Can Ketone Drinks Really Boost Your Workouts?
A new company is selling Ketone drinks with a promise of boosting your exercises. However, the research is mixed and the little bottles aren’t cheap. A San Francisco start-up is now bottling and selling what they call human “superfuel.” Human-performance company HVMN (pronounced “human”) says their new drink can help you improve athletic performance, boost energy, and even enhance focus and concentration. What’s in this clear, odorless liquid that comes in a petite, shot-sized bottle? It has 120 calories, no fat, no protein, and no carbohydrates. But it does contain what the company’s top executive believes is the “fourth macronutrient” — pure ketone ester. “Ketones are used as highly-efficient fuel for the brain and body,” Geoff Woo, co-founder and chief executive officer of HVMN, told Healthline. Woo says his company’s new drink, called Ketone, harnesses the power of ketones in a ready-to-consume fuel for humans. Unlike today’s energy drinks and sports supplements, Woo says Ketone relies on the body’s own reserves for natural fuel and sustained energy. Ketones deliver a performance boost that is “unlike anything we've ever seen before,” said Kieran Clarke, a professor of physiological biochemistry at Oxford University in the United Kingdom, in an interview with Business Insider. Clarke and her colleagues study ketones. They’ve been working with Woo and HVMN to translate their findings into a consumable product. The product isn’t cheap. One of the 2.2-ounce bottles costs more than $30. What are ketones? Ketones are compounds produced by your liver when your body is unable to use its preferred source of energy, carbohydrates. Almost all foods contain carbohydrates. When you eat them, your body turns those carbohydrates into sugar, o Continue reading >>
Exogenous Ketones: What They Are, Benefits Of Use And How They Work
Exogenous ketones have become a popular nutritional supplement since their introduction in 2014. Like with any new supplement, though, there tends to be a lot of misinformation that you have to sift your way through to find the reliable data. So, this article does the hard work for you and gets right to what the true benefits and drawbacks of exogenous ketones are. We also cover what forms of ketones to consider, how they function in the body, and their role in future research. What Are Ketones? Our bodies use ketones via our mitochondria to generate energy. They are an alternative fuel source to glucose. Ketones are simple compounds because of their small molecular structure and weight. Specifically, they are organic (carbon-based) compounds that contain a central carbon atom double-bonded to an oxygen atom and two carbon-containing substituents, denoted by “R” (see chemical structure below). In humans, there are 3 different ketones produced by the mitochondria of the liver. These are also often referred to as ketone bodies. The three ketones are: Acetone Acetoacetic Acid Beta-Hydroxybutyric Acid (also known Beta Hydroxybuyrate or BHB). Other chemical names include 3-hydroxybutyric acid or 3-hydroxybutyrate. BHB is not technically a ketone since it contains a reactive OH-group in place of where a double-bonded oxygen normally would be as you can see in the diagram below. Yet, BHB still functions like a ketone in the body and converts into energy much like acetoacetate and acetone. This happens via the acetoacetate and acetyl-CoA pathway. Note that acetone conversion to acetyl-CoA is not efficient due to the need to convert acetone to acetoacetate via decarboxylation. However, BHB still functions like a ketone in the body and can be converted to energy (via acetoace Continue reading >>
Calories In Pruvit Ketone Drink
Nutrition Facts pruvit - Ketone Drink Calories 45 Sodium 910 mg Total Fat 0 g Potassium 0 mg Saturated 0 g Total Carbs 6 g Polyunsaturated 0 g Dietary Fiber 0 g Monounsaturated 0 g Sugars 0 g Trans 0 g Protein 0 g Cholesterol 0 mg Vitamin A 0% Calcium 24% Vitamin C 0% Iron 0% *Percent Daily Values are based on a 2000 calorie diet. Your daily values may be higher or lower depending on your calorie needs. Continue reading >>
Ketones: Secret Weapons In Fitness And The Fight Against Fat?
If you’ve been hearing all the chatter about the latest health and fitness fad, you may well be wondering what all the fuss is about ketones. From diets to supplements, there are a lot of different ways to “go keto.” The ketogenic diet, which was first developed in the 1900s, bears striking similarities to the Paleo diet and the Atkins diet. This practice usually means trying to eat a high-protein and low-carb diet, so say goodbye to pasta and potatoes. In fact, ketones are chemicals made from the fat that your body burns for fuel when there are no carbohydrates left to consume, as the Atlantic reports. The thinking is that if you keep to a strict diet, or take a ketone supplement, you can try and achieve a consistent state of ketosis, which some say can help you lose weight or boost athletic performance. Could it be a secret weapon in the fight against fat? If you are a runner or a bicyclist looking for an edge, or a dieter desperate to shed those unwanted pounds, that may sound too good to be true. The hope is that you can put some wow into your workout. One company set to release a ketone energy drink has dubbed it the “fourth food group.” Of course, the taste of such supplements may also be a factor. One game Atlantic writer described the flavor this way: “It tasted like cough syrup that had been poured into a garbage bag and left in the sun.” Research into the efficacy of ketones has been conflicting. A study conducted last year, as the New York Times reported, found that a ketone supplement seemed to improve the cycling performance of a group of 39 trained bike riders. It should be noted that this study, which was conducted by Oxford University, looked at moderate levels of exercise and not competition-level intensity, but it added fuel to the hope t Continue reading >>
Scientists Think They've Discovered A Fourth Type Of Fuel For Humans — Beyond Carbs, Fat, And Protein
Ketones could supercharge the body in a way unlike any other source of fuel. The San Francisco-based startup HVMN recently launched a drink made of pure ketone ester that it says can help people harness its performance-boosting qualities. The company partnered with Oxford University to leverage $60 million worth of scientific research with elite athletes. The nutrition label on a shot-size bottle of this clear, odorless liquid defies traditional explanation. It contains 120 calories — roughly the equivalent of a hearty slice of bread — yet it has no fat, no protein, and no carbohydrates. Those calories instead come from ketones, an ingredient that Geoff Woo, the cofounder and CEO of a San Francisco-based human-performance startup called HVMN (pronounced "human"), likes to call "the fourth macronutrient." "It's not a fat, it's not a protein, it's not a carb, but your body gets fuel from it," Woo told Business Insider. With that in mind, Woo launched his company's first ketone product, a 2.2-ounce bottle of ketone ester called Ketone. The drink, now available for preorder, promises improved athletic ability and energy, and a heightened sense of focus. To make the product, HVMN leveraged more than a decade and $60 million worth of scientific research through an exclusive partnership with Oxford University. Ketone could boost performance 'unlike anything we've ever seen' Most of the food we eat contains carbs. The carbs in fruit come from naturally occurring sugars; those in potatoes, veggies, and pasta come from starch. They're all ultimately broken down into sugar, or glucose, for energy. When robbed of carbs, the body turns to fat for fuel. In the process of digging into its fat stores, the body releases molecules called ketones. A high-fat, low-carb diet (also known Continue reading >>
Pruvit Keto Os Exogenous Ketones Review – Miracle Supplement?
Pruvit Keto//OS Ketone Operating System Review Hello! Hi, my name is Rachel Vrabel and you can find me on Instagram @womensblogtalk or on Facebook. Today I’m reviewing a supplement made by Prüvit called Keto//OS (Ketone Operating System), which is a powder you mix with water and drink once or twice daily that tastes delicious! Keto OS puts your body into a fat burning state of ketosis within 30 minutes by flooding your body with exogenous ketones. The skinny is – you’re burning FAT rather than carbs. Good for weight loss? Heck yes! And extremely safe. But what’s even more amazing is how you FEEL (remember that, because ketones are NOT just a fat loss aid, that’s just side effect of being in ketosis!) Remember the Atkins Diet – high fat, low carb? It’s a tough diet to follow, but one that works to shed weight quickly if you can endure the food restrictions. A similar diet is the Ketogenic Diet which is a high fat/moderate protein/low carb diet and there are plenty of restrictions. But what if you don’t want to follow a strict diet but you still want the benefits of being in ketosis? This is where Keto//OS sets itself apart from every other supplement on the market! Here are some of the benefits of ketosis and drinking Keto OS: Fat loss Sustained energy Increased focus Suppressed appetite Better mood Better sleep Muscle preservation Anti-aging, clearer skin Please, keep scrolling for information on each of the flavors! But first I’d like to tell you about my Pruvit Keto-OS Results! Check out my Youtube Video Review on Keto OS How Much Weight Have I Lost on Keto OS? Keto OS Before and After Photos – Results from Drinking Keto OS Round #1 (Jan. 2016) Ok so I’ve had two rounds with losing weight on Keto OS and I want to tell you about both times, becau Continue reading >>
- For the love of exogenous ketones!
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This Ketone Energy Drink Promises Superhuman Results—but Will It Work?
A start-up in San Francisco called HVMN has created a drink made of nothing but the ketone ester, and claims that drinking a shot-sized bottle of the stuff will do wonders for athletes' endurance, energy and focus. It's apparently so powerful, HVMN calls it "superfuel." It's “unlike anything we’ve ever seen before,” Kieran Clarke, Ph.D., professor of physiological biochemistry at Oxford University, told Business Insider. Clarke has studied ketones extensively, and has been assisting HVMN with their drink called HVMN Ketone. So what exactly are ketones? As we've reported in the past, they're compounds that your liver makes from your fat reserves when your blood insulin levels are low. “Your liver produces ketones all the time, but the rate depends on carbohydrate and protein intake,” Jeff Volek, Ph.D., R.D., a professor of human sciences at Ohio State University, told Men's Health earlier this year. If you aren't consuming enough carbs and protein, your body will make a ton of the stuff so that it still has fuel to function. HVMN is starting by marketing the ketone drink to athletes. It contains 120 calories and no fat, carbs, or protein. "It is, effectively, a fourth type of fuel for humans," as Business Insider put it. The Best Cup Of Coffee You Will Ever Make: This is a modal window. Beginning of dialog window. Escape will cancel and close the window. End of dialog window. HVMN's drink contains 120 calories and no fat, carbs, or protein. Before it was released to the public, Clarke tested it among elite cyclists for a study that was published in Cell Metabolism in 2016. The cyclists who were given HVMN Ketone outperformed two other groups who were given either a carb- or fat-based drink by an average of 400 meters. (The Metashred Extreme workout program from Continue reading >>
Pruvit Keto Os Review
We wanted to get to the bottom of things with Keto OS. Right off the bat there was an outpouring of negative reviews on taste, making our team jump straight into the ingredients. Then we noticed a rash of comments about side effects, which was enough to make us tackle the science head on. We took the information we found, summarized it, and now share with you – the truth about Keto OS. What is Keto OS? Pruvit Keto OS supplement is a powdered drink offering weight-loss support. If this drink is as terrible as some of the customer comments make it out to be, we have a hard time believing that anyone is seeing results. Before we get into the ingredients, according to the company itself, they can cause side effects. “Supplementing with KETO//OS or following a ketogenic diet can cause a slightly diuretic effect, and can deplete magnesium, potassium and sodium stores.” And that wasn’t all. Before we get ahead of ourselves, here are the Keto OS ingredients: MCT Powder Beta-Hydroxybutyrate Stevia Keto OS Max offers the same, but l-leucine, l-taurine, and a few others are added. Just one scoop or packet a day is supposed to force you into ketosis , so your body burns fat instead of carbs. This idea is what low-carb diets are based on. Ketosis is not to be confused with ketoacidosis, a medical condition that can be life-threatening. Pruvit, the makers of Keto OS, started online in 2013. You have various options to choose from on the official website including a canister of powder or prepackaged servings, which makes the Keto OS diet plan a bit easier. We like the addition of caffeine but that’s not the best part. Pruvit Keto OS Competitors Product Price Review Ketopia read Ketocana read Thrive Patch read Shakeology read Burn HD (Sample offer) read Other similar produ Continue reading >>
Scientists May Have Found A "fourth Fuel" That Can Power Humans
Food can be broken down into three macronutrients: fat, protein, and carbohydrates. Now, according to scientists at Oxford University and the National Institute of Health (NIH), there could be a "fourth macronutrient" called ketones. Ketones aren't anything new, but you won't find them naturally occurring in the food we eat. Instead, the substance is produced in the liver as part of a biological process to help us cope with starvation. If we don't have enough fuel from food, the body digs into its internal fat supplies, breaking it down into ketones. Normally, you have to reach starvation mode to produce ketones – a state that can be triggered by the ketogenic (or keto) diet, which involves a very strict low-carb meal plan and may include feelings of euphoria. Soon, however, this magical substance will be available commercially. A ketone drink is set to hit the market and will be sold by the San Francisco based start-up HVMN, apparently pronounced "human". The colorless liquid is zero-carb, zero-fat, and zero-protein, yet it packs in 120 calories. It is being sold as "a clinically validated superfuel" that will "improve training, recovery, and performance". But here's a warning: Even Geoff Woo, co-founder of HVMN, admitted it tastes like "a combination of a liquor shot with nail-polish remover" in an interview with The Atlantic. Plus, at $99 for three 2.2-ounce bottles, it probably isn't within most people's pay-packets. Does it work? Two writers at Business Insider tested the drink and reported improved focus, but they also admitted it was hard to tell if it was thanks to the ketone drink or simply a placebo effect. There is, however, some scientific research to back its claims. A 2016 study, published in the Journal Cell Metabolism, tested the effects of a ketone dr Continue reading >>
My Experience With Exogenous Ketones
Last year I wrote a couple of posts on the nuances and complexities of ketosis, with an emphasis on nutritional ketosis (but some discussion of other states of ketosis—starvation ketosis and diabetic ketoacidosis, or DKA). To understand this post, you’ll want to at least be familiar with the ideas in those posts, which can be found here and here. In the second of these posts I discuss the Delta G implications of the body using ketones (specifically, beta-hydroxybutyrate, or BHB, and acetoacetate, or AcAc) for ATP generation, instead of glucose and free fatty acid (FFA). At the time I wrote that post I was particularly (read: personally) interested in the Delta G arbitrage. Stated simply, per unit of carbon, utilization of BHB offers more ATP for the same amount of oxygen consumption (as corollary, generation of the same amount of ATP requires less oxygen consumption, when compared to glucose or FFA). I also concluded that post by discussing the possibility of testing this (theoretical) idea in a real person, with the help of exogenous (i.e., synthetic) ketones. I have seen this effect in (unpublished) data in world class athletes not on a ketogenic diet who have supplemented with exogenous ketones (more on that, below). Case after case showed a small, but significant increase in sub-threshold performance (as an example, efforts longer than about 4 minutes all-out). So I decided to find out for myself if ketones could, indeed, offer up the same amount of usable energy with less oxygen consumption. Some housekeeping issues before getting into it. This is a self-experiment, not real “data”—“N of 1” stuff is suggestive, but it prevents the use of nifty little things likes error bars and p-values. Please don’t over interpret these results. My reason for shari Continue reading >>
My Experience With Exogenous Ketones: Tale And Truth
97 Comments I woke up the morning of the ceremony with butterflies in my stomach. I’d done the necessary prep. I’d abstained from carbs the past week and food the past 24 hours. I’d performed four consecutive full-body circuit workouts to deplete muscle glycogen, and undergone a liver biopsy to confirm full depletion of liver glycogen. I wasn’t taking any chances. Although I had extensive experience generating endogenous ketones and subsisting on my own body fat, exogenous ketones were another matter entirely. You don’t want to mess around with a holy sacrament without doing due diligence. Holy sacrament? Yes. According to ethnographic accounts from early Arctic explorers who encountered the sacred compound, the exogenous ketone was developed by traditional peoples of the wintry north. No one’s quite sure where it arose first—Siberia, Greenland, Alaska, Lapland. What they do know is that these societies revered the type 1 diabetic, a rare find in the pre-contact Arctic. Using an admittedly grisly and cruel process, these groups would starve the tribe’s diabetic to induce ketoacidosis, harvest the ketone-rich urine, and reduce it slowly to a ketone-rich tar over a wood fire. Tribe shamans would dissolve the tar in pine needle tea and distribute it to members exclusively before hunting trips, warfare, and any other activity requiring optimal physical and mental function to boost energy and improve performance. As Mark Twain famously quipped, “The strongest coffee I ever had was a Laplander’s piss.” So when I showed up to the small building on the edge of town on a rainy evening, I was anxious. What was I in for? The solemn countenances worn by my two guides for the day—Dr. Peter Attia, wearing dark robes and swinging a thurible loaded with burning Continue reading >>
This New Energy Drink Promises To Turn You Into A Superhuman
San Francisco-based start-up HVMN (pronounced “human”) has developed a drink made of pure ketone ester – a supplement that some scientists are calling the fourth type of fuel, alongside carbs, fat and protein. Ketone is a shot-sized bottle of clear liquid that contains 120 calories. HVMN promises the drink will improve your energy and focus. “It’s not a fat, it’s not a protein, it’s not a carb, but your body gets fuel from it,” Geoff Woo, the company’s co-founder and CEO told Business Insider. The human body releases chemicals called ketones when it runs out of carbohydrates for energy and is forced to tap into fat reserves. This is the basis of the ketogenic diet, which relies on high-fat, no-carb meals. Essentially, cutting carbs from our diets releases ketones that turn our bodies into a fat-melting machine. But the ketogenic diet is hard to sustain since it’s extremely difficult to completely cut out carbs. Enter Ketone, which lets you directly ingest the ketones without tricking your body into starvation-mode. The fuel is “unlike anything we’ve ever seen before,” Kieran Clarke, a professor of physiological biochemistry at Oxford University, who studies ketones and has been working in partnership with HVMN, told Business Insider. When Ketone was given to a group of elite cyclists – some of whom were former Olympians — they traveled an average of 400 meters further than cyclists who’d been given a carb-rich or fat-rich energy drink. Those findings were published by Clarke and her colleagues in Cell Metabolism in July 2016. However a more recent study found that, after giving a ketones-based drink to 11 elite cyclists in Australia, the athletes performed worse, had slower times and all reported upset stomachs. One couldn’t even start Continue reading >>
Let’s Talk About Ketones, Ketosis + Ketogenic Diets.
Okay, I know this is the question of the century right now on my blog and social media and now PODCAST because I have been sharing a ton about the Keto OS Bio Max product that I am d.y.i.ng over (organically, BTW, just genuinely dying over it): WHAT ARE KETONES?! What the heckkkkk is ketosis? What are the health benefits, and why / how is this good for us? EPISODE HERE // Well guys, today we debunked it all on The Balanced Blonde Podcast, Episode 14– a BONUS episode this week because I was so freaking stoked to share the details of ketosis with you. I decided to have my nutritionist Kelly Leveque (you guys should know her as a household name by now if you read my blog frequently — she is my go-to for literally everything nutrition + science + geeky — hehe, love you Kell) & celeb personal trainer / total keto expert Wes Okerson as my guests so that we could answer ALL of the q’s I have been getting from you guys and also the questions I’ve had myself about the process of ketones in the bod! Listen to the episode here & let us know your thoughts + any q’s!!! First, let’s get something straight: WHAT IS KETOSIS? Ketosis, by definition, is a metabolic state characterized by raised levels of ketones in the body. The “keto” in the word ketosis comes from the fact that it makes the body produce small fuel molecules called ketones. This is an alternative fuel for the body, used when blood sugar (glucose) is in short supply. It is hard to get the body into ketosis through diet alone (although it can be done — it requires a super low-bard diet that is very hard and basically unnecessary for most of us to stick to longterm), but this insanely awesome Keto OS powder that the three of us use gets the body into ketosis within 90 minutes of drinking this powder in Continue reading >>
On The Metabolism Of Exogenous Ketones In Humans.
Abstract Background and aims: Currently there is considerable interest in ketone metabolism owing to recently reported benefits of ketosis for human health. Traditionally, ketosis has been achieved by following a high-fat, low-carbohydrate "ketogenic" diet, but adherence to such diets can be difficult. An alternative way to increase blood D-β-hydroxybutyrate (D-βHB) concentrations is ketone drinks, but the metabolic effects of exogenous ketones are relatively unknown. Here, healthy human volunteers took part in three randomized metabolic studies of drinks containing a ketone ester (KE); (R)-3-hydroxybutyl (R)-3-hydroxybutyrate, or ketone salts (KS); sodium plus potassium βHB. Methods and Results: In the first study, 15 participants consumed KE or KS drinks that delivered ~12 or ~24 g of βHB. Both drinks elevated blood D-βHB concentrations (D-βHB Cmax: KE 2.8 mM, KS 1.0 mM, P < 0.001), which returned to baseline within 3-4 h. KS drinks were found to contain 50% of the L-βHB isoform, which remained elevated in blood for over 8 h, but was not detectable after 24 h. Urinary excretion of both D-βHB and L-βHB was <1.5% of the total βHB ingested and was in proportion to the blood AUC. D-βHB, but not L-βHB, was slowly converted to breath acetone. The KE drink decreased blood pH by 0.10 and the KS drink increased urinary pH from 5.7 to 8.5. In the second study, the effect of a meal before a KE drink on blood D-βHB concentrations was determined in 16 participants. Food lowered blood D-βHB Cmax by 33% (Fed 2.2 mM, Fasted 3.3 mM, P < 0.001), but did not alter acetoacetate or breath acetone concentrations. All ketone drinks lowered blood glucose, free fatty acid and triglyceride concentrations, and had similar effects on blood electrolytes, which remained normal. In th Continue reading >>
The Ketogenic Diet Now Comes In A Tiny Bottle, But Dietitians Are Skeptical
HVMN Don’t want to fast to try the ultra-trendy, high-fat, low-carb ketogenic diet? A San Francisco startup thinks you should take a shot of its elixir instead — even though the science behind it is dubious, experts say. The supplement company HVMN (that’s Silicon Valley-shorthand for “human”) unveiled its newest product on Monday: HVMN Ketone, a 2.3-ounce vial of a substance called ketone ester. It’s supposed to almost immediately put you in ketosis, a metabolic state where the body is forced to burn fats instead of carbohydrates. By loading the body with “an ultra-efficient form of fuel,” as the company says, it’s supposed to help you perform better in workouts and think more clearly. But even though HVMN says the drink is “proven to improve athletic performance and recovery,” nutrition experts say it is highly unlikely that a ketone supplement can single-handedly put you in ketosis. They also say there is little evidence that being in ketosis helps athletes. The public won’t get its first taste of it until next month. But registered dietitian Ben Sit is skeptical. “I have not yet found one ketone ester supplement that has been able to successfully put someone into the state of ketosis, no matter what dosage they take,” Sit, president of Evolved Sport and Nutrition, told BuzzFeed News. HVMN, formerly known as Nootrobox, is among a handful of consumer product startups that bill themselves as part of the loosely defined biohacking movement. Backed by tech venture capitalists, these companies, which include Bulletproof Coffee and Soylent, hawk food and supplements to busy, health-conscious people who have a quantify-everything mindset. HVMN, which raised $2 million in 2015 from Andreessen Horowitz (also a BuzzFeed investor), is best-known for Continue reading >>