How Does The Liver Store Glucose?

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In this video we discuss what is homeostasis and why it is important for health. We also cover what is set point, and cover how homeostasis uses it to keep a stable internal environment. What is homeostasis? To be brief and to the point, homeostasis is the relatively constant state maintained by the body. Mainly this means that over time, the internal body will maintain a stable environment. So, for example, if the external temperature is cold or hot, the internal body temperature will remain relatively constant at 98.6f or 37c, the internal body temp may vary a little above or below this number, but that will still be normal. So, lets say we took someones body temperature over a certain time period. If we plot that on a chart it may look something like this. Here, body temperature rose slightly, and here it fell a little. But, the normal body temperature range is from 97.7 to 99.5. So, our subject was inside the normal range throughout the time span. Homeostasis doesnt just apply to body temperature, but many other conditions as well. The human body needs to maintain a certain range of nutrients in the blood stream, such as water, glucose, salt, and other elements as well. We get

Quantifying The Contribution Of The Liver To Glucose Homeostasis: A Detailed Kinetic Model Of Human Hepatic Glucose Metabolism

Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism Affiliation Institute of Biochemistry, University Medicine Charit Berlin, Berlin, Germany Affiliation Institute of Biochemistry, University Medicine Charit Berlin, Berlin, Germany Affiliation Institute of Biochemistry, University Medicine Charit Berlin, Berlin, Germany Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism Despite the crucial role of the liver in glucose homeostasis, a detailed mathematical model of human hepatic glucose metabolism is lacking so far. Here we present a detailed kinetic model of glycolysis, gluconeogenesis and glycogen metabolism in human hepatocytes integrated with the hormonal control of these pathways by insulin, glucagon and epinephrine. Model simulations are in good agreement with experimental data on (i) the quantitative contributions of glycolysis, gluconeogenesis, and glycogen metabolism to hepatic glucose production and hepatic glucose utilization under varying physiological states. (ii) the time courses of postprandial glycogen storage as well Continue reading >>

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  1. TriLifter

    So, I'm wondering if this is fat-adapted related? The past few months my urine has smelled weird. Like asparagus pee, but without eating asparagus. I mean, I HAVE eaten asparagus, but not every day LMAO.
    Anyway, I'm just wondering if the strong odor has something to do with being paleo. My carbs are relatively high (65-85g/day) and my breath smells fine (believe my, my husband would tell me if it didn't). My urine used to not really smell like anything, but now it does, even when almost clear from my excessive water intake.

  2. justaspoonfulofsugar

    This is due to ketosis..I have it as well..I also often have to deal with metal mouth and brush my teeth all the time.
    Not everyone has to be below 50 grams to be in ketosis..for some it comes with less than 80 grams

  3. TriLifter

    Thank you! I didn't want to throw the k-word (ketosis) around too frivilously. I'm glad that's what it sounds like--that's what I was hoping. It's kinda of embarrassing to pee at work, though, because I know people in other stalls can probably smell it too!

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Molar Mass Grams/Mol Grams per mol Molar Mass Grams/Mol Grams per mol Molar Mass Grams/Mol Grams per mol Molar Mass Grams/Mol Grams per mol

Four Grams Of Glucose

Department of Molecular Physiology and Biophysics and Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee Department of Molecular Physiology and Biophysics and Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee Address for reprint requests and other correspondence: D. H. Wasserman, Light Hall Rm. 702, Vanderbilt Univ. School of Medicine, Nashville, TN 37232 (e-mail: [email protected] ) Received 2008 Jul 7; Accepted 2008 Oct 1. Copyright 2009, American Physiological Society This article has been cited by other articles in PMC. Four grams of glucose circulates in the blood of a person weighing 70 kg. This glucose is critical for normal function in many cell types. In accordance with the importance of these 4 g of glucose, a sophisticated control system is in place to maintain blood glucose constant. Our focus has been on the mechanisms by which the flux of glucose from liver to blood and from blood to skeletal muscle is regulated. The body has a remarkable capacity to satisfy the nutritional need for glucose, while still maintaining blood glucose homeostasis. The essential rol Continue reading >>

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  1. solstice

    So I used a ketone strip after working out Saturday and it turned a bright scarlet. I was very pleased with my progress. How often should I check and what color should the strip be? I am starting to drive myself a little crazy by checking it a lot.

  2. SugarFluff

    You don't have to check ever. When I used to use those strips I'd test daily, usually in the morning. Anything other than the neurtal shade means you're in ketosis. You're likely dehydrated if the deep, dark colors show up.

  3. MandyGa

    I bought soem strips and checked it almost every time I went but now that im down to less than 5 strips I 've slowed down.....(i hate paying 12 bucks for some strips I pee on). Mine turn a really dark purple. I know I dont drink enough water but I/m trying

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Entry for Berkeley's Navigating the Gray Engineering Video Contest. Made Possible with the Information Provided by the Following Websites: http://www.globalresearch.ca http://www.nongmoproject.org http://www.actionbioscience.org http://www.scu.edu http://www.responsibletechnology.org http://www.gmfreecymru.org http://www.ncbi.nlm.nih.gov http://www.elsevier.com http://www.sciencebasedmedicine.org http://www.randi.org http://www.monsanto.com http://www.nspe.org Songs used under a creative commons license. A Very Special Thanks to Brittney Duquette and Jodie Howard

How Our Bodies Turn Food Into Energy

All parts of the body (muscles, brain, heart, and liver) need energy to work. This energy comes from the food we eat. Our bodies digest the food we eat by mixing it with fluids (acids and enzymes) in the stomach. When the stomach digests food, the carbohydrate (sugars and starches) in the food breaks down into another type of sugar, called glucose. The stomach and small intestines absorb the glucose and then release it into the bloodstream. Once in the bloodstream, glucose can be used immediately for energy or stored in our bodies, to be used later. However, our bodies need insulin in order to use or store glucose for energy. Without insulin, glucose stays in the bloodstream, keeping blood sugar levels high. Insulin is a hormone made by beta cells in the pancreas. Beta cells are very sensitive to the amount of glucose in the bloodstream. Normally beta cells check the blood's glucose level every few seconds and sense when they need to speed up or slow down the amount of insulin they're making and releasing. When someone eats something high in carbohydrates, like a piece of bread, the glucose level in the blood rises and the beta cells trigger the pancreas to release more insulin in Continue reading >>

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  1. AK330

    Hello folks, I'm actually doing a lot of research before making the jump to this diet. A little bit of background though, I'm a male, 6'2" ~185lb now, around 18-20% BF. I've cut about 15lb naturally with lifting/cardio and reducing sweets significantly in my current diet (for about a year now). I'm still latched onto a few processed foods though, which mostly are in the carb spectrum. I've cut my alcohol consumption to about 1-2 days a month over the past few months as well.
    But....I also cut caffeine out completely the last 2 months (including the tricky sources like chocolate). Doing so has allowed me to see the ups and downs of carb consumption, which is inherently why I am gravitating to this diet. Most of my supposed energy before has been dictated by caffeine use, and since dropping that I've been quite content with not going back to caffeine at all (even decaff, as that does contain caffeine...yes I absolutely DO research before I make any diet choice). I'm just wondering if there is a good alternative to the bulletproof coffee, I was considering a bulletproof bouillon mix instead (to compensate for electrolytes). I would consider going back to caffeine if it is necessary, but I would have to move my workouts into early mornings (and I'm notoriously not a morning person, although this diet could change that depending on my energy levels) as caffeine in the afternoon affects my sleep.
    I guess my main question would be if there is an inherent "crash" from caffeine on a strict keto diet, with just a single cup of coffee, and any inherent caffeine withdrawal symptoms as well. I mostly intend to do this before a workout so I don't intend to consume caffeine on off days (hence the caffeine withdrawal issues).

  2. anbeav

    BPC is not required for keto, so I wouldn't start drinking caffeine just for BPC
    The crash and withdrawal are highly individual

  3. AK330

    I understand it isn't required, I'm just looking for a decent high fat drink to consume preferably before a workout. I'm probably just going to throw in coconut/mct and butter into a bouillon drink.

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