
Fat Contributes To Insulin Resistance
So, while discussing LCHF with my doc this publication was referred to - This claims that insulin is required to metabolize Carbs, protein AND fat. Wait, what? If this is true, then eating a diet high in fat is not the solution for insulin resistance. IF could be, because that minimizes the amount of time your body is producing insulin. But merely cutting out carbs, and not eating too much protein, will not reduce insulin resistance on its own. Excellent question. I believe @erdoke or @richard can provide a much more detailed description than I can, but I will say that Insulin is involved. Im not sure that your conclusions comment is correct, but they should be able to help you when they get back online later. Do you have a link to the full text of the study? It is difficult to determine whether they were studying type-1 or type-2 diabetics and whether or not any of the subjects were on ketogenic diets. Also, one of the problems with insulin resistance is that fat cells stop being able to absorb fat from the bloodstream. Basically, anything you eat has the ability to raise insulin. Stress also has this ability. But since you have to eat something to survive, the goal is to eat the least insulinogenic foods possible. Marty Kendall has an excellent summary of this here: Make your own mind up on what they may sell Yup. Research is often fiscally driven too. It is important also to read the study to see where the funding comes from. There is loads of political/financial bias in research. Its not enough to glance at a study. You must read the nitty gritty and do research about the researchers! oh look the head of this IDC is trying to sell tech which simply pumps insulin into people. Now this is referred to for T1 but bet they like to sell insulin to t2 eh ? Insulin is not Continue reading >>

Ketogenic Diet Improves Insulin Sensitivity And Numerous Aging Markers
A physician conducted a decade-long experiment on the health effects of a ketogenic diet, using himself as the laboratory rat; he experienced improvement in insulin sensitivity, body fat, lipids, blood sugar, and other markers A ketogenic diet requires carbohydrate and protein restriction, with 50 to 80 percent of calories coming from fats; this forces your body to shift toward using ketones as its primary fuel source, instead of glucose Although your brain is more dependent on glucose than your heart, your liver can produce a ketone-like compound that your brain can efficiently use for energy Scientists extended the lifespan of mice by 20 percent by suppressing the activity of just one gene that helps control metabolism and energy balance; this is further evidence that longevity is tied to insulin signaling The best way to jumpstart your fat-burning/ketone-producing engine is by drastically reducing your consumption of sugar and grains, fasting intermittently, and maintaining a consistent exercise routine By Dr. Mercola We are just beginning to understand the biological intricacies of aging. A growing body of research is challenging the belief that aging is beyond your control, prompting scientists to begin thinking about ways we can slow our aging clocks to a slow crawl. Although this is a relatively new branch of science, there are some factors that appear to be key in controlling how quickly you age. One major factor seems to be insulin signaling and the metabolic "engines" you have running day to day, which are largely controlled by the foods you eat. In the first featured video, Dr. Peter Attia discusses how a ketogenic diet can optimize your metabolism. But before I discuss the specifics of this, I want to tell you about a remarkable mouse study, presented in the Continue reading >>

The Ketogenic Diet And Insulin Resistance
We recently touched on how you can use the ketogenic diet to control symptoms of diabetes such as elevated glucose and triglycerides. In this article, we examine research showing the impact that the ketogenic diet has on levels of the hormone insulin, a key regulator of blood sugar in the body. What is Insulin’s Role in the Body? Before we look at the research, we need to know our main players. Insulin is a protein-based hormone produced by beta-cells located in the pancreas. The pancreas, which is located under the stomach, also produces enzymes that aid with digestion. Insulin’s primary purpose is to regulate the metabolism of fats and carbohydrates. The digestive system breaks down carbohydrates, such as sugars and starches, into a molecule called glucose. This compound can be used by cells to produce energy through a process called cellular respiration. Insulin allows cells in the body absorb glucose, ultimately lowering levels of glucose in the blood stream. After a meal is consumed, blood glucose levels increase and the pancreas responds by releasing insulin into the blood. Insulin assists fat, liver, and muscle cells absorb glucose from the blood, resulting in lower levels of blood glucose. Insulin stimulates liver and muscle tissues to store excess glucose as a molecule called glycogen and also reduces glucose production by the liver. When blood sugar is low, the hormone glucagon (produced by alpha-cells in the pancreas) stimulate cells to break down glycogen into glucose that is subsequently released into the blood stream. In healthy people who do not have type II diabetes, these functions allow levels of blood glucose and insulin to stay in a normal range. What Is Insulin Resistance and Why Is It a Problem? Unfortunately, for many Americans and other peopl Continue reading >>

Ketogenic Diet And Insulin Resistance
Insulin is a fat storing blood sugar regulating master hormone that is involved in multiple body functions beyond its metabolic role. A few examples include triglyceride and fat synthesis, electrolyte balance of sodium and potassium, feeding behaviors and cognitive and emotional brain function. Insulin resistance(IR),might also known as syndrome X or metabolic syndrome, is a cluster of symptoms (weight gain, cravings and increased appetite, skin tags, gum disease, low energy) and health risk factors (abnormal, not necessarily high, blood sugar, high triglycerides and cholesterol, polycystic ovarian syndrome, high blood pressure) all resulting from abnormal insulin function. What is important to know is that just like diabetes, with IR there may be no symptoms at all. Insulin resistance is anearly-stage in Type 2 diabetes but not everyone with IR will develop diabetes. Fifty percentof those with essential hypertension areinsulinresistant. ( 1 ). How Many People Are Affected by Insulin Resistance? IR is more common than you think, in the United States, an estimated 60 to 70 million individuals are affected by insulin resistance, thats 1 out of 4 people. More than 40% of individuals older than 50 years may be at risk for insulin resistance; however, it can affect anyone at any age ( 2 )especially overweight children and adolescents regardless of race. You can connect with this link to see a table of the prevalence of insulin resistance by country . There are several causes of insulin resistance: Genetics and family history of diabetes, pre-diabetes Ethnic origin (African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, or Pacific Islander American) Am I at Risk of Developing Insulin Resistance? Insulin resistance or prediabetes is characterized w Continue reading >>

Does Long Term Ketosis Cause Insulin Resistance?
“It’s a snake.” “It’s a wall.” “It’s a rope.” “It’s a fan.” “It’s a tree.” “It’s insulin resistance.” I’ve always been fascinated by those describing a “new finding” in medicine. I am reminded of the story of 5 men who, never having seen an elephant before, were blindfolded and asked to describe what he discovered. However, each man was introduced to a different part of the elephant. Each of them had a dramatically different description of the elephant and each made a conclusion that was very different from the others. What is fascinating, is that we usually make our “blindfolded comparisons” to those things we have seen or about which we have some descriptive understanding. Observing and describing human physiology is much like examining an elephant while blindfolded for the first time. This week’s “blind-folded finding” is what has been interpreted by some as “insulin resistance” made worse by a ketogenic diet. Really? This perked my curiosity, because I’ve personally been following a low-carbohydrate/ketogenic diet for 10 years and have thousands of patients doing the same. To this day, I’ve never seen insulin resistance “get worse.” In fact, it gets better. Clinically, it seems to take about 18-24 months to improve, but, it usually gets better. THE QUESTION – I’ve had three people from around the world contact me this week and ask why, after being on a ketogenic diet and “in ketosis,” they suddenly get a notably large blood glucose spike when they cheat. By notably large, I mean that their blood sugars rise to over 200 mg/dl within 2 hours of a carbohydrate containing meal. Now, they admit to rapid glucose recovery within an hour or two, and their hemoglobin A1c levels are subjectively normal (l Continue reading >>

Insulin Sensitivity: The Secret To Optimal Health
Insulin Sensitivity: The Secret to Optimal Health Insulin sensitivity is a vital mechanism in your body that determines how efficient your body utilizes the effects of insulin. People with low insulin sensitivity have a higher chance of developing metabolic diseases such as diabetes, obesity and heart disease. While some people may be born with healthier insulin sensitivity levels, there are several lifestyle changes you can make to improve it. The more insulin sensitive your body is, the more effective it is in utilizing carbohydrates for energy and the easier it becomes for your body to lose weight. Because of this, the weight loss industry has begun to magnify the importance of insulin sensitivity. Insulin is a crucial hormone secreted by your pancreas. Insulins job is to manage the nutrients you absorb from food. Insulin is known for its role in controlling blood sugar and carbohydrate consumption. When you eat carbs, it increases the level of blood sugar in your bloodstream. This is acknowledged by the cells in your pancreas which then releases insulin into the blood. Once the insulin is traveling in your bloodstream, it starts signaling the bodys cells that they should pick up sugar from the blood. The purpose of this cycle is to reduce the amount of sugar in your blood and place it where its supposed to, into cells for storage. This is crucial because abnormally high amounts of sugar in your blood can have harmful effects to your body and in some cases can lead to death if neglected. Insulin sensitivity is a system in the body that determines how effectively your body can utilize carbohydrates. Insulin sensitivity arbitrates how much insulin your body needs to produce to precipitate a certain amount of glucose (sugar). Its the mechanism in your body that determi Continue reading >>

Ketogenic Diet And Insulin Resistance
Ketogenic diets around the world have been known to be extremely effective in helping improve health and lose weight fast. The diet takes into account and addresses the underlying causes of your weight gain, which could include things such as hormonal imbalances. With the ketogenic diet, you are restricting your net carb intake to under 50 grams a day. With the number of restricted carbs, your body needs to reset its way of getting the fuel that it needs. See how a diet high in healthy fats can help improve insulin resistance by changing the bodies preferred fuel source from glucose to ketones. What is Insulin and Insulin Resistance Insulin is a fat storing hormone formed by the pancreas that enables your body to manage glucose and sugars from carbs within the food. It prevents blood sugar levels from hyperglycemia or reaching too high or hyperglycemia which is too low. Insulin resistance has many symptoms including sugar cravings, weight gain, high blood pressure, high cholesterol.(1) Insulin resistance is also linked to type 2 diabetes. Therefore, cutting out or reducing sugar in your meal planning will help prevent becoming diabetic. The worrying thing about insulin resistance is symptoms take a long time to appear. When symptoms surface such as weight gain, multiple other problems may creep up. Why You Gain Weight Insulin in your body helps to regulate your blood sugar levels. Blood sugar also referred to as glucose is the primary fuel in the body for energy and brain function. When blood sugar rises, the insulin your pancreas releases move the glucose into your bloodstream. If there is glucose in your system your body will burn it first for fuel. If your body is already filled with higher glucose levels, more cannot be broken down for fuel. So because of this, your Continue reading >>

Insulin Sensitivity And Glucose Tolerance Are Altered By Maintenance On A Ketogenic Diet
The ketogenic diet (KD) is a low-carbohydrate, high-fat diet that is used for a variety of health-related effects. This type of diet is effective at suppressing seizure activity in children with refractory epilepsy (1) and has perhaps more commonly been implemented as a dietary strategy by which weight maintenance or weight loss is the desired outcome. It has been demonstrated that restriction of dietary carbohydrates results in positive effects on cardiovascular parameters. Consuming this type of diet favorably affects body adiposity and improves features of metabolic syndrome in humans (2,3,4,5,6). Although studies evaluating the efficacy and metabolic effects of KDs have increased in recent years, the effects of macronutrient-controlled diets remain controversial in the literature. Insulin has potent short-term and long-term effects on energy intake and glucose homeostasis. In the short term, insulin release is cephalic; the brain initiates insulin secretion by directing messages through the vagus nerves to the pancreas as opposed to direct pancreatic stimulation of insulin-secreting cells. Cephalic insulin is most readily observed at the onset of a meal and consists of a short burst of insulin that is preabsorptive with regard to the ingested food. After consumption of a meal, insulin secretion increases and is sustained, because one of insulin’s roles is to prepare the body for the increase in glucose that accompanies food intake and to control the increased levels and use of glucose (7). In the long term, insulin’s role as an adiposity signal is well known, with increased plasma insulin levels resulting from increased body weight. Together, the short- and long-term effects of insulin allow for proper glucose homeostasis and assist in the regulation of body wei Continue reading >>
- Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis
- Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis
- The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus

Ketosis And The Ketogenic Diet: Debunking 7 Misleading Statements
Ketosis and the Ketogenic Diet: Debunking 7 Misleading Statements The ketogenic diet is the most popular dietary trend in our world today. Especially for those living with diabetes, its likely that youve been tempted to follow a ketogenic diet to lose weight, drop your A1c, and flatline your blood glucose. Even though it may seem tempting to enter the metabolic state of ketosis, its important to understand the caveats of ketosis, so that you fully understand your risks for developing long-term complications. So what exactly is a ketogenic diet? And why is ketosis a popular recommendation for those living with diabetes? A ketogenic diet a very low-carbohydrate diet by design, containing a maximum of 30 grams of dietary carbohydrate per day. When eating a ketogenic diet, you are told to avoid carbohydrate-rich foods like fruits, starchy vegetables, legumes, and whole grains, and instead eat larger quantities of meat, dairy, leafy greens, non-starchy vegetables, nuts, seeds, and vegetable oils. At the base of the ketogenic food pyramid are eggs, dairy, meat, oil, and fish, which make up the bulk of calories eaten. Non-starchy vegetables contain too much carbohydrate energy and are avoided, while non-starchy vegetables or green vegetables are included, along with nuts, seeds, and very limited amounts of fruit (mainly berries). In order to achieve the state of ketosis, you are only allowed to eat a small amount of carbohydrate energy from fruits and starchy vegetables. The ketogenic diet explicitly prohibits the consumption of grain products (even whole grains), pasta, refined sugar, milk, corn, legumes (including lentils, beans, and peas), as well as rice. When you eat a ketogenic diet, your muscle and liver switch from oxidizing glucose as their primary fuel to fatty acid Continue reading >>

The Pathways Of Insulin Resistance
2,744 views Are we chasing the wrong guy when it comes to heart disease? And if so, what is the real culprit in the disease? Ivor Cummins gives an alternative way to look at heart disease and the connection to insulin resistance. Watch a part of the presentation above (transcript). The full video is available (with captions and transcript) with a free trial or membership: The Pathways of Insulin Resistance – Ivor Cummins Join free for a month to get instant access to this and hundreds of other low-carb TV videos. Plus Q&A with experts and our awesome low-carb meal-plan service. Top videos about insulin Top videos about heart disease Continue reading >>

Are You Insulin Resistant?
Finding out you are insulin resistant doesn't mean much unless you understand what that implies, and how it effects your health. Insulin resistance is an condition in which the body is not responding properly to the hormone insulin. If faulty insulin signaling is not treated, it can develop into worsening conditions of metabolic syndrome, pre diabetes, and finally type 2 diabetes. What Causes the Insulin Resistant Condition? The insulin resistant condition is rooted in the metabolic effects of a high carb diet in combination with a lack of exercise. Weight gain is a symptom of insulin resistance, rather than a cause. Carbohydrates are foods which contain either some form of sugar or starch, or both. For instance, orange juice is full of fructose, a type of sugar, and white potatoes contain large amounts of starch. Both types of carbohydrate are broken down in the body into glucose, a simple sugar, which your cells can use for energy to do all the things that cells do. Since too much glucose in your body can be toxic, your pancreas releases a powerful hormone called insulin. Insulin works to control the amount of glucose in your bloodstream. It acts to quickly move glucose from your bloodstream and push it into your cells where it can be burned or stored. But there's a catch. To get the glucose into the cells, the cell's glucose "storage tanks" have to be empty. This is logical when you think about it. Imagine what would happen if you tried to fill up your car's gas tank if it were already full. And just like running a car burns up gasoline, when a person exercises, the glucose which is already in the glucose tanks get used. Now there is room for insulin to push the glucose made from the last meal into the muscle cell for fuel. If a person exercises frequently, lots of c Continue reading >>

008: Boosting Insulin Sensitivity And Workout Performance With A Ketogenic Diet Rachel Gregory And Dr. Brian Lenzkes
Is it by your weight, your blood pressure, your cholesterol profile, or maybe all of them? According to Dr. Brian Lenzkes, theres one critical health marker you should pay attention to (but probably dont): insulin sensitivity. Dr. Lenzkes is an internal medicine doctor who focuses on clinical nutrition and helps his patients through lifestyle and nutrition changes. He also happens to be one of todays guests. Brian believes mainstream nutrition advice has made people so worried about fat and cholesterol that they dont pay attention to the damage carbs do to their body. Insulin resistance what happens when you lose insulin sensitivity is a direct result of eating too many carbs and too many meals per day, and its a precursor for diabetes and heart disease. However, most people dont know they have it until its too late. The CDC director admits that over a third of U.S. adults have prediabetes (which involves insulin resistance), and most of them haveno idea. The worst part is, by the time youre insulin resistant, its harder to turn your metabolism back to normal. Today Dr. Lenzkes explains why insulin sensitivity matters and how you can optimize yours with a ketogenic diet or a low carb approach. Todays episode is extra special because we have a double feature! Rachel Gregory is also my guest and she will explain how a ketogenic diet can give you an edge at the gym and radically improve your post-workout recovery. Rachel is a board-certified nutrition specialist and athletic trainer. She made a giant contribution to the scientific community and keto space by publishing the first ever human clinical trial about the effects of the ketogenic diet on CrossFit athletes. Shes seen first hand the positive effects a low carb diet has over metabolic flexibility. Lets just say that Continue reading >>
- The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus
- Nine-year-old boy with type 1 diabetes comes off insulin by eating Paleolithic ketogenic diet
- Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis

Fat Is Not The Cause Of Insulin Resistance
Fat Is NOT the Cause of Insulin Resistance Our Educational Content is Not Meant or Intended for Medical Advice or Treatment Fat is NOT the Cause of Insulin Resistance There isn't a relationship between eating saturated fats and diabetes. Insulin is a hormone that regulates blood sugars and lowers it. In the presence of insulin, you are not going to burn fat and it causes fat to be stored. Insulin resistance is different. As insulin connects to the cell, the cell does not absorb it anymore it blocks it. On the other side of the cell you have low insulin and the cell is starving of: Which then sends a signal back to produce more insulin. People with insulin resistance have 5 to 7 times more insulin than normal people. So many people have insulin resistance and dont even know it because it takes 10 years for it to develop it. It causes a stubborn belly fat and a fatty liver which cause insulin resistance. It's a huge ugly cycle. Guru's Give False Information About Diabetes There are gurus out there pushing this avoidance of saturated fats. Joslin Diabetes Center have 5 Myths on a section of their website that are bogus information.Some of the things they write as "Myths" are actualy true and what they report as "Facts" are way off. The following is from Joslin Diabete Center website under 'Diabetes and Nutrition': 5 Common Myths with People with Diabetes Debunked 1. People with diabetes have to eat different from their family, right? (Myth) "Fact: People with diabetes can eat the same foods their family eat. The Truth: Of course people with diabetes have to eat differently than their family. What if the family are eating sugar? 2. People with diabetes should never give in to food cravings. (Myth) Facts: If a craving does occur let yourself have a small taste of whatever y Continue reading >>

Insulin And Keto: What You Need To Know
If you want to make keto really work for you, it helps to understand a little bit about how the diet does its magic and one of the big players here is the hormone insulin. Insulin does a whole lot of different things, but its best-known as the hormone that you make to metabolize carbs. Insulin gets a really bad rap in low-carb circles, to the point where it can get really oversimplified. Theres more to weight gain than insulin! For general health, insulin isnt necessarily bad , and its actually necessary for some health-related goals (for example, if you want to gain muscle, insulin is definitely your friend). But keto isnt just about general health. Keto is about a specific metabolic shift. If your goal is ketosis specifically, insulin is bad news heres what you need to know. The whole point of the ketogenic diet is that youre forcing your body to use ketone bodies for energy, instead of fat and carbohydrate. Thats what makes the diet work. Insulin suppresses ketone production . So if you want to get into ketosis and stay there, you want to minimize insulin as much as possible. Unless youre taking outside insulin, the easiest way to do this is by changing what you eat. Insulin is produced in response to different foods, so by changing your diet, you can minimize insulin production. Thats the point of a ketogenic diet. The ketogenic diet minimizes insulin production by restricting both carbs and protein the diet keeps carbs as low as possible and supplies just enough protein to meet your needs, but not more. To reduce insulin production, lower carbs Carbs raise insulin levels because you need insulin to metabolize carbs (use them for energy). The more carbs you eat, the more insulin you need. It works like this: when you eat something carb-heavy, the glucose (carbohydr Continue reading >>

Dear Mark: Does Eating A Low Carb Diet Cause Insulin Resistance?
157 Comments Despite all the success you might have had with the Primal way of life, doubts can still nag at you. Maybe it’s something you read, or something someone said to you, or a disapproving glance or offhand comment from a person you otherwise respect, but it’s pretty common when you’re doing something, like giving up grains, avoiding processed food, or eating animal fat, that challenges deeply-and-widely held beliefs about health and wellness. It doesn’t really even matter that you’re losing weight or seem to be thriving; you may still have questions. That’s healthy and smart, and it’s totally natural. A question I’ve been getting of late is the effect of reducing carb intake on insulin sensitivity. It’s often bandied about that going low carb is good for folks with insulin resistance, but it’s also said that low carb can worsen insulin resistance. Are both true and, if so, how do they all jibe together? That’s what the reader was wondering with this week’s question: Hi Mark, I’ve been Primal for a few months now and love it. Lowering my carbs and upping my animal fat helped me lose weight and gain tons of energy (not too shabby for a middle-aged guy!). However, I’m a little worried. I’ve heard that low carb diets can increase insulin resistance. Even though I’ve done well and feel great, should I be worried about insulin resistance? Do I need to increase my carb intake? I always thought low carb Primal was supposed to improve insulin function. Vince Going Primal usually does improve insulin sensitivity, both directly and in a roundabout way. It improves directly because you lose weight, you reduce your intake of inflammatory foods, you lower systemic inflammation (by getting some sun, smart exercise, omega-3s, and reducing or dea Continue reading >>