Ketones In Urine Causes

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Are Blood Ketones A Better Predictor Than Urine Ketones Of Acid Base Balance In Diabetic Ketoacidosis?

Abstract Detection of ketonaemia is a key factor in diagnosing diabetic ketoacidosis (DKA). Measurement of urinary ketones via the nitroprusside reaction is the most commonly employed diagnostic test; however, near patient testing of blood ketones is now widely available. In the clinical setting we wished to compare the utility of urine and blood ketone measurements to predict acid base balance and need for admission in patients with type 1 diabetes. A retrospective study was performed on 52 patients referred to the metabolic or acute receiving units of a teaching hospital. Urine and capillary ketone measurements, blood gas analysis and/or venous bicarbonate measurement were analysed together with the clinical outcome of either admission or discharge of the patient. Capillary β-hydroxybutyrate measurement gave a strong negative correlation (r -0.771; p<0.001) with serum bicarbonate concentration. Urine ketone measurement showed a weaker negative correlation (r -0.493; p<0.001) with bicarbonate levels. There was no difference in the ability to predict hospital admission between blood ketone measurement and urine ketone measurement )positive predictive value 84.6% [95% confidence in Continue reading >>

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Popular Questions

  1. crush1staid - 01/17/10 19:33

    well u know half the answer , there is shift from intra to extra cellular ,thus the patient will have Hyper K and when we treat DKA we MUST give the maintance of K bcz insulin will shift K to inra cellular.
    If not giving K with tx then we will produce Hypo K .
    In ICU treating DKA ,K started after making sure pt is urinating.
    I hope this will help.

  2. studyin4ck - 01/18/10 04:29

    so is it right to say total body pottasium is decreased but serum potassium is increased.

  3. eurogirl - 01/19/10 09:40

    You are right guest123, this is the thing!

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