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Intracellular Acidosis Definition

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https://www.facebook.com/drinkhealthy... - Do you want to learn how to get rid of lactic acid as an athlete, and start recovering quicker with more energy? Learn how to reduce lactic acid symptoms and increase your performance. Getting rid of lactic acid may be easier than you have imagined. Many professional athletes know the importance of eliminating lactic acid so they can recover quicker and perform at an optimal level. Start flushing out that lactic acid today! Many people suffer from lactic acidosis symptoms and are rigorously searching for a lactic acid treatment. More and more athletes are searching for solutions on how to get rid of lactic acid. In this video you will learn what a professional football player from the Seattle Seahawks is using to eliminate lactic acid after his workouts, practices, and NFL games. Learn how to make lactic acid a symptom of the past. Begin your journey to faster recovery today. See what the pro's are using to reduce lactic acid, recover quicker, and have more energy. Uncertain of what lactic is? Here is the definition https://en.wikipedia.org/wiki/Lactic_... Contact me for more information on getting rid of lactic acid FB: http://www.facebook.com/duncan.fraser... IG: http://www.instagram.com/kangendunc [email protected] See a full demonstration of this solution that helps get rid of lactic acid https://www.youtube.com/watch?v=MTxR9... Duncan Fraser 0:00 - 0:13 - Introduction 0:14 - 2:11 - Shan Stratton and Michael Robinson Discuss how to get rid of lactic acid 2:11 - 2:21 - 4 benefits of this incredible technology 2:21 - 2:39 - Conclusion Get in contact with me if you have problems with lactic acid and learn more on my FB page. Visit my Facebook page below. https://www.facebook.com/drinkhealthy...

Hyperglycaemic Crises And Lactic Acidosis In Diabetes Mellitus

Hyperglycaemic crises are discussed together followed by a separate section on lactic acidosis. DIABETIC KETOACIDOSIS (DKA) AND HYPERGLYCAEMIC HYPEROSMOLAR STATE (HHS) Definitions DKA has no universally agreed definition. Alberti proposed the working definition of “severe uncontrolled diabetes requiring emergency treatment with insulin and intravenous fluids and with a blood ketone body concentration of >5 mmol/l”.1 Given the limited availability of blood ketone body assays, a more pragmatic definition comprising a metabolic acidosis (pH <7.3), plasma bicarbonate <15 mmol/l, plasma glucose >13.9 mmol/l, and urine ketostix reaction ++ or plasma ketostix ⩾ + may be more workable in clinical practice.2 Classifying the severity of diabetic ketoacidosis is desirable, since it may assist in determining the management and monitoring of the patient. Such a classification is based on the severity of acidosis (table 1). A caveat to this approach is that the presence of an intercurrent illness, that may not necessarily affect the level of acidosis, may markedly affect outcome: a recent study showed that the two most important factors predicting mortality in DKA were severe intercurrent Continue reading >>

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  1. Santosh Anand

    Insulin plays a key role in helping sugar (glucose) enter your cells, thus providing them energy. When your cells don't get the glucose they need for energy, your body begins to burn fat for energy, which produces ketones. Ketones are acidic and so when they build up in the blood, they make the blood more acidic, leading to the condition called diabetic ketoacidosis (DKA).
    Now, in type-1 diabetes, there is no insulin production whereas in type-2, there is impairment of insulin production. Thus why Type-2 diabetic people hardly get DKA.
    Note: Diabetic ketoacidosis is a serious condition that might lead to diabetic coma or even death.

  2. Lucas Verhelst

    In order for the cells in your body to access the glucose in your bloodstream so they can use it as energy they need insulin. Insulin acts like a key, opennin the cell door to allow the entry of glucose. Type 1 diabetics produce no insulin and need to inject it, thus the amount of insulin they have is strictly limited. Once they run out of insulin the glucose remains in the blood stream. If this occurs over a long period of time their blood glucose levels will rise due to the release of glucose from the liver. High blood sugar levels causes ketoacidosis which leads to coma and death.

  3. Keith Phillips

    Although type 2 diabetics suffer from insulin resistance, the condition rarely has an absolute negative effect on the bodies ability to convert glucose to usable energy. Type 1 diabetics have little or no ability to produce insulin. With the exception of neural cells, the rest of the body which without insulin is experiencing starvation, will consume its own tissues. (this is how people have endured periods of famine). This process however produces by products that eventually overwhelm the body's ability to process toxins.

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

Acidosis

For acidosis referring to acidity of the urine, see renal tubular acidosis. "Acidemia" redirects here. It is not to be confused with Academia. Acidosis is a process causing increased acidity in the blood and other body tissues (i.e., an increased hydrogen ion concentration). If not further qualified, it usually refers to acidity of the blood plasma. The term acidemia describes the state of low blood pH, while acidosis is used to describe the processes leading to these states. Nevertheless, the terms are sometimes used interchangeably. The distinction may be relevant where a patient has factors causing both acidosis and alkalosis, wherein the relative severity of both determines whether the result is a high, low, or normal pH. Acidosis is said to occur when arterial pH falls below 7.35 (except in the fetus – see below), while its counterpart (alkalosis) occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to separate the main causes. The rate of cellular metabolic activity affects and, at the same time, is affected by the pH of the body fluids. In mammals, the normal pH of arterial blood lies between 7.35 and 7.50 depending on the species (e.g., healt Continue reading >>

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  1. RCFletcher

    This is a general and interesting article which explains how ketosis works. the bit which alarmed me was about drinking if in ketosis. It also explains why people appear to get drunk quicker - it seems they're not drunk but their brains are short of fuel!
    If the moderators would like to move this post please do. I thought it was of such general interest that it should be here.
    Enjoy!
    http://www.sun.ac.za/med_physbio/med_physiology/dept/ketosis.htm
    DO NOT DRINK ALCOHOL IF YOU ARE KETOTIC!
    Alcohol is a powerful inhibitor of gluconeogenesis. In fact, it forces part of the gluconeogenic metabolic process into reverse. This means that if all the glucose in the blood is being derived from gluconeogenesis then the consumption of alcohol will inevitably cause the blood glucose level to fall. Worse still, the alcohol also stops ketone body production, thus leaving the brain entirely without fuel.
    A person who is ketotic is 100% reliant on gluconeogenesis to maintain adequate levels of glucose in the blood. If, under these circumstances alcohol is taken, the person will become disorientated and might lose consciousness, not just from the alcohol, but from low blood sugar. Needless to say, this could be very dangerous, and even fatal.
    Alcohol does not have these effects if the glycogen stores in the liver are normal. Under these circumstances the blood glucose level in the blood is maintained by the breakdown of liver glycogen, a process that is not influenced by alcohol. If a person becomes confused under these circumstances it is due simply to the pharmacological effects of the alcohol!

  2. kimberlyw

    OK - but there's a difference between slamming down shots of vodka and having a glass or two of wine.
    I mean - I personally have never noticed a difference - but then I don't drink much.
    Thanks for the article :D
    ~Kimberly

  3. BigJ

    Ehh.. It just means I'm a cheaper drunk. Getting loaded is hard on the brain cells no matter what :)
    Thanks for the article though!

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If you have a hard time feeling your pecs working when you bench press, THIS is for you. It's an excellent technique for forcing the pecs into a better position to contract when doing a bench press...and this will help you build a bigger chest faster! http://www.thebestchestexercises.com To use this technique, you'll need a bench and a single square Step riser/platform...(you'll likely have to raid the cardio section of your gym to find one of these). I got mine for dirt cheap at a garage sale and found it to be an extremely versatile piece of training equipment, beyond just doing stepping exercises. The elevation of the upper back forces the chest to expand due to the arch in the lower back. This helps get your shoulders back, which reduces their involvement in the press. (I also find that because my head is not pressing into the bench, the base of support is primarily the upper back, which tends to load the pecs a bit more effectively.) So essentially, instead of your chest being in a flat, pancake position (which can easily happen when pressing for more than 1 rep), your chest is puffed out and your pecs are in a MUCH better anatomical position to contract through the entire set. Famous bodybuilding trainer John Parrillo created a bench with this position in mind (chest forced to expand), called the Parrillo Arched Bench. This simple addition of the Step riser to a normal flat bench helps get you into that similar position for optimal chest development without needing to have the full bench (which is rare in gyms and can be hard to find). This exercise can also be done in the power rack using a barbell instead of dumbbells, though I do find dumbbells to be more effective for really feeling the pecs working on this exercise. You can also use this setup for dumbbell flyes for increased pec stretch and contraction. This is an excellent one to finish off your pecs, following the pressing. I like to hold the dumbbells at a 45 degree angle at the bottom...I find it much easier on my shoulder joints while still getting a great stretch at the bottom. You can keep the palms in a neutral position, if you prefer. This simple addition to your bench press will make a BIG difference in your pec development. Pull back on the heavy barbell training for a few weeks and put this one to work instead...you'll notice definite improvement in your pecs within a few short weeks! -------------------------------------------------------------------------- Want more training info like this? Make sure to subscribe to my YouTube channel and my Facebook page for more unique exercises and unconventional training methods: YouTube Channel http://www.youtube.com/subscription_c... Facebook http://www.facebook.com/nicknilssonma... Instagram https://www.instagram.com/nicknilsson1/ Websites http://www.fitstep.com http://www.madscientistofmuscle.com Nick Nilsson The Mad Scientist of Muscle -~-~~-~~~-~~-~- Want some killer bicep training? Watch: "Get Big Arms...Get a Raging Pump in Your Biceps With a Non-Stop Superset of Curls and Chins" https://www.youtube.com/watch?v=2X2Q9... -~-~~-~~~-~~-~-

Hemodynamic Consequences Of Severe Lactic Acidosis In Shock States: From Bench To Bedside

Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside Kimmoun et al.; licensee BioMed Central.2015 The Erratum to this article has been published in Critical Care 2017 21:40 Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these deleterious effects have not been fully determined and their respective consequences on organ failure are still poorly defined, particularly in humans. Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics. Consequently, the essential treatment for lactic acidosis in shock patients is to correct the cause. It is unknown, however, whether symptomatic pH correction is beneficial in shock patients. The latest Surviving Sepsis Campaign guidelines recommend against the use of buffer therapy with pH 7.15 and issue no recommendation for pH lev Continue reading >>

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  1. Manicarrie

    Hi, was just admitted with severe dka due to a stomach bug and poor sick day education. Now I am home am doing nothing but sleep and feel generally weak, is this normal?

  2. Redkite

    Sorry to hear this. I would say that recovery from a stomach bug leaves you exhausted and washed out even without the DKA. Have you now been given some sick day advice?
    My son has had numerous gastro bugs, as is typical with young children, but a nightmare when they have type 1. I have had to deal with them when he was on mixed insulins, MDI, and a pump, and it is definitely easier with a pump. What type of insulin regimen are you on? The key thing is that even if you are vomiting and not eating, you still need some insulin.
    When my son has been vomiting, I have tested his BG hourly, and also tested his blood ketones. Do you have a blood ketone meter? If not I would recommend it, as you can then see instantly if your ketones are rising to dangerous levels, whereas with the urine ketone strips, you are only seeing what the ketones were several hours before. If his BGs are high, obviously I can correct with more insulin, but usually with a stomach bug he runs at very low BG levels, with lots of hypos, and ketones begin to creep in. We try to tackle these with by getting him to have small sips of lucozade, teaspoons of full-sugar jelly, sugary ice lollie, anything he can bear to have, accompanied by tiny boluses of insulin. If, despite this, his ketones continue to rise, and/or we can't keep his levels out of the hypo range, we know we'd have to go into hospital.
    Do you live alone or is there someone who could help you with overnight testing when you are ill?
    One other thing - after this type of illness it takes the gut 2-3 weeks to heal, and during this time you may find your food absorbs more slowly, and you may find it helpful to take your insulin after eating.
    Hope you feel better soon

  3. Manicarrie

    Yeah they weren't letting me out without sick day advice!!! Had already started to recover from bug the day before I to really ill, should have asked hospital about recovery before I left. Stupid me, assumed that once fluids sorted and ketones down I would be back to normal.

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