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How Do Ketone Supplements Work?

The Ketogenic Diet: Does It Live Up To The Hype? The Pros, The Cons, And The Facts About This Not-so-new Diet Craze.

The Ketogenic Diet: Does It Live Up To The Hype? The Pros, The Cons, And The Facts About This Not-so-new Diet Craze.

If you believe the buzz, ketosis — whether via the almost-zero-carb ketogenic diet or via ketone supplements— can curb appetite, enhance performance, and cure nearly any health problem that ails you. Sound too good to be true? It probably is. Want to listen instead of read? Download the audio recording here… ++++ Wouldn’t it be awesome if butter and bacon were “health foods”? Maybe with a side of guacamole and some shredded cheese on top? “I’m doing this for my health,” you could purr virtuously, as you topped your delectably marbled, medium-rare steak with a fried egg. Well, many advocates of the ketogenic diet argue exactly that: By eating a lot of fat and close to zero carbohydrates you too can enjoy enhanced health, quality of life, performance, brain function, and abs you can grate that cheese on. So, in this article, we’ll explore: What are ketones, and what is ketosis? What, exactly, is a ketogenic diet? What evidence and scientific research supports the ketogenic diet? Do ketone supplements work? Is the ketogenic diet or ketone supplementation right for me? How to read this article If you’re just curious about ketogenic diets: Feel free to skim and learn whatever you like. If you want to change your body and/or health: You don’t need to know every detail. Just get the general idea. Check out our advice at the end. If you’re an athlete interested in performance: Pay special attention to the section on athletic performance. Check out our advice for athletes at the end. If you’re a fitness pro, or interested in geeking out with nutritional science: We’ve given you some “extra credit” material in sidebars throughout. Check out our advice for fitness pros at the end. It all started with the brain. If you’ve called Client Care at Pr Continue reading >>

How To Use (and Not To Use) Exogenous Ketones For Weight Loss

How To Use (and Not To Use) Exogenous Ketones For Weight Loss

“How do I use ketones to help me lose weight?” Great question. It’s worth the few minutes to understand how exogenous ketones can help people lose weight on a ketogenic diet, and not just jump to the conclusion that ketones = weight loss. Breaking Down Ketone Weight Loss Misconceptions The most common misconception (perhaps due to excessive marketing claims) is that taking ketone supplements will induce immediate weight loss. The purpose of this article is to explain how to use ketones as a piece of the puzzle in your weight loss lifestyle. Remember exogenous ketones are supplements. Very effective at what they do, but none the less, should be supplementary to a low carb/ketogenic style of eating that is geared towards weight loss (if weight loss is the goal). Ketones don’t cause weight loss, they help cause ketosis. Ketosis is a metabolic state where your body is using fatty acids for its primary source of energy. Just because you are using fat does not necessarily mean you are going to be losing weight or have a decrease in body fat percentage over an extended period of time. I have been in deep nutritional ketosis (>3.0mmol/dL) and had an increase in body fat percentage. I’ve also been in deep nutritional ketosis and had a decrease in body fat percentage. It all depends on how much fat and protein you are eating, in addition to being below a carb threshold that will induce ketosis. Please don’t take this to mean starve yourself. It just means that the average male American has over 40,000 calories in stored body fat and can, therefore, afford to eat a lower calorie ketogenic diet, and still survive (and thrive!). Take home message: Exogenous ketones are a tool to get you into ketosis or to boost your energy levels while already in ketosis. If your motive Continue reading >>

Ask The Supplement Expert: Will Ketones Help Me Burn Fat?

Ask The Supplement Expert: Will Ketones Help Me Burn Fat?

Q: Will taking ketone supplements, while eating a normal diet, provide the same fat-loss benefits as being on a seriously carb-restricted, or ketogenic diet? The very short answer to your question is "probably not," but given how complex the burgeoning field of study into nutritional ketosis is, that simple answer requires a bit of unpacking. The basic thinking when it comes to supplementing with ketones and their effect on fat loss is this: When your body is consistently carb-depleted, it produces ketones as a mechanism to utilize fat (and to a lesser extent, amino acids from muscle) as fuel. These ketones can also be used as an alternative to glucose as fuel to support your brain, muscles, heart, and other organs. Once you have a high enough presence of ketones in the blood, usually around 0.5 to 3.0 mM per deciliter of blood (as can be measured with urinalysis ketone strips), you have entered what is known as "nutritional ketosis." To be clear, your body is what is producing those ketones, though. Ketone supplement advocates extend that line of thinking beyond the ketones your body is manufacturing on its own. Their case is that if consuming a ketone supplement raises your blood ketone level to the point where you are technically in ketosis, then you must be burning fat with the same effectiveness if you came by your ketosis the old-fashioned way. Unfortunately, the scant scientific evidence that currently exists doesn't support connecting the dots this way. Researchers out of the University of Sao Paulo, in Brazil, recently gave a group of rats substantial doses of beta hydroxybutyrate (exogenous ketones) both acutely and for four weeks.[1] Not surprisingly, the researchers concluded that consuming oral ketones increased circulating ketones (ketonemia). To which I s Continue reading >>

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Great article. You actually answered my question as to the ratio of the 3 BHB salts which is quite helpful for me. For me, I had Keto O/S and found it quite good – my favorite was the chocolate swirl. But it was and is very expensive. Only 15-20 servings and would break the bank. So I turned to KetoCaNa and I’ve tried two flavours. Both of them were so salty that I almost threw up every time. Like flavoured sea water. Also only 15 serving per bottle. Then I turned to Ketond which is okay – Tigers Blood and Caramel Macchiato. What I like about Ketond is that it has a full 30 servings and is very transparent with it’s ingredients. It’s also the same price as Keto OS but you get 30 servings. But still, not the best taste. So in the end, I ordered 1kg of pure BHB Magnesium from a supplier in China and I will be developing my own Ketone product with 30 servings as a lower price than all the competitors, and with more Magnesium, and Calcium in it than Sodium so that it tastes the best and actually helps with weight loss (which Magnesium is proven to do at the right amount). What the companies don’t tell you is that actually Sodium BHB is the cheapest, then Calcium BHB and then Magnesium BHB to source so I would be interested in knowing if what you wrote is actually true or just an excuse to make the product cheaper. Probably a mix of both. So I have 2 questions Ben: 1. If you had to split the 11.7g of BHB into Sodium, Ca, and Mg, what ratio would you do for the best health results and potential weight loss? The current products on the market are about an 80/12/8 split. I would think it should be the other way around. 2. When I develop my own product and sell it, would you be up for sampling it and reviewing it on your website here? What flavours do you like/would Continue reading >>

Prüvit Ketones Review

Prüvit Ketones Review

Prüvit [1]—or to be more precise, health expert Ben Greenfield—believes carbs are killing us. [2] “We’re operating in a high carb world where food is abundant and it is destroying our brains and bodies,” Greenfield says in his lengthy but chock-a-block blog of information about a better body through ketosis—and, ultimately, his supplements. Supplements that claim will not only help you shed pounds, but build a better body by rewiring your metabolism—or “biohacking”—to give you more energy, strength, and focus while you lose weight and sleep better. Not to mention you’ll be in an amazing mood. It’s a lot of claim. Prüvit supplements are supposed to add ketones to your blood—if you’ve ever been on a low-to-virtually-no carb diet, you’ve heard of ketosis [3]—which triggers weight loss. Greenfield calls it a kind of “body-hacking.” What Prüvit Is and How Does It Work? Prüvit, a play on the words prove and it, cites research that includes articles, studies, and clinical trials, but quickly adds that it’s not responsible for inaccuracies in the data. Not the first in the ketosis or ketone-diet zone by a long shot, nonetheless Prüvit says it’s tackled the “supplement world by creating the world’s first consumer-based ketone supplement drink, KETO//OS®.” [4] Described as a beverage blend of “advanced macro nutritionals (that) promotes optimized cellular regeneration, energy and longevity,” it comes in flavors like Maui-Punch, Chocolate Swirl and Orange Dream that range from $75 to $130 for 20 servings. Another product, KETO/KREME, “derived from the heart of the coconut, is one of the healthiest natural fats known to the world. Our bodies convert fat into energy quickly giving you a powerful mental boost—we call it brai Continue reading >>

Effects Of Exogenous Ketone Supplementation On Blood Ketone, Glucose, Triglyceride, And Lipoprotein Levels In Sprague–dawley Rats

Effects Of Exogenous Ketone Supplementation On Blood Ketone, Glucose, Triglyceride, And Lipoprotein Levels In Sprague–dawley Rats

Go to: Background Emerging evidence supports the therapeutic potential of the ketogenic diet (KD) for a variety of disease states, leading investigators to research methods of harnessing the benefits of nutritional ketosis without the dietary restrictions. The KD has been used as an effective non-pharmacological therapy for pediatric intractable seizures since the 1920s [1–3]. In addition to epilepsy, the ketogenic diet has elicited significant therapeutic effects for weight loss and type-2 diabetes (T2D) [4]. Several studies have shown significant weight loss on a high fat, low carbohydrate diet without significant elevations of serum cholesterol [5–12]. Another study demonstrated the safety and benefits of long-term application of the KD in T2D patients. Patients exhibited significant weight loss, reduction of blood glucose, and improvement of lipid markers after eating a well-formulated KD for 56 weeks [13]. Recently, researchers have begun to investigate the use of the KD as a treatment for acne, polycystic ovary syndrome (PCOS), cancer, amyotrophic lateral sclerosis (ALS), traumatic brain injury (TBI) and Alzheimer’s disease (AD) with promising preliminary results [14–26]. The classical KD consists of a 4:1 ratio of fat to protein and carbohydrate, with 80–90 % of total calories derived from fat [27]. The macronutrient ratio of the KD induces a metabolic shift towards fatty acid oxidation and hepatic ketogenesis, elevating the ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) in the blood. Acetone, generated by decarboxylation of AcAc, has been shown to have anticonvulsant properties [28–32]. Ketone bodies are naturally elevated to serve as alternative metabolic substrates for extra-hepatic tissues during the prolonged reduction of glucose Continue reading >>

Raspberry Ketone

Raspberry Ketone

RASPBERRY KETONE Overview Information Raspberry ketone is a chemical from red raspberries, as well as kiwifruit, peaches, grapes, apples, other berries, vegetables such as rhubarb, and the bark of yew, maple, and pine trees. People take raspberry ketone by mouth for weight loss. It became popular for weight loss after it was mentioned on the Dr. Oz television show during the segment called "Raspberry ketone: Miracle fat-burner in a bottle" in February 2012. People apply raspberry ketone to the skin for hair loss. Raspberry ketone is also used in foods, cosmetics, and other manufacturing as a fragrance or flavoring agent. How does it work? Raspberry ketone is a chemical from red raspberries that is thought to help for weight loss. Some research in animals or in test tubes shows that raspberry ketone might increase some measures of metabolism. It might also affect a hormone in the body called adiponectin. Adiponectin can increase the rate at which the body burns fat and reduce appetite. However, it is important to keep in mind that there is no reliable scientific evidence that raspberry ketone improves weight loss when taken by people. Continue reading >>

Exogenous Ketones Pros And Cons

Exogenous Ketones Pros And Cons

What Are Exogenous Ketones? Exogenous Ketones (EK for short) are ketone supplements and by definition, a supplement is a thing added to something else in order to complete or enhance it. Think about it like building muscle, good supplements can enhance your results, but if you don’t eat right and exercise, supplements are just useless. You can’t just sit on the couch to watch TV, eat potato chips all day and drink some supplements and expect to gain muscle. A supplement is not a miracle. It’s just an addition and before you add it to your diet, you need to get the basic right first, which is dieting and exercise in the case of building muscles. The supplements are not going to lift the heavy weights for you. You do! Back to the case of EK. If you cheat on your keto diet and eat a ton of carbs, and you want to use EK as a way to feel better and less guilty about it, it’s probably not a smart choice because EK won’t do anything for you (more on this later). However, if you are eating LCHF and somehow you’re not feeling your best, EK can be helpful and we will explain more below. Our Approach We own and manage a few growing Keto Facebook groups with tens of thousands of members and we often see the exogenous ketones topic comes up. We have seen a lot of confusion and criticism as well as support from our members. Most of the complaints are normally because of the expensive price of some products, the lack of understanding about what the product is and what it does to your body or because some sellers/promoters try to bend the truth to get you buy their products or recruit you into their multi level marketing team. We recently ran a survey in our private group and asked people if they have used EK before and if it worked for them. Here’s the result: Many peopl Continue reading >>

Why I’m Using Exogenous Ketone Supplements

Why I’m Using Exogenous Ketone Supplements

Exogenous ketone supplements have gotten extremely popular lately with high performers like Tim Ferriss posting non-stop about all the benefits they offer, so I decided to give it a try as a self-experiment. Man I am glad I did. I was a bit skeptical at first because of all the hype, but I really felt the difference it made for me. As with most guys in my generation, I’ve take tons of different supplements trying to find the perfect shortcut, putting all kinds of weird stuff into my body. Then I realized how ridiculous that was and stopped taking most supplements. Needless to say I was a little hesitant to try this stuff because I have pretty much only been taking protein, greens, and pre-workout sometimes (pretty basic and well-established supplements). But with a bunch of my friends and people I follow talking about the benefits of a ketogenic diet (or ketosis) I thought it would be worth giving it a shot. The reason I wasn’t turned off by exogenous ketones (and the reason for taking it actually makes sense to me) is that ketosis is a completely natural metabolic state your body goes into in the absence of carbohydrates. Instead of burning sugar for primary energy, your body starts burning the breakdown of fat (or ketones) as your primary energy source. The reason I really wanted to try them is that ketones are a far preferred energy source to your brain than glucose or carbs, but getting into ketosis can be miserable and I want to continue to eat carbs for the working out I do. Exogenous ketones are basically supplemental ketones. When you take them, your body immediately starts using ketones for energy just like you would if you were in a deep state of ketosis. This means no crash diets, no low carb craziness; I can just have the benefits of ketosis whenever I w Continue reading >>

Do Ketones Matter?

Do Ketones Matter?

A low-carb diet is, indisputably, one of the most effective ways to lose excess body fat. Over and over again, studies have proven the myriad benefits of carbohydrate restriction. Being fat-adapted brings several advantages, as you will have access to your greatest energy store - body fat. Do More Ketones Enhance Fat Loss? Contrary to what you may have thought, high levels of ketones will not guarantee enhanced fat loss. When you are in ketosis, the level of ketones in your bloodstream won't tell you how much fat you are burning. It will only tell you how much energy you currently have in your "fuel tank". Your body continuously produces and consumes ketones and over time, it will adapt and optimise the level of ketones in your body. Let's look at the evidence. This review of studies found a correlation between fat loss and the level of acetone, one of the ketone bodies that can be measured with a breath ketone meter. However, studies that are listed in the review compare the effects of a standard low-fat, high-carb diet to a high-fat, low-carb diet. As we know from several studies, low-carb diets over-perform high-carb diets. However, if we want to see how ketone levels affect fat loss, it would be necessary to compare low-carb diets and effects of different levels of carbohydrate restriction. High ketone levels over 3 mM (also known as starvation ketosis) may, in fact, slow down fat loss. High ketone levels will likely elevate your insulin levels and as a result block the release of free fatty acids from your cells. Ketosis is Not Just a Tool for Weight Loss It's simple: if you want to lose body fat, you need to stay in calorie deficit and use your body fat for energy. A low-carb diet is a great tool that will help you achieve that. With stabilised glucose levels and Continue reading >>

Can Ketone Pills And Powders Really Provide The Same Benefits As A Low-carb Diet?

Can Ketone Pills And Powders Really Provide The Same Benefits As A Low-carb Diet?

The ketogenic diet is is enjoying a surge of popularity these days and for good reason. Going “keto” can help you tap into your body’s stored fat—up to 100,000 calories of readily available energy—allowing you to push longer and harder during training without constantly refueling. Of course, this comes at a price: You have to eradicate nearly all carbohydrates from your diet and subsist on fats—they should make up 70 to 80 percent of what you eat—and protein. Making the metabolic shift to full fat-burning mode can take three to six weeks. That’s a tall order. So the performance nutrition market has responded with a short- cut: ketogenic supplements. They come in powders, capsules, chews, meal replacements, and even coffee creamer and claim to help you immediately burn more fat, shed pounds, and perform better—without giving up bread. Those are some incredible benefits. But look past the promises and the science unravels. Keto supplements claim they can trick your metabolism into thinking it’s carb deprived and send it into ketosis. This could be an evolutionary adaptation the human body created to survive famine. Lisa Sasson, a nutritionist at New York University, explains that during ketosis, the liver begins to break down fatty acids, sending ketone compounds into the bloodstream, which can be used to fuel muscles. Hypothetically, taking supplements with synthetic ketones would move the body into ketosis in minutes and last a couple of hours, says Brendan Egan, an associate professor of sports and exercise physiology at Dublin City University. But that doesn’t mean you’ll suddenly be able to power through burpees or run for miles without stopping. Of the few reports done on commercially available ketone supplements, some suggest only a negligib Continue reading >>

Are Exogenous Ketones Right For You?

Are Exogenous Ketones Right For You?

I’ve spent a lot of time lately analysing three thousand ketone vs. glucose data points trying to determine the optimal ketone and blood sugar levels for weight loss, diabetes management, athletic performance and longevity. In this article, I share my insights and learnings on the benefits, side effects and risks of endogenous and endogenous ketosis. But first, I think it’s important to understand the difference between exogenous and endogenous ketosis: Endogenous ketosis occurs when we go without food for a significant period. Our insulin levels drop, and we transition to burning body fat and ketones in our blood rise. Exogenous ketosis occurs when we drink exogenous ketones or consume a ketogenic diet. Ketones are important. As blood glucose decreases, the ketones in your blood increase to keep our energy levels stable. The chart below shows three thousand blood glucose vs ketone values measured at the same time from a range of people following a low carbohydrate or ketogenic diet. While there is generally a linear relationship between glucose and ketones, each person has a unique relationship between their blood glucose and ketone values that provide a unique insight into a particular person’s metabolic health. Hyperinsulinemia has been called as the “unifying theory of chronic disease” [1] [2] [3] [4] [5]. It’s beneficial to understand where you stand on the spectrum of metabolic health and insulin sensitivity. The chart below shows the typical relationship between blood glucose and blood ketone for a range of different degrees of insulin resistance/sensitivity. If your blood glucose levels are consistently high it’s likely you are not metabolising carbohydrate well. When you go without food, endogenous ketones are slow to kick in because your insulin Continue reading >>

Ketone Ester Review: What Are They, And Do They Work?

Ketone Ester Review: What Are They, And Do They Work?

It's an exciting day at the KetoConnect household! We finally got our hands on the first commercially available ketone ester! The only company currently making this stuff is KetoneAid and they were nice enough to send us a sample to try for ourselves. We have tried most of the exogenous ketone supplements on the market and have not been impressed, but this is something completely different. Exogenous Ketones - Salts VS Esters The difference is night and day. When supplementing with the current BHB Salts on the market the impact is negligible. Often I will feel absolutely nothing, where other times I will notice a small benefit in energy and focus. It turns out this is due to the small dose that all BHB Salts deliver. There is an upper limit to how much you can consume at a given time because the ketones are binded to a salt such as sodium, potassium or magnesium. Ketone Esters on the other hand have no limit. You can consume exponentially more at a given time, which leads to a dramatic increase in benefits. The difference is rather astonishing and has completely reversed my thoughts on supplementing ketones and the future of the ketone supplement market. The Taste - Yes...It's That Bad! While the taste is much improved from the original iteration of these ketone esters, it's still pretty terrible. I'd describe it as a mix between rubbing alcohol and what I imagine toilet cleaner would taste like, with a squeeze of lemon. I'm sure this will continue to improve over time, and while it is terrible I don't feel it makes the supplement too prohibitive. It's easy to justify a few minutes of discomfort for hours of increased productivity. We Monitored Our Ketone and Glucose Levels After choking down our respective drinks, we started monitoring our blood ketone and glucose leve Continue reading >>

Do Raspberry Ketones Really Work? A Detailed Review

Do Raspberry Ketones Really Work? A Detailed Review

If you need to lose weight, you are not alone. More than a third of Americans are overweight, and another third are obese (1). Only 30% of people are now at a healthy weight... being overweight has become the new "normal." The problem is, conventional weight loss methods are so difficult that 85% of people fail in the long run (2). However... there are many products out there that are claimed to make things easier. These are herbs, shakes and pills that are supposed to help you burn fat or reduce your appetite. Among the most popular ones is a supplement called Raspberry ketones. Raspberry ketones are claimed to cause the fat within cells to be broken down more effectively, helping the body burn fat faster. They are also claimed to increase levels of adiponectin, a hormone that helps to regulate metabolism. This article reviews the current scientific research behind raspberry ketone supplements and whether they are actually worth considering. Raspberry ketone is a natural substance that gives red raspberries their powerful aroma. This substance is also found in small amounts in blackberries, cranberries and kiwis. It has a long history of use in cosmetics and has been added to soft drinks, ice cream and other processed foods as a flavorant. Actually... most people are already eating small amounts of raspberry ketones, either from the fruits themselves or because of their popularity as a flavorant (3). Only recently did they became popular as a weight loss supplement. Even though the word "raspberry" may appeal to people, the supplement is actually NOT derived from raspberries. Extracting raspberry ketones from raspberries is insanely expensive, because you need 90 pounds (41 kg) of raspberries to get the amount needed for a single dose! In fact, a kilogram (2.2 pounds) Continue reading >>

Cupcakes And Ketones; Do Ketone Supplements Really Work?

Cupcakes And Ketones; Do Ketone Supplements Really Work?

I’ve heard several questions about ketone supplementation for fat loss… they seem to be the next big weight-loss fad. But what are they, and do they really work? Ketones are a natural fuel source produced by your body when glucose (sugar) is not available to use as fuel. This is called nutritional ketosis and it happens when you’re on a very low carb diet, or have fasted for an extended period of time. Once you burn through your glucose stores, your body digs into your stored fat for fuel. Fatty acids are released from your fat cells, and your liver uses those fatty acids to create ketones, which are then burned as fuel. Exogenous (from an external source) ketones have recently hit the market and have been hailed by some as the next great magic fat loss pill. Instead of fasting or cutting carb intake so that your body produces ketones, you’re drinking ketones so you body can then use them as fuel. Sounds great, right? Keep eating carbs and receive the fat burning benefits of NOT eating carbs! If something sounds too good to be true, then it probably is. Remember that to create ketones, your liver uses fatty acids from your fat cells to produce them. If you’re drinking the ketones, then you don’t actually have to dig into your own fat stores to create them. Creating the ketones, not burning them, is what causes your body to use fat. And if you’re now using ketones as fuel, but haven’t even used up your glucose stores first (which is how it happens naturally), then what happens to the glucose? You now have 2 fuel sources, and you can’t burn them both at the same time. Well, studies of ketone supplement use do show that as blood ketones increase, blood sugar (glucose) decreases, but it isn’t because you are burning that glucose; it’s because your insu Continue reading >>

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