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How To Induce Ketoacidosis

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high blood sugar, low blood pH, and ketoacids in either the blood or urine. The primary treatment of DKA is with intravenous fluids and insulin. Depending on the severity, insulin may be given intravenously or by injection under the skin. Usually potassium is also needed to prevent the development of low blood potassium. Throughout treatment blood sugar and potassium levels should be regularly checked. Antibiotics may be required in those with an underlying infection. In those with severely low blood pH, sodium bicarbonate may be given; however, its use is of unclear benefit and typically not recommended. Rates of DKA vary around the world. About 4% of people with type 1 diabetes in United Kingdom develop DKA a year, while in Malaysia the condition affects about 25% a year. DKA was first described in 1886 and, until the introduction of insulin therapy in the 1920s, it was almost universally fatal. The risk of death with adequate and timely treatment is currently around 1–4%. Up to 1% of children with DKA develop a complication known as cerebral edema. The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. Those who measure their glucose levels themselves may notice hyperglycemia (high blood sugar levels). In severe DKA, breathing becomes labored and of a deep, gasping character (a state referred to as "Kussmaul respiration"). The abdomen may be tender to the point that an acute abdomen may be suspected, such as acute pancreatitis, appendicitis or gastrointestinal perforation. Coffee ground vomiting (vomiting of altered blood) occurs in a minority of people; this tends to originate from erosion of the esophagus. In severe DKA, there may be confusion, lethargy, stupor or even coma (a marked decrease in the level of consciousness). On physical examination there is usually clinical evidence of dehydration, such as a dry mouth and decreased skin turgor. If the dehydration is profound enough to cause a decrease in the circulating blood volume, tachycardia (a fast heart rate) and low blood pressure may be observed. Often, a "ketotic" odor is present, which is often described as "fruity", often compared to the smell of pear drops whose scent is a ketone. If Kussmaul respiration is present, this is reflected in an increased respiratory rate.....

Childhood Ketoacidosis

Patient professional reference Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find one of our health articles more useful. Diabetic ketoacidosis (DKA) is the leading cause of mortality in childhood diabetes.[1]The primary cause of DKA is absolute or relative insulin deficiency: Absolute - eg, previously undiagnosed type 1 diabetes mellitus or a patient with known type 1 diabetes who does not take their insulin. Relative - stress causes a rise in counter-regulatory hormones with relative insulin deficiency. DKA can be fatal The usual causes of death are: Cerebral oedema - associated with 25% mortality (see 'Cerebral odedema', below). Hypokalaemia - which is preventable with good monitoring. Aspiration pneumonia - thus, use of a nasogastric tube in the semi-conscious or unconscious is advised. Deficiency of insulin. Rise in counter-regulatory hormones, including glucagon, cortisol, growth hormone, and catecholamines. Thus, inappropriate gluconeogenesis and liver glycogenolysis occur compounding the hyperglycaemia, which causes hyperosmolarity and ensui Continue reading >>

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  1. Michael Simpson

    Diabetic ketoacidosis (the formal name, and the one most diabetics use, abbreviating it as DKA) can happen in Type 2 diabetics, but as you implied it is rare.
    Type 1 diabetics totally lack or have insufficient amounts of insulin. So the body produces the antagonistic hormone, glucagon, because there's no insulin, which to the body means there's low glucose. Glucagon then induces the liver to use fat as energy, producing ketone bodies while also forcing the liver to convert glycogen to glucose. Unfortunately, the blood glucose levels are high because the Type 1 Diabetic has no insulin. This causes the blood osmolarity to skyrocket, and the kidneys try to compensate by removing ketones and glucose from the blood.
    Since the kidneys have a maximum capacity to clear excess glucose from the blood, the blood becomes more acidotic and ketone bodies rise at the same time. And that leads to more serious issues like coma and death.
    The feedback systems are all broken, so the body spins out of control. It is often the first sign of Type 1 diabetes.
    So the one difference between Type 1 and Type 2 diabetics is that Type 1 has no insulin, but Type 2 generally has insulin in the blood to suppress the release of glucagon. And this is why it's rare in Type 2 diabetics.

  2. Liang-Hai Sie

    We need insulin to be able to utilize glucose, type 2 has some insulin, not enough because of the insulin resistance, type 1 don't, so in type one ketosis can develop because the lack of insulin causes the body to burn fat that forms ketones if no inslin is administered. I knew a man who every time he was arrested by intent "forgot" to inject his insulin so ended in hospital with a keto-aciditic diabetic coma, out of jail.

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FORD BREWER MD MPH . PrevMedHeartRisk.com The TAME study was finally funded. Targeting Aging with Metformin aims to slow the aging process. It has been developed and approved by the National Institute of Aging and the FDA. The principal investigator, Nir Barzilai, is excited about changing the paradigm and getting big PHARMA to actually fund research for drugs for aging. Currently, PHARMA only funds research for drugs for disease - not anti-aging. What is it about getting older that causes heart disease, kidney disease, cancer, dementia and all these other problems of aging? Let's put the "splitters" (specialists like cardiologists, nephrologists, neurologists, etc) out of business. How? By stopping the cellular components of the aging process. That's where metformin comes in. It helps slow down the major biochemical challenge of aging: glucose metabolism. Enzymes like insulin membrane receptors, mTOR, ampk, and SIRT1 are implicated. And they are positively impacted by metformin. Metformin is cheap ( free at many pharmacies now). It's been used for decades. It's popular ( the #1 oral drug for early type 2 diabetes). And it's safer than you think. Some medical sites ( like Mayo) still incorrectly list lactic acidosis as a problem with metformin. But look up the multiple Cochrane analyses on this. About Dr. Brewer - Ford Brewer is a physician that started as an Emergency Doctor. After seeing too many patients coming in dead from early heart attacks, he went to Johns Hopkins to learn Preventive Medicine. He went on the run the post-graduate training program (residency) in Preventive Medicine at Hopkins. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has over 500 primary care/ prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, stroke, and diabetes prevention clinic. At PrevMed, we focus on heart attack and stroke and Type 2 diabetes prevention by reducing or eliminating risk through attentive care and state-of-the-art genetic testing, imaging, labs and telemedicine options. We serve patients who have already experienced an event as well as those have not developed a diagnosis or event. Our team of senior clinicians includes internationally recognized leaders in the research and treatment of cardiovascular disease, preventive medicine and wellness. We also provide preventive medicine by telemedicine technology to over 30 states. Contact Dr. Brewer at [email protected] or visit http://prevmedheartrisk.com.

What Is The Metformin Dosage Protocol In The Tame (targeting Aging W/ Metformin) Longevity Study?

There are a few points to consider: Metformin acts in a hormetic way which means that a low dose may have health benefits whereas a higher dose is associated with toxicity and dysfunction. It is very difficult to extrapolate the human dose from experiments in mice. It is known that the epigenetic profile and microRNA activity is different in different animals, and that humans have unique microRNA profiles. This means that any dosage found to be ideal in mice cannot easily be extrapolated to humans. See this quote from the paper below: "....comparison of gene expression regulation between species indicated that there is a significant difference between humans and mice possibly questioning the effectiveness of the latest as experimental models of human diseases ....Homo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity). Therefore, it would be best to consider human experiments which calculate doses appropriate for humans. The dose currently in use in humans is 1-2 g a day. Continue reading >>

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  1. Michael Simpson

    Diabetic ketoacidosis (the formal name, and the one most diabetics use, abbreviating it as DKA) can happen in Type 2 diabetics, but as you implied it is rare.
    Type 1 diabetics totally lack or have insufficient amounts of insulin. So the body produces the antagonistic hormone, glucagon, because there's no insulin, which to the body means there's low glucose. Glucagon then induces the liver to use fat as energy, producing ketone bodies while also forcing the liver to convert glycogen to glucose. Unfortunately, the blood glucose levels are high because the Type 1 Diabetic has no insulin. This causes the blood osmolarity to skyrocket, and the kidneys try to compensate by removing ketones and glucose from the blood.
    Since the kidneys have a maximum capacity to clear excess glucose from the blood, the blood becomes more acidotic and ketone bodies rise at the same time. And that leads to more serious issues like coma and death.
    The feedback systems are all broken, so the body spins out of control. It is often the first sign of Type 1 diabetes.
    So the one difference between Type 1 and Type 2 diabetics is that Type 1 has no insulin, but Type 2 generally has insulin in the blood to suppress the release of glucagon. And this is why it's rare in Type 2 diabetics.

  2. Liang-Hai Sie

    We need insulin to be able to utilize glucose, type 2 has some insulin, not enough because of the insulin resistance, type 1 don't, so in type one ketosis can develop because the lack of insulin causes the body to burn fat that forms ketones if no inslin is administered. I knew a man who every time he was arrested by intent "forgot" to inject his insulin so ended in hospital with a keto-aciditic diabetic coma, out of jail.

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In this video, I am sharing with you the stocking stuffers that we bought for Andrew, Ashley, and Christina's Christmas stockings. Music Credit: "Deck The Halls" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 http://creativecommons.org/licenses/b... Other Places To Find Us: Address: PO Box 4773 Winchester, KY 40392 Patreon: https://www.patreon.com/tamisclock?ty=h Tamis Snapchat: tamisclock Tamis Twitter: https://twitter.com/tamisclock Tamis Pinterest: https://www.pinterest.com/tamisclock/ Tamis Instagram: https://www.instagram.com/tamisclock/ Tamis Facebook: https://www.facebook.com/tamidunnyoutube Tamis Google+: https://plus.google.com/+TamiDunn/posts Kevins Lunchtime Review: https://www.youtube.com/channel/UCRU5... Kevins Gaming & Lecturing Channel: https://www.youtube.com/channel/UCGgx... Kevins Instagram: https://www.instagram.com/moviehq/ Kevins Twitter: https://twitter.com/MovieHQ Kevins Google+: https://plus.google.com/+MovieHQ/videos Dunn Family Bloopers https://www.youtube.com/watch?v=qdjZm... Dunn Family Bloopers Part II https://www.youtube.com/watch?v=dXQ5v... Dunn Family Bloopers Part III https://www.youtube.com/watch?v=Blfg4... Ashleys Instagram: https://www.instagram.com/ashley_e_dunn/

Would You Recommend The Ketogenic Diet To An 18 Year Old Girl For Weight Loss?

I’ve been on the diet for about 6 months. I am now 18 years old. The thing about Keto is that it’s a difficult diet and requires dedication, but the results are admirable. I’ve lost about 40 pounds over the course of the first 4 months and am now at 132 pounds, exercising once a week for an hour at best. I’ll give you the info you actually need to know, and then the rest will be my response to Sally’s post :) Also, remember that most people who give advice about weight loss have never been obese or overweight to a significant degree. Weight loss is a struggle and a battle, and you cannot rely on people who only criticize from afar. Would a soldier take advice on how to shoot a rifle from a civilian who has played Call of Duty? No? Thought not. Pros: Most people on keto do not need to consciously restrict food intake, you should never feel hungry. Generally preserves muscle mass and maximizes fat loss. You can eat fat again! Do not be afraid of fat. The fattiest animals, ruminants, consume low fat, grain based diets high in fiber. In contrast, every carnivore preferentially eats the fattiest part of the animal, yet they are lean. Why in the world would we assume that human Continue reading >>

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  1. James Pearson

    We get few actual fake calls, most are at least made with good intentions, even if they don’t really require an ambulance. When it comes to a fake call, drunk-abetics can be annoying.
    A drunk driver gets pulled over by the cops, he staggers out of his car, fails a field sobriety test, then tells the officer, “I’m not drunk, I’m diabetic, and my sugar is too high, I was going home to get my insulin”. The symptoms of hyperglycemia are similar to being drunk, including ketoacidosis, which causes a smell similar to alcohol on a person’s breath.
    So, we get dragged out of bed at 0200 (if we’re lucky enough to be in bed) to check a person’s blood sugar with a glucometer, and tell the cops that whatever is going on with their prisoner, it isn’t related to blood glucose levels.
    Another similar call is the stainless steel induced myocardial infarction (SSIMI). That’s when the application of handcuffs causes the patient to experience rapid onset chest pain and shortness of breath, which they are sure is an impending heart attack, meaning they should bypass the jail and go to the ER.
    Given a choice of ER or jail, the patient will usually beat the EMTs into the ambulance. Some of them, knowing that they will go to jail as soon as the ER clears them will decide to just go with the cops and get it over with. A very few actually end up admitted to the hospital for a genuine medical problem.

    Let me also add: This isn’t meant as any slam against diabetics, only those pretenders trying to avoid consequences. If someone is diabetic, and appears drunk, it’s a serious medical emergency. Do not assume anything, get help.

  2. David Wayne

    Chest pains from an “arguement”. Usually the patient is young (20s) with no medical history, they just want to get away from the arguement. Which I understand getting away to let things cool down, but an ambulance ride to the hospital is a bit much.

  3. Scarlett DéLìon

    This isn’t actually a fake call so much as one of the weirdest calls I have ever gone on. Recently we had been paged for a female patient with abdominal pain, she was also in that age range where there was a possibility of pregnancy.
    We get to the house and I walk in, announce “Ambulance.” and….. nothing…. no reply, no moaning, no groaning, nothing. I start to search the house, going to the living room from the kitchen (came in through the garage) and no one in the living room…. strange… but then again could be in the bedroom. Knock on the first bedroom door and nothing. No one. Still no sound. Go to the next room and same thing. Eventually me and my trainee have checked all rooms in the place and theres literally no one there but us.
    At this point I’m concerned, we get in contact with dispatch and they say that there was no vehicle at the location; which is why the patient called 911.

    Eventually we give up the search and return to station. I check facebook and look up the person that called. It’s a legit person, but they’ve been posting for the past hour or two, I never messaged them but it was somewhat annoying that they never even tried to make contact with 911 again after saying “hey I got a ride” or something.

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