be all that bad, right? Anyways, in this article, you’re going to learn exactly why I think it’s a good idea to occasionally study one’s own urine, and you’ll also discover 10 very interesting things your pee can tell you about your body. Enjoy, and as usual, leave your questions, thoughts, feedback, and stories of your own adventures in urinalysis below this post. ———————– The History Of My Interest In Urinalysis Two years ago, I first became interested in urinalysis when I discovered a new start-up called “uChek”. The premise of uChek was quite simple. People with diabetes who want to check the amount of glucose in their urine would simply be able to download uChek to their iPhone or iPad. Then, after a “mid-stream collection,” (yes, that’s exactly what it sounds like and, in my experience, despite my Private Gym training, can be quite difficult to Continue reading >>