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Is Lactic Acidosis?

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Relief from severe depression and suicidal ideation within hours: from synapses to symptoms Air date: Wednesday, November 04, 2015, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 01:04:09 Description: NIH Director's Wednesday Afternoon Lecture Series Dr. Zarate's current research focus is on developing novel medications for treatment-resistant depression and bipolar disorder. His areas of expertise include biological and pharmacological aspects of mood disorders in adults. Dr. Zarate's group conducts proof-of-concept studies utilizing novel compounds and biomarkers (magnetoencephalography [MEG] and polysomnography [PSG], positron emission tomography, functional MRI and magnetic resonance spectroscopy [MRS]) to identify potentially relevant drug targets and biosignatures of treatment response. A multidisciplinary translational research team conducts the research in the ETPB. In addition, the Branch provides training to develop the next generation of clinical translational researchers. The Astute Clinician Lecture Series:The Astute Clinician Lecture was established through a gift from the late Dr. Robert W. Miller and his wife, Haruko. It honors a US clinician-scientist who has observed an unusual clinical occurrence, and by investigating it, has opened an important new avenue of research. For more information go to https://oir.nih.gov/wals/2015-2016/re... Author: Carlos Zarate, M.D., National Institute of Mental Health, NIH Permanent link: http://videocast.nih.gov/launch.asp?1...

Severe Lactic Acidosis Reversed By Thiamine Within 24 Hours

Severe lactic acidosis reversed by thiamine within 24 hours 1Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, A-8036 Graz, Austria Karin Amrein: [email protected] ; Werner Ribitsch: [email protected] ; Ronald Otto: [email protected] ; Harald C Worm: [email protected] ; Rudolf E Stauber: [email protected] This article has been cited by other articles in PMC. Thiamine is a water-soluble vitamin that plays a pivotal role in carbohydrate metabolism. In acute deficiency, pyruvate accumulates and is metabolized to lactate, and chronic deficiency may cause polyneuropathy and Wernicke encephalopathy. Classic symptoms include mental status change, ophthalmoplegia, and ataxia but are present in only a few patients [ 1 ]. Critically ill patients are prone to thiamine deficiency because of preexistent malnutrition, increased consumption in high-carbohydrate nutrition, and accelerated clearance in renal replacement. In retrospective [ 2 ] and prospective [ 3 , 4 ] studies, a substantial prevalence of thiamine deficiency has been described in both adult (10% to 20%) and pediatric (28%) patients. Thiamine deficiency may become Continue reading >>

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  1. beyondthesmile

    Does keto affect blood pressure?

    I was pleasantly surprised to find that my blood pressure has dropped (a good thing). This past summer my diastolic number was always 80ish, usually a bit higher than that. I checked my blood pressure a few times a few days ago and found that my BP has dropped to 107/74 (108/75 at one point). I don't think this is just from working out because I was working out in the summer and my BP didn't change much.
    The only thing I can think of is that since starting keto I eat less processed food, which are usually laden with sodium. But could this change make a difference in such a short time?
    Does keto itself (either being in ketosis, or eating a higher fat, low carb diet) affect blood pressure? I'm not complaining, just wondering what I can attribute this positive change to

  2. CanuckTank

    you betcha, mine dropped as well. Less fat, less blood pressure.

  3. DecemberDays86

    It's two things. Like you said, the low-sodium nature of keto helps reduce blood pressure. The other thing is that your body tends to hold onto less water when you have little to no carbohydrates to burn off. This further reduces the amount of water in your body and makes your BP drop.
    My BP is usually 120/70 and on keto it can get as low as 100/60 in the morning. Stay hydrated!

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https://www.facebook.com/drinkhealthy... - Do you want to learn how to get rid of lactic acid as an athlete, and start recovering quicker with more energy? Learn how to reduce lactic acid symptoms and increase your performance. Getting rid of lactic acid may be easier than you have imagined. Many professional athletes know the importance of eliminating lactic acid so they can recover quicker and perform at an optimal level. Start flushing out that lactic acid today! Many people suffer from lactic acidosis symptoms and are rigorously searching for a lactic acid treatment. More and more athletes are searching for solutions on how to get rid of lactic acid. In this video you will learn what a professional football player from the Seattle Seahawks is using to eliminate lactic acid after his workouts, practices, and NFL games. Learn how to make lactic acid a symptom of the past. Begin your journey to faster recovery today. See what the pro's are using to reduce lactic acid, recover quicker, and have more energy. Uncertain of what lactic is? Here is the definition https://en.wikipedia.org/wiki/Lactic_... Contact me for more information on getting rid of lactic acid FB: http://www.facebook.com/duncan.fraser... IG: http://www.instagram.com/kangendunc [email protected] See a full demonstration of this solution that helps get rid of lactic acid https://www.youtube.com/watch?v=MTxR9... Duncan Fraser 0:00 - 0:13 - Introduction 0:14 - 2:11 - Shan Stratton and Michael Robinson Discuss how to get rid of lactic acid 2:11 - 2:21 - 4 benefits of this incredible technology 2:21 - 2:39 - Conclusion Get in contact with me if you have problems with lactic acid and learn more on my FB page. Visit my Facebook page below. https://www.facebook.com/drinkhealthy...

Lactic Acidosis

Lactic acidosis is a medical condition characterized by the buildup of lactate (especially L-lactate) in the body, which results in an excessively low pH in the bloodstream. It is a form of metabolic acidosis, in which excessive acid accumulates due to a problem with the body's metabolism of lactic acid. Lactic acidosis is typically the result of an underlying acute or chronic medical condition, medication, or poisoning. The symptoms are generally attributable to these underlying causes, but may include nausea, vomiting, rapid deep breathing, and generalised weakness. The diagnosis is made on biochemical analysis of blood (often initially on arterial blood gas samples), and once confirmed, generally prompts an investigation to establish the underlying cause to treat the acidosis. In some situations, hemofiltration (purification of the blood) is temporarily required. In rare chronic forms of lactic acidosis caused by mitochondrial disease, a specific diet or dichloroacetate may be used. The prognosis of lactic acidosis depends largely on the underlying cause; in some situations (such as severe infections), it indicates an increased risk of death. Classification[edit] The Cohen-Woods Continue reading >>

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  1. boobear

    Hi everyone, I've done keto/low carb on/off last few years. Got really keto serious three weeks ago. On the whole last week my husband pretty much wanted to puke every time I spoke near him as he said my breath was soooo bad. I drink tons of water, chew gum etc. It was making me so self conscious that I went off the next day. It's been two days off and Breath is better but I really hate the way I feel eating carbs. Is there any tips for the keto breath, will it pass, and if so after how long??? It is literally the only thing that stops me from going back! Thanks in advance!

  2. Jessica

    They say that burning fat can cause bad breath due to chemicals released in the process. It's metabolic and not hygiene related. It doesn't usually last forever! Don't let it discourage you! Keep drinking lots of water

  3. boobear

    I'm trying really hard not too! I'm going to get back on tomorrow and keep ketoing but I hate being paranoid about my breath :(.

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I go over six of my favorite products I use. The first three kill fungus in different locations in the body. The fourth cleans dead fungus out of the body. The last two are probiotics to bring in the good organisms. Please like, share and subscribe to my YouTube page to get notifications whenever I post a new video! -Dr. Schmidt You have already taken the first step to better your health by watching my video! Next, I recommend that you join our Long Distance Patient Program so that you can get diet modification and supplement recommendations designed specifically for you by me or one of my fellow practitioners in our Ann Arbor, Michigan office. You have to be a patient of our office in order to receive supplements, per our distribution agreement with the producer of the Standard Process brand supplements. Becoming a Long Distance Patient as outlined below allows you that access. In order to be part of our online patient program, you would purchase an annual membership for $200. This membership includes an initial 30 minute phone appointment with me or one of our practitioners. At that time, the practitioner will make a recommendation to you for diet modifications, supplements and the quantities that you should take. After the phone call, you are able to order supplements for a year, as needed, directly from our website and our app. We will then promptly ship the supplements out to you. Follow up phone calls with your practitioner are $125 for a 20 minute phone/SKYPE appointment. If you would like to move forward and take advantage of this opportunity, please call: (734) 302-7575 or email [email protected] to schedule your phone appointment, and make the $200 payment. You can reach us by phone Monday through Saturday 9am-5pm EST. To learn more about our office and clinical practice, go to: http://thenutritionalhealingcenter.com Since not everyone is fortunate enough to live within driving distance of Ann Arbor, Michigan, and many feel that an telephone/online consultation is not enough to meet their clinical needs, I am happy to offer you our Long Distance Patient Travel Package. The package is comprised of a series of appointments with myself or another practitioner that are time sensitive, and a time allowance of 48-72 hours in our beautiful city is required. Not only are your health issues of concern thoroughly evaluated, but you receive a comprehensive full body evaluation, two different computerized cardiac health tests, a great deal of teaching and health education, and leave with a program of diet modification and supplement support that the practitioner is confident will improve your health and quality of life. This program can initiate your relationship with our clinic, and be followed up with telephone/online consultations, or it can be incorporated into your already existing program with our clinic to further enhance the program you already have in place. The cost for the Long Distance Travel Package is $560 and includes everything mentioned above. We also have a relationship with a lovely landmark hotel conveniently located less than 2 miles from our office, that offers a reduced nightly rate to our patients. In the meantime, if you are truly interested in what we have to offer, please watch these 5 important videos of mine: https://www.youtube.com/playlist?list... If you find my info helpful, please visit my Patreon page. https://www.patreon.com/drdarrenschmi... We look forward to helping you feel your best! This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. UCC 1-308 without prejudice.

Lactic Acidosis In A Patient With Type 2 Diabetes Mellitus

Go to: Introduction A 49-year-old man presented to the emergency department complaining of dyspnea for 2 days. He had a history of hypertension, type 2 diabetes mellitus, atrial fibrillation, and a severe dilated cardiomyopathy. He had been hospitalized several times in the previous year for decompensated congestive heart failure (most recently, 1 month earlier). The plasma creatinine concentration was 1.13 mg/dl on discharge. Outpatient medications included insulin, digoxin, warfarin, spironolactone, metoprolol succinate, furosemide (80 mg two times per day; increased from 40 mg daily 1 month earlier), metolazone (2.5 mg daily; added 1 month earlier), and metformin (2500 mg in three divided doses; increased from 1000 mg 1 month earlier). Physical examination revealed an obese man in moderate respiratory distress. The temperature was 36.8°C, BP was 119/83 mmHg, and heart rate was 96 per minute. Peripheral hemoglobin oxygen saturation was 97% on room air, with a respiratory rate of 26 per minute. The heart rhythm was irregularly irregular; there was no S3 or murmur. Jugular venous pressure was about 8 cm. There was 1+ edema at the ankles. A chest radiograph showed cardiomegaly and Continue reading >>

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  1. jhinako

    I just wanted to share my experience with breaking my plateau of 5 weeks on low carb by breaking ketosis for a few days. For some info on me, I am 5'7" and started at about 173ish. I pretty effortlessly dropped to 151 lbs in 2 months on low carb, but then I stalled out. I know that wasn't super fast, but please keep in mind that these were very, very stubborn pounds for me to lose on diets past, so I was thrilled to get to 151! It's technically the lowest weight I'd seen as an adult. My goal weight is 135-140, so around 10-15 lbs left. My weight is "technically" in the normal range at this point, but I still seem to have a lot of body fat on me, especially around my stomach.
    Any way, I started low carb about 3.5 months ago, sticking to between 20-40 carbs per day(usually around 30) and it worked so well for me! I was excited, it came off really quickly. Then after 2 months, I stalled out. Just a dead stall. The scale actually went up some(~1-2lbs) some days. I persisted in low carb for the next month though, hoping it would budge, but it didn't. I dropped my carbs even lower in an effort to break it. I ate mostly eggs some day. I tried fat fasting. It wasn't happening. I began to get frustrated because the weight loss had been SO effortless in the beginning and now the scale was actually UP 2 lbs and staying there.
    So I read some stuff on how to break the plateau by changing things up, and found a few articles about temporarily and purposefully breaking ketosis for a short time and then returning to it. It was supposedly to let your hormone levels normalize again and sort of "reset" after being depleted by doing low carb for an extended period of time. I didn't really want to do it. I wanted to stay in ketosis, but then I realized I hadn't lost any weight in nearly 5 weeks, so what did I have to lose if it was gonna take me a few days to get back in to it after this? So I did it. Many articles suggested breaking ketosis with a single meal. Or with a window of 12 hours, and then going back to low carb. But this didnt seem like long enough to "normalize" hormone levels. I wanted to make sure if I was mixing it up and doing this, that there was actually going to be a chance for some change, so I decided on 3 days.
    I broke ketosis on purpose. I was still controlled though, I knew I wanted to stay away from obvious sugars and candies for the most part and I did. But I ate rice, I had some pasta, I had a stromboli & garlic knots. I ate a cadbury scream egg too, which are my favorite, but it was just ok. I had some high carb, but very tasty Oktoberfest craft-type beers(17 carbs a piece!) and those were awesome, only had 1 or 2 though, I'm not a big drinker. I do remember feeling bloated and somewhat uncomfortable after many of these meals and it took several hours for the feeling to go away. I ate "normally", but within reason for 3 days(I didn't splurge, I didn't need too.). I ate when hungry, I ate what I wanted, I ate until I was satiated. Thankfully, I did not experience any urges to go overboard and eat everything in sight. If anything, the idea that i could have anything I wanted was not as appealing as I had thought because there were only a few things that I actually wanted to have and I got them. I found myself actually trying to scour my brain for more things I could eat on this little break that I had really wanted, and it was kinda difficult. Any way after about 3 days, I was actually quite ready to go back on plan so I did.
    On my "break" of 3 days, the scale said I went up 5 lbs--however, I was barely eating more than maintenance levels, so I knew this was false, water weight. It took 4 days for the extra 5 lbs to come off, about a pound a day. According to the keto-strips, it also took me about 4 days to go back into ketosis. Then I held around 153 for a few days(remember, I had gone up 1-2 lbs during the stall). Then, thankfully, it started it's downward trend again! A little bit came off every day, much like it did when I started low carb in the beginning! I am very happy to say today that I feel like my plateau is broken! I had an experiment and I am happy that I did it! I got to eat some things I was wanting for awhile and I learned that I can control myself better than I thought and it wasn't the end of the world.
    I think if I stall out again, I will repeat this. I can see the logic in mixing things up when what you're doing isn't working any more. It also gave me a lot of hope that I will be able to maintain my goal weight easier and helped me understand that a few days of eating some carbs didn't really have much of a negative effect for me, especially since I went back on plan. It actually seemed to help me. I will keep you updated as I continue my trip to 140ish. I completely understand that weight loss slows down as you get closer to your goal weight and I am 100% ok with this. I just want to see SOME progress for my efforts, you know. So I am happy to see a downward trend again.

  2. clackley

    Can't argue with success! Congrats!
    A couple of questions.... how long has it been since you have been back in ketosis? How much below your 153lb. mark have you gotten?
    Thanks for sharing!

  3. Patience

    I am also curious about your age . . . . your rate of loss sounds fast to me.
    I am in my mid-60s and was losing ~ 2 lbs a month for well over a year. My losses came to a crashing halt this summer, eating much the same as before.

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