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Keto Acidosis

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Alcoholic Ketoacidosis

Alcoholic ketoacidosis is a metabolic complication of alcohol use and starvation characterized by hyperketonemia and anion gap metabolic acidosis without significant hyperglycemia. Alcoholic ketoacidosis causes nausea, vomiting, and abdominal pain. Diagnosis is by history and findings of ketoacidosis without hyperglycemia. Treatment is IV saline solution and dextrose infusion. Alcoholic ketoacidosis is attributed to the combined effects of alcohol and starvation on glucose metabolism. Alcohol diminishes hepatic gluconeogenesis and leads to decreased insulin secretion, increased lipolysis, impaired fatty acid oxidation, and subsequent ketogenesis, causing an elevated anion gap metabolic acidosis. Counter-regulatory hormones are increased and may further inhibit insulin secretion. Plasma glucose levels are usually low or normal, but mild hyperglycemia sometimes occurs. Diagnosis requires a high index of suspicion; similar symptoms in an alcoholic patient may result from acute pancreatitis, methanol or ethylene glycol poisoning, or diabetic ketoacidosis (DKA). In patients suspected of having alcoholic ketoacidosis, serum electrolytes (including magnesium), BUN and creatinine, glucose, Continue reading >>

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Popular Questions

  1. Natalia & Enana

    Hi.
    I just put my cat in a veterinary emergency clinic with high ketoacidosis. They gave her an IV and insulin and other things I could afford. They told me to keep her there for 48 hours but I'm picking her up tomorrow and taking her to her vet. I dont know if my beautiful cat will survive. What are her chances? What are your suggestions.
    Thanks,
    Nat

  2. Sue and Oliver (GA)

    I am so sorry your kitty has DKA, Nat. It is possible to turn it around and she is in the best place to have that happen. We do have many cats who have survived and come home and lived long lives.
    What you can do - learn how to keep her safe at home. The best way to do that is to home test for blood glucose and for ketones. We test our cat's blood glucose levels just like we would our diabetic children. Here is a good site for beginning info: Newbie hometesting site and a video: Video for hometesting We have taught hundreds of people how to test over the internet. We would love to teach you. Testing for ketones will help you determine before DKA that he is heading into dangerous territory: ketones
    You can get the supplies for both these kinds of testing at any drug store. We use human glucometers and ketostix.
    Read about the best diet for your cat here: http://www.catinfo.org We feed wet lo carb food. BUT don't change the diet until you are hometesting. Oliver went down 100 points overnight when we switched from dry to wet. If we hadn't been hometesting, he would have overdosed.
    I am giving you a lot of info at once. The board is going down in 25 minutes and will be off for 2 hours for maintenance. Come back on later tonight or in the morning and post specifically for DKA. People who have dealt with it can give you lots of tips on how to care for your kitty when she gets home.

  3. Robert and Echo

    Nat, sending best wishes for your cat. Please keep us updated on her condition. Many cats do recover from DKA but, as you already know, it can be expensive treatment.
    _Rebecca

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