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In The Renal Response To Metabolic Acidosis Quizlet

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Step 1 Secrets: Acid-base

Via Cl/HCO3 exchange process in the colon. Nonanion gap metabolic acidosis can alternatively be described as what? What are the two causes of nonantion gap metabolic acidosis? In appropriate renal response to nonanion gap metabolic acidosis, what should be excreted? In acidosis, failure of the kidney to excrete NH4 is called what condition? What are the three renal tubular acidosis? Renal compensation for acute respiratory acidosis Renal compensation for chronic respiratory acidosis Renal compensation in acute respiratory alkalosis Renal compensation in chronic respiratory alkalosis High altitude and pregnant women lead to what? Volume depletion leads to what? What is trying to be retained? What hormone comes into play and what does it do? Contraction alkalosis. Retain Na = increased bicarbonate reabsorption. Aldosterone promotes Na retention in exchange for K and H in distal tubule Hypokalemia leads to what? What is renal trying to do to correct this? How are K and H shifting trancellulary? Intracellular acidification leads to what renally? Metabolic alkalosis. K retention results in increased H secretion in distal tubule. K shifts out, H shifts in resulting in lowered H. Intrace Continue reading >>

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  1. MarkM

    Originally Posted by 10xdiabetic
    ... the units of insulin I am having to take seem excessive. I feel my body is no longer sensitive to the insulin. ... Getting most calories from fat can be expected to reduce insulin sensitivity. There is a whole lot of science behind this, but the bottom line is that when in ketosis (eating low carb, high fat), we need a lot more insulin than the consumed carbs suggests. So you will have to adjust insulin dosing accordingly. Once you have done that, maintaining good control should get a lot easier.
    I gave up on the ketogenic diet because sticking to it was just too hard. Especially in China, where I have been living for a while. After switching back to a 'normal' diet, my control became somewhat more difficult, but my insulin requirements went down. I have become more insulin sensitive, and my TDD is now lower than it has ever been. Using a pump also helps with that, but I suspect that much of the difference is because of less fat in the diet.

  2. hughman

    The only thing constant about insulin dosing for me over the last 40+ years is change. At one point I was taking at least a total of 120 units a day, but that was with massive aspartame consumption. Once I stopped diet pop (soda), I now take a total of around 60 units, and take it totally differently amounts at different times than I used to. I could take less insulin if I ate less carbs, but we all make our decisions on our lifestyle.
    Everyone is different, and our environment and what we consume effects us all differently. And women have it even tougher with those pesky hormones.

  3. 10xdiabetic

    Thank you for that insight. This is what my feeling was also. I tried to find science to confirm my hypothesis. Could you share an article / source where you read about that so I can explore this further?

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Review of the physiology surrounding renal control of acid base balance.

Renal Control Of Acid-base Balance

What is the effect of excess H+ on plasma Ca2+? Increased H+ = more free Ca2+ = hypocalcemia, increased serum calcium What two factors do the strength of a buffer to minimize pH change depend on? -Mixture of weak acid and its conjugate base in aqueous solution -Chemical buffers minimize but don't completely prevent pH changes caused by strong acid or base Ability ('strength') of buffer to minimize pH changes depends on: -Concentrations of buffer system components -Nearness of buffer's pKa to pH of solution What controls the concentration of the volatile acid in the body? In chemical equilibrium with CO2, a volatile gas: H2CO3 <-> CO2 + H2O Pulmonary ventilation controls H2CO3 concentration in body fluids Fixed acids: non-carbonic acids generated metabolically (e.g. sulfuric, phosphoric acids) Initially neutralized by buffers in body fluids What is the equation for oxidative metabolism of CO2? Nonvolatile acids: Lactic acid, ketone acids, sulfuric acid, phosphoric acid, hydrochloric acid Removed by kidneys through urine (cannot be removed by ventilation) What are the 3 lines of defense against pH changes? Patient with acidosis has H+ go into RBCs and is buffered by Hb What is the e Continue reading >>

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  1. edvedr

    hi guys, i'm new here. i've done no carb diets before and i used ketosticks. this time i'm doing the "anabolic diet" and i am using a glucose meter. i've asked around my bodybuilding forums but not too many people are familiar with ketosis diets. what exactly should your glucose levels be at when your in ketosis? i've gotten down to 50 mg/dl but can't stay that low. i seem to be staying in the 70-90 range. and thats not in ketosis from what i've been reading. my diet is in check. i'm not a newbie, i've been into BB for quite a few years and i use to calculating EVERYTHING i eat. my carb count is def under 20 and on some days its below 10. but yet i just don't get any lower than that. i don't drink anything with aspartame, citric acid. just plain water 1-2 gallons a day. even when i do cardio (which is everyday) afterwards my levels rarely drop below 70. i don't eat too much protein, its under 1gram per lb of body weight. i don't understand. i am seeing results, not as much as i want but its only been 2 weeks. i'm not really complaining from lack of results, i'm just tryin to get a better understanding of everything. and this isn't making sense to me. thanks for any help! :)

  2. edvedr

    i think i just put this in the wrong forum....sorry if i did. the all say low carb and i just realized thats the name here. oops sorry

  3. mio1996

    The goal in ketosis is to achieve a stable, normal glucose reading. 70-90 is perfectly normal. It should never be 50!

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Description Dextrose 5% in Water (D5W) raises total fluid volume it is also helpful in rehydrating and excretory purposes. Type of Solution Dextrose 5% Water Isotonic then hypotonic (once inside the body) Classification Isotonic then hypotonicD5LRS (Lactated Ringers Solution) IV Fluid Nonpyrogenic Parenteral fluid Electrolyte Nutrient replenisher Contents Dextrose Hydrous 50gm/L Mechanism of action Dextrose provides a source of calories. Dextrose is readily metabolized, may decrease losses of body protein and nitrogen, promotes glycogen deposition and decreases or prevents ketosis if sufficient doses are provided Indications Lactated Ringers and 5% Dextrose Injection, is indicated as a source of water, electrolytes and calories or as an alkalinizing agent. Contraindications solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products. Dose As directed by a physician. Dosage is dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container perm

Chapter 25 - Fluids Flashcards | Quizlet

the various body compartments contain the required amount of water, proportioned accodring to their needs. Rapid movement between ECF and ICF in response to changes in osmotic concentration of ECF and reach equilibrium within minutes to hours primary way in which water moves in and out of body compartments. The concentrations of solutes in the fluids are a major determinant of fluids. volume of ICF is larger than ECF (volume of water inside the cells). 1. Water absorbed across digestive epithelium - gained 2. Water vapor lost at skin and lungs - lost compounds that dissociate into ions (Na, Cl, etc.) develops when water losses outpace water gains. Loss of water - ECF concentration increases - water moves out of ICF to ECF to get both isotonic, similar to before the fluid loss. 3. found and secreted at kidneys. in bodily fluids 2. moves between fluid compartments and regulate osmotic pressure between compartments. 1. most abundant material in the body (98% stored in bone). 2. structural component of bones and teeth, essential for maintenance of muscle tone, and excitability of nervous and muscle tissue. 1. stored in bone matrix, but 1% remain is intracellular - cofactor 2. activate Continue reading >>

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  1. atcgirl

    I started 5:2 in september and initially tried to spread my 500 calories accross the day, but I lost no weight and couldn’t cope with the hunger pangs. Then I started just having all my 500 calories at dinner, with zero calories during the day (just a green tea in the morning for the caffeine), and I started losing a pound a week. I figure that my body needed to go into ketosis to actually shift the pounds.
    I am sick of green tea, I actually hate it. Black coffee isn’t an option because it gives me bad breath, so I’m going to need to go back to black tea with milk (no sugar). I figure semi skimmed is better than skimmed because having more fat in it leave less room for lactose and I only have a splash of milk, but will this bring me out of ketosis for any significant period?
    I know that my body will use some of the lactose as energy, I figure it can’t be for that long, but it’s going to try and do that as efficiently as possible; I don’t know enough about the science behind all this.
    Body building forums state all sorts of numbers from 10 calories to 50 and most of my googling has been fruitless. Anyone know?
    Thanks

  2. Pot-bellied Heron

    My understanding is that you won’t get into ketosis on the 5:2 though I haven’t really looked into it.

  3. atcgirl

    Some sites I’ve read suggest ketosis starts 8 to 12 hours after your last meal, others suggest it’s actually much longer – 48 hours. Which had me confused anyway.
    Normally i’d just experiment but I have a month until my love handles need to not show under my wedding dress and would prefer not to delay further weightloss
    It’s so little milk I have to believe it won’t make a difference! Also hoping it won’t affect IGF-1 levels but I think lots of people on here have already proved that it doesn’t because their levels have dropped even though they spread the calories out during the day.

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