Re: Does Blood Ph Affect Heart Rate, And, If So, How?
Re: Does blood pH affect heart rate, and, if so, how? Posted By: Amit Agarwal, Grad student, Neuroscience/Neurogenetics, Dear Casey, Its indeed an interesting question, which still keeps manyscientific minds busy. Many researchers working in the field of cardiacbiology are trying to understand detailed electrophysiological andneurochemical mechanisms which can affect heart rate and its efficiency.There are several studies available on rodents which outline factorsresponsible for the maintenance of normal heart rate. Your question alsotargets one of the aspects of such studies. Several studies have shown thatacidosis can lead to reduced heart rate. So before going ahead letsunderstand what is acidosis? When breathing is restricted, the body cannot eliminate carbon dioxide asit should, and the amount of carbon dioxide in the blood increases. Carbondioxide (CO2) and water (H2O) exist in equilibrium with carbonic acid(H2CO3) in a reaction catalyzed by an enzyme called carbonic anhydrase.CO2 + H2O --> H2CO3 A molecule of carbonic acid dissociates on its own into a moleculebicarbonate (HCO3-) and an (acidic) hydrogen ion. (H+) H2CO3 <> HCO3- and H+ Thus the overall pattern is: H2O + CO2 Continue reading >>