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Ketone Bodies Starvation

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Ketone Bodies Metabolism

1. Metabolism of ketone bodies Gandham.Rajeev Email:[email protected] 2. • Carbohydrates are essential for the metabolism of fat or FAT is burned under the fire of carbohydrates. • Acetyl CoA formed from fatty acids can enter & get oxidized in TCA cycle only when carbohydrates are available. • During starvation & diabetes mellitus, acetyl CoA takes the alternate route of formation of ketone bodies. 3. • Acetone, acetoacetate & β-hydroxybutyrate (or 3-hydroxybutyrate) are known as ketone bodies • β-hydroxybutyrate does not possess a keto (C=O) group. • Acetone & acetoacetate are true ketone bodies. • Ketone bodies are water-soluble & energy yielding. • Acetone, it cannot be metabolized 4. CH3 – C – CH3 O Acetone CH3 – C – CH2 – COO- O Acetoacetate CH3 – CH – CH2 – COO- OH I β-Hydroxybutyrate 5. • Acetoacetate is the primary ketone body. • β-hydroxybutyrate & acetone are secondary ketone bodies. • Site: • Synthesized exclusively by the liver mitochondria. • The enzymes are located in mitochondrial matrix. • Precursor: • Acetyl CoA, formed by oxidation of fatty acids, pyruvate or some amino acids 6. • Ketone body biosynthesis Continue reading >>

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Popular Questions

  1. dt2

    I think my diet has too much protein. making keto breath worse..

    I think I had Ketoacidosis at one point a while back.. and i'm doing better with that..
    I try to follow a lchf diet and yes, it keeps my bg low.. but I think I'm not doing it right..
    I am single and I don't cook much.. so I've been eating out .. denny's.. or a stake out.. or some wings from wingstop..
    I think everything is Eggs, Bacon, Sausage, Steak, Cheese, Chicken .. yea.. that's about it.. so yea all that is low carb, but there's not much green in there.. oh, green beens with my steak(s)..
    and I really felt like my keto breath wasn't getting better , it was getting worse.. so I read that to much protein can also cause bad breath.. maybe that's my problem.. I need more salads with some of the green stuff.. I found some stuff on this page.. http://thepaleodiet.com/bad-breath-b.../#.Vhrv-2sca0U .. yes, I know this is a little bit different diet, but I'm focusing on the added greens/vegetables it talks about
    it has caused me some distress.. I've had a couple times where I basically relapsed.. just being upset about my breath and the problems it has caused me.. not to mention, it's not easy to not have some of the things that I've eaten before.. the biscuits, pancakes, etc.. I'm trying.. but it's a struggle..
    When I felt like I was doing good on the diet, I think my breath was getting worse.. so I'm reevaluating some changes to make..

  2. furball64801

    I am doubting you were in DKA you might have been in ketosis which is another thing. They really are two different things. If you are not adding fat into the diet it should be that does help.

  3. dt2

    Originally Posted by furball64801
    I am doubting you were in DKA you might have been in ketosis which is another thing. They really are two different things. If you are not adding fat into the diet it should be that does help. ok.. I don't know if I was in DKA .. but this was a few months ago.. my a1c was over 15.. It was really before I started taking my diabetes seriously.. my nurse at the VA , she said that was the cause of my bad breath.. so I started working on it.. and after some more time ultimately ended up trying the lchf diet..
    I've done alot of reading.. got some keto stick to see when I go into ketosis.. etc.. I don't think I'm doing good for long periods of time.. I do good for a few days.. maybe 10 days at one point.. but I get upset because of the problems with my breath.. and if I relapse, I'm sure it kicks me out of ketosis ..

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