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How Are Ketones Measured

Blood Ketones

Blood Ketones

On This Site Tests: Urine Ketones (see Urinalysis - The Chemical Exam); Blood Gases; Glucose Tests Elsewhere On The Web Ask a Laboratory Scientist Your questions will be answered by a laboratory scientist as part of a voluntary service provided by one of our partners, the American Society for Clinical Laboratory Science (ASCLS). Click on the Contact a Scientist button below to be re-directed to the ASCLS site to complete a request form. If your question relates to this web site and not to a specific lab test, please submit it via our Contact Us page instead. Thank you. Continue reading >>

Ketone Testing

Ketone Testing

Tweet Ketone testing is a key part of type 1 diabetes management as it helps to prevent a dangerous short term complication, ketoacidosis, from occurring. If you have type 1 diabetes, it is recommended that you have ketone testing supplies on your prescription. Ketone testing may also be useful in people with other types of diabetes that are dependent upon insulin. Why test for ketones? Ketones are produced by the body as an alternative source of energy to sugar. The body produces ketones by breaking down fats, this process is known as ketosis. Ketones may be produced as part of weight loss, however, it’s important for people with diabetes on insulin to note that ketones can be produced when the body has insufficient insulin. When the body has too little insulin, it means that cells of the body cannot take in enough sugar from the blood. To compensate for this, the body will start to break down fat to provide ketones. However, if a high level of ketones is produced, this can cause the blood to become acidic which can lead to illness and even potential danger to organs if not treated in time. This state is referred to as diabetic ketoacidosis. Where can I get ketone testing kits and sensors? The most accurate way of testing for ketones is to use a meter that measures blood ketone levels. The following blood glucose meters are able to test blood ketone levels in addition to blood glucose levels: Abbott - FreeStyle Optium Neo Menarini - GlucoMen LX Plus If you take insulin, you should be able to get these prescribed by your GP. You can also test urine for ketone levels, however, urine ketone testing is not as accurate as blood ketone testing as the levels of ketones in the urine will usually only reflect a level of up to a few hours previously. When to test for ketones? Continue reading >>

Why I Stopped Testing My Ketones On A Ketogenic Diet

Why I Stopped Testing My Ketones On A Ketogenic Diet

On measuring Ketones. Like many people, when I first started a Ketogenic diet in early 2014 I bought the Ketostix and just couldn’t wait to see the color change. And change it did! It was neat, and it provided motivation for me to continue. Eventually, I got a blood meter, a breath meter and spent lots of time (and money) testing ketones. Between a Ketonix Breath Ketone Analyzer, as well as dozens of blood ketone test strips, I’ve probably spent well over $500 testing ketones. The main thing I learned from my extensive ketone testing regimen is that the results vary widely and there’s little application to my goals. Eventually, I stopped testing and here are several reasons why: 1. Burning fatty acids from fat is the main benefit of a ketogenic diet On a ketogenic diet, some of the brain’s energetic demand is fueled by ketones, but the heart, muscles, etc. are fueled by fatty acids. Most of the energy we utilize both at rest and at sub-maximal exertion on a ketogenic diet is fatty acid, not ketones. Quoting Dr. Ron Rosedale on chasing ketones at the Keto Summit: “I don’t want people to have the mindset that it’s the ketones that are the benefit of the diet. They are a beneficial side effect, but the main benefit is that you are burning fatty acids from fat. The more fatty acids from fat you are burning, the less glucose you need to burn. And that’s really where you are getting the benefit…So ketones are great but the term ketogenic diet indicating that the diet is so good because you are generating all these ketones is a misinterpretation of the benefit. The main benefit is that you are burning fatty acids, and as a side effect of burning fatty acids you are producing ketones that your body can burn too!” 2. Urine Ketones aka “peetones” are ridic Continue reading >>

Advantages Using Ketonix

Advantages Using Ketonix

KETONIX is an excellent alternative to monitor and record your levels of ketosis compared to urine and blood tests. KETONIX Ketone Breath Monitor is a one-time cost and is simple to use while being extremely portable and robust. It has never been easier to see and monitor metabolic ketone production So what are the advantages of using KETONIX instead of urine strips and/or blood ketone meters? KETONIX vs. Urine Strips Urine strips indicate the excess concentration of Acetoacetate in the urine. KETONIX indicates the acetone in your breath. Acetone is produced from the breakdown of acetoacetate in blood. Measurement units are not the same as the concentration of acetoacetate in blood is higher due to less volume (higher density) and is typically measured in mmol/l. The concentration of acetone in breath is lower due to much more volume (lower density) and is measured in PPM. Again, urine strips measures acetoacetate in urine, blood meters measures beta-hydroxybutyrate in blood and KETONIX measures acetone in breath (air). Urine strips can only be used once. KETONIX is reusable and can be used over and over again. Urine strips show a historical value of the excess production. KETONIX shows a real-time value of what is in the blood via exhaled ketones! Urine strips tests need urine and somewhere private to do the test. You can perform tests using KETONIX wherever you can access a powered USB port or the optional KETONIX battery pack. KETONIX may be stored in the bag that was included with the product. Urine strips cost per test. KETONIX is a one-time investment! KETONIX vs. Blood Ketone Meter Blood ketone meters measures Beta-Hydroxybutyrate in blood, not Acetoacetate or acetone. Blood ketone measure requires test strips which are expensive and often require a prescription. Continue reading >>

A New Toy Measuring Blood Ketones

A New Toy Measuring Blood Ketones

I just got a new toy: a device for measuring blood ketones. This is a far more exact and reliable measurement than testing for urine ketones using cheap dipsticks. Ketosis is of course the state the body is in when eating very low carb. Ketones, made from fat, will then fuel the brain instead of glucose. So who needs one of these gadgets? Perhaps nobody. Obviously it’s easy to eat LCHF without it. This is for curious nerds (like me) and for those who want definite proof that they are eating so little carbs that insulin levels are low and fat burning is maximized. A ketone level somewhere between 1.5 – 3 is said to be an optimal level for maximizing weight loss. It means that insulin levels are very low. As you can see my first measurement was 0.2, after a caesar sallad dinner. I’m not surprised as I’ve probably eaten at least 50 grams of carbs a day lately. I will try it out fasting in the mornings during the coming days. Perhaps I’ll try being really strict with the carbs for a while to see what happens. Have you tried one of these or are you interested in doing it? Continue reading >>

Blood Beta-hydroxybutyrate Correlates Better With Seizure Reduction Due To Ketogenic Diet Than Do Ketones In The Urine

Blood Beta-hydroxybutyrate Correlates Better With Seizure Reduction Due To Ketogenic Diet Than Do Ketones In The Urine

Abstract To investigate whether it is better to use blood beta-hydroxybutyrate (BHB) or urinary ketones to monitor ketogenic diet (KD). In 33 patients on KD we measured ketosis in two different ways. At the 3-monthly visits to the clinic we measured BHB in capillary blood obtained by finger-prick and the level of ketones in the urine using a urine dipstick. If the patient was able to collect urine, the urinary ketones were also measured every day at home. We compared the degree of ketosis with seizure reduction. BHB measured during the 3-monthly visits correlated with seizure reduction at 3 and 6 months (p = 0.037 and 0.019, respectively). Urinary ketones measured at the same time did not correlate at any visit. The averaged values of the daily measured ketones in the urine did not correlate either. BHB correlates better with seizure reduction than do ketones in urine. It is, therefore, better to use BHB to monitor KD even if BHB is measured less frequently than urinary ketones. Fig. 2. BHB concentration related to reduction at 3 months. Fig. 3. BHB concentration related to reduction at 6 months. Fig. 4. Ketones in urine (average) related to reduction at 3 months. Spearman rank: R = 0.10, p = 0.32. Fig. 5. Ketones in urine (average) related to reduction at 6 months. Spearman rank: R = 0.09, p = 0.36. Continue reading >>

Measuring Ketosis: What Are Keto Sticks And Keto Strips?

Measuring Ketosis: What Are Keto Sticks And Keto Strips?

Ketosis is a metabolic state where the liver breaks down fat to produce ketones. Ketones, on a ketogenic diet, are the primary fuel source for the body. If you’re new to the ketogenic diet and you still have questions, consider reading our Comprehensive Beginner’s Guide to Keto > There are three main ways to measure the ketones in your body, all of which have their advantages and disadvantages. The most common ways to measure are: Blood Ketone Meter. Very accurate but the strips are extremely expensive. Breath Ketone Meters. More accurate than the urine strips, but can sometimes vary in accuracy. Cheaper than blood strips in the long-run. Urine Stricks. This will answer the question “Am I in ketosis?” but will not provide an accurate measure of blood ketones. Scroll down to read a more in-depth analysis of each, and what we recommend for you. Measuring Ketones with Urine Sticks Urine sticks will always be the cheapest and easiest way to measure ketosis. For beginners, this should cover everything you need – there is no point in getting more complex blood strips so early on when you are still trying to understand the nuances of a ketogenic diet. Ultimately, keto sticks are very easy to use – you hold the sticks in your urine stream for a few seconds, and within 10-15 seconds you should notice a color change in the strip (if you are in ketosis). The color of the stick typically is measured in red: light pink being low in ketone production and dark purple being high in ketone production. While keto sticks can be ideal for a general answer to the question “Am I in ketosis?”, they aren’t precise with their accuracy. They measure the acetoacetate in your urine, which is an unused ketone by the body. As you get deeper into ketosis and your body adapts, your b Continue reading >>

Why Ketone Measurements Are Important

Why Ketone Measurements Are Important

Nova Max Plus incorporates advanced technology for accurate and precise self-monitoring of blood glucose and ketones by people with diabetes. Nova Max Plus has the most comprehensive features for fast, easy, and error-free blood glucose and ketone monitoring. Glucose and Ketones on the Same Meter The Nova Max Plus Glucose Meter automatically converts itself to a Ketone meter by inserting the Nova Max Plus Ketone strip. Why Ketone Measurements Are Important Diabetic Ketoacidosis (DKA) is a life-threatening metabolic complication of diabetes with a mortality rate of 2%-10%1 DKA is the leading cause of hospitalization, morbidity, and death in children with type 1 diabetes 2 The use of a blood test for early detection of increased blood ketone levels can help to avert DKA3,4,5 According to the ADA, blood ketone testing should be performed on sick days and whenever glucose is greater than 250-300 mg/dL. Laffel L. Endocrinol Metab Clin North Am 2000;29:707-723. Casteels K et al. Rev Endoc Metab Disord 2003;4(2):159-166. Laffel LM et al. Diabet Med 2005;23(3):278-284. Umpierrex GE et al. Treat Endocrinol 2003;2(2):95-108. Guerci B et al. Diabetes Metab 2005;31:401-406. ADA. Diabetes Care 2004;27:S91-103. No Coding Needed Miscoded meters can lead to glucose errors as large as 50%.1 2 Boyd, J. et al. (2003). Quality specifications for glucose meters: Assessment by simulation modeling of errors in insulin dose. Clinical Chemistry, 47(2), 209-214. Raine, C. (2007). Significant insulin dose errors may occur if blood glucose results are obtained from miscoded meters. Journal of Diabetes Science & Technology, 1(2). No Maltose Error Nova Max Plus prevents falsely elevated glucose results due to non glucose sugars in the blood such as maltose. Test strips that use the glucose dehydroge Continue reading >>

Ketones Urine Test

Ketones Urine Test

Urine ketones are usually measured as a "spot test." This is available in a test kit that you can buy at a drug store. The kit contains dipsticks coated with chemicals that react with ketone bodies. A dipstick is dipped in the urine sample. A color change indicates the presence of ketones. This article describes the ketone urine test that involves sending collected urine to a lab. A clean-catch urine sample is needed. The clean-catch method is used to prevent germs from the penis or vagina from getting into a urine sample. To collect your urine, the health care provider may give you a special clean-catch kit that contains a cleansing solution and sterile wipes. Follow instructions exactly so that the results are accurate. Continue reading >>

How To Test Your Blood With A Home Ketone Meter

How To Test Your Blood With A Home Ketone Meter

testing is used by people with diabetes and by people on a ketogenic diet. You can test your urine or your blood for ketones. But because urine testing is not as accurate, the American Diabetes Association recommends blood ketone testing with a ketone meter as the preferable method. If you have diabetes, you should discuss home blood ketone testing with your doctor to learn whether it is recommended in your case and when you should perform the testing. Ketone testing is particularly important during periods of illness. Blood Ketone Meters for Testing at Home You will need a blood ketone meter and a kit that include the lancet pen and ketone test strips. These meters also will read blood glucose test strips, and both will download their results to your computer. Other brands and models may be available, including: Precision Xtra: This meter from Abbott Diabetes Care can store up to 450 measurements and will display your blood glucose averages over different time periods. You need to enter a code to switch from glucose testing to ketone testing. Users seem happier with the Precision brand, and researchers find it to be the more accurate. The strips require 1.5 microliters of blood. It also features a backlit display. Nova Max Plus: This meter from Nova Biomedical is often provided free with the purchase of two boxes of test strips. You don't have to enter a code to switch it from blood glucose to ketone testing; it does that automatically when you insert a ketone test strip. If you are using it primarily for blood glucose, it will remind you to test for ketones if your blood sugar level is 250 mg/dL or higher. The test strips for the Nova Max are less expensive but also flimsier and give more error messages, requiring retesting. The strips require less blood than the Prec Continue reading >>

3 Best Ways To Measure Ketones For Your Ketogenic Diet (review & Buyers Guide)

3 Best Ways To Measure Ketones For Your Ketogenic Diet (review & Buyers Guide)

How do you get accurate readings of ketones? Which methods actually work? These are common questions I going to help you with in this article. Anyone interested in using the latest nutritional research to improve their health has likely heard of a ketogenic diet. Ketogenic diets are a simple way to get your metabolism to prioritize the consumption of fatty acids, also known as ketones, when at rest or exercising. While there is a wide body of research that confirms the benefits of this type of nutritional plan, for the average user at home – one big question remains. How can you measure ketone levels to ensure your body is reaching a perfect state of ketosis? Without an accurate method of ketosis measurement, you will never achieve an optimized LCHF or ketogenic diet. However, it has not always been easy to measure your level of ketosis at home. At least this concern is now a thing of the past, because there are many ways to measure ketone levels easily and accurately in the comfort of your own home. Find out the very best method to test your level of nutritional ketosis that strikes the perfect balance of ease, price and quality. Before getting too deep into the different methods for measuring ketosis, it is important to first look at exactly why measuring them is so important and to clarify some of the more complex scientific terms. Ketone Testing Terminology If you have decided to try a ketogenic diet to achieve nutritional ketosis, then finding an accurate way to measure your ketone levels is important. You need to be able to maintain yourself in the optimal zone where fat is used as energy rather than glucose. Too little ketone and you will not see any positive effects. But higher levels give no real benefit and could indicate a serious problem with your diet. Li Continue reading >>

Tracking Blood Ketones: Behind The Scenes Data On The Ketogenic Diet

Tracking Blood Ketones: Behind The Scenes Data On The Ketogenic Diet

Tracking Blood Ketones: Behind the Scenes Data on the Ketogenic Diet I’ve tried a lot of diets. I first went vegetarian, then slow carb, then gluten-free, then Paleo. I even did a 28-day Chipotle diet, which is exactly as awesome as it sounds. Eventually I found the Ketogenic diet. For me, like for many people in our communities, this all started with a health concern. I was born with a heart condition. It never impacted my life, but it was there, lingering. When I was a junior in college, a few classmates and I were out enjoying late night pizza. Out of nowhere, one classmate suddenly jolted upright and fell off his stool. He died. I found out the next morning it was from a lingering heart condition, not too unlike my own. I started to think about my health a lot more after that. I read about nutrition and started exploring the confusing world of diets. As I learned more and as I became more involved in Quantified Self, I found myself wanting to quantify these diets. That’s what drew me to Keto. It’s the most measurable diet. Quick Summary of the Ketogenic Diet Keto is a high-fat, very-low-carb diet, usually with 70% of calories coming from fat. The idea is to switch your body from using glucose as its primary energy to breaking down fats into ketones for energy. You can measure the macros that you eat and you can measure the ketones in your urine, breath, and blood. In 2013, I did my first experiment with the ketogenic diet. In that experiment, I tracked everything I ate in MyFitnessPal and compared it to other data I was collecting. I found my energy increased, my sleep quality went up (according to my Zeo data), my cholesterol levels improved, and my food cravings went away. However, I also found that measuring everything I ate was a pain, I didn’t really kn Continue reading >>

Ketosis & Measuring Ketones

Ketosis & Measuring Ketones

Generally, ketone concentrations are lower in the morning and higher in the evening. Whatever time you pick to measure ketone levels, make sure to keep it consistent. Also, do not measure your ketone levels right after exercise. Ketone levels tend to be lower while your glucose levels higher so you won't get representative numbers. Keep in mind there are daily fluctuations caused by changes in hormone levels. Don't get discouraged! Another aspect that affects the level of ketones is the amount of fat in your diet. Some of you may show higher concentration of ketones after a high-fat meal. Coconut oil contains MCTs that will help you boost ketones. To easily increase your fat intake on a ketogenic diet, try fat bombs - snacks with at least 80% fat content. Ketone levels tend to be higher after extensive aerobic exercise as your body depletes glycogen stores. Exercise may help you get into ketosis faster. ketogenic "fruity" breath is not pleasant for most people. To avoid this, drink a lot of water, mint tea and make sure you eat foods rich in electrolytes. Avoid too many chewing gums and mints, as it may put you out of ketosis; there may be hidden carbs affecting your blood sugar. Increase your electrolyte intake, especially potassium. You are likely going to lose some sodium and potassium when switching to the keto diet. Finally, if you find it hard to lose weight on a ketogenic diet, there may be plenty other reasons than the level of ketone bodies: Not Losing Weight on Low-Carb Ketogenic Diet? Don’t Give Up and Read Further. Continue reading >>

Ketonuria

Ketonuria

Ketonuria is a medical condition in which ketone bodies are present in the urine. It is seen in conditions in which the body produces excess ketones as an indication that it is using an alternative source of energy. It is seen during starvation or more commonly in type I diabetes mellitus. Production of ketone bodies is a normal response to a shortage of glucose, meant to provide an alternate source of fuel from fatty acids. Pathophysiology[edit] Ketones are metabolic end-products of fatty acid metabolism. In healthy individuals, ketones are formed in the liver and are completely metabolized so that only negligible amounts appear in the urine. However, when carbohydrates are unavailable or unable to be used as an energy source, fat becomes the predominant body fuel instead of carbohydrates and excessive amounts of ketones are formed as a metabolic byproduct. Higher levels of ketones in the urine indicate that the body is using fat as the major source of energy. Ketone bodies that commonly appear in the urine when fats are burned for energy are acetoacetate and beta-hydroxybutyric acid. Acetone is also produced and is expired by the lungs.[1] Normally, the urine should not contain a noticeable concentration of ketones to give a positive reading. As with tests for glucose, acetoacetate can be tested by a dipstick or by a lab. The results are reported as small, moderate, or large amounts of acetoacetate. A small amount of acetoacetate is a value under 20 mg/dl; a moderate amount is a value of 30–40 mg/dl, and a finding of 80 mg/dl or greater is reported as a large amount. One 2010 study admits that though ketonuria's relation to general metabolic health is ill-understood, there is a positive relationship between the presence of ketonuria after fasting and positive metabo Continue reading >>

Ketones

Ketones

Ketones are a beneficial product of fat metabolism in the body. When carbohydrate intake is restricted, it lowers blood sugar and insulin levels. As insulin levels fall and energy is needed, fatty acids flow from the fat cells into the bloodstream and are taken up by various cells and metabolized in a process called beta-oxidation. The end result of beta-oxidation is a molecule called acetyl-coA, and as more fatty acids are released and metabolized, acetyl-coA levels in the cells rise. This causes a sort of metabolic “feedback loop” which triggers liver cells to shunt excess acetyl-Coa into ketogenesis, or the making of ketone bodies. Once created, the liver dumps the ketone bodies into the blood stream and they are taken up by skeletal and heart muscle cells at rates of availability. In addition, the brain begins to use ketones as an alternate fuel when blood levels are high enough to cross the blood brain barrier. Testing Laboratory Microbiology - Air Quality - Mold Asbestos - Environmental - Lead emsl.com There are three major types of ketone bodies present in the human blood stream when the metabolic process of ketosis is dominant: Acetoacetate (AcAc) is created first β-hydroxybutyrate (BHB) is created from acetoacetate Acetone is a spontaneously created side product of acetoacetate In times of starvation, or a low carbohydrate intake resulting in low insulin levels, ketone bodies supply up to 50% of the energy requirements for most body tissues, and up to 70% of the energy required by the brain. Glucose is the main source of fuel for neurons when the diet is high in carbohydrates. But when carbs are restricted, ketogenesis becomes the primary fuel process for most cells. During fasting or low carbohydrate intake, levels of ketone bodies in the blood stream can Continue reading >>

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