BGS Global Hospital performs successful Liver Transplant to treat Acute Liver Failure Karnatakas largest liver transplant program clocks in 140 liver transplants till date Bangalore, December 7, 2016: BGS Global Hospital, a part of Parkway Pantai,successfully performed a liver transplant saving the life of a 51-year-old patient from Bangalore suffering from acute liver failure caused by anti-tuberculosis medication. His condition was fast deteriorating when he arrived at the hospital. Acute liver failure is loss of liver function that occurs rapidly in days or weeks in a person who has no pre-existing liver disease. It is much less common compared to other liver diseases requiring liver transplantation, such as decompensated cirrhosis of the liver, which develops more slowly. Acute liver failurecauses serious complications, including excessive bleeding and increasing pressure on the brain. Other organs like the heart, lungs and kidneys may also require support in such patients. It is a medical emergency that requires intensive care, ideally in transplant centres. Depending on the cause, acute liver failure can sometimes be reversed with medical treatment. In many situations, tho
Liver Failure, Acute
These correspond to diseases that can cause LFTs in the 1000s, which actually carries a fairly limited differential diagnosis: Acetaminophen - accounts for the majority of cases in the US. Other drugs/toxins including isoniazid, antibiotics, anticonvulsants, PTU, and poison mushrooms. Importantly, alcohol does not really cause LFTs in the 1000s nor does it cause acute liver failure!!! Hep B > Hep A, not really Hep C. Also Hep D (with Hep B coinfection) and Hep E (esp pregnant women). Rarely, other viruses such as HSV, CMV, adenovirus, and others can cause ALF especially in immunocompromised patients. 3. Vascular: "Shock liver" from extreme hypotension, Budd-Chiari, Veno-occlusive disease Wilson's Disease - accounts for 2-3% of ALF - presents usually in young adults with hemolytic anemia and acute liver failure, often with characteristically low Alk Phos. Other metabolic causes include complications related to pregnancy - Acute Fatty Liver of Pregnancy and HELLP syndrome. Reye's syndrome - associated with children taking ASA while suffering from viral illness (influenza, varicella). 5. Autoimmune Hepatitis - often is the first presentation, can be fulminant. Overview of ALF Manifes
What is HEART FAILURE? What does HEART FAILURE mean? HEART FAILURE meaning & explanation. Heart failure (HF), often referred to as congestive heart failure (CHF), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs. Signs and symptoms commonly include shortness of breath, excessive tiredness, and leg swelling. The shortness of breath is usually worse with exercise, while lying down, and may wake the person at night. A limited ability to exercise is also a common feature. Chest pain, including angina, does not typically occur due to heart failure. Common causes of heart failure include coronary artery disease including a previous myocardial infarction (heart attack), high blood pressure, atrial fibrillation, valvular heart disease, excess alcohol use, infection, and cardiomyopathy of an unknown cause. These cause heart failure by changing either the structure or the functioning of the heart. There are two main types of heart failure: heart failure due to left ventricular dysfunction and heart failure with normal ejection fraction depending on whether the ability of the left ventricle to contract is affected, or the heart's ability to
Fulminant Hepatic Failure
markedly increased susceptibility to bacterial infections (bacteraemia in 30%, fungaemia in 10%) significantly more common in patients with renal failure. respiratory (47%) or urinary tract origin most common Gram +ve most common in first week, gram -ve in second week and fungal infection in third week ECG: multiple VEs, heart block, bradycardia common EEG: hepatic encephalopathy has characteristic pattern HAV IgM, HBcAb (IgM) - high sensitivity and specificity for acute infection with these 2 viruses. Assay for antibody to hepatitis C not very useful as it is rarely positive in the acute stages of the disease. Usually becomes positive for the first time only 3-6 months after the onset. The presence of HB IgM Ab to core Ag usually required for diagnosis as surface antigen is rapidly cleared lamivudine for patients with hepatitis B treated with steroids (to prevent acute liver failure on withdrawal of steroids) NB Early liason with and transfer to specialist unit before patient develops grade IV coma. 90% ofpatients in grade III coma progress to grade IV. N-acetylcysteine of benefit in patients following paracetamol overdose evenwhen there is evidence of encephalopathy and coagulop
VISIT: http://livercirrhosis.vital101.com How To Cure Liver Cirrhosis Naturally - Liver Cirrhosis Natural Treatment - Liver Cirrhosis Diet What is cirrhosis of the liver? Cirrhosis is a condition that results from permanent damage or scarring of the liver. This leads to a blockage of blood flow through the liver and prevents normal metabolic and regulatory processes. What are the major causes of cirrhosis? The major causes of cirrhosis are as follows: - Chronic alcoholism. - Viral infections caused by chronic viral hepatitis (types B, C and D). - Metabolic diseases such as alpha-1-antitrypsin deficiency, galactosemia and glycogen storage disorders. - inherited diseases such as Wilson disease and hemochromatosis. - Biliary cirrhosis resulting from diseases such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). - Toxic hepatitis caused by severe reactions to prescribed drugs or prolonged exposure to environmental toxins. - repeated bouts of heart failure with liver congestion. What are some early symptoms of cirrhosis? People in the early stages of cirrhosis have few symptoms. Some symptoms an individual may notice include: - Loss Of Appetite. - Nausea. -
Alterations In Arterial Blood Parameters In Patients With Liver Cirrhosis And Ascites
Int J Med Sci 2007; 4(2):94-97. doi:10.7150/ijms.4.94 Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis and Ascites Konstantinos Charalabopoulos1,2, Dimitrios Peschos3, Leonidas Zoganas4, George Bablekos4, Christos Golias1, Alexander Charalabopoulos1, Dimitrios Stagikas1, Angi Karakosta1, Athanasios Papathanasopoulos5, George Karachalios2, Anna Batistatou3 1. Department of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece. 2. Department of Medicine, Red Cross Hospital, Athens, Greece. 3. Department of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece. 4. Department of Thoracic Surgery, Red Cross Hospital, Athens, Greece. 5. Department of Medicine, Gastroenterology Unit, Medical Faculty, University of Ioannina, Ioannina, Greece. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License . See for full terms and conditions. Charalabopoulos K, Peschos D, Zoganas L, Bablekos G, Golias C, Charalabopoulos A, Stagikas D, Karakosta A, Papathanasopoulos A, Karachalios G, Batistatou A. Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis a
Why Does Renal Failure Cause Metabolic Acidosis Renal failure patients will have many symptoms and discomforts among which metabolic acidosis, water and electrolytes disorders are the most common. Metabolic acidosis is due to excessive accumulation of acidic substances in the blood due to diminished renal filtering functions. Metabolic acidosis can cause the patients to have the following clinical symptoms such as loss of appetite, nausea, vomit ...
Practice Essentials Metabolic acidosis is a clinical disturbance characterized by an increase in plasma acidity. Metabolic acidosis should be considered a sign of an underlying disease process. Identification of this underlying condition is essential to initiate appropriate therapy. (See Etiology, DDx, Workup, and Treatment.) Understanding the regulation of acid-base balance requires appreciation of the fundamental definitions and principles unde ...
Lactic acidosis is a medical condition characterized by the buildup of lactate (especially L-lactate) in the body, which results in an excessively low pH in the bloodstream. It is a form of metabolic acidosis, in which excessive acid accumulates due to a problem with the body's metabolism of lactic acid. Lactic acidosis is typically the result of an underlying acute or chronic medical condition, medication, or poisoning. The symptoms are generall ...
Metabolic Acidosis and Progression of Chronic Kidney Disease Department of Medicine, University of California San Francisco, San Francisco, California The concentration of hydrogen ion is normally managed by several buffering and elimination systems, including the kidney. Consequently, progressive renal failure is accompanied by an increasing inability to excrete metabolites of fuel consumption, lower blood pH, and reduced plasma bicarbonate lev ...
Metabolic acidosis can occur in both acute and chronic renal disorders the anion gap may be elevated, due to uraemic acidosis the anion gap may be normal, due to renal tubular acidosis (RTA) Uraemic acidosis results from the loss of functional nephrons decreased glomerular filtration rate (GFR) (e.g. <20 mL/min) accumulation of acidic anions such as phosphate and sulfate occurs causes high anion gap metabolic acidosis (HAGMA) patients manifest a ...
Respiratory AlkalosisDifferential Diagnoses Author: Ryland P Byrd, Jr, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP more... Hyperthyroidism: Hyperthyroidism increases the ventilation chemoreflexes, thereby causing hyperventilation. These chemoreflexes return to normal with treatment of the hyperthyroidism. Pregnancy: Progesterone levels are increased during pregnancy. Progesterone causes stimulation of the respiratory center, which can lead t ...