Hyper K In Dka

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Hyperkalemia In Diabetic Ketoacidosis - Sciencedirect

Volume 299, Issue 3 , March 1990, Pages 164-169 Author links open overlay panel MilfordFulopMD Get rights and content Patients with diabetic ketoacidosis tend to have somewhat elevated serum K+ concentrations despite decreased body K+ content. The hyperkalemia was previously attributed mainly to acidemia. However, recent studies have suggested that organic acidemias (such as that produced by infusing beta-hydroxybutyric acid) may not cause hyperkalemia. To learn which, if any, routinely measured biochemical indices might correlate with the finding of hyperkalemia in diabetic ketoacidosis, we analyzed the initial pre-treatment values in 131 episodes in 91 patients. Serum K+correlated independently and significantly (p < 0.001) with blood pH (r = 0.39), serum urea N (r = 0.38) and the anion gap (r = 0.41). The mean serum K+ among the men was 5.55 mmol/ 1, significantly higher than among the women, 5.09 mmol/1 (p < 0.005). Twelve of the 16 patients with serum K+ 6.5 mmol/1 were men, as were all eight patients with serum K+ 7.0 mmol/1. Those differences paralleled a significantly higher mean serum urea N concentration among the men (15.1 mmol/1) than the women (11.2 mmol/1, p < 0.01). Continue reading >>

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Popular Questions

  1. nurseprnRN

    The hypokalemia comes when the patient gets treated with insulin, driving the glucose and K+ into the cells. The kidneys can't (and won't) move so much out through urine with the excess glucose to make for hypokalemia.

  2. Esme12

    There can be a brief period of hypoglycemia in the early stages of an elevated blood sugar (polyuria)....but by the time "ketoacidosis" sets in the Serum potassium is elevated but the cellular potassium is depleted (all that shifting that goes on)
    Diabetic ketoacidosis

  3. April2152

    So pretty much what we would observe clinically is hyperkalemia because the osmotic duiresis does not move serum potassium significantly?

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