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How Do Ketones Work

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Great article. You actually answered my question as to the ratio of the 3 BHB salts which is quite helpful for me. For me, I had Keto O/S and found it quite good – my favorite was the chocolate swirl. But it was and is very expensive. Only 15-20 servings and would break the bank. So I turned to KetoCaNa and I’ve tried two flavours. Both of them were so salty that I almost threw up every time. Like flavoured sea water. Also only 15 serving per bottle. Then I turned to Ketond which is okay – Tigers Blood and Caramel Macchiato. What I like about Ketond is that it has a full 30 servings and is very transparent with it’s ingredients. It’s also the same price as Keto OS but you get 30 servings. But still, not the best taste. So in the end, I ordered 1kg of pure BHB Magnesium from a supplier in China and I will be developing my own Ketone product with 30 servings as a lower price than all the competitors, and with more Magnesium, and Calcium in it than Sodium so that it tastes the best and actually helps with weight loss (which Magnesium is proven to do at the right amount). What the companies don’t tell you is that actually Sodium BHB is the cheapest, then Calcium BHB and then Magnesium BHB to source so I would be interested in knowing if what you wrote is actually true or just an excuse to make the product cheaper. Probably a mix of both. So I have 2 questions Ben: 1. If you had to split the 11.7g of BHB into Sodium, Ca, and Mg, what ratio would you do for the best health results and potential weight loss? The current products on the market are about an 80/12/8 split. I would think it should be the other way around. 2. When I develop my own product and sell it, would you be up for sampling it and reviewing it on your website here? What flavours do you like/would Continue reading >>

How Ketogenesis And Ketones Treat Inflammation

How Ketogenesis And Ketones Treat Inflammation

Intro Inflammation is a biological mechanism our bodies use to deal with internal and external events, such as combatting infections, repairing tissues or mitigating the immediate consequences of a fractured bone. However, it often carries a negative connotation since many diseases provoke symptoms through the process of inflammation. So although it is absolutely necessary for keeping the human body functioning properly, like so many things in biology, too much or too little is the problem. Inflammation can be managed with and without drugs. Here we will focus on ketogenesis and ketones with regards to treating inflammation since both drug and drug-free approaches can be discussed. What is ketogenesis? Ketogenesis is the process whereby your body produces molecules called ketone bodies, also known as ketones (see What’s a Ketone?). More specifically, ketogenesis is a series of biochemical reactions that builds molecules (ketones) from parts of other ones (like 2 acetyl-CoA molecules). How ketone bodies are formed? Fellow nerds can gaze upon the ketogenesis pathway below (1) whilst the non-initiated can simply keep in mind that our liver is ground-zero for ketogenesis. This is where fat is used as the raw material to produce 3 kinds of ketone bodies. Humans are remarkably good at ketogenesis. Just for comparison, dogs too can make ketones but the degree to which they require protein, carbohydrate or caloric restriction to do so is greater (2,3). Once you’ve produced enough ketones by upregulating ketogenesis, you eventually move into a metabolic state called ketosis. People are in ketosis when they are on a diet low enough in carbohydrates, known as a ketogenic diet, or when eating very very little if any food at all for example. What a ketogenic diet and fasting hav Continue reading >>

Ketone Bodies

Ketone Bodies

Ketone bodies Acetone Acetoacetic acid (R)-beta-Hydroxybutyric acid Ketone bodies are three water-soluble molecules (acetoacetate, beta-hydroxybutyrate, and their spontaneous breakdown product, acetone) that are produced by the liver from fatty acids[1] during periods of low food intake (fasting), carbohydrate restrictive diets, starvation, prolonged intense exercise,[2], alcoholism or in untreated (or inadequately treated) type 1 diabetes mellitus. These ketone bodies are readily picked up by the extra-hepatic tissues, and converted into acetyl-CoA which then enters the citric acid cycle and is oxidized in the mitochondria for energy.[3] In the brain, ketone bodies are also used to make acetyl-CoA into long-chain fatty acids. Ketone bodies are produced by the liver under the circumstances listed above (i.e. fasting, starving, low carbohydrate diets, prolonged exercise and untreated type 1 diabetes mellitus) as a result of intense gluconeogenesis, which is the production of glucose from non-carbohydrate sources (not including fatty acids).[1] They are therefore always released into the blood by the liver together with newly produced glucose, after the liver glycogen stores have been depleted (these glycogen stores are depleted after only 24 hours of fasting)[1]. When two acetyl-CoA molecules lose their -CoAs, (or Co-enzyme A groups) they can form a (covalent) dimer called acetoacetate. Beta-hydroxybutyrate is a reduced form of acetoacetate, in which the ketone group is converted into an alcohol (or hydroxyl) group (see illustration on the right). Both are 4-carbon molecules, that can readily be converted back into acetyl-CoA by most tissues of the body, with the notable exception of the liver. Acetone is the decarboxylated form of acetoacetate which cannot be converted Continue reading >>

What Can I Do To Become Smarter?

What Can I Do To Become Smarter?

I was the dumbest student in my class. I was the boy who would fail every subject. I couldn’t even read one page and understand what it meant All my school teachers predicted I would end up worthless, pointless and useless. And that is why I dropped out of school. My career started with jobs like a toilet cleaner and that of a sweeper and I was supposed to be mentally uneducable. But I had only one thing - Self Belief. And that lead me to start experimenting and finding ways how I could make my stupid useless brain ‘smarter’. So from communicating with dogs to seduction techniques to trying Brain Drugs - I made myself a guinea pig to find out - how I could hack into my senses. Today, people pay me $1,500 just for my advice only. And my students include Ph.D students, CEO’s & Directors. So I do not know what you can do to become smarter, but this is what I have done to make myself smarter. I hope you find these controversial or not usual techniques useful. But please be warned - not all of them are recommended. Please use them with caution and at your own risk. If you do find any useful, please share this article with someone you love or care Loy Machedo *********************** Try impressing a woman whom you have never met. The art and science of knowing different women will make you incredibly smart. If you are a man - Study women, observe them, think like them, make them like you, make them love you and make them want you. Women are complex creatures and to master this art - will really make you think. If you are a woman - look as attractive and seductive as possible go to places where there are many men (in a public place) and learn to handle men who cross the line, misbehave and treat you disrespectfully. Do not do it with a defensive or angry manner. Do it Continue reading >>

Pruvit Keto Os Review

Pruvit Keto Os Review

I'm Mike and I've been a personal trainer for over 10 years and I first heard about ketosis way back before it was even a big thing. I've been more or less on the ketogenic diet full-time ever since. When Keto-OS came out, people had been talking about Keto-OS being the go-to product for quickly getting into ketosis and even allowing you to cheat. Me being a skeptic, I set out on a 3 month strict review project, to get to the bottom of whether or not Keto-OS actually works. After months of testing blood samples and body calibrations, I am about to give you the conclusion of what I found from my review down below. KETO OS is the latest product from Pruvit and stands for "Ketone Operating System." This product is an exogenous ketone drink, which means it may provide a multitude of benefits, ranging from athletic performance enhancement, more efficient weight loss, cancer prevention, cognitive improvement and anti-inflammatory properties, among other things. Its ability to essentially trick the body into burning fat instead of carbs (a state known as ketosis) can also result in more rapid weight loss than you may have thought possible. This is what Pruvit had to say: Keto-OS is your “ketone operating system”. It was one of the First Therapeutic Ketone Supplements on the market. The proprietary blend is owned by Prüvit and is Dr. Approved, Lab Tested, University backed and the technology in Keto-OS is patent pending, developed by one of the most world renown Dr.’s and experts on Ketosis. Prüvit was the first company approved by University of South Florida to acquire the sub-license rights to use this patent pending technology. It is a powder that you mix with 8=10 oz. of water. Keto-OS is Pruvit’s flagship product and is the first product the company sold when it Continue reading >>

Raspberry Ketones And Weight Loss Review Of Research (updated 2017)

Raspberry Ketones And Weight Loss Review Of Research (updated 2017)

What are raspberry ketones and do they work? Well, if you watch the Dr. Oz Show, you may have heard Dr. Oz call raspberry ketones “The #1 miracle in a bottle to burn your fat.” Since he made that bold statement, I've heard that raspberry ketone supplements are sold so fast that vitamin stores can't keep them on the shelves! So, what I'd like to do is by review the raspberry ketone research — minus the hype that you have already heard about. Only in this way can you make an informed decision about whether raspberry ketone are right for you. Other names for this supplement include red raspberry ketone, and European red raspberry, as well as the more scientific names Rubus idaeus, Rubus strigosus and Framboise Rouge. I'm telling you these other names because if you just searched for “raspberry ketone” you may not find all of the information available. For this review, I'm pretty much going to stick to just calling it raspberry ketone. What Are Raspberry Ketones? Red raspberry ketones are one of many compounds in raspberries and are what gives raspberries their unique smell. Like all things that come from fruits and vegetables, raspberries contain a lot of substances that are healthy —including anthocyanins, vitamin C and beta carotene. As such, raspberry ketones are also antioxidants. Raspberry ketones also “look” similar to synephrine and capsicum — two ingredients that have been used in many weight loss supplements over the years such as the fat burner promoted by Jillian Michaels. This similarity is likely why scientists considered raspberry ketones as a weight loss agent itself. Weight loss supplements that contain raspberry ketones include QuickTrim — the Kim Kardashian supplement —and Apidexin. See my reviews on those products for more informati Continue reading >>

Exogenous Ketones: To Ketone Or Not To Ketone

Exogenous Ketones: To Ketone Or Not To Ketone

My thoughts on Exogenous Ketones After being contacted (following the Youtube Q&A) by several folks – both members of Ketogains and Internet strangers, I felt compelled to write as fair and even-handed a write-up on exogenous ketone supplementation as I feel can be mustered. I condition my response by saying this – I want to deal only in evidence and hypotheses grounded in biochemistry. I admit up front that this will probably become something of a treatise on what constitutes a well-formulated ketogenic diet. I don’t have the time (or the energy) to put together a document that covers all facets of the use of exogenous ketones in sufficient depth, so what I want to do is to address the folks that I see asking me about them most often – those who have excess body fat, and are looking to lose weight. They have been told about the potential benefits to fat loss via exogenous ketones, and they want to know if the hype is real. Those of you who know me (or read my previous post here) know that I like to respond with “it depends.” So…when the question is raised, “Should I supplement with exogenous ketones?” what do you think my answer will be? Probably not! (HA, I tricked you!)…but let’s explore why. As I’m sure this is going to be hotly debated enough (as the topic is raging in numerous ketogenic groups) there isn’t any value in dealing with speculation that doesn’t have a basis in science, nor in anecdotes. The challenge in dealing with exogenous ketone supplementation is two-fold: One side of the debate has a product to sell. Anytime someone’s livelihood is tied to your purchase of their product, bias and subjective interpretation of the evidence should be considered. The evidence (either for or against) their supplemental use by average schl Continue reading >>

My Big, Fat, N=1 Exogenous Ketones Supplementation Experiment (while Eating A Keto Diet)

My Big, Fat, N=1 Exogenous Ketones Supplementation Experiment (while Eating A Keto Diet)

My Big, Fat, n=1 Exogenous Ketones Supplementation Experiment (while Eating a Keto Diet) Here we go. I’ve been slightly apprehensive about sharing this latest experiment with you, because up until recently I was where I’m sure many of you are right now in my belief that exogenous ketones were a mother flippin’ ripoff. After all, all good keto kids know that ketone bodies are the RESULT of putting our bodies successfully in ketosis, so why in the hell would we want to pay to put ketones from outside ourselves into our system? Well, I got my reasons, which I’ll share with you in a bit. First, my purpose: to do an n=1 experiment in order to see if using exogenous ketones can help me lose weight while on a ketogenic diet — that is, a diet that already puts my body in ketosis. ***HUGE DISCLAIMER: I used my own hard-earned money to pay for the exogenous ketones. I was not approached by any company, and I am not doing this experiment on behalf of anybody but myself.*** Now for some background info on me: I’ve been following a keto diet for 20 months now I am approximately 75lbs overweight Aside from an initial fluid loss of 10lb, I have never lost any weight on keto Over these last 20 months I have experimented with altering my macros, intermittent fasting (IF), extended fasting, egg fasting, and meat fasting, and nothing to date has had any measurable, lasting impact on my weight I have PCOS I have low cortisol levels due to chronic Lyme disease that was finally treated in December 2016 and January 2017 I still do consider keto to be a success for me! I used it along with the protocol in the book The Mood Cure to finally get off antidepressants and anti-anxiety medication that I was previously unsuccessful in transitioning off of for 10 years (Note: Don’t ever a Continue reading >>

Does Raspberry Ketone Supplement Work?

Does Raspberry Ketone Supplement Work?

No they wont work! Raspberry Ketone is a molecule found in Raspberries that gave it its aroma. It is used in foods as a flavoring agent. Raspberry Ketone is sold as a fat loss supplement. In rat studies the raspberry ketone had shown positive results, isolated fat cells had shown increased lipolysis. There are no human studies to support these effects of Raspberry Ketone. Stay away from this MAGIC PILL Raspberry ketone is listed in our magic pills section. I have created a supplement checklist that reviews 82 supplements, and arranged on the basis of results. The checklist will help to identify those supplements that works. Continue reading >>

How Long Does It Take For A Herniated Cervical Disc To Heal, So You Can Begin Running Again?

How Long Does It Take For A Herniated Cervical Disc To Heal, So You Can Begin Running Again?

Truth be told, a heniated cervical disc really doesn't heal in the sense that most people think. Once a disc is herniated, that's the way it remains. That being said, the SYMPTOMS from a herniated disc, such as pain, numbeness or tingling, may improve with time. There are several factors which will determine if symptoms will resolve with time: Degree/severity of herniation, morphology of herniation (meaning wether it's centralized or lateral) and if it is impinging upon the Neural elements. More times than not, disc herniations cause an inflammatory reaction around the nerve roots as they exit the spine, which causes the symptoms to wax and wane in thier severity. Most symptoms, improve with time because the inflammatory process dies down, therefore the irritation of the nerve root ceases, and the symptoms improve. On ocasion, the Disc herniation may shrink, or "scar down", which may have the added benefit of decreasing the irritation to the nerve root. SO....again, this is not a straight forward question. If, you do suspect you have a cervical disc herniation, it would be highly recommended to see your PCP to evaluate the severity of the herniation. Continue reading >>

The Beginner’s Guide To Exogenous Ketones

The Beginner’s Guide To Exogenous Ketones

Have you been wondering what exogenous ketones are? If so, you’re not the only one. The keto-dieting world has been buzzing with information about developments on exogenous ketones for awhile now, with many brands producing exogenous ketones that are used by Keto lifestylers around the world. But the majority of Keto dieters don’t completely understand what exogenous ketones are or how they can benefit their diet (or dieting options). In this post, we’ll provide you with easy to read information about exogenous ketones. With this knowledge, you’ll be able to utilize exogenous ketones in your diet, and teach others about their value. Let’s start with the label! The Definition of Exogenous Ketones Two words: exogenous and ketones. The word exogenous describes something that is developed from external factors; something outside of the usual production. So in terms of ketones, this means that exogenous ketones are synthetic: created outside of your body by scientists and then ingested for accelerated ketosis. We assume that you already know what ketones are, but just in case, we’ll give you a brief description of this term as well. Ketones, are organic compounds produced by in your body when your system experiences starvation, or when you restrict carbohydrates and increase fats, which inhibits a starvation-like state that produces ketone bodies. These ketones are an ideal fuel source for your body and your brain. Studies have suggested that when your body is in a ketogenic state, it utilizes oxygen more efficiently in the generation of energy. In short, ketones are secret weapons for anyone looking to take their body’s fueling system to the next level! To restate the point: Exogenous Ketones are ketone supplements. They’re created outside of your body and i Continue reading >>

Cupcakes And Ketones; Do Ketone Supplements Really Work?

Cupcakes And Ketones; Do Ketone Supplements Really Work?

I’ve heard several questions about ketone supplementation for fat loss… they seem to be the next big weight-loss fad. But what are they, and do they really work? Ketones are a natural fuel source produced by your body when glucose (sugar) is not available to use as fuel. This is called nutritional ketosis and it happens when you’re on a very low carb diet, or have fasted for an extended period of time. Once you burn through your glucose stores, your body digs into your stored fat for fuel. Fatty acids are released from your fat cells, and your liver uses those fatty acids to create ketones, which are then burned as fuel. Exogenous (from an external source) ketones have recently hit the market and have been hailed by some as the next great magic fat loss pill. Instead of fasting or cutting carb intake so that your body produces ketones, you’re drinking ketones so you body can then use them as fuel. Sounds great, right? Keep eating carbs and receive the fat burning benefits of NOT eating carbs! If something sounds too good to be true, then it probably is. Remember that to create ketones, your liver uses fatty acids from your fat cells to produce them. If you’re drinking the ketones, then you don’t actually have to dig into your own fat stores to create them. Creating the ketones, not burning them, is what causes your body to use fat. And if you’re now using ketones as fuel, but haven’t even used up your glucose stores first (which is how it happens naturally), then what happens to the glucose? You now have 2 fuel sources, and you can’t burn them both at the same time. Well, studies of ketone supplement use do show that as blood ketones increase, blood sugar (glucose) decreases, but it isn’t because you are burning that glucose; it’s because your insu Continue reading >>

Ketones 101: Exploring The Benefits Of Exogenous Ketone Use

Ketones 101: Exploring The Benefits Of Exogenous Ketone Use

Walk into any supplement store and you’ll see the shelves adorned with what seems like an endless number of products making too-good-to-be-true claims: Lose weight in 24 hours! Lose two inches in two weeks! Between excessive praise and pushy salespeople, it can be difficult to know which supplements are reasonably worth trying—and why. So, when exogenous ketone supplements started showing up on the market, we were honestly a bit skeptical: Are these new supplements worth incorporating into our regimens, and are their apparent benefits backed up by actual scientific research? Today’s post is dedicated to explaining how we came to conclude that yes, exogenous supplements are worth including into your daily routine, and we’re about to tell you why. What are Exogenous Ketones? Simply put, the term “exogenous” refers to things that come from outside the body. Supplements are therefore considered exogenous because you ingest them rather than producing the contents of that supplement inside the body. The opposite of exogenous is “endogenous,” which refers to things that you do produce within your body. To define what “ketones” are, we need to briefly talk about how our metabolism works. Whenever you eat carbohydrates, they’re broken down into glucose (or sugar), which provides your body with the energy it needs to function; however, when you utilize a low-carb diet and don’t have enough glucose, your body adapts by looking for other sources of energy in the body. Eventually, it will turn to your fat cells. Whenever fats are broken down for energy, ketone bodies are produced as a result. Glucose is no longer your body’s primary fuel source, ketones are. (It’s important to note that ketones are always present in the blood, but their levels increase du Continue reading >>

Raspberry Ketone: How Do They Work?

Raspberry Ketone: How Do They Work?

Over the last five years, a compound known as Raspberry Ketone has been closely associated with weight loss. It has been touted as the next weight loss miracle drug, with many manufacturers claiming that the ketones help your body break down fat more efficiently. What are Raspberry Ketones? They are a natural phenolic compound found in red raspberries. This chemical compound gives berries their strong pleasant smell. Until recently, Raspberry Ketones were originally used by the perfume and manufactured food industries, but recently they have been developed to be used in supplements. The structure of Raspberry Ketones has been said to be similar to that of capsaicin, active component in chilli peppers; however, these facts are only backed by studies done on rodents. How Does Raspberry Ketones work? They work in two ways. Firstly they increase the brain chemical called norepinephine, which is a substance released naturally by the nerve cells. The increase of this chemical ultimately breaks down the fat inside of fat cells called adipocytes, which is a cell that controls levels of fat whether it be manufactured or stored. The second way that Raspberry Ketones work is that they increase the secretion of adiponectin, this is a protein, which is created by fat cells, which help to break down fat, regulate sugar levels and regulate metabolism. It has been found that many obese people in fact have low levels of adiponectin. It has been said that the effects of Raspberry Ketone only work when the extract is used, and is in its purest form, and similar grade and dose to what was used in the clinical trials. Health Benefits Weight loss isn’t the only benefit of taking Raspberry Ketones; it has been recommend to aid many health problems such as lowering body cholesterol, fighting Continue reading >>

Raspberry Ketones — Do They Really Help With Weight Loss?

Raspberry Ketones — Do They Really Help With Weight Loss?

Raspberry ketones are chemicals from red raspberries that are thought to help you lose weight fast. Ketones are natural chemicals that give raspberries their enticing aroma, and they also occur in blackberries and cranberries. When ketones are taken from raspberries, they can be used to add fragrance and flavor to foods and products, such as colas, ice cream and cosmetics. The raspberry ketone is actually one of the most expensive products used in the food industry — the natural compound can cost as much as $20,000 per kilogram. That’s why supplement companies use synthetic raspberry ketone, which is much cheaper. Some research in rodents or in test tubes shows that raspberry ketones might increase measures of metabolism and affect a hormone in the body called adiponectin, which regulates metabolism. Raspberry ketones are claimed to cause the fat within cells to be broken down more effectively, which helps the body burn fat faster. The big issue here is that these claims are not supported with human research, as there is no reliable scientific evidence that proves raspberry ketones improve weight loss when taken by people. Are raspberry ketones another common unhealthy way to lose weight? Studies Involving Raspberry Ketones A 2005 study published in Life Sciences evaluated whether or not raspberry ketones help prevent obesity and activate lipid metabolism in rodents. The study involved two groups of mice — one that was fed a high-fat diet and took raspberry ketone doses for 10 weeks and another group that was given a high-fat diet for six weeks first and then began receiving raspberry ketone doses for the remaining five weeks, along with the high-fat diet. The results of the study suggest that raspberry ketones prevent the high-fat-diet-induced elevations in body Continue reading >>

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