As fat is broken down, acids called ketones build up in the blood and urine. In high levels, ketones are poisonous. This condition is known as ketoacidosis. Diabetic ketoacidosis (DKA) is sometimes the first sign of type 1 diabetes in people who have not yet been diagnosed. It can also occur in someone who has already been diagnosed with type 1 diabetes. Infection, injury, a serious illness, missing doses of insulin shots, or surgery can lead to DKA in people with type 1 diabetes. People with type 2 diabetes can also develop DKA, but it is less common. It is usually triggered by uncontrolled blood sugar, missing doses of medicines, or a severe illness. Continue reading >>
Diabetic Ketoacidosis Explained
Twitter Summary: DKA - a major complication of #diabetes – we describe what it is, symptoms, who’s at risk, prevention + treatment! One of the most notorious complications of diabetes is diabetic ketoacidosis, or DKA. First described in the late 19th century, DKA represented something close to the ultimate diabetes emergency: In just 24 hours, people can experience an onset of severe symptoms, all leading to coma or death. But DKA also represents one of the great triumphs of the revolution in diabetes care over the last century. Before the discovery of insulin in 1920, DKA was almost invariably fatal, but the mortality rate for DKA dropped to below 30 percent within 10 years, and now fewer than 1 percent of those who develop DKA die from it, provided they get adequate care in time. Don’t skip over that last phrase, because it’s crucial: DKA is very treatable, but only as long as it’s diagnosed promptly and patients understand the risk. Table of Contents: What are the symptoms of DKA? Does DKA occur in both type 1 and type 2 diabetes? What Can Patients do to Prevent DKA? What is DKA? Insulin plays a critical role in the body’s functioning: it tells cells to absorb the glucose in the blood so that the body can use it for energy. When there’s no insulin to take that glucose out of the blood, high blood sugar (hyperglycemia) results. The body will also start burning fatty acids for energy, since it can’t get that energy from glucose. To make fatty acids usable for energy, the liver has to convert them into compounds known as ketones, and these ketones make the blood more acidic. DKA results when acid levels get too high in the blood. There are other issues too, as DKA also often leads to the overproduction and release of hormones like glucagon and adrenaline Continue reading >>
Canine Diabetic Ketoacidosis (dka)
Canine diabetic ketoacidosis, sometimes known as DKA, is a potentially fatal disease that most commonly occurs in dogs with uncontrolled diabetes mellitus, although in rare cases it has been known to appear in nondiabetic dogs. This condition symptomatically resembles that of diabetes but usually goes unnoticed until a near-fatal situation is at hand. For this reason, it is important to understand the causes, symptoms and treatment options. How Canine Diabetic Ketoacidosis Develops Under normal conditions, the pancreas is responsible for producing insulin, which helps to regulate the level of glucose in the blood cells. When the pancreas is ineffectively able to create enough insulin, a dog becomes diabetic. By default, a dog's body will begin looking for alternative fuel sources, such as fat. The problem is that when too much fat is consumed by the body, the liver then begins to produce ketones. This excessive level of ketones causes the condition known as canine diabetic ketoacidosis. There are two scenarios in which this can occur: in dogs with poorly controlled diabetes and in dogs with undiagnosed diabetes. Recognizing the Symptoms Because of the potentially deadly side effects, it is crucially important that dog owners be aware of the symptoms of canine diabetic ketoacidosis. One of the more common problems associated with this illness is the extreme similarity of the warning signs to a diabetic condition. While both conditions are harmful, canine diabetic ketoacidosis represents the last step taken by the body before it surrenders to the condition. The following are some of the recognizable symptoms of canine diabetic ketoacidosis: Drinking or urinating more than usual Sudden, excessive weight loss attributed to loss of appetite General fatigue Vomiting Sudden on Continue reading >>
Ketones in the urine, as detected by urine testing stix or a blood ketone testing meter, may indicate the beginning of diabetic ketoacidosis (DKA), a dangerous and often quickly fatal condition caused by low insulin levels combined with certain other systemic stresses. DKA can be fixed if caught quickly. Diabetics of all species therefore need to be checked for ketones with urine testing stix, available at any pharmacy, whenever insulin level may be too low, and any of the following signs or triggers are present: Ketone Monitoring Needed: Little or no insulin in last 12 hours High blood sugar over 16 mmol/L or 300 mg/dL (though with low insulin, lower as well...) Dehydration (skin doesn't jump back after pulling a bit gums are tacky or dry) Not eating for over 12 hours due to Inappetance or Fasting Vomiting Lethargy Infection or illness High stress levels Breath smells like acetone (nail-polish remover) or fruit. Note that the triggers and signs are somewhat interchangeable because ketoacidosis is, once begun, a set of vicious circles which will make itself worse. So dehydration, hyperglycemia, fasting, and presence of ketones are not only signs, they're also sometimes triggers. In a diabetic, any urinary ketones above trace, or any increase in urinary ketone level, or trace urinary ketones plus some of the symptoms above, are cause to call an emergency vet immediately, at any hour of the day. Possible False Urine Ketone Test Results Drugs and Supplements Valproic Acid (brand names) Depakene, Depakote, Divalproex Sodium Positive. Common use: Treatment of epilepsy. Cefixime/Suprax Positive with nitroprusside-based urine testing. Common use: Antibiotic. Levadopa Metabolites Positive with high concentrations. Tricyclic Ring Compounds Positive. Commo Continue reading >>
What You Should Know About Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a buildup of acids in your blood. It can happen when your blood sugar is too high for too long. It could be life-threatening, but it usually takes many hours to become that serious. You can treat it and prevent it, too. It usually happens because your body doesn't have enough insulin. Your cells can't use the sugar in your blood for energy, so they use fat for fuel instead. Burning fat makes acids called ketones and, if the process goes on for a while, they could build up in your blood. That excess can change the chemical balance of your blood and throw off your entire system. People with type 1 diabetes are at risk for ketoacidosis, since their bodies don't make any insulin. Your ketones can also go up when you miss a meal, you're sick or stressed, or you have an insulin reaction. DKA can happen to people with type 2 diabetes, but it's rare. If you have type 2, especially when you're older, you're more likely to have a condition with some similar symptoms called HHNS (hyperosmolar hyperglycemic nonketotic syndrome). It can lead to severe dehydration. Test your ketones when your blood sugar is over 240 mg/dL or you have symptoms of high blood sugar, such as dry mouth, feeling really thirsty, or peeing a lot. You can check your levels with a urine test strip. Some glucose meters measure ketones, too. Try to bring your blood sugar down, and check your ketones again in 30 minutes. Call your doctor or go to the emergency room right away if that doesn't work, if you have any of the symptoms below and your ketones aren't normal, or if you have more than one symptom. You've been throwing up for more than 2 hours. You feel queasy or your belly hurts. Your breath smells fruity. You're tired, confused, or woozy. You're having a hard time breathing. Continue reading >>
How Long Does Diabetic Coma Last And How Is It Treated?
When immediately attended and given the right treatment, the diabetic patient can be quickly wakened up from the diabetic coma. Late attention to diabetic coma might take more glucose to be given to the person for better healing. The diabetic coma is connected to the metabolic abnormalities which forces the diabetic patient to the coma. If the diabetic patient stays in the coma for longer periods of time or if the patient is unattended for long time, permanant brain damage may take place or in rare instances it may lead to death of the patient. What is the Prognosis or Outlook for Diabetic Coma? Diabetic coma can be fatal. Late attention may prolong the period of treatment. A person who has been treated for long for diabetic coma is recorded to experience a brain damage. This is a dire situation but can be avoided by taking precautionary measures. Remain alert and aware to save yourself from diabetic coma. Manage your diabetic syndromes effectively to save your life. Even after the sugar level is normalized in a person, he or she will still experience nervous disorders like seizures or talking problems. Problems still persists even after recovering from diabetic coma. The recovery time cannot be predicted and depends on individual case. When immediately attended and given glucose biscuits, a person can be quickly wakened up. Late attention might take more glucose to be given to the person for better healing. Consult your doctor and take necessary guidelines on how to prevent any incident of diabetic coma or any other complexities if you are diabetic. Your doctor may prescribe you tests to determine the exact "dos and don'ts" to you on how to manage diabetes. Diabetic coma is caused by three major reasons: Severe hypolgycemia i.e., low blood sugar level Diabetic ketoacid Continue reading >>
Diabetic ketoacidosis (DKA) happens when your blood sugar is high and your insulin level is low. This imbalance in the body causes a build-up of ketones. Ketones are toxic. If DKA isn’t treated, it can lead to diabetic coma and even death. DKA mainly affects people who have type 1 diabetes. But it can also happen with other types of diabetes, including type 2 diabetes and gestational diabetes (during pregnancy). DKA is a very serious condition. If you have diabetes and think you may have DKA, contact your doctor or get to a hospital right away. The first symptoms to appear are usually: frequent urination. The next stage of DKA symptoms include: vomiting (usually more than once) confusion or trouble concentrating a fruity odor on the breath. The main cause of DKA is not enough insulin. A lack of insulin means sugar can’t get into your cells. Your cells need sugar for energy. This causes your body’s glucose levels to rise. To get energy, the body starts to burn fat. This process causes ketones to build up. Ketones can poison the body. High blood glucose levels can also cause you to urinate often. This leads to a lack of fluids in the body (dehydration). DKA can be caused by missing an insulin dose, eating poorly, or feeling stressed. An infection or other illness (such as pneumonia or a urinary tract infection) can also lead to DKA. If you have signs of infection (fever, cough, or sore throat), contact your doctor. You will want to make sure you are getting the right treatment. For some people, DKA may be the first sign that they have diabetes. When you are sick, you need to watch your blood sugar level very closely so that it doesn’t get too high or too low. Ask your doctor what your critical blood sugar level is. Most patients should watch their glucose levels c Continue reading >>
Diabetic Ketoacidosis ?
I am a type 1 diabetic and I have a problem that I cant seem to figure out. I have an appointment with my doctor in about a month, because they cant get me in any earlier. But what happens is I get really sick to my stomach, my blood sugar usually drops EXTREMELY fast, I get dizzy, a headache, and I always seem to yawn a lot. I have some ideas about what it might be, like ketoacidosis. But I am not entirely sure. Do you have any ideas? I would suggest that you go to your local drug store and obtain a canister of ketosticks. Check your urine for ketone. It is a very simple test. This will tell if you have ketonuria. If this is the case it is important that you see a doctor immediately. Call you doctor and tell them what is happening and you need help very quickly. If your doctor does not see you, go to an emergency room. This is a very serious situation. Take care, Wanda QUOTE posted on the "about portions'' thread: "The presence of ketones is called "ketonuria," and further dehydration and ketone build-up can result in ketoacidosis which is a medical emergency. The bottom line is that the presence of ketones in someone with type 1 diabetes shows a dangerous lack of insulin and the immediate need for more insulin. Exercise, at this time, will only burn more fat and produce more ketones. " (+ info) diabetic ketoacidosis? if you die of diabetic ketoacidosis are there warning signs before you die and when does it alert your body? and is this something that just happens to some one or is it due to the fact of foul play by the person or someone else. how is foul pay involved. if you die at the age of 40 is it required for an autopsy to be preformed There are major warning signs if diabetic ketoacidosis (DKA). Once the DKA is advanced the diabetic will vomit everything he or s Continue reading >>
A Preventable Crisis People who have had diabetic ketoacidosis, or DKA, will tell you it’s worse than any flu they’ve ever had, describing an overwhelming feeling of lethargy, unquenchable thirst, and unrelenting vomiting. “It’s sort of like having molasses for blood,” says George. “Everything moves so slow, the mouth can feel so dry, and there is a cloud over your head. Just before diagnosis, when I was in high school, I would get out of a class and go to the bathroom to pee for about 10–12 minutes. Then I would head to the water fountain and begin drinking water for minutes at a time, usually until well after the next class had begun.” George, generally an upbeat person, said that while he has experienced varying degrees of DKA in his 40 years or so of having diabetes, “…at its worst, there is one reprieve from its ill feeling: Unfortunately, that is a coma.” But DKA can be more than a feeling of extreme discomfort, and it can result in more than a coma. “It has the potential to kill,” says Richard Hellman, MD, past president of the American Association of Clinical Endocrinologists. “DKA is a medical emergency. It’s the biggest medical emergency related to diabetes. It’s also the most likely time for a child with diabetes to die.” DKA occurs when there is not enough insulin in the body, resulting in high blood glucose; the person is dehydrated; and too many ketones are present in the bloodstream, making it acidic. The initial insulin deficit is most often caused by the onset of diabetes, by an illness or infection, or by not taking insulin when it is needed. Ketones are your brain’s “second-best fuel,” Hellman says, with glucose being number one. If you don’t have enough glucose in your cells to supply energy to your brain, yo Continue reading >>
Viewer Comments: Diabetic Ketoacidosis - Symptoms
I didn't know anything about diabetic ketoacidosis (DKA) until I was admitted into the ICU. Learning about DKA now, I've had moderate DKA on and off for years. I thought my vomiting, stomach pain were the result of metformin and switched to Invokana. I experienced extreme weight loss and dehydration but thought these were normal (Invokana shown to help diabetics lose weight). I have been under extreme financial and emotional stress for the past few years as well. What I would want others to know is that it is difficult to identify DKA from medication side effects; until DKA is at the ICU level. I was given so much potassium and other electrolytes. Stress is also a huge factor for me. While in the ICU my ex-husband (knowing I was in the ICU) started more harassment. The nurses documented an over 100 jump in my blood sugar after a phone call to deal with the harassment. I've started tracking stress and my blood sugar. It is impossible to get control of my blood sugar during high stress. If I add more insulin, I have a dangerous crash later. Keeping a calm environment as much as I can helps. I have type 2 diabetes. I gave myself more than 300 shots. My doctor put me on metformin. This takes the place of insulin shots. There are three different doses. What made it for me was 850 mg per meal. I count my carbohydrates, 60 per meal, and take my pill. I have seen here, folks that have 200, 300, 695 mg/dl of glucose. It is tough to manage, but if you keep to it, you will do well. Check the bottoms of your feet daily. If you are ticklish, you are doing fine. Give up cakes, pies, ice cream and other things high in carbohydrates. If you do, you will be fine. By the way, my average glucose reading is less than 120. Set that as your goal. Have good days! I have been having really dif Continue reading >>
Doctor, You Aren’t Listening To Me... What If I Do Nothing?
A month ago my sister wanted to know if her Jack Russell Terrier could be sick because he was drinking and peeing all the time. I told her he needed to go to the vet; he could have a simple urinary tract infection or he could have more going on. Inside my head, I was screaming “diabetes” as polyuria/polydipsia (drinks a lot and pees a lot), or PU/PD as medical types call it, is a hallmark for diabetes mellitus in dogs, cats, and people. In dogs, diabetes mellitus rarely responds to dietary changes - unlike some people and some cats - and almost always requires twice daily insulin injections to control the disease. Having seen clients react to a diagnosis of diabetes, I wondered how my sister and her husband would react if they had to take care of this chronic condition that requires significant planning and scheduling. It’s not for every owner: while it’s not expensive, it requires insulin injections every 12 hours, 7 days a week for the rest of the pet’s life, with no time off for good behavior. It requires considerable commitment, which can be particularly difficult for people like my sister and her husband who work outside the home and can’t drop everything to give a pet medication at the appropriate times. I wondered what they would choose to do if their dog did have diabetes rather than a urinary tract infection. Receiving a diagnosis of a chronic disease can be difficult to wrap your mind around. During my years in practice, I noticed that there are some pretty universal questions most clients ask. “What are my options and what will happen if I do nothing?” When I hear this, I translate this into: a. How will the disease progress? Will this be a disease that progresses quickly or is it going to be something that is a nagging problem for years to co Continue reading >>
Patient professional reference Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find the Pre-diabetes (Impaired Glucose Tolerance) article more useful, or one of our other health articles. See also the separate Childhood Ketoacidosis article. Diabetic ketoacidosis (DKA) is a medical emergency with a significant morbidity and mortality. It should be diagnosed promptly and managed intensively. DKA is characterised by hyperglycaemia, acidosis and ketonaemia: Ketonaemia (3 mmol/L and over), or significant ketonuria (more than 2+ on standard urine sticks). Blood glucose over 11 mmol/L or known diabetes mellitus (the degree of hyperglycaemia is not a reliable indicator of DKA and the blood glucose may rarely be normal or only slightly elevated in DKA). Bicarbonate below 15 mmol/L and/or venous pH less than 7.3. However, hyperglycaemia may not always be present and low blood ketone levels (<3 mmol/L) do not always exclude DKA. Epidemiology DKA is normally seen in people with type 1 diabetes. Data from the UK National Diabetes Audit show a crude one-year incidence of 3.6% among people with type 1 diabetes. In the UK nearly 4% of people with type 1 diabetes experience DKA each year. About 6% of cases of DKA occur in adults newly presenting with type 1 diabetes. About 8% of episodes occur in hospital patients who did not primarily present with DKA. However, DKA may also occur in people with type 2 diabetes, although people with type 2 diabetes are much more likely to have a hyperosmolar hyperglycaemic state. Ketosis-prone type 2 diabetes tends to be more common in older, overweight, non-white people with type 2 diabetes, and DKA may be their Continue reading >>
The Scary Experience Of Diabetic Ketoacidosis
Today, we’re excited to share with you another guest blog from Katie Janowiak, who works for the Medtronic Foundation, our company’s philanthropic arm. When she first told me her story about food poisoning and Diabetic Ketoacidosis (DKA), I knew others could benefit from hearing it as well. Thanks Katie for your openness and allowing us to share your scary story so that the LOOP community can learn from it. Throughout this past year, I’ve had the honor of sharing with you, the amazing LOOP community, my personal journey and the often humorous sequence of events that is my life with T1. Humor is, after all, the best (and cheapest) therapy. Allow me to pause today to share with you the down and dirty of what it feels like to have something that is not the slightest bit humorous: diabetic ketoacidosis.You are hot. You are freezing. You are confused. You are blacked out but coherent. You go to talk but words fail you. Time flies and goes in slow motion simultaneously. You will likely smell and look like death. In my instance, this was brought on by the combination of excessive vomiting and dehydration caused by food poisoning and the diabetic ketoacidosis that followed after my body had gone through so much. In hindsight, I was lucky, my husband knew that I had food poisoning because I began vomiting after our meal. But I had never prepped him on diabetic ketoacidosis and the symptoms (because DKA was for those other diabetics.) Upon finding me in our living room with a bowl of blood and bile by my side (no, I am not exaggerating), he got me into the car and took me to emergency care. It was 5:30 p.m. – and I thought it was 11:00 a.m. The series of events that led up to my stay in the ICU began innocently enough. It was a warm summer night and my husband and I walke Continue reading >>
's Experience With Ketoacidosis.
Signs Treatment Zama's experience Diabetic ketoacidosis is caused by a lack of insulin or an insufficient amount of insulin. Since the lack of insulin means that glucose in not able to be used, the body searches for a new source of energy. In this condition, the diabetic breaks down body fat (lipolysis) to use as energy. During lipolysis, waste products called ketones are produced. Ketones are eliminated in the urine and through the lungs. Under normal conditions, the body can tolerate and eliminate ketones. But in diabetic ketoacidosis, fats are being broken down at such a high rate that the body can not eliminate the ketones fast enough and they build up in the blood. In high amounts, ketones are toxic to the body. They cause the acid-base balance to change and serious electrolyte and fluid imbalances result. Some of the signs of ketoacidosis include polyuria polydipsia lethargy anorexia weakness vomiting dehydration There will probably be ketones in the urine (ketonuria) The breath may have a sweet chemical smell similar to nail polish remover. However, some owners have said that even during documented ketoacidosis, their pet's breath did NOT have any unusual odor. Treatment Mildly ketoacidotic animals can be alert and well hydrated. After your pet is stabilized, your pet can return home and be treated with proper diabetes management techniques including insulin therapy, diet, and exercise. "Sick" ketoacidotic animals require intensive medical management in the vet hospital. This is a life-threatening emergency that requires complex medical management and monitoring. It may take several days for the animal to be out of danger. Treatment involves injections of regular insulin, intravenous fluids, electrolytes, and frequent monitoring of blood glucose, blood chemistry, Continue reading >>
‘i Was 26 And Most Type 1 Diabetics Are Diagnosed In Childhood': The Deadly Danger Too Many Diabetics Aren't Warned About
Hannah Postles discovered she had type 1 diabetes after going to A&E with blurred vision. It wasn’t her only symptom. For the previous three weeks, she’d been thirsty, drinking two bottles of water at lunch, had lost weight and felt run down. Scroll down for video ‘My boss suggested I might have diabetes after looking up my symptoms online, but my GP seemed to dismiss it because of my age,’ says Hannah, a press officer for the University of Sheffield. ‘I was 26 and most type 1 diabetics are diagnosed in childhood.’ Luckily, Hannah spoke to a doctor friend who told her to go to A&E, where she was tested for diabetes, and immediately put on an insulin drip. Type 1 diabetes occurs when the body doesn’t make insulin, the hormone that regulates glucose levels in the blood. Typically, people with type 1 diabetes are diagnosed around the age of 12 — although occasionally adults are diagnosed in later life. Type 2 diabetes, which can be diagnosed at any age, occurs when the body doesn’t produce enough insulin, or the insulin itself does not work properly. Not only did Hannah have diabetes, her blood sugar levels were so out of control by the time she was diagnosed that she had developed diabetic ketoacidosis, a life-threatening condition when blood glucose levels remain persistently high for days or weeks. The condition can be caused by illness or infection or by the mismanagement of diabetes — which, as Hannah, now 29, discovered, can be the result of not knowing you have it. Symptoms include vomiting, headaches, abdominal pain and, if left too long, coma and even death. Had Hannah not gone to A&E, she might have died. In July 2012, new mother Nicky Rigby, 26, from the Wirral, did die from undiagnosed type 1 diabetes. She’d assumed her chronic tiredness a Continue reading >>