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How Does Diabetic Ketoacidosis Cause Metabolic Acidosis?

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What is ALKALOSIS? What does ALKALOSIS mean? ALKALOSIS meaning - ALKALOSIS pronunciation - ALKALOSIS definition - ALKALOSIS explanation - How to pronounce ALKALOSIS? Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Alkalosis is the result of a process reducing hydrogen ion concentration of arterial blood plasma (alkalemia). In contrast to acidemia (serum pH 7.35 or lower), alkalemia occurs when the serum pH is higher than normal (7.45 or higher). Alkalosis is usually divided into the categories of respiratory alkalosis and metabolic alkalosis or a combined respiratory/metabolic alkalosis. Respiratory alkalosis is caused by hyperventilation, resulting in a loss of carbon dioxide. Compensatory mechanisms for this would include increased dissociation of the carbonic acid buffering intermediate into hydrogen ions, and the related excretion of bicarbonate, both of which lower blood pH. Hyperventilation-induced alkalosis can be seen in several deadly central nervous system diseases such as strokes or Rett syndrome. Metabolic alkalosis can be caused by rep

Acidosis-induced Hypochloremic Alkalosis In Diabetic Ketoacidosis Confirmed By The Modified Base Excess Method

The Journal of Clinical Endocrinology & Metabolism Acidosis-Induced Hypochloremic Alkalosis in Diabetic Ketoacidosis Confirmed by The Modified Base Excess Method Department of Endocrinology and Internal Medicine, Matsunami General Hospital, Gifu 501-6062, Japan Address all correspondence and requests for reprints to: Keigo Yasuda, MD, PhD, Department of Endocrinology and Internal Medicine, Matsunami General Hospital, 185-1 Dendai, Kasamatsu, Gifu 501-6062, Japan. Search for other works by this author on: Department of Endocrinology and Internal Medicine, Matsunami General Hospital, Gifu 501-6062, Japan Search for other works by this author on: Department of Endocrinology and Internal Medicine, Matsunami General Hospital, Gifu 501-6062, Japan Search for other works by this author on: Department of Endocrinology and Internal Medicine, Matsunami General Hospital, Gifu 501-6062, Japan Search for other works by this author on: The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 6, 1 June 2016, Pages 23902395, Keigo Yasuda, Makoto Hayashi, Masanori Murayama, Noriyoshi Yamakita; Acidosis-Induced Hypochloremic Alkalosis in Diabetic Ketoacidosis Confirmed by The Modified Continue reading >>

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  1. Spazzomatic

    Two things I'd like to mention first:
    - I THOUGHT I was getting my "monthly friend" but have yet to, so the weight gain could be water weight ALTHOUGH I took a water pill (furosemide) and it didn't help!
    - I was advised as follows:
    I started a Paleo diet at the beginning of January with no problems. I lost ten pounds, but was told that it was probably water weight. I expressed interest in Keto, and was told (after a look at my MFP diary) that I needed to eat more calories. I am 5'1 and 219 lbs (I was 215 before I attempted Keto earlier this week).
    He suggested I eat between 1200-1600 cal./day and add dairy back into my diet. I ate the 1200 as it was a lot of food, but then when I began to feel the weight stick on, and increase, I read that a DEFICIT is still important, EVEN ON KETO!
    This gentleman told me that all that matters is that I hit my calorie mark, hit my macros and stay away from fruit (which I have not touched since switching!)
    So my daily calories intake was suggested by a keto calculator to be 1,059/day. I have gained FOUR pounds and feel like all the weight I lost around my mid section has come back.
    If you could look at my diary, or perhaps tell me what I THINK I already know - the dairy is stalling/making me gain weight, OR that I AM getting my monthly friend and it's just water weight. I'm so confused, I start school tomorrow and all the weight loss is gone Please help me, THANK YOU IN ADVANCE!!!!!

  2. Nasheajones

    I know how frustrating it can be to not see the scale moving in the right direction! I have had weeks where my weight fluctuates by seven pounds from Monday to Friday. Somedays it will look like I gained 5 pounds overnight! If you stick to it and drink plenty of water you will see the scale go down. I have noticed every weekend it looks like I have gained and I do not eat any more on the weekends however I do not drink much water for some reason and it make the scale go up temporarily.
    I looked at several days in your food diary and it seemed good to me. I would just give it a little more time for your body to adapt to the changes.
    Hope someone with more experience chimes in with good advice!
    Take care

  3. Spazzomatic

    I know how frustrating it can be to not see the scale moving in the right direction! I have had weeks where my weight fluctuates by seven pounds from Monday to Friday. Somedays it will look like I gained 5 pounds overnight! If you stick to it and drink plenty of water you will see the scale go down. I have noticed every weekend it looks like I have gained and I do not eat any more on the weekends however I do not drink much water for some reason and it make the scale go up temporarily.
    I looked at several days in your food diary and it seemed good to me. I would just give it a little more time for your body to adapt to the changes.
    Hope someone with more experience chimes in with good advice!
    Take care
    Oh thank you so much for the encouraging words, I am so depressed I feel as though perhaps adding the dairy in was a poor idea, as I started gaining weight shortly after that. I think I will tweak the dairy down to just butter and see how it goes. Good luck to you as well, and thank you again!

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Diabetic Ketoacidosis

Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP more... Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that mainly occurs in patients with type 1 diabetes, but it is not uncommon in some patients with type 2 diabetes. This condition is a complex disordered metabolic state characterized by hyperglycemia, ketoacidosis, and ketonuria. The most common early symptoms of DKA are the insidious increase in polydipsia and polyuria. The following are other signs and symptoms of DKA: Malaise, generalized weakness, and fatigability Nausea and vomiting; may be associated with diffuse abdominal pain, decreased appetite, and anorexia Rapid weight loss in patients newly diagnosed with type 1 diabetes History of failure to comply with insulin therapy or missed insulin injections due to vomiting or psychological reasons or history of mechanical failure of insulin infusion pump Altered consciousness (eg, mild disorientation, confusion); frank coma is uncommon but may occur when the condition is neglected or with severe dehydration/acidosis Signs and symptoms of DKA associated with possible intercurrent infection are as follows: Gl Continue reading >>

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  1. teamzissous

    I made a post a little while back about having consistent bladder and or kidney pains whenever I was in ketosis. It took a while to correlate the pain with low carb (originally thought I may have a hernia, even a doctor thought so and ordered a CT scan, found nothing and gave up on me)
    One redditor (THANK YOU SoftwareMaven) suggested an acidic urine pH. After charting my pain and testing my urine with rapid response urinalysis strips I found that my urine was much too acidic, and it correlated with the pain.
    Apparently ketones tend to make your urine more acidic and you HAVE to balance out your protein/meat intake with alkalizing vegetables (fruits really help too) I've been following the PRAL food lists in order to help keep my urine more alkaline.
    It was also suggested that I try adding some baking soda (sodium bicarbonate) to some water if I was eating a particularly acidic forming meal, and IT WORKS!
    There are also some supplementary benefits of baking soda according to examine.com, it has the same benefits of supplementing with beta alanine (reduces muscle burn when taken 60-90 min before a workout) They also note that a study has shown it has no significant effect on your blood pressure, good to know.
    note: I make a point to drink a TON of water, but it is not sufficient to balance out my urine pH.
    TL;DR Thank you SoftwareMaven! Ketosis can make your urine too acidic causing kidney/bladder pain. Eat more alkalizing vegetables (and/or fruit). Also drinking baking soda and water with your acidic forming meal can also keep your pee balanced.

  2. emag

    It's interesting that acidic foods like lemon juice, orange juice, tomatoes, and vinegar all exert a base effect...

  3. happee

    What about coffee? It's pretty acidic, would it exert a base effect as well?

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What is KETOACIDOSIS? What does KETOACIDOSIS mean? KETOACIDOSIS meaning - KETOACIDOSIS definition - KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids. The two common ketones produced in humans are acetoacetic acid and ß-hydroxybutyrate. Ketoacidosis is a pathological metabolic state marked by extreme and uncontrolled ketosis. In ketoacidosis, the body fails to adequately regulate ketone production causing such a severe accumulation of keto acids that the pH of the blood is substantially decreased. In extreme cases ketoacidosis can be fatal. Ketoacidosis is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Prolonged alcoholism may lead to alcoholic ketoacidosis. Ketoacidosis can be smelled on a person's breath. This is due to acetone, a direct by-product of the sp

Ketoacidosis

Kamel S. Kamel MD, FRCPC, Mitchell L. Halperin MD, FRCPC, in Fluid, Electrolyte and Acid-Base Physiology (Fifth Edition), 2017 Introduction Although ketoacidosis is a form of metabolic acidosis because of the addition of acids, it is discussed separately in this chapter to emphasize the metabolic and biochemical issues required to understand the clinical aspects of this disorder (see margin note). We discuss the metabolic setting that is required to allow for the formation of ketoacids in the liver at a high rate and what sets the limit on the rate of production. Removal of ketoacids occurs mainly in the brain and kidneys. We examine what sets the limit on the rate of removal of ketoacids by these organs. We believe that understanding the biochemical and metabolic aspects of ketoacidsis provides the clinician with a better understanding of this disorder and allows for a better design of therapy in the individual patient with ketoacidosis. Relevant to the pathophysiology of this case, the soft drinks the patient consumed contained a large quantity of glucose, fructose, and caffeine. Ketoacids • A ketone is an organic compound that has a keto group (C=O) on an internal carbon atom. Continue reading >>

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  1. Scouser

    I started the Atkins diet at the beginning of the year and I am making slow progress. During the induction phase I lost 6 lb in this first week and then nothing after that. The second week I stayed the same weight and at time appeared to gain a pound or two and lose a pound or two! The whole time this was happening I was using the urine analysis strips ( and still am) and it was showing during the whole time I was producing a moderate to large amount of ketones! It has been a month now and I feel like I should be making more headway in this. Over the past month I have lost an additional four pounds (but I don't really count it because I have been known to put it on again some time in the week and then just stay at that weight). I have not increased my carbs from the inital amount suggested in the induction phase. I am concerned that I am not able to lose. I work out everyday (either yoga or step) for about 40 minutes, although I do have a desk job. Has this happened to anyone else? If so, what can I do?
    Thanks

  2. AngelaR

    It's normal to slow down after the induction period is over. Your body is thinking baout what is going on and trying to adjust. You are also exercising whish is replacing fat with lean muscle, and muscle weighs more than fat.
    Have you taken measurements? Sometimes you don't lose pounds, but you lose inches.
    The big question is, How much water are you drinking?
    Also, what are you eating? Are you eating any of the things that would slow you down? Are you eating foods that have hidden carbs? If you start a journal in the Bootcamp/Journals section, and post this kind of info regularly, then it will be easier for people to take a look at your patterns and give you some guidance.

  3. Natrushka

    Scouce, welcome to the forum.
    The first thing that comes to mind is are you drinking enough water and are you eating enough food. You should be drinking at the very minimum 64 oz of water a day (water, water and more water - anything else you drink should be above and beyond this). Guidlines for calories are 10 - 12 times your body weight a day - eating too little will stress your body and force it to hold onto fat and water. Put the two together and slow or nonexistant fat loss is not surprizing.
    Starting up a Journal in the Bootcamp section might be a good idea - just to give us some idea of what you've been eating and drinking. Remember to include quality and quantity! You might also be interested in checking out www.fitday.com It's a free online site that lets you keep track of fat/protein/carbs etc. It is usually a very eye opening experience.
    Hope to hear more,
    Nat

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